Li R, Weng J, Wang X, Meng Q, Wang Y, Sun J. Bursicon homodimers induce innate immune by activating the expression of anti-microbial peptide genes in the shrimp Neocaridina heteropoda. Fish Shellfish Immunol. 2018;84:906-911 pubmed publisher
..These findings demonstrate a novel function of bursicon in crustacean that it induces innate immune via up-regulating the expression of genes encoding AMPs. ..
Zuo Z, Shang B, Shao Y, Li W, Sun J. Screening of intestinal probiotics and the effects of feeding probiotics on the growth, immune, digestive enzyme activity and intestinal flora of Litopenaeus vannamei. Fish Shellfish Immunol. 2018;86:160-168 pubmed publisher
..vannamei intestines at least 5 days. ..
Li S, Jia Z, Chen X, Geng X, Sun J. Identification and characterization of the cDNAs encoding the two subunits of Chinese mitten crab (Eriocheir sinensis) calcineurin: their implications in stress and immune response. Fish Shellfish Immunol. 2015;43:91-102 pubmed publisher
..sinensis haemocytes. Together our observations suggest that EsCN, the important downstream effector of CaM-mediated signalling pathway(s), may possess vital roles in stress and immune response in the Chinese mitten crab. ..
Li S, Peng W, Chen X, Geng X, Sun J. Identification and characterization of nascent polypeptide-associated complex alpha from Chinese mitten crab (Eriocheir sinensis): A novel stress and immune response gene in crustaceans. Fish Shellfish Immunol. 2016;48:54-61 pubmed publisher
..Taken together, our findings for the first time show that EsNACA is an inducible gene involved in stress and immune response in crustaceans. ..
Li S, Chen X, Hao G, Geng X, Zhan W, Sun J. Identification and characterization of a novel NOD-like receptor family CARD domain containing 3 gene in response to extracellular ATP stimulation and its role in regulating LPS-induced innate immune response in Japanese flounder (Paralichthys olivac. Fish Shellfish Immunol. 2016;50:79-90 pubmed publisher
Li S, Chen X, Peng W, Hao G, Geng X, Zhan W, et al
. Cloning and characterization of apoptosis-associated speck-like protein containing a CARD domain (ASC) gene from Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2016;54:294-301 pubmed publisher
..Together, these findings addressed the involvement of PoASC in TLR and extracellular ATP-mediated innate immune signaling in the Japanese flounders. ..
Li S, Hao G, Xu Y, Wang N, Li J, Geng X, et al
. Functional characterization of purinergic P2Y2 and P2Y12 receptors involved in Japanese flounder (Paralichthys olivaceus) innate immune responses. Fish Shellfish Immunol. 2018;75:208-215 pubmed publisher
..Our findings have also addressed the importance of extracellular ATP and its metabolites in fish innate immune responses. ..
Li S, Chen X, Geng X, Zhan W, Sun J. Identification and expression analysis of nascent polypeptide-associated complex alpha gene in response to immune challenges in Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2015;46:261-7 pubmed publisher
..Taken together, our findings indicate that an immune response gene, poNACA, involved in innate immune regulation in P. olivaceus has been identified. ..
Li S, Chen X, Li X, Geng X, Lin R, Li M, et al
. Molecular characterization of purinergic receptor P2X4 involved in Japanese flounder (Paralichthys olivaceus) innate immune response and its interaction with ATP release channel Pannexin1. Fish Shellfish Immunol. 2015;47:100-9 pubmed publisher
..From a comparative immunological point of view, our results have provided new evidence for the involvement of extracellular ATP-gated P2XRs in fish innate immunity. ..