Efficacy of a six-month versus a 36-month regimen for prevention of tuberculosis in HIV-infected persons in India: a randomized clinical trialSoumya Swaminathan
National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
PLoS ONE 7:e47400. 2012
..The optimal duration of preventive therapy for tuberculosis (TB) among HIV-infected persons in TB-endemic countries is unknown...
Antigen detection as a point-of-care test for TB: the case of lipoarabinomannanSoumya Swaminathan
National Institute for Research in Tuberculosis, Chetpet, Chennai, India
Future Microbiol 7:559-64. 2012
..Determine TB-LAM is a simple, low-cost alternative to existing diagnostic assays for TB screening in HIV-infected patients with very low CD4(+) cell counts...
- Nutritional status of persons with HIV infection, persons with HIV infection and tuberculosis, and HIV-negative individuals from southern India
Soumya Swaminathan
Tuberculosis Research Centre, Chetpet, Chennai, India
Clin Infect Dis 46:946-9. 2008
..Weight loss was associated with loss of fat in female patients and with loss of body cell mass in male patients...
Computerized tomography detects pulmonary lesions in children with normal radiographs diagnosed to have tuberculosisSoumya Swaminathan
Tuberculosis Research Center Indian Council of Medical Research, Chennai, India
Indian Pediatr 42:258-61. 2005
..This report highlights the difficulty in excluding active tuberculosis in children. More studies are required on the role of CT scans in the diagnosis of tuberculosis in children...
- Prevalence and pattern of cross-reacting antibodies to HIV in patients with tuberculosis
Soumya Swaminathan
Division of HIV AIDS, Tuberculosis Research Center, Indian Council of Medical Research, Chetput, Chennai, India
AIDS Res Hum Retroviruses 24:941-6. 2008
..These findings could have potential implications for the development of diagnostics and vaccines...
- Short-course chemotherapy for paediatric respiratory tuberculosis: 5-year report
S Swaminathan
Division of HIV AIDS, Tuberculosis Research Center Indian Council of Medical Research, Chetput, Chennai 600031, India
Int J Tuberc Lung Dis 9:693-6. 2005
..Short-course chemotherapy in children is safe, effective and well tolerated, and leads to excellent long-term results, with a small proportion of children left with radiological sequelae...
- Anti-tuberculosis drug resistance in patients with HIV and tuberculosis in South India
S Swaminathan
Tuberculosis Research Centre, Chennai, Tamil Nadu, India
Int J Tuberc Lung Dis 9:896-900. 2005
..Tuberculosis Research Centre clinics at Chennai and Madurai, Tamil Nadu, South India...
- Immune reconstitution syndrome following initiation of antiretroviral therapy in a patient with HIV infection and multidrug-resistant tuberculosis
Soumya Swaminathan
HIV AIDS Division, Tuberculosis Research Centre, Chetput, Chennai, India
Indian J Chest Dis Allied Sci 47:299-304. 2005
..We report a case of immune reconstitution syndrome in response to antiretroviral therapy in a HIV-positive patient on antituberculosis therapy for multidrug-resistant tuberculosis...
- Long term follow up of HIV-infected patients with tuberculosis treated with 6-month intermittent short course chemotherapy
Soumya Swaminathan
Tuberculosis Research Centre, Mayor V R Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
Natl Med J India 21:3-8. 2008
..Tuberculosis occurs in 60%-70% of HIV-positive persons in India. The outcome of HIV-positive patients treated with 6-month intermittent short course antituberculosis regimens in India is not well described...
- HIV and tuberculosis in India
Soumya Swaminathan
Deptartment of Clinical Research, Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetput, Chennai 600 031, India
J Biosci 33:527-37. 2008
..This requires good coordination and communication between the TB and AIDS control programs, in India...
- A profile of bacteriologically confirmed pulmonary tuberculosis in children
Soumya Swaminathan
Division of HIV AIDS, Tuberculosis Research Centre, Chetput, Chennai, India
Indian Pediatr 45:743-7. 2008
..To describe the clinical profile of children with bacteriologically confirmed tuberculosis...
- Tuberculin skin test results in HIV-infected patients in India: implications for latent tuberculosis treatment
S Swaminathan
Tuberculosis Research Centre, Chennai, India
Int J Tuberc Lung Dis 12:168-73. 2008
..To evaluate the utility of the tuberculin skin test (TST) in detecting latent and active tuberculosis (TB) among human immunodeficiency virus (HIV) infected patients in South India...
- Miliary tuberculosis in human immunodeficiency virus infected patients not on antiretroviral therapy: clinical profile and response to shortcourse chemotherapy
S Swaminathan
Tuberculosis Research Centre, Chennai, India
J Postgrad Med 53:228-31. 2007
..An increase in tuberculosis (TB) incidence has been associated with human immunodeficiency virus (HIV)...
- Basic concepts in the treatment of tuberculosis
Soumya Swaminathan
Tuberculosis Research Centre, Indian Council of Medical Research, Spur Tank Road, Chetput, Chennai, India
Indian J Pediatr 69:S44-9. 2002
....
- Nutritional supplementation in HIV-infected individuals in South India: a prospective interventional study
S Swaminathan
Dept of Clinical Research, Tuberculosis Research Centre, Chennai, India
Clin Infect Dis 51:51-7. 2010
..Malnutrition in human immunodeficiency virus (HIV)-infected individuals is associated with faster disease progression, higher mortality rates, and suboptimal response to antiretroviral therapy (ART)...
- Reduced exercise capacity in non-cystic fibrosis bronchiectasis
Soumya Swaminathan
Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetput, Chennai, India
Indian J Pediatr 70:553-6. 2003
..Our aim was to study its functional sequelae and affect on work capacity in children...
- Age-related changes in blood lymphocyte subsets of south Indian children
Soumya Swaminathan
HIV AIDS Division and Immunology Division, Tuberculosis Research Centre, Mayor V R Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
Natl Med J India 16:249-52. 2003
..Reference values are not available for Indian children and there is a need for this information to replace commonly used, but inappropriate, adult lymphocyte subset ranges...
- Pediatric tuberculosis: global overview and challenges
Soumya Swaminathan
Tuberculosis Research Centre, Chennai, India
Clin Infect Dis 50:S184-94. 2010
..Multicentric trials are urgently required to help develop improved diagnostic strategies and formulate shorter, more effective, safe, and evidence-based regimens for treatment and prevention of drug-susceptible and drug-resistant TB...
- HIV-associated tuberculosis: clinical update
Soumya Swaminathan
Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
Clin Infect Dis 50:1377-86. 2010
..Ongoing trials may answer many of these unresolved questions...
- Unrecognised tuberculosis in HIV-infected patients: sputum culture is a useful tool
S Swaminathan
Division of HIV AIDS, Tuberculosis Research Centre, Chennai, Tamil Nadu, India
Int J Tuberc Lung Dis 8:896-8. 2004
..Six of them had strongly positive tuberculin reactions while four were severely immunosuppressed. Our observation highlights the utility of routine sputum culture in the diagnosis of tuberculosis in high-risk individuals...
- Tuberculosis in HIV-infected children
Soumya Swaminathan
Tuberculosis Research Centre, Mayor VR Ramanathan Road, Chetpet, Chennai 600 031, India
Paediatr Respir Rev 5:225-30. 2004
..More studies are required to assess the role of newer diagnostic tests, TB preventive therapy and co-administration of anti-retroviral therapy in the control of TB among HIV-infected children...
- Efficacy of a 6-month versus 9-month intermittent treatment regimen in HIV-infected patients with tuberculosis: a randomized clinical trial
Soumya Swaminathan
Tuberculosis Research Center, Indian Council of Medical Research, Chetput, Chennai, India
Am J Respir Crit Care Med 181:743-51. 2010
..The outcome of fully intermittent thrice-weekly antituberculosis treatment of various durations in HIV-associated tuberculosis is unclear...
- Efficacy and safety of once-daily nevirapine- or efavirenz-based antiretroviral therapy in HIV-associated tuberculosis: a randomized clinical trial
Soumya Swaminathan
Department of Clinical Research, Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
Clin Infect Dis 53:716-24. 2011
..We studied the safety and efficacy of once-daily NVP, compared with efavirenz (EFV; standard therapy); both drugs were administered in combination with 2 nucleoside reverse-transcriptase inhibitors...
- Decreased bioavailability of rifampin and other antituberculosis drugs in patients with advanced human immunodeficiency virus disease
Prema Gurumurthy
HIV-AIDS Division, Tuberculosis Research Centre (Indian Council of Medical Research, Mayor V.R. Ramanathan Rd, Chetput, Chennai 600 031, India
Antimicrob Agents Chemother 48:4473-5. 2004
..HIV and HIV-tuberculosis patients who have diarrhea and cryptosporidial infection exhibit decreased bioavailability of antituberculosis drugs...
- CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodeficiency virus-infected patients in South India
Geetha Ramachandran
Department of Clinical Research, Tuberculosis Research Centre, Chetput, Chennai, India
Antimicrob Agents Chemother 53:863-8. 2009
..While a small proportion of patients had subtherapeutic efavirenz levels, the clinical implications are uncertain, as all had good immunological responses to CART...
- Incomplete immunological recovery following anti-tuberculosis treatment in HIV-infected individuals with active tuberculosis
L E Hanna
Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 129:548-54. 2009
..The objective of this study was to correlate plasma levels of immune activation markers with the presence of tuberculosis (TB) in HIV-infected and uninfected individuals, and to study the changes following anti-tuberculosis treatment...
- HIV prevention interventions in Chennai, India: are men who have sex with men being reached?
Beena Thomas
Tuberculosis Research Center, Indian Council of Medical Research, Chennai, India
AIDS Patient Care STDS 23:981-6. 2009
....
- Antiretroviral drug-resistant mutations at baseline and at time of failure of antiretroviral therapy in HIV type 1-coinfected TB patients
Lakshmi Rajesh
Tuberculosis Research Centre ICMR, Chennai, India
AIDS Res Hum Retroviruses 25:1179-85. 2009
..A once-daily regimen of ddI/3TC/EFZ or NVP results in a specific pattern of NNRTI mutations and negligible thymidine analog mutations (TAMs)...
- Pharmacokinetics of lamivudine & stavudine in generic fixed-dose combinations in HIV-1 infected adults in India
A K Hemanth Kumar
Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 130:451-7. 2009
....
- Increasing nevirapine dose can overcome reduced bioavailability due to rifampicin coadministration
Geetha Ramachandran
HIV/AIDS Division, Tuberculosis Research Centre (Indian Council of Medical Research, Chennai, India
J Acquir Immune Defic Syndr 42:36-41. 2006
..Further studies to evaluate the long-term safety of higher dose of nevirapine are required...
- Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India
Chandrasekaran Padmapriyadarsini
Tuberculosis Research Centre, Chennai, India
Clin Infect Dis 52:540-6. 2011
..Our aim was to study the incidence and pattern of dyslipidemia among human immunodeficiency virus (HIV)-infected patients with tuberculosis (TB) who received once-daily antiretroviral therapy (ART)...
- The influence of stigma on HIV risk behavior among men who have sex with men in Chennai, India
Beena Thomas
Tuberculosis Research Centre, Indian Council of Medical Research, Chennai, India
AIDS Care 24:1401-6. 2012
..51-9.51; p<0.0001). These findings underscore the need to address psychosocial issues of Indian MSM. Unless issues such as stigma are addressed, effective HIV prevention interventions for this hidden population remain a challenge...
- Urine levels of rifampicin & isoniazid in asymptomatic HIV-positive individuals
Geetha Ramachandran
Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 125:763-6. 2007
..The D-xylose absorption test was also carried out to assess the absorptive capacity of intestive...
- Impact of HIV infection on the recurrence of tuberculosis in South India
Sujatha Narayanan
Tuberculosis Research Centre, Indian Council of Medical Research, Chennai 600 031, India
J Infect Dis 201:691-703. 2010
....
- CD4+ T-lymphocyte count/CD8+ T-lymphocyte count ratio: surrogate for HIV infection in infants?
Poorana Ganga Devi Navaneethapandian
National Institute for Research in Tuberculosis, Indian Council of Medical Research, Chennai, India
J Trop Pediatr 58:394-7. 2012
..We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate markers of infant HIV infection...
- HIV in Indian MSM: reasons for a concentrated epidemic & strategies for prevention
Beena Thomas
National Institute for Research in Tuberculosis, No 1 Satyamoorthy Road, Chetpet, Chennai, India
Indian J Med Res 134:920-9. 2011
....
- Serum neopterin levels in HIV infected patients with & without tuberculosis
Chandra Immanuel
Tuberculosis Research Centre (ICMR, Mayor V.R. Ramanthan Road, Chetput, Chennai, India
Indian J Med Res 121:220-5. 2005
..Though the levels decrease with anti tuberculosis therapy, persistently elevated levels indicate progressive HIV disease and a poor prognosis...
- Diagnosis & treatment of tuberculosis in HIV co-infected patients
C Padmapriyadarsini
National Institute for Research in Tuberculosis Indian Council of Medical Research, No 1 Sathiyamoorthy Road, Chetpet, Chennai, India
Indian J Med Res 134:850-65. 2011
..We present here an overview of existing diagnostic strategies, new tests in the pipeline and recommendations for treatment of patients with HIV-TB dual infection...
- Steady-State Pharmacokinetics of Nevirapine in HIV-1 Infected Adults in India
Geetha Ramachandran
HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
J Int Assoc Physicians AIDS Care (Chic Ill) 6:251-4. 2007
..Conclusions: Patients' immune status, sex, or BMI had no impact on the pharmacokinetics of nevirapine. Plasma nevirapine concentrations were maintained within the therapeutic range of the drug in the majority of the patients...
- Urine nevirapine as a predictor of antiretroviral adherence
A K Hemanth Kumar
HIV/AIDS Division, Tuberculosis Research Centre (ICMR, Mayor V.R. Ramanathan Road, Chetput, Chennai 600 031, India
Indian J Med Res 123:565-8. 2006
..INTERPRETATION & CONCLUSION: In view of its long half-life, NVP gets excreted in urine for a long period of time. Hence, testing spot urine samples for NVP may not be a useful measure to monitor patient adherence to treatment...
- Factors associated with willingness to participate in HIV vaccine trials among high-risk populations in South India
Mohanarani Suhadev
Tuberculosis Research Center, Mayor VR Ramanathan Road, Chetput, Chennai, India
AIDS Res Hum Retroviruses 25:217-24. 2009
..Addressing barriers and concerns by providing information through appropriate agencies will spell out success for preventive HIVVTs in India...
- Characterization of HIV-1 isolates from antiretroviral drug-naive children in southern India
Lakshmi Soundararajan
Division of HIV AIDS, Tuberculosis Research Center, Chennai, India
AIDS Res Hum Retroviruses 23:1119-26. 2007
..The currently recommended generic first-line antiretroviral drug combination is an appropriate treatment strategy for HIV-1-infected children in India...
- Malabsorption of rifampin and isoniazid in HIV-infected patients with and without tuberculosis
Prema Gurumurthy
Tuberculosis Research Centre (Indian Council of Medical Research, Chennai, India
Clin Infect Dis 38:280-3. 2004
..05), and the correlation between them was significant. Our results indicate that patients with HIV infection and diarrhea and those with HIV infection and TB have malabsorption of rifampin and isoniazid...
- Gender differences in sexual behaviour among people living with HIV in Chennai, India
B E Thomas
Department of Clinical Research, Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 129:690-4. 2009
..This study was conducted to gain insight into the gender differences in sexual behaviour patterns among HIV seropositive men and women in south India...
- Factors influencing plasma nevirapine levels: a study in HIV-infected children on generic antiretroviral treatment in India
Soumya Swaminathan
Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
J Antimicrob Chemother 66:1354-9. 2011
..Nevirapine is an important component of paediatric combination HIV therapy. Adequate drug exposure is necessary in order to achieve long-lasting viral suppression...
- Pharmacokinetics of anti-tuberculosis drugs in children
Geetha Ramachandran
Tuberculosis Research Centre Indian Council of Medical Research, Chennai, India
Indian J Pediatr 78:435-42. 2011
..Studies to examine the impact of nutritional status and HIV infection on the pharmacokinetics of anti-TB drugs in children are needed...
- Unseen and unheard: predictors of sexual risk behavior and HIV infection among men who have sex with men in Chennai, India
Beena Thomas
Tuberculosis Research Center, Indian Council of Medical Research, Chennai, India
AIDS Educ Prev 21:372-83. 2009
..Such programs for MSM in India may need to address culturally-relevant commonly cooccurring psychosocial problems to maximize chances of reducing risk for infection...
- Perceptions of tuberculosis patients on provider-initiated HIV testing and counseling--a study from south India
Beena E Thomas
Tuberculosis Research Centre, Chennai, India
PLoS ONE 4:e8389. 2009
....
- Persistence of stunting after highly active antiretroviral therapy in HIV-infected children in South India
N Poorana Ganga Devi
Tuberculosis Research Centre, Chennai, India
Indian Pediatr 48:333-4. 2011
..Stunting is a common feature of pediatric HIV, both on and off HAART...
- Effect of anticoagulants on plasma nevirapine and efavirenz concentrations
Agibothu Kupparam Hemanth Kumar
HIV AIDS Division, Tuberculosis Research Centre Indian Council of Medical Research, Tambaram, Chennai, India
Ther Drug Monit 29:652-4. 2007
..05). However, the percent variation in EFV between both types of plasma was <10%. Blood collected in heparin or EDTA Vacutainer tubes could be used for plasma NVP determination...
- Sputum conversion at the end of intensive phase of Category-1 regimen in the treatment of pulmonary tuberculosis patients with diabetes mellitus or HIV infection: An analysis of risk factors
V V Banu Rekha
Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 126:452-8. 2007
....
- Immune reconstitution syndrome in a child with TB and HIV
G Narendran
Tuberculosis Research Centre, Chetput, Chennai, India
Indian J Pediatr 73:627-9. 2006
..We describe a case of a HIV infected child with tubercular (mediastinal) lymphadenitis with worsening of clinical and radiological features on starting HAART...
- Immune reconstitution inflammatory syndrome in HIV-infected patients with and without prior tuberculosis
S Ramesh Kumar
Tuberculosis Research Centre ICMR, Chennai, India
Int J STD AIDS 23:419-23. 2012
..In this population, IRIS was a common event, more so among patients with prior tuberculosis, and neither the rate of CD4 increase nor the Robertson criteria were useful in predicting its development...
- Emergence of drug resistant mutations after single dose nevirapine exposure in HIV-1 infected pregnant women in south India
Lakshmi Rajesh
Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 132:509-12. 2010
..Our aim was to study the pattern and prevalence of HIV drug resistance (DR) at baseline (during pregnancy) and after delivery among antenatal women exposed to single dose NVP for prevention of parent to child transmission (PPTCT)...
- Rapid progression of HIV infection in infancy
N Poorana Ganga Devi
Tuberculosis Research Center, Chennai, India
Indian Pediatr 46:53-6. 2009
..Our findings of rapid disease progression among perinatally infected HIV positive children underline the importance of early diagnosis and treatment...
- Antiretroviral therapy and TB
Soumya Swaminathan
Division of HIV/AIDS, Tuberculosis Research Centre, Chennai, India
Trop Doct 36:73-9. 2006
..Despite the complexities presented by co-infection, many programmes have integrated care and are successfully treating patients with both HIV and TB...
- A pilot study on willingness to participate in future preventive HIV vaccine trials
Mohanarani Suhadev
HIV/AIDS Division, Tuberculosis Research Centre (ICMR, Chennai, India
Indian J Med Res 124:631-40. 2006
..Barriers and concerns should be dealt with carefully by providing correct information. Also there is a need for more education to ensure participants' understanding of key concepts of HIV vaccine trial...
- HIV & smoking in India
S Ramesh Kumar
Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 130:15-22. 2009
..Counselling on smoking cessation should be one of the main components of primary care, especially in the management of HIV-infected persons. This review highlights the importance of smoking cessation among HIV-infected persons in India...
- Resistance-associated epitopes of HIV-1C-highly probable candidates for a multi-epitope vaccine
Jagadish Chandrabose Sundaramurthi
Division of Biomedical Informatics, Department of Clinical Research, National Institute for Research in Tuberculosis Formerly Tuberculosis Research Centre, ICMR, 1, Sathiyamoorthy Road, Chetpet, Chennai, 600031, Tamil Nadu, India
Immunogenetics 64:767-72. 2012
..Further, 9 of the 20 polyfunctional epitopes were found to bind to all three resistance-associated HLA alleles using an additional method, adding worth to their potential as candidates for a vaccine formulation for HIV-1C...
- Impact of tuberculosis on serum leptin levels in patients with HIV infection
C Prabha
Department of Immunology, Tuberculosis Research Centre (ICMR, Chetpet, Chennai, India
Horm Res 63:228-33. 2005
..CONCLUSION: Thus our finding suggests that the leptin concentrations were strongly associated with BMI and gender but not with the disease state or with the circulating cytokine levels...
- Can urine lamivudine be used to monitor antiretroviral treatment adherence?
Agibothu K Hemanth Kumar
Tuberculosis Research Centre ICMR Chetput, Chennai, India
MedGenMed 8:53. 2006
..However, this needs to be confirmed on a larger sample size and among patients on once-daily and twice-daily treatment regimens...
- Short communication: Influence of active tuberculosis on chemokine and chemokine receptor expression in HIV-infected persons
Luke Elizabeth Hanna
Division of HIV AIDS, Tuberculosis Research Centre Indian Council of Medical Research, Chetput, Chennai 600 031, India
AIDS Res Hum Retroviruses 21:997-1002. 2005
..Higher amounts of MIP-1alpha, MIP-1beta, and RANTES were detected in plasma of HIV-1-positive individuals, particularly those with dual infection, although the increase was not found to be statistically significant...
- Comparison of HPLC & spectrophotometric methods for estimation of antiretroviral drug content in pharmaceutical products
A K Hemanth Kumar
Department of Clinical Biochemistry and Pharmacology, Tuberculosis Research Centre ICMR, Chennai, India
Indian J Med Res 132:390-4. 2010
....
- Preventive therapy for tuberculosis in HIV infected individuals
C Padmapriyadarsini
Tuberculosis Research Centre (ICMR, Mayor V.R. Ramanathan Road, Chetput, Chennai 600 031, India
Indian J Med Res 121:415-23. 2005
....
- Mannose binding lectin gene variants and susceptibility to tuberculosis in HIV-1 infected patients of South India
Kalichamy Alagarasu
Tuberculosis Research Centre, Indian Council of Medical Research, Mayor V R Ramanathan Road, Chetput, Chennai 600031, India
Tuberculosis (Edinb) 87:535-43. 2007
..Medium MBL expression diplotypes might protect against development of TB in HIV-infected patients...
- Improved diagnosis of tuberculosis in HIV-positive patients using RD1-encoded antigen CFP-10
Parasa V Ramana Rao
Department of Immunology, Tuberculosis Research Centre ICMR, Mayor V R Ramanathan Road, Chetput, Chennai 600031, India
Int J Infect Dis 13:613-22. 2009
....
- A simple and rapid liquid chromatography method for simultaneous determination of zidovudine and nevirapine in plasma
Geetha Ramachandran
Division of HIV/AIDS, Tuberculosis Research Centre, Chetput, Chennai 600031, India
J Chromatogr B Analyt Technol Biomed Life Sci 843:339-44. 2006
..Due to its simplicity, the assay can be used for pharmacokinetic studies and therapeutic drug monitoring in patients taking a combination treatment of zidovudine and nevirapine...
- Correlates of relationship, psychological, and sexual behavioral factors for HIV risk among Indian women
R N Gupta
Indian Council of Medical Research, Division of Reproductive Health and Nutrition, New Delhi, India
Cultur Divers Ethnic Minor Psychol 14:256-65. 2008
..Implications for future research and culturally relevant interventions are discussed...
- A study of condom acceptability among men in an urban population in South India
Beena Elizabeth Thomas
Division of HIV/AIDS, Tuberculosis Research Centre, Indian Council of Medical Research, Chennai
AIDS Behav 8:215-20. 2004
..This indicates the need for developing the "condom habit," as using condoms at the first sexual experience is a strong predictor of future condom use...
- Protective efficacy of BCG
Soumya Swaminathan
Yakshma Anusandhana Kendra, Tuberculosis Research Center, ICMR, Mayor V.R. Ramanathan Road, Spurtank Road, Chetput, Chennai, India
Indian J Pediatr 71:1083-4. 2004
- Simple and rapid liquid chromatography method for determination of efavirenz in plasma
Geetha Ramachandran
Tuberculosis Research Centre, Indian Council of Medical Research, Chetput, Chennai, India
J Chromatogr B Analyt Technol Biomed Life Sci 835:131-5. 2006
..The average recovery of efavirenz from plasma was 101%. Due to its simplicity, the assay can be used for pharmacokinetic studies and therapeutic drug monitoring of efavirenz...
- Childhood tuberculosis - global epidemiology and the impact of HIV
Banu Rekha
Tuberculosis Research Centre, Chetput, Mayor V R Ramanathan Road, Chennai, India
Paediatr Respir Rev 8:99-106. 2007
..As BCG is still the only vaccine available, research needs to be focused on better methods of preventing TB. Furthermore, the development of better diagnostics for infection and disease will improve the management of TB in children...
- Prevalence of asthma in urban and rural children in Tamil Nadu
Shibi Chakravarthy
HIV/AIDS Department, Tuberculosis Research Centre (ICMR, Mayor V. R. Ramanathan Road, Chetput, Chennai 600031, Tamil Nadu, India
Natl Med J India 15:260-3. 2002
..Further studies are needed to confirm the difference in prevalence between urban and rural children and also to identify possible causes that could account for the higher urban prevalence of asthma in Tamil Nadu...
- Recurrent herpes zoster in early childhood
N Poorana Ganga Devi
Tuberculosis Research Centre, Chennai, India
Indian J Pediatr 74:774-6. 2007
..We report a case of recurrent herpes zoster in a 3-year-old HIV positive child involving T4 dermatome on the first occasion and subsequently involving T10 dermatome. The child responded well to oral acyclovir...
- Analysis of generic antiretroviral formulations manufactured in India
Geetha Ramachandran
AIDS 18:1482-4. 2004
- Association of human leukocyte antigen-A11 with resistance and B40 and DR2 with susceptibility to HIV-1 infection in south India
Paramasivam Selvaraj
J Acquir Immune Defic Syndr 43:497-9. 2006
- Guidelines for use of antiretroviral therapy for HIV infected individuals in India (ART guidelines 2008)
Sanjay Pujari
J Assoc Physicians India 56:339-48, 353-71. 2008
- Filarial/human immunodeficiency virus coinfection in urban southern India
Kawsar R Talaat
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Trop Med Hyg 79:558-60. 2008
..bancrofti infections among HIV-positive persons was 5-9.5%, and there were no quantitative differences in circulating filarial antigen levels between HIV-positive and HIV-negative filarial-infected patients...
- Perceptions of a community sample about participation in future HIV vaccine trials in south India
Adeline M Nyamathi
School of Nursing, University of California, Los Angeles, Los Angeles, CA 90095 1702, USA
AIDS Behav 11:619-27. 2007
..The need for education and counseling about the dangers of engaging in risky behavior during and after participating in a future HIV vaccine trial is discussed...
- Isotype specific antibody response in childhood tuberculosis against purified 38 kDa antigen of Mycobacterium tuberculosis
B Ramalingam
J Trop Pediatr 48:188-9. 2002
- Study of ABCB1 polymorphism (C3435T) in HIV-1-infected individuals from South India
Siddharth Bakshi
Br J Clin Pharmacol 65:791-2. 2008
