J Michael Straughn

Summary

Publications

  1. ncbi request reprint Conservative management of stage I endometrial carcinoma after surgical staging
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Gynecol Oncol 84:194-200. 2002
  2. ncbi request reprint The use of adjuvant radiation therapy in patients with intermediate-risk Stages IC and II uterine corpus cancer: a patient care evaluation study from the American College of Surgeons National Cancer Data Base
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama, Birmingham, AL 35249, USA
    Gynecol Oncol 99:530-5. 2005
  3. ncbi request reprint Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama at Birmingham, 619 19th Street South, OHB Room 538, Birmingham, AL 35249, USA
    Gynecol Oncol 101:46-54. 2006
  4. ncbi request reprint Stage IC adenocarcinoma of the endometrium: survival comparisons of surgically staged patients with and without adjuvant radiation therapy
    J Michael Straughn
    University of Alabama at Birmingham, 35249, USA
    Gynecol Oncol 89:295-300. 2003
  5. ncbi request reprint Pelvic umbrella pack for refractory obstetric hemorrhage secondary to posterior uterine rupture
    Rebecca J Howard
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Obstet Gynecol 100:1061-3. 2002
  6. ncbi request reprint Cost-effectiveness analysis of strategies for the surgical management of grade 1 endometrial adenocarcinoma
    David E Cohn
    Division of Gynecologic Oncology, Ohio State University College of Medicine, Columbus, Ohio, USA
    Obstet Gynecol 109:1388-95. 2007
  7. ncbi request reprint Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model
    Peter J Frederick
    Division of Gynecologic Oncology, Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Gynecol Cancer 19:814-9. 2009
  8. ncbi request reprint Patterns of failure for conservatively managed surgical stage I uterine carcinosarcoma: implications for adjuvant therapy
    Charles A Leath
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Gynecol Cancer 19:888-91. 2009
  9. ncbi request reprint The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer
    Rodney P Rocconi
    Division of Gynecologic Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA
    Gynecol Oncol 114:242-5. 2009
  10. ncbi request reprint Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer
    Rebecca C Arend
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA Electronic address
    Gynecol Oncol 134:112-20. 2014

Collaborators

Detail Information

Publications76

  1. ncbi request reprint Conservative management of stage I endometrial carcinoma after surgical staging
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Gynecol Oncol 84:194-200. 2002
    ..The aim of this study was to determine the outcomes of Stage I endometrial carcinoma patients who are managed without adjuvant radiation after comprehensive surgical staging...
  2. ncbi request reprint The use of adjuvant radiation therapy in patients with intermediate-risk Stages IC and II uterine corpus cancer: a patient care evaluation study from the American College of Surgeons National Cancer Data Base
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama, Birmingham, AL 35249, USA
    Gynecol Oncol 99:530-5. 2005
    ..To determine the outcomes of patients with intermediate-risk Stages IC and II uterine corpus cancer treated with surgery alone or surgery followed by radiation therapy...
  3. ncbi request reprint Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model
    J Michael Straughn
    Division of Gynecologic Oncology, University of Alabama at Birmingham, 619 19th Street South, OHB Room 538, Birmingham, AL 35249, USA
    Gynecol Oncol 101:46-54. 2006
    ..We sought to determine the therapeutic potential of TRA-8 (anti-DR5 monoclonal antibody) in combination with chemotherapy and radiation therapy in a cervical cancer model...
  4. ncbi request reprint Stage IC adenocarcinoma of the endometrium: survival comparisons of surgically staged patients with and without adjuvant radiation therapy
    J Michael Straughn
    University of Alabama at Birmingham, 35249, USA
    Gynecol Oncol 89:295-300. 2003
    ..The goal of this study was to determine the outcomes of stage IC endometrial carcinoma patients who are managed with and without adjuvant radiation therapy after comprehensive surgical staging...
  5. ncbi request reprint Pelvic umbrella pack for refractory obstetric hemorrhage secondary to posterior uterine rupture
    Rebecca J Howard
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Obstet Gynecol 100:1061-3. 2002
    ..Pelvic hemorrhage continues to be a serious complication of pregnancy and can lead to significant maternal morbidity. The pelvic umbrella pack is a useful alternative to control pelvic bleeding when standard measures fail...
  6. ncbi request reprint Cost-effectiveness analysis of strategies for the surgical management of grade 1 endometrial adenocarcinoma
    David E Cohn
    Division of Gynecologic Oncology, Ohio State University College of Medicine, Columbus, Ohio, USA
    Obstet Gynecol 109:1388-95. 2007
    ..To estimate the costs and outcomes of various strategies used for the management of grade 1 endometrial cancer...
  7. ncbi request reprint Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model
    Peter J Frederick
    Division of Gynecologic Oncology, Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Gynecol Cancer 19:814-9. 2009
    ..To investigate the cytotoxicity of TRA-8, an antibody that specifically binds death receptor 5, alone and in combination with chemotherapy, using an ex vivo human ovarian cancer model...
  8. ncbi request reprint Patterns of failure for conservatively managed surgical stage I uterine carcinosarcoma: implications for adjuvant therapy
    Charles A Leath
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Gynecol Cancer 19:888-91. 2009
    ..Because most patients will recur distantly, systemic chemotherapy should be considered for patients with early stage uterine carcinosarcoma...
  9. ncbi request reprint The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer
    Rodney P Rocconi
    Division of Gynecologic Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA
    Gynecol Oncol 114:242-5. 2009
    ..To determine if the timing of normalization of CA-125 levels during primary chemotherapy for epithelial ovarian cancer (EOC) could predict survival...
  10. ncbi request reprint Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer
    Rebecca C Arend
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA Electronic address
    Gynecol Oncol 134:112-20. 2014
    ..Targeting the Wnt/β-catenin pathway led to decreased cellular proliferation and increased cell death. These findings warrant further research of this drug and other niclosamide analogs as a treatment option for ovarian cancer...
  11. ncbi request reprint Bowel resection at the time of primary debulking for epithelial ovarian carcinoma: outcomes in patients treated with platinum and taxane-based chemotherapy
    Jacob M Estes
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama Birmingham, 619 19th Street South, Birmingham, AL 35249 7333, USA
    J Am Coll Surg 203:527-32. 2006
    ..Our goal was to determine the morbidity, disease-free survival, and overall survival of patients with bowel resection at primary cytoreductive surgery for advanced epithelial ovarian carcinoma in the era of platinum and taxane chemotherapy...
  12. ncbi request reprint Diagnostic loop electrosurgical excisional procedure for discrepancy: do preoperative factors predict presence of significant cervical intraepithelial neoplasia?
    Kellie S Matthews
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35249 7333, USA
    J Low Genit Tract Dis 11:69-72. 2007
    ..Our objective was to determine the incidence of cervical intraepithelial neoplasia (CIN) 2,3 and patient factors that increase the likelihood of detecting CIN 2,3...
  13. ncbi request reprint Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model
    James E Kendrick
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 108:591-7. 2008
    ..To investigate the cytotoxicity of TRA-8, an antibody that specifically binds death receptor 5 (DR5), alone and in combination with cisplatin, using an ex vivo human cervical cancer model...
  14. ncbi request reprint Role of chemotherapy for patients with recurrent platinum-resistant advanced epithelial ovarian cancer: A cost-effectiveness analysis
    Rodney P Rocconi
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Cancer 107:536-43. 2006
    ..Therefore, the objective in the current study was to assess the cost-effectiveness of salvage chemotherapy for patients with platinum-resistant epithelial ovarian cancer (EOC)...
  15. ncbi request reprint Prognostic significance of the relative dose intensity of chemotherapy in primary treatment of epithelial ovarian cancer
    Janelle M Fauci
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecology Oncology, Birmingham, AL 35249, USA
    Gynecol Oncol 122:532-5. 2011
    ..Relative dose intensity (RDI) is the ratio of delivered dose intensity of chemotherapy to standard dose intensity. In this study, we sought to determine the prognostic significance of RDI in patients with epithelial ovarian cancer (EOC)...
  16. doi request reprint Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma
    Elizabeth H Kerr
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA
    Ann Surg Oncol 20:3059-65. 2013
    ....
  17. doi request reprint Perioperative morbidity and mortality in octogenarians with ovarian cancer
    Christen L Walters
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, AL 35233, USA
    Int J Gynecol Cancer 23:1006-9. 2013
    ..We compared perioperative morbidity and mortality of octogenarians compared with younger patients undergoing surgical cytoreduction...
  18. ncbi request reprint Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model
    Jacob M Estes
    Division of Gynecologic Oncology, The University of Alabama at Birmingham, 619 19th Street South, OHB 538, Birmingham, AL 35249, USA
    Gynecol Oncol 105:291-8. 2007
    ....
  19. ncbi request reprint The safety and efficacy of day 1 versus day 2 administration of pegfilgrastim in patients receiving myelosuppressive chemotherapy for gynecologic malignancies
    Jenny M Whitworth
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 618 South 19th Street, Old Hillman Building 538, Birmingham, AL 35233, USA
    Gynecol Oncol 112:601-4. 2009
    ..We sought to compare the safety and efficacy of day 1 pegfilgrastim administration to day 2 administration in patients with gynecologic malignancies...
  20. ncbi request reprint Pegylated liposomal doxorubicin consolidation therapy after platinum/paclitaxel-based chemotherapy for suboptimally debulked, advanced-stage epithelial ovarian cancer patients
    Rodney P Rocconi
    University of Alabama at Birmingham, 35233, USA
    Oncologist 11:336-41. 2006
    ....
  21. ncbi request reprint The impact of aborted radical hysterectomy in patients with cervical carcinoma
    Charles A Leath
    Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Alabama at Birmingham, Birmingham, AL 35249 7333, USA
    Gynecol Oncol 95:204-7. 2004
    ..To determine the impact of an aborted radical hysterectomy on morbidity and overall survival in patients undergoing surgical treatment for early stage cervical carcinoma...
  22. doi request reprint Lipoxygenase pathway receptor expression in ovarian cancer
    Rodney P Rocconi
    Department of Obstetrics and Gynecology, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama 36607, USA
    Reprod Sci 15:321-6. 2008
    ..To determine the expression of lipoxygenase (LOX) pathway receptors in ovarian cancer as a potential target for anti-LOX-based therapy...
  23. ncbi request reprint A cost-effectiveness analysis of chemotherapy for patients with recurrent platinum-sensitive epithelial ovarian cancer
    Ashley S Case
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, USA
    Gynecol Oncol 105:223-7. 2007
    ..Therefore, our goal was to assess the effectiveness and medical costs of chemotherapy for platinum-sensitive patients with advanced EOC...
  24. pmc The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells
    Jenny M Whitworth
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
    Gynecol Oncol 125:226-30. 2012
    ..We evaluated these novel retinoids in combination with chemotherapy against ovarian cancer stem cells (CSCs) in vitro and in an ex vivo model...
  25. doi request reprint The effect of obesity on survival in patients with ovarian cancer
    Kellie S Matthews
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Gynecol Oncol 112:389-93. 2009
    ..We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival...
  26. ncbi request reprint Management strategies for stage IB2 cervical cancer: a cost-effectiveness analysis
    Rodney P Rocconi
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 618 South 19th Street, Old Hillman Building Room 538, Birmingham, AL 35233, USA
    Gynecol Oncol 97:387-94. 2005
    ..To assess the potential effectiveness and medical costs of three common strategies to manage Stage IB2 squamous cell carcinoma of the cervix (CXCA)...
  27. doi request reprint Completed versus aborted radical hysterectomy for node-positive stage IB cervical cancer in the modern era of chemoradiation therapy
    Angela J Ziebarth
    University of Alabama at Birmingham, Birmingham, AL, USA
    Gynecol Oncol 126:69-72. 2012
    ..Debate continues about optimal management of patients with node-positive stage I cervical cancer. Our objective was to determine if patient outcomes are affected by radical hysterectomy in the modern era of adjuvant chemoradiation...
  28. ncbi request reprint Immunohistochemical evaluation of the c-kit proto-oncogene in sarcomas of the uterus: a case series
    Charles A Leath
    Division of Gynecologic Oncology, University of Alabama at Birmingham, USA
    J Reprod Med 49:71-5. 2004
    ..To evaluate the incidence of c-kit expression in uterine sarcomas...
  29. ncbi request reprint Outcomes of Stage I/II vulvar cancer patients after negative superficial inguinal lymphadenectomy
    Tyler O Kirby
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, OHB 538, 619 19th Street South, Birmingham, AL 35249 7333, USA
    Gynecol Oncol 98:309-12. 2005
    ..To investigate the patterns of recurrence associated with superficial inguinal lymphadenectomy (SupIL) and vulvectomy for patients with Stage I/II vulvar cancer...
  30. ncbi request reprint The management of cervical intraepithelial neoplasia during pregnancy: is colposcopy necessary?
    Luisa A Wetta
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Low Genit Tract Dis 13:182-5. 2009
    ..Therefore, we sought to determine the incidence of cervical intraepithelial neoplasia (CIN) 2,3 in pregnant patients referred to a university colposcopy clinic...
  31. ncbi request reprint Uterine papillary serous carcinoma: comparisons of outcomes in surgical Stage I patients with and without adjuvant therapy
    Warner K Huh
    University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 91:470-5. 2003
    ..Our aim was to determine the outcomes of Stage I uterine papillary serous carcinoma (UPSC) patients with and without adjuvant therapy after comprehensive surgical staging...
  32. ncbi request reprint A prospective evaluation of "see and treat" in women with HSIL Pap smear results: is this an appropriate strategy?
    T Michael Numnum
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35294 7333, USA
    J Low Genit Tract Dis 9:2-6. 2005
    ..The objective of this study was to determine the incidence of CIN 2 and CIN 3 in patients with an HSIL (CIN 2) Pap smear using a see-and-treat protocol...
  33. pmc Lynch syndrome in women less than 50 years of age with endometrial cancer
    Kellie S Matthews
    Division of Gynecologic Oncology and the Division of Anatomic Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Obstet Gynecol 111:1161-6. 2008
    ..To estimate the frequency of mismatch repair deficiencies associated with hereditary nonpolyposis colorectal cancer, or Lynch syndrome, in women less than age 50 with endometrial cancer...
  34. ncbi request reprint Conservative management of postoperative Fever in gynecologic patients undergoing major abdominal or vaginal operations
    James E Kendrick
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, AL 35249 7333, USA
    J Am Coll Surg 207:393-7. 2008
    ..To develop a standardized protocol for management of postoperative fever in gynecology patients to decrease unnecessary diagnostic workups and empiric use of antibiotics...
  35. doi request reprint Monoclonal antibody-based immunotherapy of ovarian cancer: targeting ovarian cancer cells with the B7-H3-specific mAb 376.96
    Janelle M Fauci
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, USA Electronic address
    Gynecol Oncol 132:203-10. 2014
    ..96, which recognizes a B7-H3 epitope expressed on ovarian carcinoma cells (OCCs), in combination with the tyrosine kinase inhibitor Sunitinib and chemotherapy on chemosensitive and chemoresistant cells and CICs...
  36. ncbi request reprint Comparison of operative risks associated with radical hysterectomy in pregnant and nonpregnant women
    Charles A Leath
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama School of Medicine, 1700 6th Avenue South, Room 10250, Birmingham, AL 35249, USA
    J Reprod Med 58:279-84. 2013
    ..To compare the operative data and complications of radical hysterectomy performed on pregnant women versus nonpregnant women...
  37. doi request reprint Double prophylaxis for deep venous thrombosis in patients with gynecologic oncology who are undergoing laparotomy: does preoperative anticoagulation matter?
    Jenny M Whitworth
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
    Int J Gynecol Cancer 21:1131-4. 2011
    ..We sought to determine the effectiveness and adverse effects of a preoperative dose of anticoagulation in patients with gynecologic oncology...
  38. ncbi request reprint The risk of gastrointestinal perforation and/or fistula in patients with recurrent ovarian cancer receiving bevacizumab compared to standard chemotherapy: a retrospective cohort study
    Gregory P Sfakianos
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7333, USA
    Gynecol Oncol 114:424-6. 2009
    ..To determine the rate of gastrointestinal perforation and/or fistula in patients with recurrent ovarian cancer treated with and without bevacizumab...
  39. ncbi request reprint Unilateral cervical cancer in a patient with cervix duplex
    Kristopher J Kimball
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 103:346-8. 2006
    ..Although uterine anomalies are uncommon, gynecologists must be aware of the anatomical challenges that may be encountered from these anomalies. Cervical cancer in the context of a mullerian lateral fusion defect is rare...
  40. ncbi request reprint A prospective blinded evaluation of the accuracy of frozen section for the surgical management of endometrial cancer
    Ashley S Case
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama
    Obstet Gynecol 108:1375-9. 2006
    ..To prospectively evaluate in a blinded fashion the accuracy of frozen section in endometrial cancer...
  41. ncbi request reprint The role of radical parametrectomy in the treatment of occult cervical carcinoma after extrafascial hysterectomy
    Charles A Leath
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35249 7333, USA
    Gynecol Oncol 92:215-9. 2004
    ..To assess the morbidity and efficacy of radical parametrectomy (RP) performed following extrafascial hysterectomy in patients with occult cervical carcinoma...
  42. ncbi request reprint Lynch syndrome screening strategies among newly diagnosed endometrial cancer patients
    Kimberly Resnick
    Division of Gynecologic Oncology, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, OH 43210, USA
    Obstet Gynecol 114:530-6. 2009
    ..To estimate the cost-effectiveness of screening strategies for Lynch syndrome among newly diagnosed endometrial cancer patients...
  43. ncbi request reprint Fertility sparing therapy in a patient with placental site trophoblastic tumor: a case report
    T Michael Numnum
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, 618 19th Street South, OHB 538, Birmingham, AL 35249, USA
    Gynecol Oncol 103:1141-3. 2006
    ..Patients with localized disease are usually managed with hysterectomy...
  44. doi request reprint Anti-tumor activity of an anti-DR5 monoclonal antibody, TRA-8, in combination with taxane/platinum-based chemotherapy in an ovarian cancer model
    Kerri S Bevis
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 121:193-9. 2011
    ..We evaluated the efficacy of TRA-8, an agonistic antibody to DR5, combined with docetaxel and carboplatin in vitro in an intraperitoneal (IP) ovarian cancer model...
  45. ncbi request reprint Recurrence of endometrial adenocarcinoma in a prior Bartholin's cyst marsupialization incision
    Kimberly Ray
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249 7333, USA
    Gynecol Oncol 103:749-51. 2006
    ..Endometrial cancer recurrences in surgical incisions are rare and thought to be due to seeding of the area with microscopic disease at the time of original surgery...
  46. doi request reprint Preclinical studies and clinical utilization of monoclonal antibodies in epithelial ovarian cancer
    Peter J Frederick
    Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 113:384-90. 2009
    ..To present an overview of selected monoclonal antibodies (mAbs) that have been studied in epithelial ovarian cancer with a focus on combination treatment with conventional chemotherapy...
  47. ncbi request reprint Reasons for failure to deliver National Comprehensive Cancer Network (NCCN)-adherent care in the treatment of epithelial ovarian cancer at an NCCN cancer center
    Britt K Erickson
    University of Alabama at Birmingham, Division of Gynecologic Oncology, USA Electronic address
    Gynecol Oncol 133:142-6. 2014
    ..The objective of this study was to determine the reasons for failure to deliver NCCN-adherent care at an NCCN cancer center serving a diverse racial and socioeconomic population...
  48. pmc Management of complex pelvic masses using a multivariate index assay: a decision analysis
    Kenneth H Kim
    Division of Gynecologic Oncology, University of Alabama at Birmingham, USA
    Gynecol Oncol 126:364-8. 2012
    ..To develop a cost-minimization analysis of a multivariate index assay (MIA) used for women with complex pelvic masses...
  49. doi request reprint Robotic surgery in gynecologic oncology fellowship programs in the USA: a survey of fellows and fellowship directors
    Gregory P Sfakianos
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35294 7333, USA
    Int J Med Robot 6:405-12. 2010
    ..In order to understand how robotic surgery impacts gynecologic oncology fellowship training and surgical practices, a survey of fellows and fellowship directors was conducted...
  50. ncbi request reprint Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers
    James E Kendrick
    Division of Gynecologic Oncology, The University of Alabama at Birmingham, 619 19th Street South, OHB 538, Birmingham, AL 35249, USA
    Gynecol Oncol 106:614-21. 2007
    ..TRAIL-receptor-activating agents have demonstrated favorable in vitro and in vivo activity for the treatment of several malignancies including breast and gynecologic cancers...
  51. ncbi request reprint Efficacy and toxicity of the novel chemotherapeutic agent KW-2170 in recurrent epithelial ovarian cancer
    Jacob M Estes
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 618 South 19th Street, Old Hillman Building Room 538, Birmingham, AL 35233, USA
    Gynecol Oncol 102:338-42. 2006
    ..The objective of this study was to evaluate the activity and toxicity of this novel chemotherapeutic agent in patients with recurrent ovarian carcinoma...
  52. doi request reprint Impact of a weekly multidisciplinary tumor board conference on the management of women with gynecologic malignancies
    Heather O Greer
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street S, Birmingham, AL 35249, USA
    Int J Gynecol Cancer 20:1321-5. 2010
    ..The objective of this study was to evaluate the impact of a weekly tumor board conference on the management of patients with gynecologic malignancies...
  53. ncbi request reprint Predictors of outcomes for women with cervical carcinoma
    Charles A Leath
    Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Alabama at Birmingham, 619 19th Street South, OHB538, Birmingham, AL 35249 7333, USA
    Gynecol Oncol 99:432-6. 2005
    ..To determine the impact of race and other factors on the management and outcomes of women treated for cervical cancer in a rural state...
  54. ncbi request reprint Cervical intraepithelial neoplasia in adolescent women: incidence and treatment outcomes
    Ashley S Case
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obstet Gynecol 108:1369-74. 2006
    ..We sought to estimate the incidence of cervical intraepithelial neoplasia (CIN) and treatment outcomes in adolescents with abnormal cytology...
  55. doi request reprint Incidence of mechanical malfunction in low-profile subcutaneous implantable venous access devices in patients receiving chemotherapy for gynecologic malignancies
    Akila Subramaniam
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35223, USA
    Gynecol Oncol 123:54-7. 2011
    ..The purpose of this study was to investigate the incidence of mechanical complications associated with low-profile subcutaneous implantable venous access devices in gynecologic oncology patients...
  56. ncbi request reprint Early abdominal incision recurrence in a patient with stage I adenocarcinoma of the endometrium
    Chi Chiung Grace Chen
    Division of Gynecologic Oncology, University of Alabama, Birmingham, Alabama, USA
    Obstet Gynecol 104:1170-2. 2004
    ..Although recurrences have been reported at laparoscopic trochar sites, it is unusual to have a recurrence in the abdominal incision after laparotomy...
  57. ncbi request reprint Recurrent basosquamous cell carcinoma of the vulva
    Kristopher J Kimball
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, 534 19th Street S, Birmingham, AL 35249 73333 USA
    Gynecol Oncol 102:400-2. 2006
    ..Basosquamous cell carcinoma (BSC) of the vulva is a rare entity with interesting prognostic and therapeutic implications. Currently, there is no definitive treatment due to its low incidence...
  58. ncbi request reprint The role of comprehensive surgical staging in patients with endometrial cancer
    Peter J Frederick
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Birmingham, AL 35249 7333, USA
    Cancer Control 16:23-9. 2009
    ..Patients who undergo pelvic and para-aortic lymphadenectomy are more likely to be accurately staged and are less likely to receive adjuvant radiation therapy...
  59. doi request reprint Outcomes of patients with gynecologic malignancies undergoing video-assisted thoracoscopic surgery (VATS) and pleurodesis for malignant pleural effusion
    Jenny M Whitworth
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 1700 6th Avenue South, Birmingham, AL 35233, USA
    Gynecol Oncol 125:646-8. 2012
    ..We evaluated the indications and outcomes of patients with known gynecologic malignancies that underwent video-assisted thoracoscopic surgery (VATS) and pleurodesis for malignant pleural effusion...
  60. ncbi request reprint Complications of indwelling venous access devices in patients with gynecologic malignancies
    Jacob M Estes
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Gynecol Oncol 91:591-5. 2003
    ..The purpose of this study was to evaluate the complication rates associated with indwelling venous access devices in patients with gynecologic malignancies...
  61. ncbi request reprint Overcoming TRAIL resistance in ovarian carcinoma
    Kerri S Bevis
    Division of Gynecologic Oncology, University of Alabama at Birmingham, 176F RM10250, 619 19th Street South, Birmingham, AL 35249, USA
    Gynecol Oncol 119:157-63. 2010
    ..Despite initially promising results from early TRAIL studies in ovarian cancer, reports of significant TRAIL resistance soon followed. The current study reviews strategies to overcome TRAIL resistance in ovarian cancer...
  62. ncbi request reprint A comparison of hand-assisted laparoscopy and conventional laparotomy for the surgical evaluation of pelvic masses
    Whitney A Spannuth
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 619 19th Street South, Old Hillman Building Room 538, Birmingham, AL 35294 7333, USA
    Gynecol Oncol 99:443-6. 2005
    ..Our goal was to compare HALS to conventional laparotomy for pelvic masses in gynecologic patients...
  63. ncbi request reprint Expression of sperm protein 17 (Sp17) in ovarian cancer
    J Michael Straughn
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Alabama, Birmingham, AL 35294, USA
    Int J Cancer 108:805-11. 2004
    ..Because Sp17 is immunogenic, it may represent a novel target for immunotherapeutic interventions for ovarian cancer patients...
  64. ncbi request reprint Occult choriocarcinoma discovered by positron emission tomography/computed tomography imaging following a successful pregnancy
    T Michael Numnum
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street South, OHB 340, Birmingham, AL 35294, USA
    Gynecol Oncol 97:713-5. 2005
    ..Recently, there have been reports of PET scans used in patients with Gestational Trophoblastic Disease (GTD)...
  65. ncbi request reprint Management strategies for abnormal early pregnancy: a cost-effectiveness analysis
    Rodney P Rocconi
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham 35233, USA
    J Reprod Med 50:486-90. 2005
    ..To assess the potential effectiveness and costs of 4 commonly used strategies to manage abnormal early pregnancies (AEPs)...
  66. doi request reprint Chemotherapy for advanced and recurrent cervical carcinoma: results from cooperative group trials
    Charles A Leath
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA
    Gynecol Oncol 129:251-7. 2013
    ..To review the clinical trial experience with chemotherapy for patients with primary Stage IVB, persistent and recurrent cervical cancer...
  67. doi request reprint A review of B7-H3 and B7-H4 immune molecules and their role in ovarian cancer
    Janelle M Fauci
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, USA
    Gynecol Oncol 127:420-5. 2012
    ....
  68. ncbi request reprint The use of retinoids in ovarian cancer: a review of the literature
    Jenny M Whitworth
    Departments of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Int J Gynecol Cancer 22:191-8. 2012
    ..In this article, we reviewed preclinical studies and clinical trials conducted using retinoids in ovarian cancer...
  69. pmc Life-space assessment in urogynecology and gynecological oncology surgery patients: a measure of perioperative mobility and function
    Chere M L Stewart
    Division of Women s Reproductive Healthcare, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Am Geriatr Soc 57:2263-8. 2009
    ..To assess the effect of gynecological surgery on mobility and functional status in women aged 60 and older using Life-Space Assessment (LSA)...
  70. ncbi request reprint Complete uterine necrosis following chemoradiation for advanced cervical cancer: a case report
    Kellie S Matthews
    University of Alabama at Birmingham, Division of Gynecologic Oncology, Birmingham, AL 35249, USA
    Gynecol Oncol 106:265-7. 2007
    ..Although generally transient, complications of radiation therapy can become severe and require further intervention. Uterine necrosis is uncommon and the management can be complex...
  71. ncbi request reprint Two cases of non-Hodgkin's lymphoma presenting as primary gynecologic malignancies
    James E Kendrick
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 618 South 19th Street, Birmingham, AL 35233, USA
    Gynecol Oncol 98:490-2. 2005
    ..Non-Hodgkin's lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively...
  72. ncbi request reprint Uterine leiomyosarcoma metastatic to the thyroid
    Charles A Leath
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7333, USA
    Obstet Gynecol 100:1122-4. 2002
    ..Uterine leiomyosarcoma is an aggressive tumor that has a propensity for distant metastasis. Distant sites of spread include the lung, liver, brain, and bone...
  73. ncbi request reprint A cost-effectiveness analysis of management strategies for cervical intraepithelial neoplasia grades 2 and 3
    Marc J Kleinberg
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street S, OHB Room 340, Birmingham, AL 35249, USA
    Am J Obstet Gynecol 188:1186-8. 2003
    ..This study was performed to compare the cost-effectiveness of strategies for the management of cervical intraepithelial neoplasia, grades 2 and 3 (CIN 2 and CIN 3)...
  74. ncbi request reprint Use of a fascial prosthesis for management of abdominal compartment syndrome secondary to obstetric hemorrhage
    James E Kendrick
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Obstet Gynecol 107:493-6. 2006
    ..Massive obstetric hemorrhage can be catastrophic, with considerable maternal morbidity and mortality...
  75. ncbi request reprint Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids
    John T Lam
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Cancer Gene Ther 10:377-87. 2003
    ..Therefore, spheroids provide a method to sustain purified unpassaged primary ovarian cancer cells for extended periods and to allow evaluation of replicative viruses in a three-dimensional model...
  76. pmc Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects
    Chih Wen Tseng
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Vaccine 26:4314-9. 2008
    ..Our findings serve as an important foundation for future clinical translation...