- [A possible role of genetic translation ambiguity in evolution ]
S G Inge-Vechtomov
St Petersburg State University, St Petersburg, 199034 Russia
Mol Biol (Mosk) 36:268-76. 2002
- Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae
Svetlana E Moskalenko
Universite de Rennes 1, CNRS UMR 6061, IFR 97, France
BMC Mol Biol 4:2. 2003
..The highly conserved translation termination factor eRF1 in Saccharomyces cerevisiae is encoded by the essential gene SUP45...
- [Suppression of nonsense and frameshift mutations obtained by different methods for inactivating the translation termination factor eRF3 in yeast Saccharomyces cerevisiae]
S P Zadorskiĭ
Department of Genetics and Breeding, St Petersburg State University, St Petersburg, 199034 Russia
Genetika 39:489-94. 2003
- [Association between defects of karyogamy and translation termination in yeast Saccharomyces cerevisiae]
A S Borchsenius
Genetika 41:178-86. 2005
..On the strength of the results, an interaction was assumed for translation termination components and cytoskeleton proteins, which play a role in karyogamy in yeasts...
- Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae
V V Kushnirov
Institute of Experimental Cardiology, U S S R Cardiology Research Center, Moscow
Gene 66:45-54. 1988
..One of these proteins is supposed to be imported into mitochondria. Possible functions of the SUP2 gene product(s), especially its putative activity as a soluble factor controlling the fidelity of translation, are discussed...
- [Conservation of the MC domains in eukaryotic termination factor eRF3]
G A Zhuravleva
Genetika 43:38-44. 2007
..At the same time, strains containing the MC domains of the eRF3 proteins from different species differed in growth rate and the efficiency of translation termination...
- [Yeast prions, mammalian amyloidoses, and the problem of proteomic networks]
A P Galkin
Genetika 42:1558-70. 2006
..A hypothesis of proteomic networks is proposed by analogy with prion networks, involving interactions of different amyloids in mammals...
- [Increased tRNA concentration in yeast containing mutant termination translation factors eRF1 and eRF3]
G A Zhuravleva
Mol Biol (Mosk) 40:724-30. 2006
..The majority of the investigated mutations leads to increase in a level of all investigated tRNA. The mechanisms providing viability of nonsense-mutants on essential genes SUP45 and SUP35 are discussed...
- [Frameshift suppression through inactivation of translation termination in yeast Saccharomyces cerevisiae: significance of the local context]
N A Riabnikova
Genetika 40:885-92. 2004
- [Characterization of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1]
S E Moskalenko
Genetika 40:599-606. 2004
..Most of mutations studied do not abolish eRF1-eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed...
- [Chimeric yeast prions with unstable inheritance]
A S Borkhsenius
Department of Genetics and Breeding, St. Petersburg State University, St. Petersburg, 119034 Russia
Genetika 38:300-5. 2002
..The suppressory effect depended on the presence of the prionizing peptide both in the hybrid protein and in Sup35p synthesized from the chromosomal gene, as well as on the presence of the prion-like [PIN] factor in the cell...
- Yeast prion protein derivative defective in aggregate shearing and production of new 'seeds'
A S Borchsenius
School of Biology and Institute for Bioengineering and Bioscience, Atlanta, GA 30332-0363, USA
EMBO J 20:6683-91. 2001
..Our results shed light on the mechanisms determining the differences between transmissible prions and non-transmissible protein aggregates...
- [Suppression of frameshift mutation as a result of partial inactivation of translation termination factors in Saccharomyces cerevisiae yeast]
V N Kulikov
Department of Genetics and Breeding, St. Petersburg State University, St. Petersburg, 199034 Russia
Genetika 37:602-9. 2001
..Alternative mechanisms of programmed translational frameshifting in the course of translation and the possibility of enhancing the effectiveness of such frameshifting in the presence of the [PSI] factor are considered...
- [Viable nonsense mutants for the SUP45 gene in the yeast Saccharomyces cerevisiae are lethal at increased temperature]
G A Zhuravleva
Genetika 43:1363-71. 2007
..The results of this study suggest that the N-terminal eRF1 fragment is indispensable for cell viability of nonsense mutants due to the involvement in termination of translation...