Hongliang Sun

Summary

Publications

  1. pmc Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesis
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 647, Rochester, NY 14642, USA
    Stem Cell Res 9:77-86. 2012
  2. pmc Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 647, Rochester, NY 14642 8647, United States
    Mutat Res 718:38-43. 2011
  3. doi request reprint Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model
    Yuhchyau Chen
    Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Health Phys 98:218-27. 2010
  4. pmc Gamma-radiation induces micronucleated reticulocytes in 3D bone marrow bioreactors in vitro
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, United States
    Mutat Res 680:49-55. 2009
  5. pmc Long-term immunologically competent human peripheral lymphoid tissue cultures in a 3D bioreactor
    Igor Kuzin
    Department of Medicine, University of Rochester School of Medicine and Dentistry, URMC 695, 601 Elmwood Ave, Rochester, New York 14642, USA
    Biotechnol Bioeng 108:1430-40. 2011
  6. pmc Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry
    Stephen D Dertinger
    Litron Laboratories, Rochester, NY 14623, USA
    Mutat Res 634:119-25. 2007

Collaborators

Detail Information

Publications6

  1. pmc Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesis
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 647, Rochester, NY 14642, USA
    Stem Cell Res 9:77-86. 2012
    ..Eltrombopag differed somewhat from rhTPO in the signal transduction pathways by favoring earlier HSC/HPC populations...
  2. pmc Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 647, Rochester, NY 14642 8647, United States
    Mutat Res 718:38-43. 2011
    ....
  3. doi request reprint Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model
    Yuhchyau Chen
    Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Health Phys 98:218-27. 2010
    ..In mice, the dose range of detection is useful up to 1 Gy (C57Bl/6) and 2 Gy (C3H) but not reliable beyond these dose limits. The utilization of this automated analysis for human radiation biodosimetry is currently under investigation...
  4. pmc Gamma-radiation induces micronucleated reticulocytes in 3D bone marrow bioreactors in vitro
    Hongliang Sun
    Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, United States
    Mutat Res 680:49-55. 2009
    ..5-2.0 Gy. The MN-RET response showed a downtrend beyond 2 Gy. Our data suggest that bone marrow culture in the 3D bioreactor may be a useful organ culture system for the investigation of radiation genotoxic effect in vitro...
  5. pmc Long-term immunologically competent human peripheral lymphoid tissue cultures in a 3D bioreactor
    Igor Kuzin
    Department of Medicine, University of Rochester School of Medicine and Dentistry, URMC 695, 601 Elmwood Ave, Rochester, New York 14642, USA
    Biotechnol Bioeng 108:1430-40. 2011
    ..Thus the three-dimensional tonsil bioreactor culture system may serve as a useful model of PLOs by recapitulating their structural organization and function ex vivo...
  6. pmc Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry
    Stephen D Dertinger
    Litron Laboratories, Rochester, NY 14623, USA
    Mutat Res 634:119-25. 2007
    ....