S Basu

Summary

Country: Sweden

Publications

  1. ncbi request reprint Metabolism of 8-iso-prostaglandin F2alpha
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Sweden
    FEBS Lett 428:32-6. 1998
  2. ncbi request reprint Retinol palmitate counteracts oxidative injury during experimental septic shock
    S Basu
    Section of Geriatrics, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Ann Acad Med Singapore 30:265-9. 2001
  3. pmc Raised levels of F(2)-isoprostanes and prostaglandin F(2alpha) in different rheumatic diseases
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Ann Rheum Dis 60:627-31. 2001
  4. ncbi request reprint Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats
    E Sodergren
    Section for Geriatrics Clinical Nutrition Research, PO Box 609, 75125 Uppsala, Sweden
    Eur J Nutr 40:10-6. 2001
  5. ncbi request reprint Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Clin Sci (Lond) 99:511-6. 2000
  6. ncbi request reprint Vitamin E in relation to lipid peroxidation in experimental septic shock
    S Basu
    Department of Geriatrics Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Sweden
    Prostaglandins Leukot Essent Fatty Acids 62:195-9. 2000
  7. ncbi request reprint Development of a novel biomarker of free radical damage in reperfusion injury after cardiac arrest
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, P O Box 609, SE 751 25, Uppsala, Sweden
    FEBS Lett 470:1-6. 2000
  8. ncbi request reprint Oxidative injury induced cyclooxygenase activation in experimental hepatotoxicity
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Uppsala, S 751 25, Sweden
    Biochem Biophys Res Commun 254:764-7. 1999
  9. ncbi request reprint Oxidative injury and survival during endotoxemia
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Sweden
    FEBS Lett 438:159-60. 1998
  10. ncbi request reprint Association between oxidative stress and bone mineral density
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Uppsala University Hospital, S 751 25 Uppsala, Sweden
    Biochem Biophys Res Commun 288:275-9. 2001

Detail Information

Publications31

  1. ncbi request reprint Metabolism of 8-iso-prostaglandin F2alpha
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Sweden
    FEBS Lett 428:32-6. 1998
    ..Thus, 8-iso-PGF2alpha metabolises in the rabbit mainly to several degraded polar metabolites through dehydrogenation at C-15, reduction of delta13-double bond and beta-oxidation, and excretes efficiently into the urine...
  2. ncbi request reprint Retinol palmitate counteracts oxidative injury during experimental septic shock
    S Basu
    Section of Geriatrics, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Ann Acad Med Singapore 30:265-9. 2001
    ....
  3. pmc Raised levels of F(2)-isoprostanes and prostaglandin F(2alpha) in different rheumatic diseases
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Ann Rheum Dis 60:627-31. 2001
    ..To evaluate oxidative injury and inflammatory status in various rheumatic diseases by measuring the levels of isoprostanes and prostaglandins in serum and synovial fluid...
  4. ncbi request reprint Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats
    E Sodergren
    Section for Geriatrics Clinical Nutrition Research, PO Box 609, 75125 Uppsala, Sweden
    Eur J Nutr 40:10-6. 2001
    ..5 mL/kg body)...
  5. ncbi request reprint Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25 Uppsala, Sweden
    Clin Sci (Lond) 99:511-6. 2000
    ..Thus CLA may induce both non-enzymic and enzymic lipid peroxidation in vivo in middle-aged men with abdominal obesity, without any side effects. The consequences of the increased lipid peroxidation after CLA supplementation are unknown...
  6. ncbi request reprint Vitamin E in relation to lipid peroxidation in experimental septic shock
    S Basu
    Department of Geriatrics Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Sweden
    Prostaglandins Leukot Essent Fatty Acids 62:195-9. 2000
    ....
  7. ncbi request reprint Development of a novel biomarker of free radical damage in reperfusion injury after cardiac arrest
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, P O Box 609, SE 751 25, Uppsala, Sweden
    FEBS Lett 470:1-6. 2000
    ..Thus, 8-iso-PGF(2alpha) and 15-keto-dihydro-PGF(2alpha) measurements in jugular bulb plasma may be used as biomarkers for quantification of free radical catalyzed oxidative brain injury and inflammatory response in reperfusion injury...
  8. ncbi request reprint Oxidative injury induced cyclooxygenase activation in experimental hepatotoxicity
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Uppsala, S 751 25, Sweden
    Biochem Biophys Res Commun 254:764-7. 1999
    ..Cyclooxygenase-dependent inflammatory response through PGF2alpha formation in CCl4-induced hepatotoxicity may possibly be a secondary effect to oxidative injury and a conceivable link between inflammatory response and oxidative injury...
  9. ncbi request reprint Oxidative injury and survival during endotoxemia
    S Basu
    Department of Geriatrics, Faculty of Medicine, Uppsala University, Sweden
    FEBS Lett 438:159-60. 1998
    ..Free radical dependent oxidative injury following endotoxin induced inflammation may be the major cause of organ failure and increased mortality...
  10. ncbi request reprint Association between oxidative stress and bone mineral density
    S Basu
    Sections of Geriatrics and Clinical Nutrition Research, Uppsala University Hospital, S 751 25 Uppsala, Sweden
    Biochem Biophys Res Commun 288:275-9. 2001
    ..Our findings establish a biochemical link between increased oxidative stress and reduced bone density and provide a rational for further studies investigating the role of pro- and antioxidants in osteoporosis...
  11. ncbi request reprint Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness
    M Wohlin
    Department of Public Health and Caring Sciences Geriatrics and Clinical Nutrition, Faculty of Medicine, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Cytokine 38:130-6. 2007
    ..It is unknown if various modes of inflammation (cyclooxygenase [COX]-mediated, cytokine-mediated), oxidative stress and anti-oxidants are independently related to CCA-IMT...
  12. ncbi request reprint Propofol (Diprivan-EDTA) counteracts oxidative injury and deterioration of the arterial oxygen tension during experimental septic shock
    S Basu
    Department of Geriatrics and Clinical Nutrition Research, Uppsala University Hospital, S 751 85 Uppsala, Sweden
    Resuscitation 50:341-8. 2001
    ..CONCLUSIONS: Propofol reduced endotoxin-induced free radical mediated and cyclooxygenase catalysed lipid peroxidation significantly. The implication is that propofol counteracts endotoxin-induced deterioration of PaO(2)...
  13. ncbi request reprint Conjugated linoleic acid induces lipid peroxidation in humans
    S Basu
    Section of Geriatrics Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25, Uppsala, Sweden
    FEBS Lett 468:33-6. 2000
    ..Thus, CLA may induce both non-enzymatic and enzymatic lipid peroxidation in vivo. Further studies of the mechanism behind, and the possible consequences of, the increased lipid peroxidation after CLA supplementation are urgently needed...
  14. ncbi request reprint Active smoking and a history of smoking are associated with enhanced prostaglandin F(2alpha), interleukin-6 and F2-isoprostane formation in elderly men
    J Helmersson
    Sections of Geriatrics and Clinical Nutrition Research, Department of Public Health and Caring Sciences, Uppsala University, Sweden
    Atherosclerosis 181:201-7. 2005
    ..Subclinical COX- and cytokine-mediated inflammation and oxidative stress are ongoing processes not only in active smokers but also in former smokers which may contribute to the accelerated atherosclerosis associated with smoking...
  15. doi request reprint Improved neuroprotective effect of methylene blue with hypothermia after porcine cardiac arrest
    L Wiklund
    Departments of Surgical Sciences Anesthesiology and Intensive Care Medicine, Uppsala University, Uppsala, Sweden
    Acta Anaesthesiol Scand 57:1073-82. 2013
    ..We set out to determine if MB administered during CPR could add to the histologic neuroprotective effect of hypothermia...
  16. doi request reprint Serum and dietary beta-carotene and alpha-tocopherol and incidence of type 2 diabetes mellitus in a community-based study of Swedish men: report from the Uppsala Longitudinal Study of Adult Men (ULSAM) study
    J Arnlov
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala Science Park, Uppsala, Sweden
    Diabetologia 52:97-105. 2009
    ..To investigate the association of serum concentrations and dietary intake of beta-carotene and alpha-tocopherol with type 2 diabetes incidence...
  17. ncbi request reprint Differences in cerebral reperfusion and oxidative injury after cardiac arrest in pigs
    X L Liu
    Departments of Anaesthesiology and Intensive Care and Public Health Geriatrics, Uppsala University Hospital, Uppsala, Sweden
    Acta Anaesthesiol Scand 47:958-67. 2003
    ....
  18. pmc Serum cystatin C and the risk of Alzheimer disease in elderly men
    J Sundelof
    Uppsala University, Department of Public Health Geriatrics, Uppsala Science Park, Uppsala, Sweden
    Neurology 71:1072-9. 2008
    ..Multiple lines of research suggest that increased cystatin C activity in the brain protects against the development of Alzheimer disease (AD)...
  19. ncbi request reprint Biomarkers of free radical injury during spinal cord ischemia
    S Basu
    Section of Geriatrics, Faculty of Medicine, Uppsala University, P O Box 69, SE 751 25 Uppsala, Sweden
    FEBS Lett 508:36-8. 2001
    ..Thus, free radical mediated and cyclooxygenase catalysed products of arachidonic acid are increased during spinal cord ischemia as a consequence of oxidative injury and inflammation...
  20. ncbi request reprint Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury?
    X L Liu
    Department of Surgical Sciences Anaesthesiology and Intensive Care, Uppsala University Hospital, Uppsala, Sweden
    Acta Anaesthesiol Scand 46:537-46. 2002
    ..Free radical scavenger alpha-phenyl-N-tert-butyl-nitrone (PBN) and cyclosporine-A (CsA) alleviate neuronal damage after global ischemia. Combining these treatments, we investigated neurological outcome after experimental cardiac arrest...
  21. ncbi request reprint Cyclooxygenase-mediated prostaglandin F2alpha is decreased in an elderly population treated with low-dose aspirin
    J Helmersson
    Section of Clinical Nutrition Research, Public Health and Caring Sciences, Faculty of Medicine, Uppsala University, Kålsängsgränd 10D, P O Box 609, SE 751 25 Uppsala, Sweden
    Prostaglandins Leukot Essent Fatty Acids 72:227-33. 2005
    ..This observation suggests a possible COX-mediated anti-inflammatory effect of low-dose aspirin, which should be further confirmed by intervention studies...
  22. ncbi request reprint Oxidative stress and antioxidant status in type 1 diabetes mellitus
    J Vessby
    Section for Clinical Nutrition Research, Department of Public and Caring Sciences, Uppsala University, Uppsala, Sweden
    J Intern Med 251:69-76. 2002
    ....
  23. ncbi request reprint A diet containing rapeseed oil-based fats does not increase lipid peroxidation in humans when compared to a diet rich in saturated fatty acids
    E Sodergren
    Section for Geriatrics Clinical Nutrition Research, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Eur J Clin Nutr 55:922-31. 2001
    ....
  24. ncbi request reprint Microdialysis-evaluated myocardial cyclooxygenase-mediated inflammation and early circulatory depression in porcine endotoxemia
    D K Mutschler
    Department of Surgical Sciences, Institute of Anesthesiology and Critical Care, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
    Crit Care Med 31:1780-5. 2003
    ..To evaluate the early myocardial biochemical inflammatory response with the microdialysis technique during porcine endotoxemia and to simultaneously monitor systemic hemodynamics...
  25. ncbi request reprint F(2)-isoprostane and prostaglandin F(2 alpha)metabolite excretion rate and day to day variation in healthy humans
    J Helmersson
    Unit of Clinical Nutrition Research, Uppsala University, Sweden
    Prostaglandins Leukot Essent Fatty Acids 65:99-102. 2001
    ....
  26. doi request reprint Sex differences in cerebral injury after severe haemorrhage and ventricular fibrillation in pigs
    E Semenas
    Department of Surgical Sciences Anesthesiology and Intensive Care, Faculty of Medicine, Uppsala University Hospital, S 751 85 Uppsala, Sweden
    Acta Anaesthesiol Scand 54:343-53. 2010
    ..The hypothesis was that cerebral injury is less extensive in female animals, and that this difference is independent of sexual hormones or choice of resuscitative fluid...
  27. ncbi request reprint Increased rate of lipid peroxidation and protein carbonylation in experimental diabetic pregnancy
    J Cederberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Diabetologia 44:766-74. 2001
    ..CONCLUSIONS/INTERPRETATION: In diabetic pregnancy, both diabetes and pregnancy are promoting oxygen radical damage. Fetal oxidative stress markers do not clearly reflect fetal morphology...
  28. ncbi request reprint Increased serum cystatin C is associated with increased mortality in elderly men
    A Larsson
    Section of Clinical Chemistry, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Scand J Clin Lab Invest 65:301-5. 2005
    ..The cystatin C values were significantly correlated with overall mortality (p=0.013). Mortality was three times higher in the highest cystatin C quintile in relation to the lowest quintile...
  29. doi request reprint Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study
    M Degerman Gunnarsson
    Department of Public Health Geriatrics, Uppsala University, Sweden
    Dement Geriatr Cogn Disord 29:204-12. 2010
    ....
  30. ncbi request reprint Oxidative stress and changes in alpha- and gamma-tocopherol levels during coronary artery bypass grafting
    A T Ulus
    Sections of Geriatrics and Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Uppsala, Sweden
    Ann N Y Acad Sci 1031:352-6. 2004
    ..These findings suggest that an increased free radical-induced oxidative stress together with a gradual appearance of antioxidative defense system during and after CPB...
  31. ncbi request reprint Apolipoprotein E epsilon4 genotype is independently associated with increased intima-media thickness in a recessive pattern
    M Wohlin
    Department of Public Health and Caring Sciences Geriatrics and Clinical Nutrition, Faculty of Medicine, Uppsala University, Uppsala Science Park, 751 85, Uppsala, Sweden
    Lipids 42:451-6. 2007
    ....