- Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRAK-1 in regulation of tumour necrosis factor and interleukin-10 productionM Berglund
Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Scand J Immunol 67:473-9. 2008..Our results demonstrate that IRAK-1 is not necessary for induction of TLR cross-tolerance as judged by TNF production...
- Gender dependent importance of IRAK-1 in dextran sulfate sodium induced colitisMartin Berglund
Dept of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Cell Immunol 259:27-32. 2009..Our results indicate a gender specific effect of IRAK-1 in the DSS-induced colitis, an interesting finding since the Irak-1 gene is located on the X-chromosome and several inflammatory diseases have a gender dependent incidence...
- IL-1 receptor-associated kinase M downregulates DSS-induced colitisMartin Berglund
Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy at Goteborg University, Sweden
Inflamm Bowel Dis 16:1778-86. 2010..We investigate the importance of the Toll-like receptor (TLR) regulating protein IL-1 receptor-associated kinase M (IRAK-M) using the erosive dextran sulfate sodium (DSS)-induced model of colitis...
- Serum interleukin-1 receptor antagonist is an early indicator of colitis onset in Galphai2-deficient miceO H Hultgren
Department of Clinical Immunology, Goteborg University, Guldhedsgatan 10 A, S 413 46 Goteborg, Sweden
World J Gastroenterol 12:621-4. 2006..To study the serum concentration of IL-1beta, IL-1 receptor antagonist (IL-1Ra) and IL-18 in Galphai2-deficient mice at the age of 6 (healthy), 12 (pre-colitic) and 24 wk (colitic) and in healthy control mice...
- The inflammatory response and hyaluronan synthases in the rabbit flexor tendon and tendon sheath following injuryM Berglund
Department of Hand Surgery, Uppsala University Hospital, Uppsala, Sweden
J Hand Surg Eur Vol 32:581-7. 2007..These findings support the concept that healing in the flexor tendon and the sheath involve different molecular events and that each tissue may require unique modifications if healing is to be enhanced and adhesions reduced...