D Steverding

Summary

Publications

  1. request reprint
    Steverding D, Morgan E, Tkaczynski P, Walder F, Tinsley R. Effect of Australian tea tree oil on Gyrodactylus spp. infection of the three-spined stickleback Gasterosteus aculeatus. Dis Aquat Organ. 2005;66:29-32 pubmed
    ..In addition, Tween 80 alone exhibited parasiticidal activity against Gyrodactylus spp. These findings show the potential of TTO in combination with Tween 80 as an effective treatment of Gyrodactylus spp. infection of fishes. ..
  2. Steverding D, Evans P, Msika L, Riley B, Wallington J, Schelenz S. In vitro antifungal activity of DNA topoisomerase inhibitors. Med Mycol. 2012;50:333-6 pubmed publisher
    ..glabrata and C. neoformans with MIC(50) values in the mid micromolar range. The data of this study indicate that selected DNA topoisomerase inhibitors are a promising class of compounds for the development of new antifungal agents. ..
  3. request reprint
    Steverding D, da Nóbrega F, Rushworth S, de Sousa D. Trypanocidal and cysteine protease inhibitory activity of isopentyl caffeate is not linked in Trypanosoma brucei. Parasitol Res. 2016;115:4397-4403 pubmed
    ..This is supported by a more than 100 times less sensitivity of human HL-60 cells to isopentyl caffeate indicating that the ester has a favourable selectivity profile. ..
  4. Steverding D, Tyler K, Sexton D. Evaluation of marking of peer marking in oral presentation. Perspect Med Educ. 2016;5:103-7 pubmed publisher
    ..Marking of peer marking had a small effect on the marking conduct of students in summative assessment of oral presentation but possibly indicated a more balanced marking performance. ..
  5. Steverding D. The history of leishmaniasis. Parasit Vectors. 2017;10:82 pubmed publisher
    ..Lately, the Syrian civil war and refugee crises have shown that leishmaniasis epidemics can happen any time in conflict areas and neighbouring regions where the disease was previously endemic. ..
  6. Steverding D, Rushworth S. Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. Exp Parasitol. 2017;178:45-50 pubmed publisher
    ..brucei infections and a rationale for its use in combination therapy, particularly with eflornithine or melarsoprol. ..
  7. request reprint
    Steverding D. The significance of transferrin receptor variation in Trypanosoma brucei. Trends Parasitol. 2003;19:125-7 pubmed
    ..This article shows that calculations based on K(d) values argue against the first part of the hypothesis, but might support the second part...
  8. Steverding D, Sexton D, Wang X, Gehrke S, Wagner G, Caffrey C. Trypanosoma brucei: chemical evidence that cathepsin L is essential for survival and a relevant drug target. Int J Parasitol. 2012;42:481-8 pubmed publisher
    ..All inhibitors, except the CATB-specific inhibitor, CA-074, blockaded lysosomal hydrolysis prior to death. The results suggest that TbCATL, rather than TbCATB, is essential to the survival of T. brucei and an appropriate drug target...
  9. Steverding D, Antoszczak M, Huczyński A. In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei. Parasit Vectors. 2016;9:409 pubmed publisher
    ..The data indicate that polyether ionophore derivatives are interesting lead compounds for rational anti-trypanosomal drug development. ..
  10. Steverding D, Huczyński A. Trypanosoma brucei: trypanocidal and cell swelling activities of lasalocid acid. Parasitol Res. 2017;116:3229-3233 pubmed publisher
    ..These results support further investigations of lasalocid acid and derivatives thereof as potential agents against African trypanosomiasis. ..

Detail Information

Publications10

  1. request reprint
    Steverding D, Morgan E, Tkaczynski P, Walder F, Tinsley R. Effect of Australian tea tree oil on Gyrodactylus spp. infection of the three-spined stickleback Gasterosteus aculeatus. Dis Aquat Organ. 2005;66:29-32 pubmed
    ..In addition, Tween 80 alone exhibited parasiticidal activity against Gyrodactylus spp. These findings show the potential of TTO in combination with Tween 80 as an effective treatment of Gyrodactylus spp. infection of fishes. ..
  2. Steverding D, Evans P, Msika L, Riley B, Wallington J, Schelenz S. In vitro antifungal activity of DNA topoisomerase inhibitors. Med Mycol. 2012;50:333-6 pubmed publisher
    ..glabrata and C. neoformans with MIC(50) values in the mid micromolar range. The data of this study indicate that selected DNA topoisomerase inhibitors are a promising class of compounds for the development of new antifungal agents. ..
  3. request reprint
    Steverding D, da Nóbrega F, Rushworth S, de Sousa D. Trypanocidal and cysteine protease inhibitory activity of isopentyl caffeate is not linked in Trypanosoma brucei. Parasitol Res. 2016;115:4397-4403 pubmed
    ..This is supported by a more than 100 times less sensitivity of human HL-60 cells to isopentyl caffeate indicating that the ester has a favourable selectivity profile. ..
  4. Steverding D, Tyler K, Sexton D. Evaluation of marking of peer marking in oral presentation. Perspect Med Educ. 2016;5:103-7 pubmed publisher
    ..Marking of peer marking had a small effect on the marking conduct of students in summative assessment of oral presentation but possibly indicated a more balanced marking performance. ..
  5. Steverding D. The history of leishmaniasis. Parasit Vectors. 2017;10:82 pubmed publisher
    ..Lately, the Syrian civil war and refugee crises have shown that leishmaniasis epidemics can happen any time in conflict areas and neighbouring regions where the disease was previously endemic. ..
  6. Steverding D, Rushworth S. Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. Exp Parasitol. 2017;178:45-50 pubmed publisher
    ..brucei infections and a rationale for its use in combination therapy, particularly with eflornithine or melarsoprol. ..
  7. request reprint
    Steverding D. The significance of transferrin receptor variation in Trypanosoma brucei. Trends Parasitol. 2003;19:125-7 pubmed
    ..This article shows that calculations based on K(d) values argue against the first part of the hypothesis, but might support the second part...
  8. Steverding D, Sexton D, Wang X, Gehrke S, Wagner G, Caffrey C. Trypanosoma brucei: chemical evidence that cathepsin L is essential for survival and a relevant drug target. Int J Parasitol. 2012;42:481-8 pubmed publisher
    ..All inhibitors, except the CATB-specific inhibitor, CA-074, blockaded lysosomal hydrolysis prior to death. The results suggest that TbCATL, rather than TbCATB, is essential to the survival of T. brucei and an appropriate drug target...
  9. Steverding D, Antoszczak M, Huczyński A. In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei. Parasit Vectors. 2016;9:409 pubmed publisher
    ..The data indicate that polyether ionophore derivatives are interesting lead compounds for rational anti-trypanosomal drug development. ..
  10. Steverding D, Huczyński A. Trypanosoma brucei: trypanocidal and cell swelling activities of lasalocid acid. Parasitol Res. 2017;116:3229-3233 pubmed publisher
    ..These results support further investigations of lasalocid acid and derivatives thereof as potential agents against African trypanosomiasis. ..