Research Topics
| P BlomstedtSummaryCountry: Sweden Publications
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Publications
Unilateral caudal zona incerta deep brain stimulation for Parkinsonian tremorPatric Blomstedt
Department of Pharmacology and Clinical Neuroscience, Division of Neurosurgery, Umea University, Umea, Sweden
Parkinsonism Relat Disord 18:1062-6. 2012..The aim of the current study was to evaluate cZi DBS in tremor-dominant Parkinson's disease...
Reoperation after failed deep brain stimulation for essential tremorPatric Blomstedt
Department of Pharmacology and Clinical Neuroscience, Section of Neurosurgery, Umea University, Umea, Sweden
World Neurosurg 78:554.e1-5. 2012..To evaluate the effects of reoperation with deep brain stimulation (DBS) in the caudal zona incerta (cZi) in patients with failed DBS in the ventral intermediate (Vim) nucleus of the thalamus for essential tremor...
Intracerebral infections as a complication of deep brain stimulationPatric Blomstedt
Section of Neurosurgery, Department of Pharmacology and Clinical Neuroscience, Umea University, Umea, Sweden
Stereotact Funct Neurosurg 90:92-6. 2012..A review of 20 publications of 3,818 patients focusing on complications of DBS did not reveal one single case. For that reason, we decided to present our own experience of 4 patients with this complication...
Deep brain stimulation of the posterior subthalamic area in the treatment of tremorP Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Acta Neurochir (Wien) 151:31-6. 2009..Even though the clinical series is small, the reported benefits prompted us to explore DBS in this area in the treatment of tremor...
The posterior subthalamic area in the treatment of movement disorders: past, present, and futurePatric Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Neurosurgery 64:1029-38; discussion 1038-42. 2009..We reviewed the literature to investigate the development of surgery in the posterior subthalamic area from the lesional era to the present...
Deep brain stimulation of the subthalamic nucleus versus the zona incerta in the treatment of essential tremorPatric Blomstedt
Department of Clinical Neuroscience, Section of Neurosurgery, Umea University, Umea, Sweden
Acta Neurochir (Wien) 153:2329-35. 2011..The objective of the current study was to evaluate the effect of STN DBS in ET and to compare this to cZi DBS...
Influence of age, gender and severity of tremor on outcome after thalamic and subthalamic DBS for essential tremorPatric Blomstedt
Department of Clinical Neuroscience, Section of Neurosurgery, Umea University, Sweden
Parkinsonism Relat Disord 17:617-20. 2011..However, patients with a more severe tremor at baseline had a higher degree of residual tremor on stimulation. Tremor in the treated hand and hand function were improved with 70% in the Vim group and 89% in the PSA group...
Deep brain stimulation for movement disorders before DBS for movement disordersPatric Blomstedt
Department of Neurosurgery, University Hospital of Umea, Sweden
Parkinsonism Relat Disord 16:429-33. 2010..It is to the credit of the Grenoble Group to have reinvented, modernised and expanded modern DBS in surgical treatment of movement disorders...
Deep brain stimulation in the posterior subthalamic area in the treatment of essential tremorPatric Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Mov Disord 25:1350-6. 2010..Activities of daily living were improved by 66%. No severe complication occurred. Eight patients presented a postoperative mild dysphasia that regressed within days to weeks. DBS in the PSA resulted in a marked reduction of tremor...
A family with a hereditary form of torsion dystonia from northern Sweden treated with bilateral pallidal deep brain stimulationPatric Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Mov Disord 24:2415-9. 2009..The present study confirms the effectiveness of pallidal DBS in a new family with hereditary primary segmental and generalized dystonia...
Pallidal deep brain stimulation in the treatment of Meige syndromeP Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Acta Neurol Scand 118:198-202. 2008..The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published...
Hardware-related complications of deep brain stimulation: a ten year experienceP Blomstedt
Department of Neurosurgery, University Hospital, Umea, Sweden
Acta Neurochir (Wien) 147:1061-4; discussion 1064. 2005..To analyse the occurrence of hardware-related complications in patients with deep brain stimulation (DBS), over a long period of time...
Pallidotomy versus pallidal stimulationPatric Blomstedt
Department of Neurosurgery, University Hospital of Umea, SE 90185 Umeå, Sweden
Parkinsonism Relat Disord 12:296-301. 2006....
Are complications less common in deep brain stimulation than in ablative procedures for movement disorders?Patric Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Stereotact Funct Neurosurg 84:72-81. 2006..Some of the side effects following lesioning are transient and most but not all DBS side effects are reversible. In the Vim DBS is safer than lesioning, while in the pallidum, unilateral lesions are well tolerated...
Dittmar and the history of stereotaxy; or rats, rabbits, and referencesPatric Blomstedt
Department of Neurosurgery, University Hospital, Umea, Sweden
Neurosurgery 60:198-201; discussion 201-2. 2007..quot; In our opinion, it can most properly be classified as a supportive arm...
Acute severe depression induced by intraoperative stimulation of the substantia nigra: a case reportPatric Blomstedt
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden
Parkinsonism Relat Disord 14:253-6. 2008..Repeated blinded stimulations resulted in the same response. Immediate postoperative magnetic resonance imaging (MRI) revealed that the lowest contact of the right electrode was located in the substantia nigra...
Thalamic deep brain stimulation in the treatment of essential tremor: a long-term follow-upP Blomstedt
Department of Neurosurgery, University Hospital of Umea, Umea, Sweden
Br J Neurosurg 21:504-9. 2007..7 to 4.1 and 8.2, respectively. Vim-DBS is an efficient treatment for ET, also after many years of treatment. There is, however, a decreasing effect over time, most noticeable concerning tremor of action...
Deep brain stimulation in the treatment of depressionP Blomstedt
Department of Neurosurgery, University Hospital of Umea, Sweden
Acta Psychiatr Scand 123:4-11. 2011..To present the technique of deep brain stimulation (DBS) and to evaluate the studies conducted on DBS in the treatment of therapy-refractory major depressive disorder (MDD)...
Long-term effect of deep brain stimulation for essential tremor on activities of daily living and health-related quality of lifeG M Hariz
Department of Community Medicine and Rehabilitation, Section of Occupational Therapy, Umea University, Sweden
Acta Neurol Scand 118:387-94. 2008..To report long-term effects of thalamic deep brain stimulation (DBS) on activities of daily living (ADL) and health-related quality of life (HRQoL) in patients with essential tremor (ET)...
Predicting improvement after surgery for palmar hyperhidrosisL O D Koskinen
Department of Pharmacology and Clinical Neuroscience, Division of Neurosurgery, Umea University, Umea, Sweden
Acta Neurol Scand 126:324-8. 2012..The aim of this study was to test the hypothesis that low preoperative scores on The Everyday Life Questionnaire (EDLQ) would predict QoL improvement after surgery...
Deep brain stimulation - effects on swallowing function in Parkinson's diseaseL Kulneff
Division of Speech and Language Pathology, Department of Clinical Sciences, Umea University, Umea, Sweden
Acta Neurol Scand 127:329-36. 2013..The aim of this work was to evaluate the effect of STN DBS on pharyngeal swallowing function in patients with PD using self-estimation and fiberoptic endoscopic evaluation of swallowing...
Complications and side effects of deep brain stimulation in the posterior subthalamic areaA Fytagoridis
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Sweden anders fytagoridis neuro umu se
Stereotact Funct Neurosurg 88:88-93. 2010..In order to evaluate the safety of the procedure, we analyzed our initial 40 patients for complications and side effects...
Swallowing function in Parkinson's patients following Zona Incerta deep brain stimulationS Sundstedt
Division of Speech and Language Pathology, Department of Clinical Sciences, Umea University, Umea, Sweden
Acta Neurol Scand 126:350-6. 2012..There are no former reports including swallowing and cZI DBS...
Overall self-perceived health in Restless legs treated with intrathecal morphineP Lindvall
Department of Clinical Neuroscience, Umea University, Umea, Sweden
Acta Neurol Scand 127:268-73. 2013..Our aim was to quantify the effect on RLS-related symptoms, health and quality of life in three patients treated with intrathecal morphine...
Stimulation-induced side effects in the posterior subthalamic area: distribution, characteristics and visualizationA Fytagoridis
Department of Pharmacology and Clinical Neuroscience, Neurosurgery, Umea University, Umea, Sweden
Clin Neurol Neurosurg 115:65-71. 2013..The aim of the study was to explore the area further by evaluating the spatial distribution and the characteristics of stimulation-induced side effects in this area...
Sympathicotomy affects cutaneous blood flow, temperature, and sympathicus-mediated reflexesL O D Koskinen
Department of Pharmacology and Clinical Neuroscience, Division of Neurosurgery, University of Umea, Sweden
Acta Neurol Scand 118:402-6. 2008..To study the sympathetically mediated effects of transthoracic endoscopic sympathicotomy (TES) in the treatment of severe primary palmar hyperhidrosis...
Intracerebral microvascular measurements during deep brain stimulation implantation using laser Doppler perfusion monitoringKarin Wårdell
Department of Biomedical Engineering, Linkoping University, Linkoping, Sweden
Stereotact Funct Neurosurg 85:279-86. 2007..005) and the perfusion significantly lower (p < 0.005) in positions identified as white matter in the respective MRI batch. The measurements imply that LDPM has the potential to be used as an intracerebral guidance tool...
Dopaminergic therapy promotes lateralized motor activity in the subthalamic area in Parkinson's diseaseAlexandros G Androulidakis
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
Brain 130:457-68. 2007..These findings suggest that dopaminergic therapy restores a more physiological pattern of reactivity in the STN of patients with Parkinson's disease...
Diffuse reflectance spectroscopy measurements for tissue-type discrimination during deep brain stimulationJohan Antonsson
Department of Biomedical Engineering, Linkoping University, Sweden
J Neural Eng 5:185-90. 2008..The results indicate that diffuse reflectance spectroscopy has a potential to be developed to a suitable complement to other intracerebral guidance methods...
Deep-brain stimulation in Parkinson's diseasePatric Blomstedt
N Engl J Med 346:452-3. 2002
