Hans Blom

Summary

Country: Sweden

Publications

  1. ncbi request reprint Parallel fluorescence detection of single biomolecules in microarrays by a diffractive-optical-designed 2 x 2 fan-out element
    Hans Blom
    Department of Microelectronics and Information Technology, Royal Institute of Technology, Kista, Sweden
    Appl Opt 41:3336-42. 2002
  2. ncbi request reprint Parallel flow measurements in microstructures by use of a multifocal 4 x 1 diffractive optical fan-out element
    Hans Blom
    Department of Microelectronics and Information Technology, Royal Institute of Technology, Kista, Sweden
    Appl Opt 41:6614-20. 2002
  3. doi request reprint Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden
    Microsc Res Tech 75:220-8. 2012
  4. doi request reprint Triplet-state investigations of fluorescent dyes at dielectric interfaces using total internal reflection fluorescence correlation spectroscopy
    Hans Blom
    Department of Biomolecular Physics, Royal Institute of Technology, Stockholm, Sweden
    J Phys Chem A 113:5554-66. 2009
  5. doi request reprint Lorentzian spatial intensity distribution in one-photon fluorescence correlation spectroscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, AlbaNova KTH, Roslagstullsbacken 21, 10691 Stockholm, Sweden
    Appl Opt 48:6050-8. 2009
  6. pmc Electrostatic interactions of fluorescent molecules with dielectric interfaces studied by total internal reflection fluorescence correlation spectroscopy
    Hans Blom
    Department of Biomolecular Physics, Royal Institute of Technology, Stockholm, Sweden
    Int J Mol Sci 11:386-406. 2010
  7. doi request reprint Transient state monitoring by total internal reflection fluorescence microscopy
    Thiemo Spielmann
    Experimental Biomolecular Physics, Department of Applied Physics, Royal Institute of Technology, AlbaNova University Center, 106 91 Stockholm, Sweden
    J Phys Chem B 114:4035-46. 2010
  8. ncbi request reprint Monitoring kinetics of highly environment sensitive states of fluorescent molecules by modulated excitation and time-averaged fluorescence intensity recording
    Tor Sandén
    Experimental Biomolecular Physics, Department of Applied Physics, Royal Institute of Technology, AlbaNova University Center, 106 91 Stockholm, Sweden
    Anal Chem 79:3330-41. 2007
  9. pmc Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden
    BMC Neurosci 12:16. 2011
  10. ncbi request reprint Protein-surfactant interactions at hydrophobic interfaces studied with total internal reflection fluorescence correlation spectroscopy (TIR-FCS)
    Andreas W Sonesson
    YKI, Institute for Surface Chemistry, Stockholm, Sweden
    J Colloid Interface Sci 317:449-57. 2008

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Parallel fluorescence detection of single biomolecules in microarrays by a diffractive-optical-designed 2 x 2 fan-out element
    Hans Blom
    Department of Microelectronics and Information Technology, Royal Institute of Technology, Kista, Sweden
    Appl Opt 41:3336-42. 2002
    ..Results of parallel excitation and detection in a high-density microarray of circular wells show single-biomolecule sensitivity in all four foci simultaneously...
  2. ncbi request reprint Parallel flow measurements in microstructures by use of a multifocal 4 x 1 diffractive optical fan-out element
    Hans Blom
    Department of Microelectronics and Information Technology, Royal Institute of Technology, Kista, Sweden
    Appl Opt 41:6614-20. 2002
    ..Transport effects of the diffusion as a function of flow and distance could then also be studied...
  3. doi request reprint Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden
    Microsc Res Tech 75:220-8. 2012
    ..This confined topology may have implications for generation of local sodium gradients and for structural and functional interactions modulating slow synaptic transmission processes...
  4. doi request reprint Triplet-state investigations of fluorescent dyes at dielectric interfaces using total internal reflection fluorescence correlation spectroscopy
    Hans Blom
    Department of Biomolecular Physics, Royal Institute of Technology, Stockholm, Sweden
    J Phys Chem A 113:5554-66. 2009
    ....
  5. doi request reprint Lorentzian spatial intensity distribution in one-photon fluorescence correlation spectroscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, AlbaNova KTH, Roslagstullsbacken 21, 10691 Stockholm, Sweden
    Appl Opt 48:6050-8. 2009
    ..The use of Lorentzian intensity distributions complements conditions where a Gaussian intensity distribution applies, expanding the applicability range of analytical correlation functions...
  6. pmc Electrostatic interactions of fluorescent molecules with dielectric interfaces studied by total internal reflection fluorescence correlation spectroscopy
    Hans Blom
    Department of Biomolecular Physics, Royal Institute of Technology, Stockholm, Sweden
    Int J Mol Sci 11:386-406. 2010
    ..These TIR-FCS results provide an increased understanding of how fluorophores are influenced by the microenvironment of a glass surface, and show a promising approach for characterizing electrostatic interactions at interfaces...
  7. doi request reprint Transient state monitoring by total internal reflection fluorescence microscopy
    Thiemo Spielmann
    Experimental Biomolecular Physics, Department of Applied Physics, Royal Institute of Technology, AlbaNova University Center, 106 91 Stockholm, Sweden
    J Phys Chem B 114:4035-46. 2010
    ..Given the sensitivity of the triplet and photo-oxidized states to oxygen concentrations and not the least to local redox environments, we expect the approach to become an attractive tool for imaging cell metabolism...
  8. ncbi request reprint Monitoring kinetics of highly environment sensitive states of fluorescent molecules by modulated excitation and time-averaged fluorescence intensity recording
    Tor Sandén
    Experimental Biomolecular Physics, Department of Applied Physics, Royal Institute of Technology, AlbaNova University Center, 106 91 Stockholm, Sweden
    Anal Chem 79:3330-41. 2007
    ....
  9. pmc Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy
    Hans Blom
    Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden
    BMC Neurosci 12:16. 2011
    ..The Na+,K+-ATPase plays an important role for ion homeostasis in virtually all mammalian cells, including neurons. Despite this, there is as yet little known about the isoform specific distribution in neurons...
  10. ncbi request reprint Protein-surfactant interactions at hydrophobic interfaces studied with total internal reflection fluorescence correlation spectroscopy (TIR-FCS)
    Andreas W Sonesson
    YKI, Institute for Surface Chemistry, Stockholm, Sweden
    J Colloid Interface Sci 317:449-57. 2008
    ..This indicated that TLL had a higher affinity than BSA for the C18 surface. The study showed that TIR-FCS provides a useful tool to quantify the surfactant effect on proteins adsorption...
  11. ncbi request reprint Parallel single molecule detection with a fully integrated single-photon 2x2 CMOS detector array
    Michael Gösch
    Karolinska Institute, Department of Medical Biochemistry and Biophysics, S 171 77 Stockholm, Sweden
    J Biomed Opt 9:913-21. 2004
    ..The potential of this new technique for high-throughput confocal-detection-based systems is discussed...
  12. ncbi request reprint Dual-color total internal reflection fluorescence cross-correlation spectroscopy
    Marcel Leutenegger
    J Biomed Opt 11:040502. 2006
    ..Further improvements have been achieved through global analysis of the spectroscopic data...
  13. ncbi request reprint Parallel dual-color fluorescence cross-correlation spectroscopy using diffractive optical elements
    Michael Gösch
    Karolinska Institute, Department of Medical Biochemistry and Biophysics, SE 17177 Stockholm
    J Biomed Opt 10:054008. 2005
    ..The fluorescence emission from double-labeled biomolecules is detected by two 2x2 fiber arrays...
  14. ncbi request reprint Fluorescence fluctuation spectroscopy in subdiffraction focal volumes
    Lars Kastrup
    Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    Phys Rev Lett 94:178104. 2005
    ..Our method significantly extends the potential of far-field FFS, including for the noninvasive investigation of molecular reactions at higher concentrations...