Stefan Lofas

Summary

Affiliation: Biacore AB
Country: Sweden

Publications

  1. ncbi Label-free kinetic binding data as a decisive element in drug discovery
    Karl Andersson
    Biacore AB, Rapsgatan 7 SE 75450 Uppsala, Sweden
    Expert Opin Drug Discov 1:439-46. 2006
  2. ncbi Optimizing the hit-to-lead process using SPR analysis
    Stefan Lofas
    Biacore International AB, Uppsala, Sweden
    Assay Drug Dev Technol 2:407-15. 2004
  3. ncbi Flow-mediated on-surface reconstitution of G-protein coupled receptors for applications in surface plasmon resonance biosensors
    Olof P Karlsson
    Department of Biochemistry and Chemistry, Biacore AB, Rapsgatan 7, SE 754 50 Uppsala, Sweden
    Anal Biochem 300:132-8. 2002

Detail Information

Publications3

  1. ncbi Label-free kinetic binding data as a decisive element in drug discovery
    Karl Andersson
    Biacore AB, Rapsgatan 7 SE 75450 Uppsala, Sweden
    Expert Opin Drug Discov 1:439-46. 2006
    ..The promising results found in the literature indicate that kinetic data on drug-protein interactions may soon become a crucial decisive element in modern drug discovery...
  2. ncbi Optimizing the hit-to-lead process using SPR analysis
    Stefan Lofas
    Biacore International AB, Uppsala, Sweden
    Assay Drug Dev Technol 2:407-15. 2004
    ..A number of studies have used SPR biosensors in secondary screening, lead optimization, quantitative structure-activity relationship analysis, and predictive adsorption, distribution, metabolism, excretion, and/or toxicity evaluations...
  3. ncbi Flow-mediated on-surface reconstitution of G-protein coupled receptors for applications in surface plasmon resonance biosensors
    Olof P Karlsson
    Department of Biochemistry and Chemistry, Biacore AB, Rapsgatan 7, SE 754 50 Uppsala, Sweden
    Anal Biochem 300:132-8. 2002
    ..This method can also be used for the easy formation of pure supported lipid bilayers for use in model membrane interaction studies...