S Sungkanuparph

Summary

Publications

  1. pmc Comparison of predicted susceptibility between genotype and virtual phenotype HIV drug resistance interpretation systems among treatment-naive HIV-infected patients in Asia: TASER-M cohort analysis
    Awachana Jiamsakul
    The Kirby Institute, University of New South Wales, Sydney, Australia
    BMC Res Notes 5:582. 2012
  2. pmc Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database
    Poh Lian Lim
    Tan Tock Seng Hospital, Singapore
    J Int AIDS Soc 15:1. 2012
  3. pmc Long-term treatment outcomes of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who experienced NRTI and NNRTI failure
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi 11000, Thailand
    AIDS Res Ther 9:8. 2012
  4. pmc Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors
    Kathy Petoumenos
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    J Int AIDS Soc 13:51. 2010
  5. pmc Renal impairment after switching from stavudine/lamivudine to tenofovir/lamivudine in NNRTI-based antiretroviral regimens
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    AIDS Res Ther 7:37. 2010
  6. pmc Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    AIDS Res Ther 6:30. 2009
  7. ncbi Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis
    Somnuek Sungkanuparph
    Washington University School of Medicine, St Louis, MO, USA
    Clin Infect Dis 41:1326-32. 2005
  8. ncbi Persistent low-level viraemia and virological failure in HIV-1-infected patients treated with highly active antiretroviral therapy
    S Sungkanuparph
    Washington University School of Medicine, St Louis, MO, USA
    HIV Med 7:437-41. 2006
  9. ncbi HIV-1 drug resistance mutations in children who failed non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:83-8. 2009
  10. ncbi Options for a second-line antiretroviral regimen for HIV type 1-infected patients whose initial regimen of a fixed-dose combination of stavudine, lamivudine, and nevirapine fails
    Somnuek Sungkanuparph
    Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 44:447-52. 2007

Collaborators

Detail Information

Publications80

  1. pmc Comparison of predicted susceptibility between genotype and virtual phenotype HIV drug resistance interpretation systems among treatment-naive HIV-infected patients in Asia: TASER-M cohort analysis
    Awachana Jiamsakul
    The Kirby Institute, University of New South Wales, Sydney, Australia
    BMC Res Notes 5:582. 2012
    ....
  2. pmc Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database
    Poh Lian Lim
    Tan Tock Seng Hospital, Singapore
    J Int AIDS Soc 15:1. 2012
    ..This study examines the proportion of patients in the TREAT Asia HIV Observational Database (TAHOD) receiving PCP prophylaxis, and its effect on PCP and mortality...
  3. pmc Long-term treatment outcomes of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who experienced NRTI and NNRTI failure
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi 11000, Thailand
    AIDS Res Ther 9:8. 2012
    ..abstract:..
  4. pmc Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors
    Kathy Petoumenos
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    J Int AIDS Soc 13:51. 2010
    ..This retrospective survey describes types of cancers diagnosed in HIV-infected subjects in Asia, and assesses risk factors for cancer in HIV-infected subjects using contemporaneous HIV-infected controls without cancer...
  5. pmc Renal impairment after switching from stavudine/lamivudine to tenofovir/lamivudine in NNRTI-based antiretroviral regimens
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    AIDS Res Ther 7:37. 2010
    ..However, knowledge regarding whether there is any difference of the frequency of renal injury between tenofovir/lamivudine/efavirenz and tenofovir/lamivudine/nevirapine is lacking...
  6. pmc Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    AIDS Res Ther 6:30. 2009
    ....
  7. ncbi Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis
    Somnuek Sungkanuparph
    Washington University School of Medicine, St Louis, MO, USA
    Clin Infect Dis 41:1326-32. 2005
    ..Limited data are available for patients treated with nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based regimens...
  8. ncbi Persistent low-level viraemia and virological failure in HIV-1-infected patients treated with highly active antiretroviral therapy
    S Sungkanuparph
    Washington University School of Medicine, St Louis, MO, USA
    HIV Med 7:437-41. 2006
    ....
  9. ncbi HIV-1 drug resistance mutations in children who failed non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:83-8. 2009
    ..The patterns of resistance mutations suggest that 48% of patients need a protease inhibitor-based regimen for the second regimen and didanosine+lamivudine is the most required nucleoside reverse transcriptase inhibitor backbone...
  10. ncbi Options for a second-line antiretroviral regimen for HIV type 1-infected patients whose initial regimen of a fixed-dose combination of stavudine, lamivudine, and nevirapine fails
    Somnuek Sungkanuparph
    Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 44:447-52. 2007
    ..Virological failure with this regimen has become more common, and a second-line regimen needs to be prepared in the national program...
  11. ncbi Evaluating the role of etravirine in the second-line antiretroviral therapy after failing an initial non-nucleoside reverse transcriptase inhibitor-based regimen in a resource-limited setting
    Somnuek Sungkanuparph
    Department of Medicine, Ministry of Public Health, Nonthaburi, Thailand
    Curr HIV Res 6:474-6. 2008
    ..This strategy may be an option for patients who cannot afford or tolerate protease inhibitor. Prospective study to evaluate this strategy should be conducted in resource-limited setting...
  12. ncbi HIV-1 genotype after interruption of non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy and virological response after resumption of the same regimen
    Somnuek Sungkanuparph
    Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Int J STD AIDS 18:832-4. 2007
    ..With this strategy, the same regimen can be used for resumption and also yield good virological and immunological outcomes...
  13. doi Standard-dose efavirenz vs. standard-dose nevirapine in antiretroviral regimens among HIV-1 and tuberculosis co-infected patients who received rifampicin
    W Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    HIV Med 9:294-9. 2008
    ..There is limited comparative data between efavirenz (EFV) 600 mg/day and nevirapine (NVP) 400 mg/day-based antiretroviral therapy (ART) among HIV-1 patients with tuberculosis (TB) and receiving rifampicin...
  14. ncbi Predicting factors for unsuccessful switching from nevirapine to efavirenz in HIV-infected patients who developed nevirapine-associated skin rash
    S Kiertiburanakul
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok 10400, Thailand
    Int J STD AIDS 20:176-9. 2009
    ..14) were significant predicting factors for EFV-associated rash. Two predicting factors for unsuccessful switching from NVP to EFV were found. Patients who have these factors need to have a close follow-up if EFV is substituted...
  15. ncbi Incidence and risk factors of rash associated with efavirenz in HIV-infected patients with preceding nevirapine-associated rash
    W Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    HIV Med 7:378-82. 2006
    ..To determine the incidence and risk factors of rash associated with efavirenz in HIV-infected patients with preceding nevirapine-associated rash...
  16. doi Isoniazid preventive therapy and 4-year incidence of pulmonary tuberculosis among HIV-infected Thai patients
    T Khawcharoenporn
    Division of Infectious Diseases, Faculty of Medicine, Thammasat University Hospital, Pathumthani, Thailand
    Int J Tuberc Lung Dis 16:336-41. 2012
    ..Human immunodeficiency virus (HIV) clinics at two Thai tertiary care medical centres...
  17. ncbi Predictors of immunity after hepatitis A vaccination in HIV-infected persons
    E T Overton
    Washington University School of Medicine, St Louis, MO, USA
    J Viral Hepat 14:189-93. 2007
    ..The low rate of response warrants further research in alternative strategies for HAV vaccination among HIV-infected persons...
  18. ncbi Initiation of antiretroviral therapy in advanced AIDS with active tuberculosis: clinical experiences from Thailand
    S Sungkanuparph
    Department of Medicine, Mahidol University, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand
    J Infect 52:188-94. 2006
    ..To study treatment outcomes of antiretroviral therapy (ART) initiated in advanced HIV-infected patients with active tuberculosis (TB)...
  19. doi HIV-1 drug resistance at virological failure versus immunological failure among patients failing first-line antiretroviral therapy in a resource-limited setting
    S Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Int J STD AIDS 23:316-8. 2012
    ..8% versus 2.9%, P = 0.032). Using IF to diagnose treatment failure is associated with higher HIV-1 RNA levels and a higher rate of Q151M, which can limit the options for second-line ART...
  20. ncbi Nevirapine- versus efavirenz-based highly active antiretroviral therapy regimens in antiretroviral-naïve patients with advanced HIV infection
    W Manosuthi
    Division of Infectious Diseases, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    HIV Med 5:105-9. 2004
    ..To compare virological and immunological responses to nevirapine (NVP)-based and efavirenz (EFV)-based highly active antiretroviral therapy (HAART) regimens in antiretroviral-naïve patients with advanced HIV infection...
  21. pmc Monitoring and impact of fluconazole serum and cerebrospinal fluid concentration in HIV-associated cryptococcal meningitis-infected patients
    W Manosuthi
    Department of Medicine, Bamrasnaradura Infectious Diseases Institute, Nonthaburi, Thailand
    HIV Med 11:276-81. 2010
    ..The aim of the present study was to assess fluconazole pharmacokinetic measures in serum and cerebrospinal fluid (CSF); and the correlation of these measures with clinical outcomes of invasive fungal infections...
  22. doi HIV-1 drug resistance-associated mutations among antiretroviral-naïve Thai patients with chronic HIV-1 infection
    W Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    J Int AIDS Soc 15:18203. 2012
    ..Conclusion: HIV-1 DRAMs, especially to NNRTIs, is emerging in a middle-income country after a widespread use of NNRTI-based ART. HIV genotypic assay prior to ART initiation in patients with chronic HIV-1 infection should be considered...
  23. doi Impact of pharmacogenetic markers of CYP2B6 and clinical factors on plasma efavirenz level in HIV/tuberculosis co-infected Thai patients
    W Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    J Int AIDS Soc 15:18410. 2012
    ..058). Conclusions: Particular SNPs and haplotype of CYP2B6, especially *6/*6, has the greatest impact on efavirenz level in HIV/TB co-infected Thai patients whereas low body weight and concurrent receiving rifampicin have lesser effects...
  24. ncbi Impact of drug-resistant tuberculosis on the survival of HIV-infected patients
    S Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Int J Tuberc Lung Dis 11:325-30. 2007
    ..To determine the effect of drug-resistant tuberculosis (TB) on the survival of human immunodeficiency virus (HIV) infected patients in an area with a high prevalence of TB...
  25. ncbi Tuberculin skin test and isoniazid prophylaxis among health care workers in high tuberculosis prevalence areas
    T Khawcharoenporn
    Division of Infectious Diseases, Faculty of Medicine, Thammasat University Hospital, Pathumthani, Thailand
    Int J Tuberc Lung Dis 15:14-23. 2011
    ....
  26. ncbi Low level of efavirenz in HIV-1-infected Thai adults is associated with the CYP2B6 polymorphism
    C Sukasem
    Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Infection 42:469-74. 2014
    ..In the present study, we assessed the influence of the CYP2B6 polymorphism on the plasma efavirenz level...
  27. ncbi Clinical presentation and medical complication in 59 cases of laboratory-confirmed leptospirosis in Bangkok
    B Ariyapruchya
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:159-64. 2003
    ..The clinical presentation, laboratory findings, medical complication, treatment and outcome are given. Leptospirosis in the urban area is common and should be recognized, particularly in rainy season...
  28. pmc HIV-1 drug resistance mutations among antiretroviral-naive HIV-1-infected patients in Asia: results from the TREAT Asia Studies to Evaluate Resistance-Monitoring Study
    Somnuek Sungkanuparph
    Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 52:1053-7. 2011
    ..8%. Primary HIV drug resistance is emerging after rapid scaling-up of antiretroviral therapy use in Asia...
  29. ncbi Coreceptor tropism determined by genotypic assay in HIV-1 circulating in Thailand, where CRF01_AE predominates
    A Phuphuakrat
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    HIV Med 15:269-75. 2014
    ..Data on coreceptor tropism in non-B HIV-1 subtypes are limited. We studied coreceptor tropism in HIV-1 circulating in Thailand, where CRF01_AE predominates, using a genotypic assay...
  30. ncbi Burkholderia pseudomallei: abscess in an unusual site
    S Kiertiburanakul
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Rama 6 Rd, Bangkok 10400, Thailand
    J Postgrad Med 48:124-6. 2002
    ..Diagnosis of melioidosis arose from the surgical finding and pus culture. Treatment with surgical drainage and ceftazidime followed by co-trimoxazole plus doxycycline had a good clinical outcome...
  31. ncbi A multicentre, randomized, double-blind, placebo-controlled trial of primary cryptococcal meningitis prophylaxis in HIV-infected patients with severe immune deficiency
    P Chetchotisakd
    Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    HIV Med 5:140-3. 2004
    ..To assess the efficacy and survival benefit of low-dose fluconazole (400 mg weekly) for primary prophylaxis for cryptococcal meningitis in patients with advanced HIV infection...
  32. ncbi Factors for predicting successful immune response to hepatitis B vaccination in HIV-1 infected patients
    Prayut Ungulkraiwit
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:680-5. 2007
    ..049) and higher CD4 cell count (p = 0.048) were predictors for successful response to hepatitis B vaccination. Determination of antibody levels after vaccination in HIV-infected patients is warranted...
  33. ncbi Tenofovir resistance among HIV-infected patients failing a fixed-dose combination of stavudine, lamivudine, and nevirapine in a resource-limited setting
    Somnuek Sungkanuparph
    Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    AIDS Patient Care STDS 21:711-4. 2007
  34. ncbi Incidence and risk factors of nevirapine-associated skin rashes among HIV-infected patients with CD4 cell counts <250 cells/microL
    Weerawat Manosuthi
    Department of Medicine, Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Tiwanon Road, Nonthaburi 11000, Thailand
    Int J STD AIDS 18:782-6. 2007
    ..Despite the low baseline in this population, the higher number of baseline CD4 cells is continuously associated with a higher risk for skin rashes...
  35. ncbi Incidence and risk factors of major opportunistic infections after initiation of antiretroviral therapy among advanced HIV-infected patients in a resource-limited setting
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi 11000, Thailand
    J Infect 55:464-9. 2007
    ..To study incidence, risk factors, and impact of major opportunistic infections (OIs) after initiation of antiretroviral therapy (ART)...
  36. ncbi Antiretroviral therapy in AIDS patients with CMV disease: impact on the survival and long-term treatment outcome
    Somnuek Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok 10400, Thailand
    J Infect 56:40-3. 2008
    ..To determine the impact of antiretroviral therapy (ART) on the long-term survival of AIDS patients with CMV disease and evaluate long-term outcomes of ART...
  37. doi Temporary external lumbar drainage for reducing elevated intracranial pressure in HIV-infected patients with cryptococcal meningitis
    Weerawat Manosuthi
    Department of Medicine, Bamrasnaradura Infectious Diseases Institute, Tiwanon Road, Nonthaburi 11000, Thailand
    Int J STD AIDS 19:268-71. 2008
    ..In resource-limited settings, the use of temporary external lumbar drainage is a safe and effective management strategy for intractable elevated ICP in HIV-infected patients with cryptococcal meningitis...
  38. ncbi Plasma levels, safety, and 60-week efficacy of a once-daily double-boosted protease inhibitor regimen of atazanavir, saquinavir, and ritonavir
    Weerawat Manosuthi
    J Acquir Immune Defic Syndr 47:127-9. 2008
  39. pmc Durability of stavudine, lamivudine and nevirapine among advanced HIV-1 infected patients with/without prior co-administration of rifampicin: a 144-week prospective study
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    BMC Infect Dis 8:136. 2008
    ..To date, data on the durability of a regimen of stavudine, lamivudine and nevirapine are very limited, particularly from the resource-limited settings...
  40. ncbi Risk factors for nevirapine-associated rash among HIV-infected patients with low CD4 cell counts in resource-limited settings
    Sasisopin Kiertiburanakul
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Curr HIV Res 6:65-9. 2008
    ..Initiation of NVP in patients with these risks needs closed monitoring...
  41. doi Prevalence and risk factors for developing K65R mutations among HIV-1 infected patients who fail an initial regimen of fixed-dose combination of stavudine, lamivudine, and nevirapine
    Somnuek Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok 10400, Thailand
    J Clin Virol 41:310-3. 2008
    ..K65R mutations that occur after failing this regimen prevent the use of tenofovir, didanosine, and abcavir in the second-line regimen...
  42. ncbi Incidence and risk factors of nevirapine-associated severe hepatitis among HIV-infected patients with CD4 cell counts less than 250 cells/microL
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    J Med Assoc Thai 91:159-65. 2008
    ..To determine incidence and risk factors of nevirapine (NVP)-associated severe hepatitis that led to NVP discontinuation among HIV-infected patients with CD4 < 250 cells/microL...
  43. ncbi Opportunistic infections after the initiation of highly active antiretroviral therapy in advanced AIDS patients in an area with a high prevalence of tuberculosis
    Somnuek Sungkanuparph
    AIDS 17:2129-31. 2003
  44. ncbi A study of seven rule-based algorithms for the interpretation of HIV-1 genotypic resistance data in Thailand
    Vongsakorn Poonpiriya
    Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Virol Methods 151:79-86. 2008
    ..S. Food and Drug Administration (FDA)-approved TRUGENE commercial system...
  45. doi Mortality rate of early versus deferred initiation of antiretroviral therapy in HIV-1-infected patients with cryptococcal meningitis
    Weerawat Manosuthi
    J Acquir Immune Defic Syndr 48:508-9. 2008
  46. ncbi Timing of cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in patients with AIDS and cryptococcal meningitis
    Somnuek Sungkanuparph
    J Acquir Immune Defic Syndr 45:595-6. 2007
  47. ncbi Declining prevalence of drug-resistant tuberculosis among HIV/tuberculosis co-infected patients receiving antiretroviral therapy
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Rama 6 Rd, Bangkok 10400, Thailand
    J Med Assoc Thai 90:884-8. 2007
    ..Antiretroviral therapy (ART) has been more accessible in these countries. The present study aimed to determine the impact of ART on the prevalence of DR-TB among HIV/TB co-infected patients...
  48. ncbi Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons
    Edgar Turner Overton
    Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 41:1045-8. 2005
    ..5%) developed a protective antibody response. In a logistic regression model, only a plasma HIV RNA level of <400 copies/mL at the time of vaccination was associated with a protective antibody response (P=.003)...
  49. ncbi Efavirenz levels and 24-week efficacy in HIV-infected patients with tuberculosis receiving highly active antiretroviral therapy and rifampicin
    Weerawat Manosuthi
    Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    AIDS 19:1481-6. 2005
    ..Concomitant use of efavirenz and rifampicin is common for treatment of HIV and tuberculosis. Plasma efavirenz levels can be reduced by rifampicin, but the appropriate daily dosage of efavirenz is unclear...
  50. pmc Safety and tolerability of nevirapine-based antiretroviral therapy in HIV-infected patients receiving fluconazole for cryptococcal prophylaxis: a retrospective cohort study
    Weerawat Manosuthi
    Bamrasnaradura Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    BMC Infect Dis 5:67. 2005
    ..To compare the adverse events after initiation of NVP-based ART among HIV-infected patients who did not receive fluconazole (group A), received fluconazole 400 mg/week (group B), and received fluconazole 200 mg/day (group C)...
  51. ncbi Antiretroviral resistance among HIV-positive pregnant women who have antiretroviral experience from previous pregnancy
    Edgar T Overton
    AIDS 19:1439. 2005
  52. ncbi Initiation of highly active antiretroviral therapy in advanced AIDS with CD4 < 50 cells/mm3 in a resource-limited setting: efficacy and tolerability
    Somnuek Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Int J STD AIDS 16:243-6. 2005
    ..Twenty two patients (13.8%) had adverse drug events and half of these had to discontinue HAART. Initiation of HAART in advanced AIDS with CD4 cell count < 50 cells/mm3 is effective, safe, and well tolerated and should not be delayed...
  53. ncbi Cryptococcuria as a manifestation of disseminated cryptococcosis and isolated urinary tract infection
    Sasisopin Kiertiburanakul
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Jpn J Infect Dis 57:203-5. 2004
    ..The mortality rate was 64%. In conclusion, cryptococcuria is not extremely rare and can present as a manifestation of disseminated cryptococcosis or isolated urinary tract infection...
  54. ncbi Clinical experience with high success rate of antiretroviral therapy in elderly HIV-infected patients
    Somnuek Sungkanuparph
    Age Ageing 33:520-1. 2004
  55. ncbi Aspergillosis of the central nervous system: a catastrophic opportunistic infection
    Piya Pongbhaesaj
    Division of Neurology, Department of Medicine, Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:119-25. 2004
    ..It remains a catastrophic opportunistic infection in spite of the current intensive and aggressive treatment...
  56. ncbi Rapidly growing mycobacterial infections: spectrum of diseases, antimicrobial susceptibility, pathology and treatment outcomes
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 86:772-80. 2003
    ..A series of cases infected with rapidly growing mycobacteria were studied to reveal the spectrum of disease, antimicrobial susceptibility, pathology, and treatment outcomes...
  57. ncbi Efavirenz-based regimen as treatment of advanced AIDS with cryptococcal meningitis
    Somnuek Sungkanuparph
    J Acquir Immune Defic Syndr 33:118-9. 2003
  58. ncbi Discontinuation of secondary prophylaxis for cryptococcal meningitis in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy: a prospective, multicenter, randomized study
    Asda Vibhagool
    Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 36:1329-31. 2003
    ..At a median of 48 weeks after randomization, there were no episodes of cryptococcal meningitis in either group...
  59. ncbi Concomitant tuberculous and cryptococcal thyroid abscess in a human immunodeficiency virus-infected patient
    Sasisopin Kiertiburanakul
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Scand J Infect Dis 35:68-70. 2003
    ..Atypical presentations of both tuberculosis and cryptococcosis should be considered in areas with a high incidence of these diseases...
  60. ncbi Cryptococcosis in human immunodeficiency virus-negative patients
    Sasisopin Kiertiburanakul
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama 6 Rd, Bangkok 10400, Thailand
    Int J Infect Dis 10:72-8. 2006
    ..To describe the clinical characteristics, treatment, and outcomes of cryptococcosis in HIV-negative patients...
  61. ncbi Efavirenz 600 mg/day versus efavirenz 800 mg/day in HIV-infected patients with tuberculosis receiving rifampicin: 48 weeks results
    Weerawat Manosuthi
    Bamrasnaradura Institute, Ministry of Public Health, Nonthaburi, Thailand
    AIDS 20:131-2. 2006
    ..We report the similar virological and immunological outcomes at 48 weeks between the two groups. Efavirenz 600 mg/day should be sufficient for concurrent use with rifamipicin...
  62. ncbi Immune reconstitution inflammatory syndrome of tuberculosis among HIV-infected patients receiving antituberculous and antiretroviral therapy
    Weerawat Manosuthi
    Department of Medicine, Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Tiwanon Road, Nonthaburi 11000, Thailand
    J Infect 53:357-63. 2006
    ..To determine the frequency, risk factors and mortality rate of immune reconstitution inflammatory syndrome (IRIS) of tuberculosis (TB) in patients co-infected with HIV/TB and receiving antiretroviral therapy (ART)...
  63. ncbi Impact of antiretroviral therapy on the relapse of cryptococcosis and survival of HIV-infected patients with cryptococcal infection
    Ubonvan Jongwutiwes
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Curr HIV Res 5:355-60. 2007
    ..Impact of antiretroviral therapy (ART) on the relapse of cryptococcosis and survival of HIV-infected patients with cryptococcosis has not been well established...
  64. ncbi Lipodystrophy and dyslipidemia in human immunodeficiency virus-infected Thai patients receiving antiretroviral therapy
    Yaowaluk Chuapai
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand
    J Med Assoc Thai 90:452-8. 2007
    ..Lipodystrophy and dyslipidemia are increasing problems in HIV-infected patients receiving antiretroviral therapy (ART)...
  65. ncbi Plasma nevirapine levels and 24-week efficacy of a fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) among Thai HIV-infected patients
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi
    J Med Assoc Thai 90:244-50. 2007
    ..A fixed-dose combination of stavudine, lamivudine, and nevirapine (GPO-VIR) is the most affordable antiretroviral therapy (ART) regimen in Thailand. The data of nevirapine (NVP) level and efficacy of this fixed-dose combination is limited...
  66. ncbi Efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) in Thai HIV-infected patients
    Sasisopin Kiertiburanakul
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 90:237-43. 2007
    ..GPO-VIR, fixed-dose combination of stavudine 30/40 mg, lamivudine 150 mg, and nevirapine 200 mg are widely used in Thailand...
  67. pmc Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand
    BMC Infect Dis 7:14. 2007
    ..The clinical data of plasma NVP level, safety and efficacy of antiretroviral therapy (ART) for the concurrent use of nevirapine (NVP)-based ART and fluconazole (FLU) is scanty...
  68. ncbi Isolated antibody to hepatitis B core antigen in HIV-1 infected patients and a pilot study of vaccination to determine the anamnestic response
    Yongyuth Jongjirawisan
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 89:2028-34. 2006
    ..The present study aimed to determine the prevalence and risk factors of isolated anti-HBc and the anamnestic response to hepatitis B vaccination in this population...
  69. ncbi Nevirapine levels after discontinuation of rifampicin therapy and 60-week efficacy of nevirapine-based antiretroviral therapy in HIV-infected patients with tuberculosis
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    Clin Infect Dis 44:141-4. 2007
    ..There was no statistically significant difference in 60-week antiviral efficacy between these patients and patients receiving nevirapine-based antiretroviral therapy alone (P>.05)...
  70. ncbi Virological and immunological responses of efavirenz-based HAART regimen initiated in HIV-infected patients at CD4 < 100 versus CD4 > or = 100 cells/mm3
    Sasisopin Kiertiburanakul
    Division of lnfectious Diseases, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 89:1381-7. 2006
    ..To compare virological and immunological responsiveness of efavirenz (EFV)-based highly active anti retroviral therapy (HAART) between patients with baseline CD4 < 100 and CD4 > or = 100 cells/mm3...
  71. ncbi Survival rate and risk factors of mortality among HIV/tuberculosis-coinfected patients with and without antiretroviral therapy
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi and Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Acquir Immune Defic Syndr 43:42-6. 2006
    ..The impact of antiretroviral therapy (ART) on survival among patients coinfected with HIV and tuberculosis (TB) has not been well established...
  72. ncbi Plasma nevirapine levels and 24-week efficacy in HIV-infected patients receiving nevirapine-based highly active antiretroviral therapy with or without rifampicin
    Weerawat Manosuthi
    Bamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, 11000, Thailand
    Clin Infect Dis 43:253-5. 2006
    ..Mean plasma nevirapine levels at 8 and 12 weeks were lower in patients receiving rifampicin (P=.048). However, virological and immunological outcomes at 24 weeks were not different between the 2 groups (P>.05)...
  73. ncbi Antifungal susceptibilities of Cryptococcus neoformans cerebrospinal fluid isolates and clinical outcomes of cryptococcal meningitis in HIV-infected patients with/without fluconazole prophylaxis
    Weerawat Manosuthi
    Bamrasnaradura Institute, Ministry of Public Health, Nonthaburi, Thailand
    J Med Assoc Thai 89:795-802. 2006
    ..neoformans) obtained from the CerebroSpinal Fluid (CSF); and clinical outcomes of HIV-infected patients diagnosed with cryptococcal meningitis...
  74. ncbi Prevalence of hepatitis B virus and hepatitis C virus co-infection with human immunodeficiency virus in Thai patients: a tertiary-care-based study
    Somnuek Sungkanuparph
    Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 87:1349-54. 2004
    ..Information regarding prevalence of HBV and HCV co-infection with HIV in Thailand is limited...
  75. ncbi Detection of JC virus infection in progressive multifocal leukoencephalopathy: the first documented case in Thailand
    Taweekiat Dujneungkunakorn
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 85:1139-44. 2002
    ..Qualitative PCR for JCV of CSF showed a positive result. This report emphasizes the yield of PCR, the CSF for JCV in a diagnosis of PML, which may reduce the need for a brain biopsy in such cases...
  76. ncbi Eubacterium bacteremia and colon cancer
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Scand J Infect Dis 34:941-3. 2002
    ..A differential diagnosis of colon cancer should be considered in patients with eubacterium bacteremia...
  77. ncbi Chronic diarrhoea caused by Cryptococcus neoformans in a non-human immunodeficiency virus-infected patient
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Scand J Infect Dis 35:211-2. 2003
    ..Repeated rectal swabs revealed no yeast growth. During follow-up for 4 y, she had no problems with diarrhoea. Chronic diarrhoea caused by C. neoformans is rare and clinical suspicion is needed...
  78. ncbi Infections with rapidly growing mycobacteria: report of 20 cases
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Int J Infect Dis 7:198-205. 2003
    ..A series of cases infected with rapidly growing mycobacteria was studied to determine the spectrum of disease, antimicrobial susceptibility, treatment, and outcome...
  79. ncbi Risk factors for strongyloidiasis hyperinfection and clinical outcomes
    Nakhon Asdamongkol
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 37:875-84. 2006
    ..1-20.0, p = 0.001). Most of the patients were treated with albendazole or thiabendazole, with a cure rate of 76.9%, whereas other recent cases treated with ivermectin had an average cure rate of 83.3%. The overall mortality rate was 8.1%...
  80. ncbi Correlation between susceptibility of Mycobacterium tuberculosis by microtiter plate alamar blue assay and clinical outcomes
    Somnuek Sungkanuparph
    Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:820-4. 2002
    ..004). Studies to determine this correlation in pulmonary tuberculosis are still needed...