Dorian R A Swarts

Summary

Publications

  1. doi CD44 and OTP are strong prognostic markers for pulmonary carcinoids
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Clin Cancer Res 19:2197-207. 2013
  2. doi Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities
    Dorian R A Swarts
    Department of Molecular Cell Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Biochim Biophys Acta 1826:255-71. 2012
  3. pmc Deletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Am J Pathol 179:1129-37. 2011
  4. doi An exploration of pathways involved in lung carcinoid progression using gene expression profiling
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands
    Carcinogenesis 34:2726-37. 2013
  5. doi MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids
    Dorian R A Swarts
    Departments of Molecular Cell Biology D R A S, M E R H, F C S R and Pathology E J M S, M v E, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands Applied Research on Cancer NET Research Centre and Department of Pathology and Diagnostics A S, V C, University and Hospital Trust of Verona, 37134 Verona, Italy Laboratory of Bioinformatics and Computational Genomics W V C, Ghent University, Belgium Department of Oncology G G, M P, M V, Division of Pathology, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy and Department of Pathology A P, University of Bern, Bern, Switzerland
    J Clin Endocrinol Metab 99:E374-8. 2014
  6. doi Interobserver variability for the WHO classification of pulmonary carcinoids
    Dorian R A Swarts
    Departments of Molecular Cell Biology Pulmonology Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht Department of Surgery, Maxima Medical Center, Veldhoven, The Netherlands CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands Departments of Pathology, Jeroen Bosch Hospital, s Hertogenbosch Maasstad Hospital, Rotterdam Sint Antonius Hospital, Nieuwegein VU University Medical Center, Amsterdam Departments of Pulmonology, Atrium Medical Center, Heerlen Viecuri Medical Center, Venlo Catharina Hospital, Eindhoven, The Netherlands Department of Oncology, Division of Pathology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Am J Surg Pathol 38:1429-36. 2014

Detail Information

Publications6

  1. doi CD44 and OTP are strong prognostic markers for pulmonary carcinoids
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Clin Cancer Res 19:2197-207. 2013
    ....
  2. doi Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities
    Dorian R A Swarts
    Department of Molecular Cell Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Biochim Biophys Acta 1826:255-71. 2012
    ..This implies the need to reconsider both diagnostic as well as therapeutic approaches for these different groups of malignancies...
  3. pmc Deletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Am J Pathol 179:1129-37. 2011
    ..Thus, there is a strong association of 11q22.3-q25 loss with poorer prognosis, alone or in combination with absence of 9q34.11 alterations (P = 0.0022 and P = 0.00026, respectively)...
  4. doi An exploration of pathways involved in lung carcinoid progression using gene expression profiling
    Dorian R A Swarts
    Department of Molecular Cell Biology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands
    Carcinogenesis 34:2726-37. 2013
    ..We have identified novel pathways underlying malignant progression and validated several genes as being strong prognostic indicators, some of which could serve as putative therapeutic targets. ..
  5. doi MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids
    Dorian R A Swarts
    Departments of Molecular Cell Biology D R A S, M E R H, F C S R and Pathology E J M S, M v E, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands Applied Research on Cancer NET Research Centre and Department of Pathology and Diagnostics A S, V C, University and Hospital Trust of Verona, 37134 Verona, Italy Laboratory of Bioinformatics and Computational Genomics W V C, Ghent University, Belgium Department of Oncology G G, M P, M V, Division of Pathology, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy and Department of Pathology A P, University of Bern, Bern, Switzerland
    J Clin Endocrinol Metab 99:E374-8. 2014
    ..MEN1 gene alterations have been implicated in lung carcinoids, but their effect on gene expression and disease outcome is unknown...
  6. doi Interobserver variability for the WHO classification of pulmonary carcinoids
    Dorian R A Swarts
    Departments of Molecular Cell Biology Pulmonology Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht Department of Surgery, Maxima Medical Center, Veldhoven, The Netherlands CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, The Netherlands Departments of Pathology, Jeroen Bosch Hospital, s Hertogenbosch Maasstad Hospital, Rotterdam Sint Antonius Hospital, Nieuwegein VU University Medical Center, Amsterdam Departments of Pulmonology, Atrium Medical Center, Heerlen Viecuri Medical Center, Venlo Catharina Hospital, Eindhoven, The Netherlands Department of Oncology, Division of Pathology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
    Am J Surg Pathol 38:1429-36. 2014
    ..Additional immunomarkers such as Ki-67 or orthopedia homeobox may improve classification and prediction of prognosis. ..