Research Topics

Genomes and Genes

Species

Eric H Karunanayake

Summary

Affiliation: University of Colombo
Country: Sri Lanka

Publications

  1. Ranasinghe R, Tennekoon K, Karunanayake E, Lembring M, Allen M. A study of genetic polymorphisms in mitochondrial DNA hypervariable regions I and II of the five major ethnic groups and Vedda population in Sri Lanka. Leg Med (Tokyo). 2015;17:539-46 pubmed publisher
    ..Thus this study provides useful information for forensic analysis and anthropological studies of Sri Lankans. ..
  2. Senathilake K, Karunanayake E, Samarakoon S, Tennekoon K, de Silva E. Rhizome extracts of Curcuma zedoaria Rosc induce caspase dependant apoptosis via generation of reactive oxygen species in filarial parasite Setaria digitata in vitro. Exp Parasitol. 2016;167:50-60 pubmed publisher
  3. Senathilake K, Karunanayake E, Samarakoon S, Tennekoon K, de Silva E, Adhikari A. Oleanolic acid from antifilarial triterpene saponins of Dipterocarpus zeylanicus induces oxidative stress and apoptosis in filarial parasite Setaria digitata in vitro. Exp Parasitol. 2017;177:13-21 pubmed publisher
    ..Compound 3/oleanolic acid was thus identified as a potent and safe antifilarial compound in vitro. ..
  4. De Silva W, Karunanayake E, Tennekoon K, Allen M, Amarasinghe I, Angunawala P, et al. Novel sequence variants and a high frequency of recurrent polymorphisms in BRCA1 gene in Sri Lankan breast cancer patients and at risk individuals. BMC Cancer. 2008;8:214 pubmed publisher
    ..3086delT and c.5404delG) in two families were identified and two more possibly pathogenic mutations (c.856T>G and IVS17-2A>T) in two families were identified. BRCA1--Gene Bank: Accession # U14680 Version # 14680.1. ..