Esther T Stoeckli

Summary

Publications

  1. doi request reprint What does the developing brain tell us about neural diseases?
    Esther T Stoeckli
    Institute of Molecular Life Sciences and Neuroscience, University of Zurich, Zurich, Switzerland
    Eur J Neurosci 35:1811-7. 2012
  2. pmc Rostral growth of commissural axons requires the cell adhesion molecule MDGA2
    Pascal Joset
    Brain Research Institute, University of Zurich and Swiss Federal Institute of Technology ETH, Department of Biology, 8057 Zurich, Switzerland
    Neural Dev 6:22. 2011
  3. pmc Neural circuit formation in the cerebellum is controlled by cell adhesion molecules of the Contactin family
    Esther T Stoeckli
    University of Zurich, Institute of Molecular Life Sciences, Zurich, Switzerland
    Cell Adh Migr 4:523-6. 2010
  4. pmc RabGDI controls axonal midline crossing by regulating Robo1 surface expression
    Melanie Philipp
    Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland
    Neural Dev 7:36. 2012
  5. doi request reprint Temporal control of gene silencing by in ovo electroporation
    Thomas Baeriswyl
    Institute of Zoology, University of Zurich, Zurich, Switzerland
    Methods Mol Biol 442:231-44. 2008
  6. doi request reprint Sonic hedgehog guides post-crossing commissural axons both directly and indirectly by regulating Wnt activity
    Elena Domanitskaya
    Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland
    J Neurosci 30:11167-76. 2010
  7. ncbi request reprint Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord
    Dimitris Bourikas
    University of Zurich, Institute of Zoology, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nat Neurosci 8:297-304. 2005
  8. doi request reprint Nectin-like molecules/SynCAMs are required for post-crossing commissural axon guidance
    Vera Niederkofler
    Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Development 137:427-35. 2010
  9. doi request reprint Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system
    Marija M Petrinovic
    Brain Research Institute, University of Zurich and Department of Biology, ETH Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Development 137:2539-50. 2010
  10. pmc Expression patterns of plexins and neuropilins are consistent with cooperative and separate functions during neural development
    Olivier Mauti
    Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    BMC Dev Biol 6:32. 2006

Collaborators

Detail Information

Publications21

  1. doi request reprint What does the developing brain tell us about neural diseases?
    Esther T Stoeckli
    Institute of Molecular Life Sciences and Neuroscience, University of Zurich, Zurich, Switzerland
    Eur J Neurosci 35:1811-7. 2012
    ..The processes and genes involved in brain development are linked to the etiologies not only of neurodevelopmental but also of neurodegenerative diseases...
  2. pmc Rostral growth of commissural axons requires the cell adhesion molecule MDGA2
    Pascal Joset
    Brain Research Institute, University of Zurich and Swiss Federal Institute of Technology ETH, Department of Biology, 8057 Zurich, Switzerland
    Neural Dev 6:22. 2011
    ..However, little is known about molecules that provide the basis for commissural axon growth along the anterior-posterior axis...
  3. pmc Neural circuit formation in the cerebellum is controlled by cell adhesion molecules of the Contactin family
    Esther T Stoeckli
    University of Zurich, Institute of Molecular Life Sciences, Zurich, Switzerland
    Cell Adh Migr 4:523-6. 2010
    ..Contactins are required for axon guidance, fasciculation, and synaptogenesis, and thus affect multiple steps in neural circuit formation in the developing cerebellum...
  4. pmc RabGDI controls axonal midline crossing by regulating Robo1 surface expression
    Melanie Philipp
    Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland
    Neural Dev 7:36. 2012
    ..Interestingly, to date no vertebrate homolog of comm has been identified. Robo3/Rig1 has been shown to control Slit sensitivity before the midline, but without affecting Robo1 surface expression...
  5. doi request reprint Temporal control of gene silencing by in ovo electroporation
    Thomas Baeriswyl
    Institute of Zoology, University of Zurich, Zurich, Switzerland
    Methods Mol Biol 442:231-44. 2008
    ..The combination of the easy accessibility of the chicken embryo and RNAi provides a unique opportunity for temporal and spatial control of gene silencing during development...
  6. doi request reprint Sonic hedgehog guides post-crossing commissural axons both directly and indirectly by regulating Wnt activity
    Elena Domanitskaya
    Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland
    J Neurosci 30:11167-76. 2010
    ..Thus, Shh affects post-crossing axon guidance both directly and indirectly by regulating Wnt function...
  7. ncbi request reprint Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord
    Dimitris Bourikas
    University of Zurich, Institute of Zoology, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nat Neurosci 8:297-304. 2005
    ..Rather, functional in vivo studies showed that the repulsive effect of Shh on postcommissural axons was mediated by Hedgehog interacting protein (Hip)...
  8. doi request reprint Nectin-like molecules/SynCAMs are required for post-crossing commissural axon guidance
    Vera Niederkofler
    Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Development 137:427-35. 2010
    ..It is expressed by floorplate cells and interacts with Necls/SynCAMs expressed by commissural axons to mediate a turning response in post-crossing commissural axons...
  9. doi request reprint Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system
    Marija M Petrinovic
    Brain Research Institute, University of Zurich and Department of Biology, ETH Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Development 137:2539-50. 2010
    ..Thus, Nogo-A is a developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching...
  10. pmc Expression patterns of plexins and neuropilins are consistent with cooperative and separate functions during neural development
    Olivier Mauti
    Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    BMC Dev Biol 6:32. 2006
    ..Despite the fact that Plexins are involved in the formation of neuronal circuits, the temporal changes of their expression patterns during development of the nervous system have not been analyzed in detail...
  11. ncbi request reprint Tissue-specific RNA interference
    Melanie Philipp
    Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Biotechnol Genet Eng Rev 22:63-75. 2006
  12. pmc Semaphorin6A acts as a gate keeper between the central and the peripheral nervous system
    Olivier Mauti
    Developmental Neuroscience, Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Neural Dev 2:28. 2007
    ..Based on its very restricted expression in boundary cap cells, we tested for a role of Sema6A as a gate keeper between the CNS and the PNS...
  13. pmc Cell type specific, traceable gene silencing for functional gene analysis during vertebrate neural development
    Nicole H Wilson
    Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nucleic Acids Res 39:e133. 2011
    ..The advancements of the in ovo RNAi technique that we describe will not only markedly enhance functional gene analysis in the chicken, but also could be adapted to other organisms in developmental studies...
  14. ncbi request reprint Longitudinal axon guidance
    Esther T Stoeckli
    Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Curr Opin Neurobiol 16:35-9. 2006
    ..Therefore, it was surprising to find that gradients of two of these morphogens, Wnt4 and Shh, can be re-used for longitudinal axon guidance during later stages of nervous system development...
  15. doi request reprint Sonic Hedgehog regulates Wnt activity during neural circuit formation
    Nicole H Wilson
    Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland
    Vitam Horm 88:173-209. 2012
    ..This review provides an overview of the mechanisms by which Shh signaling acts in concert with Wnts to mediate a myriad of cellular processes that are required for neural circuit formation...
  16. ncbi request reprint New tools for gene manipulation in chicken embryos
    Dimitris Bourikas
    Institute of Zoology, University of Zurich, Switzerland
    Oligonucleotides 13:411-9. 2003
    ..A major advantage of in ovo RNAi is the fact that the knowledge of a cDNA fragment of the gene of interest is sufficient to get loss-of-function phenotypes. Thus, this new approach is a valuable tool for functional genomics...
  17. doi request reprint Gene Silencing by Injection and Electroporation of dsRNA in Avian Embryos
    Olivier Mauti
    Institute of Zoology, University of Zurich, 8057 Zurich, Switzerland
    CSH Protoc 2008:pdb.prot5094. 2008
    ..Proteins with slow turnover may require RNAi at earlier stages, ideally before the onset of gene expression. The electroporation parameters can be adjusted such that only a specific population of neurons is targeted in the spinal cord...
  18. pmc Axonin-1/TAG-1 is required for pathfinding of granule cell axons in the developing cerebellum
    Thomas Baeriswyl
    Institute of Zoology, University of Zurich, Winterthurerstrasse, 8057 Zurich, Switzerland
    Neural Dev 3:7. 2008
    ..Axonin-1/TAG-1 was shown to promote neurite outgrowth in vitro and to be required for commissural and sensory axon pathfinding in vivo...
  19. ncbi request reprint Screening for gene function in chicken embryo using RNAi and electroporation
    Vladimir Pekarik
    University of Zurich, Institute of Zoology, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Nat Biotechnol 21:93-6. 2003
    ..This method opens new possibilities for studying gene function not only by gain-of-function but also by loss-of-function approaches and therefore represents a new tool for functional genomics...
  20. doi request reprint Sonic hedgehog regulates its own receptor on postcrossing commissural axons in a glypican1-dependent manner
    Nicole H Wilson
    Institute of Molecular Life Sciences, Neuroscience Center Zurich, University of Zurich, CH 8057 Zurich, Switzerland
    Neuron 79:478-91. 2013
    ..Our study characterizes a molecular mechanism by which navigating axons switch their responsiveness at intermediate targets. ..
  21. pmc Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance
    Evelyn C Avilés
    Institute of Molecular Life Sciences, University of Zurich Zurich, Switzerland
    Front Cell Neurosci 7:86. 2013
    ..In this review, we will summarize the mechanisms of morphogen function during axon guidance in the vertebrate nervous system...