Kjetil Søreide

..Mortality ranges from 3-40% and several prognostic scoring systems have been suggested. The aim of this study was to review the available scoring systems for PPU patients, and to assert if there is evidence to prefer one to the other...

..Protective gear including helmet and pads may help to prevent such injuries, while more complex knowledge of human factors, environment and training are needed to prevent fatal injuries...

..The aim of this study was to investigate the role of c-KIT and PDGFRA gene mutations in primary resectable, imatinib naïve GISTs located in the stomach and small intestine...

..This study evaluated the feasibility of collecting the data variables of the international consensus-derived Utstein Trauma Template...

..Little is known about surgeons' adherence to such guidelines. In this national survey we analyse adherence and attitudes to postoperative follow up among Norwegian gastrointestinal surgeons involved in the care of patients with CRC...

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..Insight into cause and time of fatal pediatric and adolescent trauma is important for planning trauma care and preventive measures. Our aim was to analyze cause, severity, mode and seasonal aspects of fatal pediatric trauma...

..The objective of the current study was to investigate the effect of microsatellite instability (MSI) and DNA ploidy on surveillance after surgery...

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..Influence of genetic instability on tumor marker expression is not known. The aim of this study was to investigate microsatellite instability (MSI) of CEA serum levels in locally advanced CRC...

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..Formal requirements in training duration and educational content are likely to change. Recruitment to surgery and ensuring continuity of patient care take surgery in Norway beyond the scalpel into the 21st century...

..Lastly, the importance of recognizing bias and pitfalls and the adherence to guidelines for biomarker research are addressed...

..The effect of tumor-related factors associated with lymph node harvest is not well understood as data are lacking. We investigated tumor-related factors in relation to the number of lymph nodes harvested...

..Little is known about what factors surgeons hold important when choosing a journal for article submission...

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..This study examines patterns in trauma deaths to the occurrence in hour and time of the day, day and time in the week, and month and season...

..In this review, we discuss the fundamental roles, suggested presentation, potential biases, and interpretation of ROC analysis in surgical research...

..MSI is identified through the use of several markers. The aim of this study was to test the fidelity of five markers for high-frequency MSI (MSI-H) across age groups and stages...

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..Based on an updated review of the current available literature, this paper presents the current evidence regarding the rationale, risk, and outcomes for employing EDT in the field of trauma surgery...

..This review aims to give an overview of the evolving biomarker concepts in CRC, with concerns on methods, and potential for clinical implications for the surgical oncologist...

..This study provides a baseline overview of the temporal patterns in these four indicators over the past four decades in Norway...

..Current survival-estimates and recommended guidelines are based on data from the United States. However, reports from European trauma centres are lacking. We report the current experience from a Scandinavian trauma hospital...

..Although the basic mechanisms are not clear, there is increased understanding of the clinicopathological consequences of MSI...

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..Presenting symptoms include a rash, arthralgia, abdominal pain, and, frequently, renal involvement. Genitourinary symptoms are infrequently reported; however, surgical evaluation is often required...

..An appendiceal mucinous neoplasia is sometimes diagnosed during a laparotomy performed on another indication. Frequently, the condition remains undiagnosed until the pathologists' examination...

..As all other differentials had been ruled out, we concluded that Henoch-Schönlein syndrome was the cause of the recurrent scrotal pain in our patient...

..Bile duct cysts (BDC) are rare, of uncertain origin, and occur most often in young females of Asian descent. Increasingly, BDCs are reported in the Western population, often with coexistent biliary tract cancer...

..This article presents an update on carcinogenesis and classification, according to the increased understanding of precursors and the improved insight into molecular biological mechanisms...

..The present knowledge and controversies pertaining to molecular testing of MSI and MMR defects in CRC are presented...

..The epidemiology of trauma deaths in Europe is less than well investigated. Thus, our goal was to study the contemporary patterns of trauma deaths within a defined population with an exceptionally high trauma autopsy rate...

..Associated with risk for injuries and deaths, this activity may pose a burden on the emergency system. Hitherto, no reports exist on accidents and deaths associated with BASE jumping...

..We sought to validate biomarkers predictive of metachronous colorectal cancer (mCRC) in patients with sporadic colorectal adenomas, using 374 consecutive patients from a large defined population...

..The diagnostic accuracy of continuous tests depends on the choice of cut-off values. We analyzed the diagnostic accuracy of serial CRP and WBC measurements to detect infectious complications after colorectal resections...

..Systematic surveillance after curative resection is common practice in Norway. The article presents the scientific grounds for surveillance in general, and for the Norwegian guidelines in particular...

..To investigate the prognostic value of occult metastases detected by quantitative measurements of candidate biomarkers in sentinel lymph nodes (SLNs) from patients curatively resected for colon cancer...

..Epidemiology of gastrointestinal stromal tumour (GIST) is sparsely described. We report a population-based consecutive case series of GIST over three decades from south-western Norway...

..The triangular relationship between oestrogen receptor, tamoxifen and ApoD should be further explored...

..This suggests that future research should focus on these differences of excess mortality in patients curatively treated for cancer of the colon and rectum...

..To investigate the epidemiological trends in incidence and mortality of perforated peptic ulcer (PPU) in a well-defined Norwegian population...

..Hurler's syndrome is a rare congenital metabolic disorder and is inevitably lethal when untreated. The presenting symptoms are usually vague, resembling those found in otherwise healthy children...

..Only a few studies have evaluated its overall utility. The aim of this study was to investigate changes in surgical management of PPU and associated outcomes...

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..The main objective of this study was to describe and evaluate contemporary use of ERCP in Norway...

..Thus, we prospectively investigated the age- and sex-specific incidence patterns of long-bone fractures in a defined population...

..Etiology is unknown; definitions and terminology are confusing, and preoperative diagnosis is difficult. Several differential diagnoses must be considered...

..This study aimed to provide national figures on ERCP in Norway over the last decade...

..A fracture and dislocation registry was established within a well-defined population. An audit of the establishment process, feasibility of the registry work and report of the collected data is given...