- Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levelsAzadeh Arabi
Natural Sciences Section, Södertörns University College, S 141 89 Huddinge, Sweden
J Cell Sci 116:1707-17. 2003..Based on these results we propose a model for c-Myc downregulation where c-Myc is sequestered at the nucleoli. Sequestration of c-Myc is accompanied by recruitment of proteasomes and may lead to subsequent degradation...
- c-Myc associates with ribosomal DNA and activates RNA polymerase I transcriptionAzadeh Arabi
Södertörns högskola, S 141 89 Huddinge, Sweden
Nat Cell Biol 7:303-10. 2005..These results suggest that c-Myc coordinates the activity of all three nuclear RNA polymerases, and thereby plays a key role in regulating ribosome biogenesis and cell growth...