Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) studyNattachai Srisawat
The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Crit Care 14:R46. 2010
..The aim of this study was to estimate the cost difference between CRRT and IRRT in the intensive care unit (ICU)...
Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumoniaNattachai Srisawat
The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
Kidney Int 80:545-52. 2011
..Thus, in this cohort of patients with pneumonia-induced severe acute kidney injury, plasma NGAL appears to be a useful biomarker for predicting renal recovery...
Urinary biomarkers and renal recovery in critically ill patients with renal supportNattachai Srisawat
604 Scaife Hall, Department of Critical Care Medicine, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Clin J Am Soc Nephrol 6:1815-23. 2011
..Unfortunately, no reliable method to predict renal recovery exists. The discovery of biomarkers to aid in clinical risk prediction for recovery after AKI would represent a significant advance over current practice...
Bactericidal antibiotics temporarily increase inflammation and worsen acute kidney injury in experimental sepsisZhi Yong Peng
Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 40:538-43. 2012
..To explore the relationships among bactericidal antimicrobial treatment of sepsis, inflammatory response, severity of acute kidney injury, and outcomes...
Acute kidney injury: definition, epidemiology, and outcomeNattachai Srisawat
Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Curr Opin Crit Care 17:548-55. 2011
..This review aims to highlight the recent advances in AKI epidemiology as well as to suggest future directions for prevention and management...
Is there a difference between strong ion gap in healthy volunteers and intensive care unit patients?Kyle J Gunnerson
The CRISMA Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Crit Care 25:520-4. 2010
..Thus, we conducted this pilot study to examine differences in quantitative acid-base variables between healthy adult volunteers and stable ICU patients with no suspected acid-base abnormalities...
Modern classification of acute kidney injuryNattachai Srisawat
The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Blood Purif 29:300-7. 2010
..The RIFLE criteria have been extensively validated in more than 550,000 patients worldwide...
Recovery from acute kidney injury: determinants and predictorsNattachai Srisawat
The Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Contrib Nephrol 165:284-91. 2010
..This review will describe the current understanding of the renal recovery process, and the role of clinical severity scores and novel biomarkers such as NGAL, HGF, and cystatin C in predicting renal recovery...