Soumya Swaminathan

Summary

Publications

  1. pmc Emergence of drug resistant mutations after single dose nevirapine exposure in HIV-1 infected pregnant women in south India
    Lakshmi Rajesh
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 132:509-12. 2010
  2. pmc Diagnosis & treatment of tuberculosis in HIV co-infected patients
    C Padmapriyadarsini
    National Institute for Research in Tuberculosis Indian Council of Medical Research, No 1 Sathiyamoorthy Road, Chetpet, Chennai, India
    Indian J Med Res 134:850-65. 2011
  3. ncbi request reprint Lack of association between plasma levels of non-nucleoside reverse transcriptase inhibitors & virological outcomes during rifampicin co-administration in HIV-infected TB patients
    Geetha Ramachandran
    National Institute for Research in Tuberculosis ICMR, Chennai, India
    Indian J Med Res 138:955-61. 2013
  4. pmc Prevalence of Underweight, Stunting, and Wasting among Children Infected with Human Immunodeficiency Virus in South India
    C Padmapriyadarsini
    Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai 600031, India
    Int J Pediatr 2009:837627. 2009
  5. doi request reprint Profile and response to anti-tuberculosis treatment among elderly tuberculosis patients treated under the TB Control programme in South India
    Banu Rekha Vaithilingam Velayutham
    National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, Chennai, India
    PLoS ONE 9:e88045. 2014
  6. pmc Role of pharmacogenomics in the treatment of tuberculosis: a review
    Geetha Ramachandran
    National Institute for Research in Tuberculosis, Indian Council of Medical Research, Chennai, India
    Pharmgenomics Pers Med 5:89-98. 2012
  7. pmc Efficacy of a six-month versus a 36-month regimen for prevention of tuberculosis in HIV-infected persons in India: a randomized clinical trial
    Soumya Swaminathan
    National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
    PLoS ONE 7:e47400. 2012
  8. doi request reprint Antigen detection as a point-of-care test for TB: the case of lipoarabinomannan
    Soumya Swaminathan
    National Institute for Research in Tuberculosis, Chetpet, Chennai, India
    Future Microbiol 7:559-64. 2012
  9. doi request reprint Efficacy of a 6-month versus 9-month intermittent treatment regimen in HIV-infected patients with tuberculosis: a randomized clinical trial
    Soumya Swaminathan
    Tuberculosis Research Center, Indian Council of Medical Research, Chetput, Chennai, India
    Am J Respir Crit Care Med 181:743-51. 2010
  10. ncbi request reprint Miliary tuberculosis in human immunodeficiency virus infected patients not on antiretroviral therapy: clinical profile and response to shortcourse chemotherapy
    S Swaminathan
    Tuberculosis Research Centre, Chennai, India
    J Postgrad Med 53:228-31. 2007

Collaborators

Detail Information

Publications88

  1. pmc Emergence of drug resistant mutations after single dose nevirapine exposure in HIV-1 infected pregnant women in south India
    Lakshmi Rajesh
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 132:509-12. 2010
    ..Our aim was to study the pattern and prevalence of HIV drug resistance (DR) at baseline (during pregnancy) and after delivery among antenatal women exposed to single dose NVP for prevention of parent to child transmission (PPTCT)...
  2. pmc Diagnosis & treatment of tuberculosis in HIV co-infected patients
    C Padmapriyadarsini
    National Institute for Research in Tuberculosis Indian Council of Medical Research, No 1 Sathiyamoorthy Road, Chetpet, Chennai, India
    Indian J Med Res 134:850-65. 2011
    ..We present here an overview of existing diagnostic strategies, new tests in the pipeline and recommendations for treatment of patients with HIV-TB dual infection...
  3. ncbi request reprint Lack of association between plasma levels of non-nucleoside reverse transcriptase inhibitors & virological outcomes during rifampicin co-administration in HIV-infected TB patients
    Geetha Ramachandran
    National Institute for Research in Tuberculosis ICMR, Chennai, India
    Indian J Med Res 138:955-61. 2013
    ..This study was undertaken to examine the association between plasma nevirapine (NVP) and efavirenz (EFV) concentrations and virological outcomes in patients infected with HIV-1 and TB...
  4. pmc Prevalence of Underweight, Stunting, and Wasting among Children Infected with Human Immunodeficiency Virus in South India
    C Padmapriyadarsini
    Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai 600031, India
    Int J Pediatr 2009:837627. 2009
    ..Conclusions. Undernutrition and stunting are common among HIV-infected children at all stages of the disease in India. Early and aggressive nutritional intervention is required, if long-term outcomes are to be improved...
  5. doi request reprint Profile and response to anti-tuberculosis treatment among elderly tuberculosis patients treated under the TB Control programme in South India
    Banu Rekha Vaithilingam Velayutham
    National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, Chennai, India
    PLoS ONE 9:e88045. 2014
    ..The demographic transition in India has resulted in an increase in the elderly population. There is limited data on the profile of elderly tuberculosis (TB) patients and their treatment outcomes in India...
  6. pmc Role of pharmacogenomics in the treatment of tuberculosis: a review
    Geetha Ramachandran
    National Institute for Research in Tuberculosis, Indian Council of Medical Research, Chennai, India
    Pharmgenomics Pers Med 5:89-98. 2012
    ....
  7. pmc Efficacy of a six-month versus a 36-month regimen for prevention of tuberculosis in HIV-infected persons in India: a randomized clinical trial
    Soumya Swaminathan
    National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
    PLoS ONE 7:e47400. 2012
    ..The optimal duration of preventive therapy for tuberculosis (TB) among HIV-infected persons in TB-endemic countries is unknown...
  8. doi request reprint Antigen detection as a point-of-care test for TB: the case of lipoarabinomannan
    Soumya Swaminathan
    National Institute for Research in Tuberculosis, Chetpet, Chennai, India
    Future Microbiol 7:559-64. 2012
    ..Determine TB-LAM is a simple, low-cost alternative to existing diagnostic assays for TB screening in HIV-infected patients with very low CD4(+) cell counts...
  9. doi request reprint Efficacy of a 6-month versus 9-month intermittent treatment regimen in HIV-infected patients with tuberculosis: a randomized clinical trial
    Soumya Swaminathan
    Tuberculosis Research Center, Indian Council of Medical Research, Chetput, Chennai, India
    Am J Respir Crit Care Med 181:743-51. 2010
    ..The outcome of fully intermittent thrice-weekly antituberculosis treatment of various durations in HIV-associated tuberculosis is unclear...
  10. ncbi request reprint Miliary tuberculosis in human immunodeficiency virus infected patients not on antiretroviral therapy: clinical profile and response to shortcourse chemotherapy
    S Swaminathan
    Tuberculosis Research Centre, Chennai, India
    J Postgrad Med 53:228-31. 2007
    ..An increase in tuberculosis (TB) incidence has been associated with human immunodeficiency virus (HIV)...
  11. ncbi request reprint Tuberculin skin test results in HIV-infected patients in India: implications for latent tuberculosis treatment
    S Swaminathan
    Tuberculosis Research Centre, Chennai, India
    Int J Tuberc Lung Dis 12:168-73. 2008
    ..To evaluate the utility of the tuberculin skin test (TST) in detecting latent and active tuberculosis (TB) among human immunodeficiency virus (HIV) infected patients in South India...
  12. doi request reprint HIV-associated tuberculosis: clinical update
    Soumya Swaminathan
    Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
    Clin Infect Dis 50:1377-86. 2010
    ..Ongoing trials may answer many of these unresolved questions...
  13. doi request reprint Prevalence and pattern of cross-reacting antibodies to HIV in patients with tuberculosis
    Soumya Swaminathan
    Division of HIV AIDS, Tuberculosis Research Center, Indian Council of Medical Research, Chetput, Chennai, India
    AIDS Res Hum Retroviruses 24:941-6. 2008
    ..These findings could have potential implications for the development of diagnostics and vaccines...
  14. ncbi request reprint Immune reconstitution syndrome following initiation of antiretroviral therapy in a patient with HIV infection and multidrug-resistant tuberculosis
    Soumya Swaminathan
    HIV AIDS Division, Tuberculosis Research Centre, Chetput, Chennai, India
    Indian J Chest Dis Allied Sci 47:299-304. 2005
    ..We report a case of immune reconstitution syndrome in response to antiretroviral therapy in a HIV-positive patient on antituberculosis therapy for multidrug-resistant tuberculosis...
  15. ncbi request reprint Anti-tuberculosis drug resistance in patients with HIV and tuberculosis in South India
    S Swaminathan
    Tuberculosis Research Centre, Chennai, Tamil Nadu, India
    Int J Tuberc Lung Dis 9:896-900. 2005
    ..Tuberculosis Research Centre clinics at Chennai and Madurai, Tamil Nadu, South India...
  16. ncbi request reprint HIV and tuberculosis in India
    Soumya Swaminathan
    Deptartment of Clinical Research, Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetput, Chennai 600 031, India
    J Biosci 33:527-37. 2008
    ..This requires good coordination and communication between the TB and AIDS control programs, in India...
  17. ncbi request reprint Nutritional supplementation in HIV-infected individuals in South India: a prospective interventional study
    S Swaminathan
    Dept of Clinical Research, Tuberculosis Research Centre, Chennai, India
    Clin Infect Dis 51:51-7. 2010
    ..Malnutrition in human immunodeficiency virus (HIV)-infected individuals is associated with faster disease progression, higher mortality rates, and suboptimal response to antiretroviral therapy (ART)...
  18. ncbi request reprint Basic concepts in the treatment of tuberculosis
    Soumya Swaminathan
    Tuberculosis Research Centre, Indian Council of Medical Research, Spur Tank Road, Chetput, Chennai, India
    Indian J Pediatr 69:S44-9. 2002
    ....
  19. ncbi request reprint A profile of bacteriologically confirmed pulmonary tuberculosis in children
    Soumya Swaminathan
    Division of HIV AIDS, Tuberculosis Research Centre, Chetput, Chennai, India
    Indian Pediatr 45:743-7. 2008
    ..To describe the clinical profile of children with bacteriologically confirmed tuberculosis...
  20. ncbi request reprint Reduced exercise capacity in non-cystic fibrosis bronchiectasis
    Soumya Swaminathan
    Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetput, Chennai, India
    Indian J Pediatr 70:553-6. 2003
    ..Our aim was to study its functional sequelae and affect on work capacity in children...
  21. ncbi request reprint Age-related changes in blood lymphocyte subsets of south Indian children
    Soumya Swaminathan
    HIV AIDS Division and Immunology Division, Tuberculosis Research Centre, Mayor V R Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
    Natl Med J India 16:249-52. 2003
    ..Reference values are not available for Indian children and there is a need for this information to replace commonly used, but inappropriate, adult lymphocyte subset ranges...
  22. doi request reprint Nutritional status of persons with HIV infection, persons with HIV infection and tuberculosis, and HIV-negative individuals from southern India
    Soumya Swaminathan
    Tuberculosis Research Centre, Chetpet, Chennai, India
    Clin Infect Dis 46:946-9. 2008
    ..Weight loss was associated with loss of fat in female patients and with loss of body cell mass in male patients...
  23. ncbi request reprint Unrecognised tuberculosis in HIV-infected patients: sputum culture is a useful tool
    S Swaminathan
    Division of HIV AIDS, Tuberculosis Research Centre, Chennai, Tamil Nadu, India
    Int J Tuberc Lung Dis 8:896-8. 2004
    ..Six of them had strongly positive tuberculin reactions while four were severely immunosuppressed. Our observation highlights the utility of routine sputum culture in the diagnosis of tuberculosis in high-risk individuals...
  24. ncbi request reprint Tuberculosis in HIV-infected children
    Soumya Swaminathan
    Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetpet, Chennai 600 031, India
    Paediatr Respir Rev 5:225-30. 2004
    ..More studies are required to assess the role of newer diagnostic tests, TB preventive therapy and co-administration of anti-retroviral therapy in the control of TB among HIV-infected children...
  25. doi request reprint Efficacy and safety of once-daily nevirapine- or efavirenz-based antiretroviral therapy in HIV-associated tuberculosis: a randomized clinical trial
    Soumya Swaminathan
    Department of Clinical Research, Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
    Clin Infect Dis 53:716-24. 2011
    ..We studied the safety and efficacy of once-daily NVP, compared with efavirenz (EFV; standard therapy); both drugs were administered in combination with 2 nucleoside reverse-transcriptase inhibitors...
  26. doi request reprint Pediatric tuberculosis: global overview and challenges
    Soumya Swaminathan
    Tuberculosis Research Centre, Chennai, India
    Clin Infect Dis 50:S184-94. 2010
    ..Multicentric trials are urgently required to help develop improved diagnostic strategies and formulate shorter, more effective, safe, and evidence-based regimens for treatment and prevention of drug-susceptible and drug-resistant TB...
  27. ncbi request reprint Long term follow up of HIV-infected patients with tuberculosis treated with 6-month intermittent short course chemotherapy
    Soumya Swaminathan
    Tuberculosis Research Centre, Mayor V R Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
    Natl Med J India 21:3-8. 2008
    ..Tuberculosis occurs in 60%-70% of HIV-positive persons in India. The outcome of HIV-positive patients treated with 6-month intermittent short course antituberculosis regimens in India is not well described...
  28. ncbi request reprint Computerized tomography detects pulmonary lesions in children with normal radiographs diagnosed to have tuberculosis
    Soumya Swaminathan
    Tuberculosis Research Center Indian Council of Medical Research, Chennai, India
    Indian Pediatr 42:258-61. 2005
    ..This report highlights the difficulty in excluding active tuberculosis in children. More studies are required on the role of CT scans in the diagnosis of tuberculosis in children...
  29. ncbi request reprint Short-course chemotherapy for paediatric respiratory tuberculosis: 5-year report
    S Swaminathan
    Division of HIV AIDS, Tuberculosis Research Center Indian Council of Medical Research, Chetput, Chennai 600031, India
    Int J Tuberc Lung Dis 9:693-6. 2005
    ..Short-course chemotherapy in children is safe, effective and well tolerated, and leads to excellent long-term results, with a small proportion of children left with radiological sequelae...
  30. pmc CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodeficiency virus-infected patients in South India
    Geetha Ramachandran
    Department of Clinical Research, Tuberculosis Research Centre, Chetput, Chennai, India
    Antimicrob Agents Chemother 53:863-8. 2009
    ..While a small proportion of patients had subtherapeutic efavirenz levels, the clinical implications are uncertain, as all had good immunological responses to CART...
  31. pmc Decreased bioavailability of rifampin and other antituberculosis drugs in patients with advanced human immunodeficiency virus disease
    Prema Gurumurthy
    HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Mayor V R Ramanathan Rd, Chetput, Chennai 600 031, India
    Antimicrob Agents Chemother 48:4473-5. 2004
    ..HIV and HIV-tuberculosis patients who have diarrhea and cryptosporidial infection exhibit decreased bioavailability of antituberculosis drugs...
  32. doi request reprint Antiretroviral drug-resistant mutations at baseline and at time of failure of antiretroviral therapy in HIV type 1-coinfected TB patients
    Lakshmi Rajesh
    Tuberculosis Research Centre ICMR, Chennai, India
    AIDS Res Hum Retroviruses 25:1179-85. 2009
    ..A once-daily regimen of ddI/3TC/EFZ or NVP results in a specific pattern of NNRTI mutations and negligible thymidine analog mutations (TAMs)...
  33. pmc HIV prevention interventions in Chennai, India: are men who have sex with men being reached?
    Beena Thomas
    Tuberculosis Research Center, Indian Council of Medical Research, Chennai, India
    AIDS Patient Care STDS 23:981-6. 2009
    ....
  34. ncbi request reprint Incomplete immunological recovery following anti-tuberculosis treatment in HIV-infected individuals with active tuberculosis
    L E Hanna
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 129:548-54. 2009
    ..The objective of this study was to correlate plasma levels of immune activation markers with the presence of tuberculosis (TB) in HIV-infected and uninfected individuals, and to study the changes following anti-tuberculosis treatment...
  35. pmc Pharmacokinetics of lamivudine & stavudine in generic fixed-dose combinations in HIV-1 infected adults in India
    A K Hemanth Kumar
    Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 130:451-7. 2009
    ....
  36. doi request reprint Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India
    Geetha Ramachandran
    National Institute for Research in Tuberculosis Indian Council of Medical Research, Chennai, India
    Trop Med Int Health 18:1141-4. 2013
    ..To determine the content of certain antituberculosis (TB) drugs supplied at TB treatment centres of the Revised National TB Control Programme (RNTCP) in the state of Tamil Nadu, India...
  37. pmc Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India
    Chandrasekaran Padmapriyadarsini
    Tuberculosis Research Centre, Chennai, India
    Clin Infect Dis 52:540-6. 2011
    ..Our aim was to study the incidence and pattern of dyslipidemia among human immunodeficiency virus (HIV)-infected patients with tuberculosis (TB) who received once-daily antiretroviral therapy (ART)...
  38. ncbi request reprint Increasing nevirapine dose can overcome reduced bioavailability due to rifampicin coadministration
    Geetha Ramachandran
    HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
    J Acquir Immune Defic Syndr 42:36-41. 2006
    ..Further studies to evaluate the long-term safety of higher dose of nevirapine are required...
  39. pmc The influence of stigma on HIV risk behavior among men who have sex with men in Chennai, India
    Beena Thomas
    Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
    AIDS Care 24:1401-6. 2012
    ..51-9.51; p<0.0001). These findings underscore the need to address psychosocial issues of Indian MSM. Unless issues such as stigma are addressed, effective HIV prevention interventions for this hidden population remain a challenge...
  40. doi request reprint Impact of HIV infection on the recurrence of tuberculosis in South India
    Sujatha Narayanan
    Tuberculosis Research Centre, Indian Council of Medical Research, Chennai 600 031, India
    J Infect Dis 201:691-703. 2010
    ....
  41. ncbi request reprint Urine levels of rifampicin & isoniazid in asymptomatic HIV-positive individuals
    Geetha Ramachandran
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 125:763-6. 2007
    ..The D-xylose absorption test was also carried out to assess the absorptive capacity of intestive...
  42. doi request reprint CD4+ T-lymphocyte count/CD8+ T-lymphocyte count ratio: surrogate for HIV infection in infants?
    Poorana Ganga Devi Navaneethapandian
    National Institute for Research in Tuberculosis, Indian Council of Medical Research, Chennai, India
    J Trop Pediatr 58:394-7. 2012
    ..We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate markers of infant HIV infection...
  43. ncbi request reprint Malabsorption of rifampin and isoniazid in HIV-infected patients with and without tuberculosis
    Prema Gurumurthy
    Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
    Clin Infect Dis 38:280-3. 2004
    ..05), and the correlation between them was significant. Our results indicate that patients with HIV infection and diarrhea and those with HIV infection and TB have malabsorption of rifampin and isoniazid...
  44. pmc HIV in Indian MSM: reasons for a concentrated epidemic & strategies for prevention
    Beena Thomas
    National Institute for Research in Tuberculosis, No 1 Satyamoorthy Road, Chetpet, Chennai, India
    Indian J Med Res 134:920-9. 2011
    ....
  45. ncbi request reprint Serum neopterin levels in HIV infected patients with & without tuberculosis
    Chandra Immanuel
    Tuberculosis Research Centre ICMR, Mayor V R Ramanthan Road, Chetput, Chennai, India
    Indian J Med Res 121:220-5. 2005
    ..In this study we attempted to correlate neopterin levels with the presence of tuberculosis in HIV infected and uninfected individuals and studied the changes after antituberculosis treatment...
  46. pmc Perceptions of tuberculosis patients on provider-initiated HIV testing and counseling--a study from south India
    Beena E Thomas
    Tuberculosis Research Centre, Chennai, India
    PLoS ONE 4:e8389. 2009
    ....
  47. ncbi request reprint Factors associated with willingness to participate in HIV vaccine trials among high-risk populations in South India
    Mohanarani Suhadev
    Tuberculosis Research Center, Mayor VR Ramanathan Road, Chetput, Chennai, India
    AIDS Res Hum Retroviruses 25:217-24. 2009
    ..Addressing barriers and concerns by providing information through appropriate agencies will spell out success for preventive HIVVTs in India...
  48. ncbi request reprint Urine nevirapine as a predictor of antiretroviral adherence
    A K Hemanth Kumar
    HIV AIDS Division, Tuberculosis Research Centre ICMR, Mayor V R Ramanathan Road, Chetput, Chennai 600 031, India
    Indian J Med Res 123:565-8. 2006
    ....
  49. ncbi request reprint Steady-State Pharmacokinetics of Nevirapine in HIV-1 Infected Adults in India
    Geetha Ramachandran
    HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
    J Int Assoc Physicians AIDS Care (Chic Ill) 6:251-4. 2007
    ..Conclusions: Patients' immune status, sex, or BMI had no impact on the pharmacokinetics of nevirapine. Plasma nevirapine concentrations were maintained within the therapeutic range of the drug in the majority of the patients...
  50. ncbi request reprint Characterization of HIV-1 isolates from antiretroviral drug-naive children in southern India
    Lakshmi Soundararajan
    Division of HIV AIDS, Tuberculosis Research Center, Chennai, India
    AIDS Res Hum Retroviruses 23:1119-26. 2007
    ..The currently recommended generic first-line antiretroviral drug combination is an appropriate treatment strategy for HIV-1-infected children in India...
  51. ncbi request reprint Immune Activation Is Associated With Increased Gut Microbial Translocation in Treatment-Naive, HIV-Infected Children in a Resource-Limited Setting
    Sudheesh Pilakka-Kanthikeel
    Department of Microbiology and Immunology, Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL Department of Public Health Sciences, Division of Biostatistics, University of Miami Miller School of Medicine, Miami, FL and Department of Clinical Research, Tuberculosis Research Center, Indian Council of Medical Research, Chennai, India Sudheesh Pilakka Kanthikeel is now with the Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL
    J Acquir Immune Defic Syndr 66:16-24. 2014
    ..Gut damage resulting in microbial translocation (MT) is considered a major cause of immune activation (IA) in HIV infection, but data in children are limited, particularly in the absence of antiretroviral therapy...
  52. ncbi request reprint Persistence of stunting after highly active antiretroviral therapy in HIV-infected children in South India
    N Poorana Ganga Devi
    Tuberculosis Research Centre, Chennai, India
    Indian Pediatr 48:333-4. 2011
    ..Stunting is a common feature of pediatric HIV, both on and off HAART...
  53. pmc Unseen and unheard: predictors of sexual risk behavior and HIV infection among men who have sex with men in Chennai, India
    Beena Thomas
    Tuberculosis Research Center, Indian Council of Medical Research, Chennai, India
    AIDS Educ Prev 21:372-83. 2009
    ..Such programs for MSM in India may need to address culturally-relevant commonly cooccurring psychosocial problems to maximize chances of reducing risk for infection...
  54. ncbi request reprint Immune reconstitution syndrome in a child with TB and HIV
    G Narendran
    Tuberculosis Research Centre, Chetput, Chennai, India
    Indian J Pediatr 73:627-9. 2006
    ..We describe a case of a HIV infected child with tubercular (mediastinal) lymphadenitis with worsening of clinical and radiological features on starting HAART...
  55. doi request reprint Pharmacokinetics of anti-tuberculosis drugs in children
    Geetha Ramachandran
    Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
    Indian J Pediatr 78:435-42. 2011
    ..Studies to examine the impact of nutritional status and HIV infection on the pharmacokinetics of anti-TB drugs in children are needed...
  56. ncbi request reprint Gender differences in sexual behaviour among people living with HIV in Chennai, India
    B E Thomas
    Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 129:690-4. 2009
    ..This study was conducted to gain insight into the gender differences in sexual behaviour patterns among HIV seropositive men and women in south India...
  57. pmc Factors influencing plasma nevirapine levels: a study in HIV-infected children on generic antiretroviral treatment in India
    Soumya Swaminathan
    Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
    J Antimicrob Chemother 66:1354-9. 2011
    ..Nevirapine is an important component of paediatric combination HIV therapy. Adequate drug exposure is necessary in order to achieve long-lasting viral suppression...
  58. ncbi request reprint Effect of anticoagulants on plasma nevirapine and efavirenz concentrations
    Agibothu Kupparam Hemanth Kumar
    HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Tambaram, Chennai, India
    Ther Drug Monit 29:652-4. 2007
    ..05). However, the percent variation in EFV between both types of plasma was <10%. Blood collected in heparin or EDTA Vacutainer tubes could be used for plasma NVP determination...
  59. ncbi request reprint Sputum conversion at the end of intensive phase of Category-1 regimen in the treatment of pulmonary tuberculosis patients with diabetes mellitus or HIV infection: An analysis of risk factors
    V V Banu Rekha
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 126:452-8. 2007
    ....
  60. doi request reprint Immune reconstitution inflammatory syndrome in HIV-infected patients with and without prior tuberculosis
    S Ramesh Kumar
    Tuberculosis Research Centre ICMR, Chennai, India
    Int J STD AIDS 23:419-23. 2012
    ..In this population, IRIS was a common event, more so among patients with prior tuberculosis, and neither the rate of CD4 increase nor the Robertson criteria were useful in predicting its development...
  61. ncbi request reprint HIV & smoking in India
    S Ramesh Kumar
    Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 130:15-22. 2009
    ..Counselling on smoking cessation should be one of the main components of primary care, especially in the management of HIV-infected persons. This review highlights the importance of smoking cessation among HIV-infected persons in India...
  62. ncbi request reprint Antiretroviral therapy and TB
    Soumya Swaminathan
    Division of HIV AIDS, Tuberculosis Research Centre, Chennai, India
    Trop Doct 36:73-9. 2006
    ..Despite the complexities presented by co-infection, many programmes have integrated care and are successfully treating patients with both HIV and TB...
  63. ncbi request reprint Rapid progression of HIV infection in infancy
    N Poorana Ganga Devi
    Tuberculosis Research Center, Chennai, India
    Indian Pediatr 46:53-6. 2009
    ..Our findings of rapid disease progression among perinatally infected HIV positive children underline the importance of early diagnosis and treatment...
  64. ncbi request reprint A pilot study on willingness to participate in future preventive HIV vaccine trials
    Mohanarani Suhadev
    HIV AIDS Division, Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 124:631-40. 2006
    ....
  65. doi request reprint Evaluation of a diagnostic algorithm for sputum smear-negative pulmonary tuberculosis in HIV-infected adults
    Chandrasekaran Padmapriyadarsini
    National Institute for Research in Tuberculosis, Chennai, India
    J Acquir Immune Defic Syndr 63:331-8. 2013
    ..We evaluated the utility of initial CXR in the diagnostic algorithm for symptomatic HIV-infected patients with negative sputum smears...
  66. doi request reprint Resistance-associated epitopes of HIV-1C-highly probable candidates for a multi-epitope vaccine
    Jagadish Chandrabose Sundaramurthi
    Division of Biomedical Informatics, Department of Clinical Research, National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, ICMR, 1, Sathiyamoorthy Road, Chetpet, Chennai, 600031, Tamil Nadu, India
    Immunogenetics 64:767-72. 2012
    ..Further, 9 of the 20 polyfunctional epitopes were found to bind to all three resistance-associated HLA alleles using an additional method, adding worth to their potential as candidates for a vaccine formulation for HIV-1C...
  67. ncbi request reprint Short communication: Influence of active tuberculosis on chemokine and chemokine receptor expression in HIV-infected persons
    Luke Elizabeth Hanna
    Division of HIV AIDS, Tuberculosis Research Centre Indian Council of Medical Research, Chetput, Chennai 600 031, India
    AIDS Res Hum Retroviruses 21:997-1002. 2005
    ..Higher amounts of MIP-1alpha, MIP-1beta, and RANTES were detected in plasma of HIV-1-positive individuals, particularly those with dual infection, although the increase was not found to be statistically significant...
  68. ncbi request reprint Impact of tuberculosis on serum leptin levels in patients with HIV infection
    C Prabha
    Department of Immunology, Tuberculosis Research Centre ICMR, Chetpet, Chennai, India
    Horm Res 63:228-33. 2005
    ..As leptin is involved in the weight regulation and cellular immunity, we investigated the role of leptin levels in the co-infection of HIV and TB (HIV-TB)...
  69. ncbi request reprint Comparison of HPLC & spectrophotometric methods for estimation of antiretroviral drug content in pharmaceutical products
    A K Hemanth Kumar
    Department of Clinical Biochemistry and Pharmacology, Tuberculosis Research Centre ICMR, Chennai, India
    Indian J Med Res 132:390-4. 2010
    ....
  70. pmc Can urine lamivudine be used to monitor antiretroviral treatment adherence?
    Agibothu K Hemanth Kumar
    Tuberculosis Research Centre ICMR Chetput, Chennai, India
    MedGenMed 8:53. 2006
    ..However, this needs to be confirmed on a larger sample size and among patients on once-daily and twice-daily treatment regimens...
  71. ncbi request reprint Mannose binding lectin gene variants and susceptibility to tuberculosis in HIV-1 infected patients of South India
    Kalichamy Alagarasu
    Tuberculosis Research Centre, Indian Council of Medical Research, Mayor V R Ramanathan Road, Chetput, Chennai 600031, India
    Tuberculosis (Edinb) 87:535-43. 2007
    ..Medium MBL expression diplotypes might protect against development of TB in HIV-infected patients...
  72. doi request reprint Improved diagnosis of tuberculosis in HIV-positive patients using RD1-encoded antigen CFP-10
    Parasa V Ramana Rao
    Department of Immunology, Tuberculosis Research Centre ICMR, Mayor V R Ramanathan Road, Chetput, Chennai 600031, India
    Int J Infect Dis 13:613-22. 2009
    ....
  73. ncbi request reprint A study of condom acceptability among men in an urban population in South India
    Beena Elizabeth Thomas
    Division of HIV AIDS, Tuberculosis Research Centre, Indian Council of Medical Research, Chennai
    AIDS Behav 8:215-20. 2004
    ..This indicates the need for developing the "condom habit," as using condoms at the first sexual experience is a strong predictor of future condom use...
  74. ncbi request reprint Preventive therapy for tuberculosis in HIV infected individuals
    C Padmapriyadarsini
    Tuberculosis Research Centre ICMR, Mayor V R Ramanathan Road, Chetput, Chennai 600 031, India
    Indian J Med Res 121:415-23. 2005
    ....
  75. doi request reprint Correlates of relationship, psychological, and sexual behavioral factors for HIV risk among Indian women
    R N Gupta
    Indian Council of Medical Research, Division of Reproductive Health and Nutrition, New Delhi, India
    Cultur Divers Ethnic Minor Psychol 14:256-65. 2008
    ..Implications for future research and culturally relevant interventions are discussed...
  76. ncbi request reprint A simple and rapid liquid chromatography method for simultaneous determination of zidovudine and nevirapine in plasma
    Geetha Ramachandran
    Division of HIV AIDS, Tuberculosis Research Centre, Chetput, Chennai 600031, India
    J Chromatogr B Analyt Technol Biomed Life Sci 843:339-44. 2006
    ..Due to its simplicity, the assay can be used for pharmacokinetic studies and therapeutic drug monitoring in patients taking a combination treatment of zidovudine and nevirapine...
  77. ncbi request reprint Protective efficacy of BCG
    Soumya Swaminathan
    Yakshma Anusandhana Kendra, Tuberculosis Research Center, ICMR, Mayor V R Ramanathan Road, Spurtank Road, Chetput, Chennai, India
    Indian J Pediatr 71:1083-4. 2004
  78. ncbi request reprint Simple and rapid liquid chromatography method for determination of efavirenz in plasma
    Geetha Ramachandran
    Tuberculosis Research Centre, Indian Council of Medical Research, Chetput, Chennai, India
    J Chromatogr B Analyt Technol Biomed Life Sci 835:131-5. 2006
    ..The average recovery of efavirenz from plasma was 101%. Due to its simplicity, the assay can be used for pharmacokinetic studies and therapeutic drug monitoring of efavirenz...
  79. ncbi request reprint Childhood tuberculosis - global epidemiology and the impact of HIV
    Banu Rekha
    Tuberculosis Research Centre, Chetput, Mayor V R Ramanathan Road, Chennai, India
    Paediatr Respir Rev 8:99-106. 2007
    ..As BCG is still the only vaccine available, research needs to be focused on better methods of preventing TB. Furthermore, the development of better diagnostics for infection and disease will improve the management of TB in children...
  80. ncbi request reprint Prevalence of asthma in urban and rural children in Tamil Nadu
    Shibi Chakravarthy
    HIV AIDS Department, Tuberculosis Research Centre ICMR, Mayor V R Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
    Natl Med J India 15:260-3. 2002
    ..We aimed to estimate the prevalence of asthma in children under 12 years of age and to study possible differences in the prevalence of childhood asthma in urban and rural areas of Tamil Nadu...
  81. ncbi request reprint Recurrent herpes zoster in early childhood
    N Poorana Ganga Devi
    Tuberculosis Research Centre, Chennai, India
    Indian J Pediatr 74:774-6. 2007
    ..We report a case of recurrent herpes zoster in a 3-year-old HIV positive child involving T4 dermatome on the first occasion and subsequently involving T10 dermatome. The child responded well to oral acyclovir...
  82. ncbi request reprint Guidelines for use of antiretroviral therapy for HIV infected individuals in India (ART guidelines 2008)
    Sanjay Pujari
    J Assoc Physicians India 56:339-48, 353-71. 2008
  83. ncbi request reprint Analysis of generic antiretroviral formulations manufactured in India
    Geetha Ramachandran
    AIDS 18:1482-4. 2004
  84. pmc Filarial/human immunodeficiency virus coinfection in urban southern India
    Kawsar R Talaat
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Trop Med Hyg 79:558-60. 2008
    ..bancrofti infections among HIV-positive persons was 5-9.5%, and there were no quantitative differences in circulating filarial antigen levels between HIV-positive and HIV-negative filarial-infected patients...
  85. ncbi request reprint Association of human leukocyte antigen-A11 with resistance and B40 and DR2 with susceptibility to HIV-1 infection in south India
    Paramasivam Selvaraj
    J Acquir Immune Defic Syndr 43:497-9. 2006
  86. ncbi request reprint Perceptions of a community sample about participation in future HIV vaccine trials in south India
    Adeline M Nyamathi
    School of Nursing, University of California, Los Angeles, Los Angeles, CA 90095 1702, USA
    AIDS Behav 11:619-27. 2007
    ..The need for education and counseling about the dangers of engaging in risky behavior during and after participating in a future HIV vaccine trial is discussed...
  87. ncbi request reprint Isotype specific antibody response in childhood tuberculosis against purified 38 kDa antigen of Mycobacterium tuberculosis
    B Ramalingam
    J Trop Pediatr 48:188-9. 2002
  88. pmc Study of ABCB1 polymorphism (C3435T) in HIV-1-infected individuals from South India
    Siddharth Bakshi
    Br J Clin Pharmacol 65:791-2. 2008