Research Topics
| Maoli DuanSummaryAffiliation: Center for Hearing and Communication Research Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Dose and time-dependent protection of the antioxidant N-L-acetylcysteine against impulse noise traumaMaoli Duan
Center for Hearing and Communication Research, Building M1, Karolinska Hospital, SE 171 76 Stockholm, Sweden
Hear Res 192:1-9. 2004..Hair cell loss was significantly reduced using a schedule of three NAC injections in the rats. These results suggest that NAC can partially protect the cochlea against impulse noise trauma...
Low-dose, long-term caroverine administration attenuates impulse noise-induced hearing loss in the ratMaoli Duan
Center for Hearing and Communication Research, Karolinska Hospital, SE 17 176 Stockholm, Sweden
Acta Otolaryngol 126:1140-7. 2006..Physiological and morphological assessments indicated that low-dose and long-term caroverine delivery might be a new approach to protect against impulse noise-induced hearing loss...
A cell therapy approach to substitute neural elements in the inner earMats Ulfendahl
Karolinska Institutet, Center for Hearing and Communication Research, Department of Otolaryngology, Karolinska University Hospital, S 177 76 Stockholm, Sweden
Physiol Behav 92:75-9. 2007..In addition, it is possible that the physical properties of the cochlea, e.g., fluid-filled compartments and very limited space for cell proliferation, are unfavorable, at least in the normal cochlea...
Susceptibility to impulse noise trauma in different species: guinea pig, rat and mouseMaoli Duan
Center for Hearing and Communication Research, Stockholm, Sweden
Acta Otolaryngol 128:277-83. 2008..The results indicate that susceptibility to impulse noise differs in the three species...
Imaging of the guinea pig cochlea following round window gadolinium applicationMaoli Duan
Center for Hearing and Communication Research, Department of Otolaryngology, Karolinska Institutet, 171 76 Stockholm, Sweden
Neuroreport 15:1927-30. 2004..Auditory brainstem response measurements performed on a separate group of animals showed no significant threshold shifts after the application, indicating that gadolinium is non-toxic to the guinea pig cochlea...
Survival and neural differentiation of adult neural stem cells transplanted into the mature inner earZhengqing Hu
Center for Hearing and Communication Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Exp Cell Res 302:40-7. 2005..The results illustrate that adult NSCs can survive and differentiate in the injured inner ear. It also demonstrates the feasibility of gene transfer to generate specific progeny for cell replacement therapy in the inner ear...
Protection of auditory function against noise trauma with local caroverine administration in guinea pigsZhiqiang Chen
Department of Otolaryngology, National University of Singapore, Lower Kent Ridge Road, Singapore
Hear Res 197:131-6. 2004..3 kHz (110 dB SPL) for 1 h. Auditory brainstem responses were measured at regular time intervals afterwards. Caroverine was found to offer significant protection of the cochlear function against noise-induced hearing loss...
Ventral approach to rat inner ear preserves cochlear functionJianxin Qiu
Department of Otolaryngology, Affiliated Hospital of Anhui Medical University, Hefei, China
Acta Otolaryngol 127:240-3. 2007..This technique enabled us to visualize the cochlea without causing damage...
Acute treatment of noise trauma with local caroverine application in the guinea pigZhiqiang Chen
Department of Otolaryngology, National University of Singapore, Singapore
Acta Otolaryngol 123:905-9. 2003..Auditory brainstem responses were recorded at regular time intervals. It was shown that caroverine could significantly decrease hearing impairment after noise trauma when applied 1 but not 24 h after noise exposure...
A guinea pig strain with recessive heredity of deafness, producing normal-hearing heterozygotes with resistance to noise traumaAsa Skjonsberg
Center for Hearing and Communication Research and Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Audiol Neurootol 10:323-30. 2005..This difference was still significant at 4 weeks following noise exposure. It is suggested that the heterozygous animals have an endogenous resistance to auditory stress...
Intact blood-perilymph barrier in the rat after impulse noise traumaGoran F E Laurell
Department of Physiology, Faculte Xavier Bichat, Universite Paris 7, Institut National de la Sante et de la Recherche Medicale, Paris, France
Acta Otolaryngol 128:608-12. 2008..The present findings are contradictory to the theory of an increased permeability in the blood-labyrinth barrier as a result of extensive noise exposure...
Pharmacokinetics of caroverine in the inner ear and its effects on cochlear function after systemic and local administrations in Guinea pigsZhiqiang Chen
Department of Otolaryngology, National University of Singapore, Singapore
Audiol Neurootol 8:49-56. 2003....
[Gene therapy in hereditary hearing loss. Future therapeutic possibility--maybe combined with stem cells]Björn Palmgren
Karolinska Universitetssjukhuset Solna, Stockholm
Lakartidningen 105:2406-10. 2008
