Magnus Andersson

Summary

Country: Sweden

Publications

  1. pmc A structural basis for sustained bacterial adhesion: biomechanical properties of CFA/I pili
    Magnus Andersson
    Department of Physics, Umea University, SE 901 87 Umea, Sweden
    J Mol Biol 415:918-28. 2012
  2. ncbi Modeling of the elongation and retraction of Escherichia coli P pili under strain by Monte Carlo simulations
    Oscar Björnham
    Department of Applied Physics and Electronics, Umea University, 901 87 Umea, Sweden
    Eur Biophys J 37:381-91. 2008
  3. doi Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coli are revealed on a single pilus level using force-measuring optical tweezers
    Mickaël Castelain
    Department of Physics, Umea University, SE 90187 Umea, Sweden
    Eur Biophys J 40:305-16. 2011
  4. doi Physical properties of the specific PapG-galabiose binding in E. coli P pili-mediated adhesion
    Oscar Björnham
    Department of Applied Physics and Electronics, Umea University, 90187 Umea, Sweden
    Eur Biophys J 38:245-54. 2009
  5. doi Assessing bacterial adhesion on an individual adhesin and single pili level using optical tweezers
    Ove Axner
    Department of Physics, Umeå Centre for Microbial Research UCMR, Umea University, Umea, Sweden
    Adv Exp Med Biol 715:301-13. 2011
  6. doi Physical properties of biopolymers assessed by optical tweezers: analysis of folding and refolding of bacterial pili
    Magnus Andersson
    Department of Physics Umeå University, SE 901 87 Umea, Sweden
    Chemphyschem 9:221-35. 2008
  7. doi Unfolding and refolding properties of S pili on extraintestinal pathogenic Escherichia coli
    Mickaël Castelain
    Department of Physics, Umea University, 901 87, Umea, Sweden
    Eur Biophys J 39:1105-15. 2010
  8. pmc The shaft of the type 1 fimbriae regulates an external force to match the FimH catch bond
    Johan Zakrisson
    Department of Physics, Umea University, Umea, Sweden
    Biophys J 104:2137-48. 2013
  9. pmc Dynamic force spectroscopy of E. coli P pili
    Magnus Andersson
    Department of Physics and Department of Molecular Biology, Umea University, Umea, Sweden
    Biophys J 91:2717-25. 2006
  10. doi Helix-like biopolymers can act as dampers of force for bacteria in flows
    Johan Zakrisson
    Department of Physics, Umea University, 901 87 Umea, Sweden
    Eur Biophys J 41:551-60. 2012

Collaborators

Detail Information

Publications16

  1. pmc A structural basis for sustained bacterial adhesion: biomechanical properties of CFA/I pili
    Magnus Andersson
    Department of Physics, Umea University, SE 901 87 Umea, Sweden
    J Mol Biol 415:918-28. 2012
    ..Our results indicate that ETEC CFA/I pili are flexible organelles optimized to withstand harsh motion without breaking, resulting in continued attachment to the intestinal epithelium by the pathogenic bacteria that express these pili...
  2. ncbi Modeling of the elongation and retraction of Escherichia coli P pili under strain by Monte Carlo simulations
    Oscar Björnham
    Department of Applied Physics and Electronics, Umea University, 901 87 Umea, Sweden
    Eur Biophys J 37:381-91. 2008
    ....
  3. doi Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coli are revealed on a single pilus level using force-measuring optical tweezers
    Mickaël Castelain
    Department of Physics, Umea University, SE 90187 Umea, Sweden
    Eur Biophys J 40:305-16. 2011
    ..These data suggest that F1C pili are, like P and S pili, evolutionarily selected to primarily withstand the conditions expressed in the upper urinary tract...
  4. doi Physical properties of the specific PapG-galabiose binding in E. coli P pili-mediated adhesion
    Oscar Björnham
    Department of Applied Physics and Electronics, Umea University, 90187 Umea, Sweden
    Eur Biophys J 38:245-54. 2009
    ..The unfolding process of the P pili rod promotes the formation of strong multipili interaction, which is important for the bacterium to maintain attachment to the host cells...
  5. doi Assessing bacterial adhesion on an individual adhesin and single pili level using optical tweezers
    Ove Axner
    Department of Physics, Umeå Centre for Microbial Research UCMR, Umea University, Umea, Sweden
    Adv Exp Med Biol 715:301-13. 2011
    ..This implies that pili constitute an important virulence factor and a possible target for future anti-microbial drugs...
  6. doi Physical properties of biopolymers assessed by optical tweezers: analysis of folding and refolding of bacterial pili
    Magnus Andersson
    Department of Physics Umeå University, SE 901 87 Umea, Sweden
    Chemphyschem 9:221-35. 2008
    ..The information retrieved is also compared with that obtained by atomic force microscopy...
  7. doi Unfolding and refolding properties of S pili on extraintestinal pathogenic Escherichia coli
    Mickaël Castelain
    Department of Physics, Umea University, 901 87, Umea, Sweden
    Eur Biophys J 39:1105-15. 2010
    ..Moreover, we demonstrate that it is possible to distinguish, by analyzing force-extension data, the different types of pili expressed by an individual cell of a clinical bacterial isolate...
  8. pmc The shaft of the type 1 fimbriae regulates an external force to match the FimH catch bond
    Johan Zakrisson
    Department of Physics, Umea University, Umea, Sweden
    Biophys J 104:2137-48. 2013
    ....
  9. pmc Dynamic force spectroscopy of E. coli P pili
    Magnus Andersson
    Department of Physics and Department of Molecular Biology, Umea University, Umea, Sweden
    Biophys J 91:2717-25. 2006
    ..8 Hz, and approximately 8 GHz, respectively. The results also support a previously constructed sticky-chain model for elongation of the PapA rod that until now had been experimentally verified only under steady-state conditions...
  10. doi Helix-like biopolymers can act as dampers of force for bacteria in flows
    Johan Zakrisson
    Department of Physics, Umea University, 901 87 Umea, Sweden
    Eur Biophys J 41:551-60. 2012
    ....
  11. pmc The biomechanical properties of E. coli pili for urinary tract attachment reflect the host environment
    Magnus Andersson
    Department of Physics, Umea University, Umea, Sweden
    Biophys J 93:3008-14. 2007
    ..Our findings highlight functions that are believed to be of importance for the bacterial ability to sustain a basic antimicrobial mechanism of the host and for bacterial colonization...
  12. ncbi Characterization of the biomechanical properties of T4 pili expressed by Streptococcus pneumoniae--a comparison between helix-like and open coil-like pili
    Mickaël Castelain
    Department of Physics, Umea University, SE 901 87 Umea, Sweden
    Chemphyschem 10:1533-40. 2009
    ....
  13. pmc A sticky chain model of the elongation and unfolding of Escherichia coli P pili under stress
    Magnus Andersson
    Department of Physics, Umea University, SE 901 87 Umea, Sweden
    Biophys J 90:1521-34. 2006
    ..Entities such as the free energy, the stiffness, the elastic elongation, the opening length of the various bonds, and the number of PapA units in the rod are determined...
  14. ncbi Dual-trap technique for reduction of low-frequency noise in force measuring optical tweezers
    Markus Klein
    Department of Physics, Umea University, Sweden
    Appl Opt 46:405-12. 2007
    ..It is shown that this dual-trap technique can reduce the noise in the force signal up to 60% depending on detection bandwidth...
  15. pmc P-fimbriae in the presence of anti-PapA antibodies: new insight of antibodies action against pathogens
    Narges Mortezaei
    1 Department of Physics, Umea University, SE 901 87 Umea, Sweden 2
    Sci Rep 3:3393. 2013
    ..We suggest that our assay and results will be a starting point for further investigations aimed at inhibiting sustained bacterial adhesion by antibodies. ..
  16. ncbi Optical tweezers based force measurement system for quantitating binding interactions: system design and application for the study of bacterial adhesion
    Erik Fällman
    Department of Physics, Umea University, SE 901 87 Umea, Sweden
    Biosens Bioelectron 19:1429-37. 2004
    ..Various calibration procedures were implemented in order to provide absolute force measurements. The system has been used to measure the binding forces between Escherichia coli bacterial adhesins and galabiose-functionalized beads...