Yi Cheng Sun

Summary

Publications

  1. pmc The Yersinia pestis Rcs phosphorelay inhibits biofilm formation by repressing transcription of the diguanylate cyclase gene hmsT
    Yi Cheng Sun
    MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Bacteriol 194:2020-6. 2012
  2. pmc Differential control of Yersinia pestis biofilm formation in vitro and in the flea vector by two c-di-GMP diguanylate cyclases
    Yi Cheng Sun
    Laboratory of Zoonotic Pathogens, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
    PLoS ONE 6:e19267. 2011
  3. ncbi request reprint HmsC, a periplasmic protein, controls biofilm formation via repression of HmsD, a diguanylate cyclase in Yersinia pestis
    Gai Xian Ren
    MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 9, Dongdan Santiao, Dongcheng District, Beijing, 100730, China
    Environ Microbiol 16:1202-16. 2014
  4. pmc Retracing the evolutionary path that led to flea-borne transmission of Yersinia pestis
    Yi Cheng Sun
    Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4 th Street, Hamilton, MT 59840, USA
    Cell Host Microbe 15:578-86. 2014

Collaborators

Detail Information

Publications4

  1. pmc The Yersinia pestis Rcs phosphorelay inhibits biofilm formation by repressing transcription of the diguanylate cyclase gene hmsT
    Yi Cheng Sun
    MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Bacteriol 194:2020-6. 2012
    ..Biofilm development is negatively regulated by the Rcs phosphorelay signal transduction system. In this study, we show that Rcs-negative regulation is accomplished by repressing transcription of hmsT...
  2. pmc Differential control of Yersinia pestis biofilm formation in vitro and in the flea vector by two c-di-GMP diguanylate cyclases
    Yi Cheng Sun
    Laboratory of Zoonotic Pathogens, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
    PLoS ONE 6:e19267. 2011
    ..pestis, indicate that hmsT and y3730 are regulated post-transcriptionally to differentially control biofilm formation in vitro and in the flea vector, and identify a second c-di-GMP-regulated phenotype in Y. pestis...
  3. ncbi request reprint HmsC, a periplasmic protein, controls biofilm formation via repression of HmsD, a diguanylate cyclase in Yersinia pestis
    Gai Xian Ren
    MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 9, Dongdan Santiao, Dongcheng District, Beijing, 100730, China
    Environ Microbiol 16:1202-16. 2014
    ..We propose that HmsC senses the environmental signals, which in turn regulates HmsD, and controls the c-di-GMP synthesis and biofilm formation in Y.‚ÄČpestis. ..
  4. pmc Retracing the evolutionary path that led to flea-borne transmission of Yersinia pestis
    Yi Cheng Sun
    Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4 th Street, Hamilton, MT 59840, USA
    Cell Host Microbe 15:578-86. 2014
    ..pestis emerged as a flea-borne clone, with each genetic change incrementally reinforcing the transmission cycle. The model conforms well to the ecological theory of adaptive radiation...