Christoph Sucker

Summary

Publications

  1. ncbi request reprint Rotation thromboelastography for the detection and characterization of lipoteichoid acid-induced activation of haemostasis in an in vitro sepsis model
    C Sucker
    Department of Haemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Perfusion 28:146-51. 2013
  2. doi request reprint [Spontaneous hematoma and hip pain in a 65-year old patient]
    C Sucker
    LaboMed Gerinnungszentrum Berlin, Tauentzienstr 7b c, 10789, Berlin, Deutschland
    Internist (Berl) 53:1234-9. 2012
  3. doi request reprint Rotation thromboelastography (ROTEM) parameters are influenced by age, gender, and oral contraception
    C Sucker
    LaboMed Coagulation Centre, Tauentzienstrasse 7, Berlin, Germany
    Perfusion 26:334-40. 2011
  4. ncbi request reprint Exercise-induced hemostatic alterations are detectable by rotation thrombelastography (ROTEM): A marathon study
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center Dusseldorf, Dusseldorf, Germany
    Clin Appl Thromb Hemost 16:543-8. 2010
  5. doi request reprint Causes, etiology and diagnosis of acquired von Willebrand disease: a prospective diagnostic workup to establish the most effective therapeutic strategies
    Christoph Sucker
    LaboMed Coagulation Center Berlin, Tauentzienstrasse 7 b c, Berlin, Germany
    Acta Haematol 121:177-82. 2009
  6. doi request reprint The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:283-8. 2009
  7. doi request reprint The G1691A mutation of the factor V gene (factor V Leiden) and the G20210A mutation of the prothrombin gene as risk factors in thrombotic microangiopathies
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:360-3. 2009
  8. ncbi request reprint Are prothrombotic variants of platelet glycoprotein receptor polymorphisms involved in the pathogenesis of thrombotic microangiopathies?
    Christoph Sucker
    Departments of Hemostasis and Transfusion Medicine Heinrich Heine University Medical Center, Moorenstrasse 5, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:402-7. 2009
  9. ncbi request reprint The homozygous leu variant of the factor XIII Val34Leu polymorphism as a risk factor for the manifestation of thrombotic microangiopathies
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:197-200. 2009
  10. ncbi request reprint Determination of von Willebrand factor activity: evaluation of the HaemosIL assay in comparison with established procedures
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Duesseldorf, Germany
    Clin Appl Thromb Hemost 12:305-10. 2006

Detail Information

Publications19

  1. ncbi request reprint Rotation thromboelastography for the detection and characterization of lipoteichoid acid-induced activation of haemostasis in an in vitro sepsis model
    C Sucker
    Department of Haemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Perfusion 28:146-51. 2013
    ..In gram-positive sepsis, lipoteichoic acid (LTA) can induce alterations of haemostasis, potentially leading to disseminated intravascular coagulation...
  2. doi request reprint [Spontaneous hematoma and hip pain in a 65-year old patient]
    C Sucker
    LaboMed Gerinnungszentrum Berlin, Tauentzienstr 7b c, 10789, Berlin, Deutschland
    Internist (Berl) 53:1234-9. 2012
    ..Impairment of plasmatic hemostasis leads to a severe bleeding tendency in individuals without a preexisting coagulation defect with considerable mortality. Pathophysiology, diagnostic work-up, and treatment are summarized and discussed...
  3. doi request reprint Rotation thromboelastography (ROTEM) parameters are influenced by age, gender, and oral contraception
    C Sucker
    LaboMed Coagulation Centre, Tauentzienstrasse 7, Berlin, Germany
    Perfusion 26:334-40. 2011
    ..Thus, adjustment for age, gender, and oral contraception is required when ROTEM is used to screen for distinct abnormalities of haemostasis...
  4. ncbi request reprint Exercise-induced hemostatic alterations are detectable by rotation thrombelastography (ROTEM): A marathon study
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center Dusseldorf, Dusseldorf, Germany
    Clin Appl Thromb Hemost 16:543-8. 2010
    ..This might help to explain interindividual differences in exercise-induced alterations of hemostasis...
  5. doi request reprint Causes, etiology and diagnosis of acquired von Willebrand disease: a prospective diagnostic workup to establish the most effective therapeutic strategies
    Christoph Sucker
    LaboMed Coagulation Center Berlin, Tauentzienstrasse 7 b c, Berlin, Germany
    Acta Haematol 121:177-82. 2009
    ..Since the optimal treatment strategy has not yet been defined for aVWD of different etiology, controlled multicenter trials aiming at the development of standardized treatment protocols are urgently needed...
  6. doi request reprint The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:283-8. 2009
    ..The 677 TT genotype of this polymorphism appears to be a risk factor for manifestation of these rare thrombotic disorders, possibly explained by endothelial activation and increased oxidative stress...
  7. doi request reprint The G1691A mutation of the factor V gene (factor V Leiden) and the G20210A mutation of the prothrombin gene as risk factors in thrombotic microangiopathies
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:360-3. 2009
    ..Thus, screening for these mutations does not allow the identification of individuals at increased risk for these rare thrombotic disorders...
  8. ncbi request reprint Are prothrombotic variants of platelet glycoprotein receptor polymorphisms involved in the pathogenesis of thrombotic microangiopathies?
    Christoph Sucker
    Departments of Hemostasis and Transfusion Medicine Heinrich Heine University Medical Center, Moorenstrasse 5, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:402-7. 2009
    ..Along with this observation, screening for respective platelet-receptor polymorphisms does not appear to contribute to risk stratification of affected patients...
  9. ncbi request reprint The homozygous leu variant of the factor XIII Val34Leu polymorphism as a risk factor for the manifestation of thrombotic microangiopathies
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:197-200. 2009
    ..Decreased fibrinolysis in the presence of this genetic variant provides a plausible explanation for this association...
  10. ncbi request reprint Determination of von Willebrand factor activity: evaluation of the HaemosIL assay in comparison with established procedures
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Duesseldorf, Germany
    Clin Appl Thromb Hemost 12:305-10. 2006
    ..Since the assay does not predict the absence of high-molecular-weight multimers, multimeric analysis remains the procedure of choice for the differentiation of functional defects...
  11. doi request reprint Use of recombinant factor VIIa in inherited and acquired von Willebrand disease
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Dusseldorf, Germany
    Clin Appl Thromb Hemost 15:27-31. 2009
    ..Controlled clinical studies are necessary to define the use of rFVIIa in this clinical setting...
  12. ncbi request reprint Citrate plasma levels in patients under regional anticoagulation in continuous venovenous hemofiltration
    Gerd R Hetzel
    Department of Nephrology, Heinrich Heine University Medical Center, Duesseldorf, Germany
    Am J Kidney Dis 48:806-11. 2006
    ..However, none of these parameters has been correlated with plasma citrate levels in critically ill patients...
  13. ncbi request reprint Association of genotypes of thrombin-activatable fibrinolysis inhibitors with thrombotic microangiopathies--a pilot study
    Christoph Sucker
    Department of Haemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Moorenstrasse 5, 40221 Duesseldorf, Germany
    Nephrol Dial Transplant 22:1347-50. 2007
    ..Although recent research has elucidated the pathogenesis of these rare thrombotic disorders to some extent, the determinants contributing to the manifestation remain rather unclear in the majority of affected patients...
  14. ncbi request reprint Fatal bleeding due to a heparin-like anticoagulant in a 37-year-old woman suffering from systemic mastocytosis
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Germany
    Clin Appl Thromb Hemost 14:360-4. 2008
    ..The case illustrates the clinical presentation and diagnosis of heparin-like anticoagulants. Etiology, pathophysiology, and therapeutic options are discussed...
  15. ncbi request reprint Recombinant factor VIIa for the prophylaxis of perioperative hemorrhage in a patient with congenital factor XI deficiency undergoing brain tumor neurosurgery
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Moorenstrasse 5, Dusseldorf, Germany
    Clin Appl Thromb Hemost 14:472-5. 2008
    ..In this setting, off-label use of recombinant activated factor VII appears to be a promising alternative for patients suffering from this rare hemostatic defect with hitherto limited therapeutic options...
  16. ncbi request reprint Monitoring oral anticoagulation may require determination of single coagulation factor activities in patients with antiphospholipid syndrome
    Christoph Sucker
    Department of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, Duesseldorf, Germany
    J Rheumatol 33:1881-2. 2006
    ..The case illustrates that monitoring of oral anticoagulation may require determination of single coagulation factor activities in selected patients with APS...
  17. ncbi request reprint No evidence for increased intraoperative bleeding in aortic-valve stenosis: a comparative analysis of haemotherapy in 136 patients undergoing aortic-valve replacement
    Christoph Sucker
    LaboMed Coagulation Centre, Berlin, Germany
    Acta Cardiol 65:675-9. 2010
    ..Consequently, highest-molecular weight multimers of the von Willebrand factor are degraded through a von Willebrand factor specific protease leading to impaired platelet-related haemostasis...
  18. ncbi request reprint Amyloidosis and bleeding: pathophysiology, diagnosis, and therapy
    Christoph Sucker
    Department of Hemostasis, Heinrich Heine University Medical Center, Duesseldorf, Germany
    Am J Kidney Dis 47:947-55. 2006
    ..In this review, we focus on bleeding risks in patients with amyloid diseases. Current concepts with regard to pathophysiology, diagnosis, and treatment are summarized and discussed...
  19. pmc Indicators of acute and persistent renal damage in adult thrombotic microangiopathy
    Firuseh Dierkes
    Department of Nephrology, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
    PLoS ONE 7:e30886. 2012
    ..Clinical presentation is highly variable and prognostic factors for clinical course and outcome are not well established...