- Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family membersM Afrakhte
Unit of Pathology, University Hospital, Uppsala, S 751 85, Sweden
Biochem Biophys Res Commun 249:505-11. 1998..Thus, expression of inhibitory Smads is induced by multiple stimuli, including the various TGF-beta family members, whose action they antagonize...
- Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signallingA Nakao
Ludwig Institute for Cancer Research, Uppsala, Sweden
Nature 389:631-5. 1997..TGF-beta rapidly induces expression of Smad7 mRNA, suggesting that Smad7 may participate in a negative feedback loop to control TGF-beta responses...
- Elevated level of gas3 gene expression is correlated with G0 growth arrest in human fibroblastsC Karlsson
Department of Pathology, University Hospital, Uppsala, S 751 85, Sweden
Cell Biol Int 23:351-8. 1999..Furthermore, we found that in two malignant fibrous histiocytoma cell lines, gas3 expression was lower than in normal fibroblasts, suggesting an altered regulation of the gas3 gene in transformed cells...