Ioan Sporea

Summary

Publications

  1. pmc Why, who and how should perform liver biopsy in chronic liver diseases
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Timisoara 700736, Romania
    World J Gastroenterol 14:3396-402. 2008
  2. ncbi Colonoscopy in Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Iosif Bulbuca 156, 300736 Timisoara, Romania
    Rom J Gastroenterol 14:15-8. 2005
  3. ncbi Sedation during colonoscopy
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Iosif Bulbuca 156, Timisoara, Romania
    Rom J Gastroenterol 14:195-8. 2005
  4. ncbi Pegylated-interferon alpha 2a treatment for chronic hepatitis C in patients on chronic haemodialysis
    Ioan Sporea
    University of Medicine and Pharmacy, Department of Gastroenterology, Timisoara, Romania
    World J Gastroenterol 12:4191-4. 2006
  5. ncbi Efficacy, tolerability and predictive factors for early and sustained virologic response in patients treated with weight-based dosing regimen of PegIFN alpha-2b ribavirin in real-life healthcare setting
    Liana Gheorghe
    Department of Hepatology, Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Str Fundeni no 258, 72437 Bucharest, Romania
    J Gastrointestin Liver Dis 16:23-9. 2007
  6. ncbi The survey on the practice of gastroenterology in Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Ion Bulbuca 156, Timisoara, Romania
    J Gastrointestin Liver Dis 15:313-6. 2006
  7. ncbi Liver stiffness measurement by transient elastography in clinical practice
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Timisoara 13 Snagov Str, Timisoara, Romania
    J Gastrointestin Liver Dis 17:395-9. 2008
  8. ncbi How to improve the performances in diagnostic colonoscopy?
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Timisoara, Romania
    J Gastrointestin Liver Dis 16:363-7. 2007
  9. ncbi The quality of the fragment obtained by liver biopsy for staging chronic hepatitis
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Snagov 13, 300482 Timişoara, Romania
    J Gastrointestin Liver Dis 16:263-6. 2007
  10. ncbi Comparative study concerning the efficacy of Peg-IFN alpha-2a versus Peg-IFN alpha-2b on the early virological response (EVR) in patients with chronic viral C hepatitis
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Ion Bulbuca no 156, Timisoara, Romania
    J Gastrointestin Liver Dis 15:125-30. 2006

Detail Information

Publications73

  1. pmc Why, who and how should perform liver biopsy in chronic liver diseases
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Timisoara 700736, Romania
    World J Gastroenterol 14:3396-402. 2008
    ....
  2. ncbi Colonoscopy in Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Iosif Bulbuca 156, 300736 Timisoara, Romania
    Rom J Gastroenterol 14:15-8. 2005
    ..AIM of this paper was to assess if and how is Romania prepared to cope with screening of colon cancer by means of colonoscopy...
  3. ncbi Sedation during colonoscopy
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Iosif Bulbuca 156, Timisoara, Romania
    Rom J Gastroenterol 14:195-8. 2005
    ..042). We believe that the strategy of sedation during colonoscopy in Romania should be changed so that all the patients should benefit from sedo-analgesia, proved to be safe and cost/efficient...
  4. ncbi Pegylated-interferon alpha 2a treatment for chronic hepatitis C in patients on chronic haemodialysis
    Ioan Sporea
    University of Medicine and Pharmacy, Department of Gastroenterology, Timisoara, Romania
    World J Gastroenterol 12:4191-4. 2006
    ..To evaluate the response to pegylated-interferon alpha 2a in chronic hepatitis C patients on chronic haemodialysis...
  5. ncbi Efficacy, tolerability and predictive factors for early and sustained virologic response in patients treated with weight-based dosing regimen of PegIFN alpha-2b ribavirin in real-life healthcare setting
    Liana Gheorghe
    Department of Hepatology, Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Str Fundeni no 258, 72437 Bucharest, Romania
    J Gastrointestin Liver Dis 16:23-9. 2007
    ....
  6. ncbi The survey on the practice of gastroenterology in Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Ion Bulbuca 156, Timisoara, Romania
    J Gastrointestin Liver Dis 15:313-6. 2006
    ..To get data on the current practice of Gastroenterology in Romania...
  7. ncbi Liver stiffness measurement by transient elastography in clinical practice
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Timisoara 13 Snagov Str, Timisoara, Romania
    J Gastrointestin Liver Dis 17:395-9. 2008
    ..The AIM of our study was to evaluate the results of transient elastography assessment of liver stiffness (LS) in various categories of patients...
  8. ncbi How to improve the performances in diagnostic colonoscopy?
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Timisoara, Romania
    J Gastrointestin Liver Dis 16:363-7. 2007
    ..Endoscopic colonoscopy seems to be the most useful tool for screening for colorectal cancer, but experienced endoscopists are required. The..
  9. ncbi The quality of the fragment obtained by liver biopsy for staging chronic hepatitis
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Snagov 13, 300482 Timişoara, Romania
    J Gastrointestin Liver Dis 16:263-6. 2007
    ..The aim of our paper was to assess the quality of the liver fragment obtained by liver biopsy for staging chronic hepatitis...
  10. ncbi Comparative study concerning the efficacy of Peg-IFN alpha-2a versus Peg-IFN alpha-2b on the early virological response (EVR) in patients with chronic viral C hepatitis
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Str Ion Bulbuca no 156, Timisoara, Romania
    J Gastrointestin Liver Dis 15:125-30. 2006
    ..The AIM of our paper was to compare the efficacy of Peg-IFN alpha 2a (Pegasys) and Peg-IFN alpha 2b (PegIntron) in a group of patients from the Department of Gastroenterology in Timisoara...
  11. ncbi Assessment of the quality of colonoscopy in Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy Timisoara, Romania
    Rom J Gastroenterol 14:303-7. 2005
    ..6%) (p=0.000027). Regarding sedation during colonoscopy, in 46% of the cases the colonoscopy was performed without sedation and in 54% of the cases with sedation (or sedo-analgesia)...
  12. ncbi Can ARFI elastography predict the presence of significant esophageal varices in newly diagnosed cirrhotic patients?
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Ann Hepatol 11:519-25. 2012
    ..To establish an algorithm which includes the liver stiffness (LS) and/or spleen stiffness (SS) assessed by ARFI for the prediction of significant esophageal varices-EV (at least grade 2)...
  13. ncbi The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: a retrospective multicentre study
    Simona Bota
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Electronic address
    Dig Liver Dis 45:762-8. 2013
    ..Acoustic Radiation Force Impulse Elastography is a new method for non-invasive evaluation of liver fibrosis...
  14. ncbi Peg-Interferon Alfa 2a (40kDa) in patients on chronic haemodialysis with chronic C hepatitis. Preliminary results
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Rom J Gastroenterol 13:99-102. 2004
    ..The sustained response will be established by determining PCR RNA-HCV 6 months after the end of the treatment...
  15. ncbi The contribution of contrast enhanced ultrasound for the characterization of benign liver lesions in clinical practice - a monocentric experience
    Alina Martie
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 14:283-7. 2012
    ..Contrast-enhanced ultrasound (CEUS) uses second generation microbubble contrast agents and is considered to be a useful imaging method for focal liver lesions (FLLs) characterization...
  16. ncbi  Does the size of the needle influence the number of portal tracts obtained through percutaneous liver biopsy?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Ann Hepatol 11:691-5. 2012
    ..Liver biopsy (LB) is often essential for the diagnosis and staging of chronic viral hepatitis. The aim of our paper was to establish if the size of the biopsy needle influences the number of portal tracts obtained through LB...
  17. ncbi Outcome of antiviral treatment in patients with chronic genotype 1 HCV hepatitis. A retrospective study in 507 patients
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    J Gastrointestin Liver Dis 19:261-4. 2010
    ..The aim of our paper was to verify if there are significant differences regarding the sustained virologic response (SVR) in patients treated with PegIFN alfa-2a vs. those treated PegIFN alpha-2b, both in combination with ribavirin...
  18. ncbi Does experience play a role in the ability to perform liver stiffness measurements by means of supersonic shear imaging (SSI)?
    Oana Gradinaru-Tascău
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 15:180-3. 2013
    ....
  19. ncbi Are different cut-off values of liver stiffness assessed by transient elastography according to the etiology of liver cirrhosis for predicting significant esophageal varices?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 15:111-5. 2013
    ..viral etiology of cirrhosis...
  20. doi Role of interleukin-28B polymorphism as a predictor of sustained virological response in patients with chronic hepatitis C treated with triple therapy: a systematic review and meta-analysis
    Simona Bota
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, 10, Iosif Bulbuca Blv, 300736, Timisoara, Romania
    Clin Drug Investig 33:325-31. 2013
    ....
  21. ncbi Contrast Enhanced Ultrasound for the evaluation of focal liver lesions in daily practice. A multicentre study
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Med Ultrason 14:95-100. 2012
    ..The purpose of this study was to present the experience of four Romanian centers in the evaluation of FLLs by contrast enhanced ultrasound (CEUS), in daily practice...
  22. ncbi Response to standard of care antiviral treatment in patients with HCV liver cirrhosis - a systematic review
    Simona Bota
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    J Gastrointestin Liver Dis 20:293-8. 2011
    ....
  23. ncbi Contrast enhanced ultrasound for the characterization of focal liver lesions
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, 13, Snagov str, 300482 Timişoara, Romania
    Med Ultrason 13:38-44. 2011
    ..to present the practice of two experienced centres concerning the use of contrast enhanced ultrasound (CEUS) in the characterization of focal liver lesions (FLL)...
  24. ncbi Contrast enhanced ultrasound for the diagnosis of liver hemangiomas in clinical practice
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 13:95-101. 2011
    ..Contrast enhanced ultrasound (CEUS) has a well established place in the characterization of focal liver lesions (FLL). The aim of this paper was to evaluate the usefulness of CEUS in the assessment of liver hemangiomas...
  25. ncbi Spleen assessment by Acoustic Radiation Force Impulse Elastography (ARFI) for prediction of liver cirrhosis and portal hypertension
    Simona Bota
    Department of Gastroenterology and Hepatology University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 12:213-7. 2010
    ....
  26. ncbi Contrast enhanced ultrasound for the characterization of hepatocellular carcinoma
    Alina Martie
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara
    Med Ultrason 13:108-13. 2011
    ..The purpose of this study is to present our experience concerning the use of CEUS in the characterization of HCCs...
  27. ncbi The mean values of liver stiffness assessed by Acoustic Radiation Force Impulse elastography in normal subjects
    Alina Popescu
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Victor Babes, Barbu Iscovescu str 8, 300561, Timisoara, Romania
    Med Ultrason 13:33-7. 2011
    ..The AIM of this paper is to establish the values of liver stiffness (LS) assessed by means of ARFI in patients without known liver pathology and considered healthy subjects...
  28. ncbi Acoustic radiation force impulse and supersonic shear imaging versus transient elastography for liver fibrosis assessment
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Electronic address
    Ultrasound Med Biol 39:1933-41. 2013
    ..4% of patients, reliable liver stiffness measurements were obtained using all three elastographic methods, and ARFI imaging and TE were similarly accurate in diagnosing significant fibrosis and cirrhosis, with TE as the reference method...
  29. doi Meta-analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis
    Simona Bota
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Liver Int 33:1138-47. 2013
    ..This meta-analysis aims to compare the diagnostic performance of acoustic radiation force impulse (ARFI) elastography and transient elastography (TE) in the assessment of liver fibrosis using liver biopsy (LB) as 'gold-standard'...
  30. doi Factors which influence the accuracy of acoustic radiation force impulse (ARFI) elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis C
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Ultrasound Med Biol 39:407-12. 2013
    ..003) were associated with discordances. In a multivariate analysis, the female sex (p = 0.006) and IQR ≥30% (p = 0.004) were associated with discordances. Therefore, IQR parameter should be used for ARFI measurements...
  31. ncbi The value of contrast enhanced ultrasound in the evaluation of the nature of portal vein thrombosis
    Mirela Danila
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara
    Med Ultrason 13:102-7. 2011
    ..Ultrasound (US) is the first imaging method used for assessing PVT...
  32. pmc Is it better to use two elastographic methods for liver fibrosis assessment?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, 10 Iosif Bulbuca Bv 300736 Timisoara, Romania
    World J Gastroenterol 17:3824-9. 2011
    ..To find out if by combining 2 ultrasound based elastographic methods: acoustic radiation force impulse (ARFI) elastography and transient elastography (TE), we can improve the prediction of fibrosis in patients with chronic hepatitis C...
  33. pmc Comparison of the liver stiffness measurement by transient elastography with the liver biopsy
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, 13, Snagov str, Timisoara 300472, Romania
    World J Gastroenterol 14:6513-7. 2008
    ..To compare the liver stiffness (LS) measurement by transient elastography (TE) to the liver biopsy (LB)-considered the "gold standard" in the evaluation of patients with chronic hepatitis C...
  34. pdf Transient elastographic evaluation of subjects without known hepatic pathology: does age change the liver stiffness?
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania
    J Gastrointestin Liver Dis 18:57-60. 2009
    ..The aim of this paper is to evaluate the liver stiffness (LS) measured by transient elastography in individuals without known hepatic pathology ("normal" subjects) and to see if it is influenced by age...
  35. doi Liver stiffness measurements by means of supersonic shear imaging in patients without known liver pathology
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes, University of Medicine and Pharmacy, Timisoara, Romania
    Ultrasound Med Biol 39:1362-7. 2013
    ..Thus, 6 kPa is the mean SSI value in patients without known liver pathology, with higher values being obtained in men. ..
  36. doi The influence of food intake on liver stiffness values assessed by acoustic radiation force impulse elastography-preliminary results
    Alina Popescu
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Ultrasound Med Biol 39:579-84. 2013
    ..1.27 ± 0.23, p = 0.06). In the control group, the mean LS values were similar in all 3 measurements. In conclusion, food intake significantly increased the LS values, thus ARFI measurements should be performed in fasting conditions...
  37. doi Acoustic Radiation Force Impulse elastography for fibrosis evaluation in patients with chronic hepatitis C: an international multicenter study
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Eur J Radiol 81:4112-8. 2012
    ..The aim of this international multicenter study was to evaluate the reliability of Acoustic Radiation Force Impulse (ARFI) elastography for predicting fibrosis severity, in patients with chronic hepatitis C...
  38. ncbi Contrast enhanced ultrasound in focal liver lesions--a cost efficiency study
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 12:280-5. 2010
    ..Contrast enhanced ultrasound (CEUS) has a well established role for the evaluation of focal liver lesions (FLL). The AIM of our paper was to evaluate if CEUS is a cost-efficient method for the first line evaluation of FLL...
  39. ncbi How useful is contrast enhanced ultrasonography for the characterization of focal liver lesions?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    J Gastrointestin Liver Dis 19:393-8. 2010
    ....
  40. pmc A new scoring system for prediction of fibrosis in chronic hepatitis C
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Hepat Mon 11:548-55. 2011
    ..Liver biopsy (LB) is still considered to be the gold standard for assessment of liver fibrosis...
  41. doi Factors influencing reliability of liver stiffness measurements using transient elastography (M-probe)-monocentric experience
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania
    Eur J Radiol 82:e313-6. 2013
    ..To retrospectively assess the feasibility of transient elastography (TE) and the factors associated with failed and unreliable liver stiffness measurements (LSMs), in patients with chronic liver diseases...
  42. ncbi Can transient elastography be a reliable method for assessing liver fibrosis in non alcoholic steatohepatitis (NASH)?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 15:106-10. 2013
    ..The aim of our study was to evaluate the severity of liver damage in non-alcoholic steatohepatitis (NASH) patients, by means of Transient Elastography (TE), using prespecified cut-off values of liver stiffness (LS) measurements...
  43. ncbi How many measurements are needed for liver stiffness assessment by 2D-Shear Wave Elastography (2D-SWE) and which value should be used: the mean or median?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Email
    Med Ultrason 15:268-72. 2013
    ..To analyze how many measurements are needed for non-invasive assessment of liver stiffness (LS) by means of 2D-Shear Wave Elastography (2D-SWE) and if the use of mean of median values of 2D-SWE measurements is needed...
  44. pmc The Correlation of Il28B Genotype With Sustained Virologic Response In Romanian patients With Chronic Hepatitis C
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Hepat Mon 11:975-9. 2011
    ..Multiple variables influencing the sustained virologic response (SVR) in chronic hepatitis C have been evaluated. One of them is genetic polymorphism near the IL28B gene...
  45. pmc How efficient is acoustic radiation force impulse elastography for the evaluation of liver stiffness?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Hepat Mon 11:532-8. 2011
    ..The lack of sensitivity to detect fibrosis, because of its heterogeneity is a drawback of liver biopsy (LB)...
  46. ncbi The role of contrast enhanced ultrasound (CEUS) in the assessment of liver nodules in patients with cirrhosis
    Mirela Danila
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Martir Petru Domasneanu str, Bl 73, ap 9, 300351 Timisoara, Romania
    Med Ultrason 12:145-9. 2010
    ..The differential diagnosis between a regenerative nodule, a dysplastic one and hepatocellular carcinoma is made based on a contrast imaging method (CEUS, MRI or CT) as they all have comparative sensitivities...
  47. ncbi Contrast enhanced ultrasound (CEUS) in the evaluation of liver metastases
    Mirela Danila
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Timisoara, Romania
    Med Ultrason 12:233-7. 2010
    ..All liver metastases present wash-out in the portal and late phases, a typical enhancement pattern. CEUS sensitivity is superior to standard ultrasound for the diagnosis of liver metastases being similar to the one of contrast CT...
  48. ncbi Factors that influence the correlation of acoustic radiation force impulse (ARFI), elastography with liver fibrosis
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Med Ultrason 13:135-40. 2011
    ..We assessed the following factors: the success rate (SR) and interquartile range (IQR) interval, the place where ARFI was performed, liver steatosis, the quality of the specimen obtained by LB...
  49. pmc Liver stiffness measurements in patients with HBV vs HCV chronic hepatitis: a comparative study
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, 300736 Timisoara, Romania
    World J Gastroenterol 16:4832-7. 2010
    ..To assess the values of liver stiffness (LS) in patients with hepatitis B virus (HBV) chronic hepatitis and to compare them with those in patients with hepatitis C virus (HCV) chronic hepatitis...
  50. pmc Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: A systematic review
    Simona Bota
    Simona Bota, Ioan Sporea, Roxana Şirli, Alina Popescu, Mirela Dănilă, Mihnea Străin, Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, 300736 Timisoara, Romania
    World J Hepatol 5:120-6. 2013
    ..To identify severe adverse events (SAEs) leading to treatment discontinuation that occur during antiviral therapy in hepatitis C virus (HCV)-infected cirrhotic patients...
  51. doi Comparative study concerning the value of acoustic radiation force impulse elastography (ARFI) in comparison with transient elastography (TE) for the assessment of liver fibrosis in patients with chronic hepatitis B and C
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Ultrasound Med Biol 38:1310-6. 2012
    ..In conclusion, for the same stage of fibrosis, the mean LS values by ARFI were similar in patients with chronic hepatitis B and C. ARFI had similar predictive value with TE in both chronic viral hepatitis...
  52. doi Intra- and interoperator reproducibility of acoustic radiation force impulse (ARFI) elastography--preliminary results
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Ultrasound Med Biol 38:1103-8. 2012
    ..88 vs. 0.91 and 0.79 vs. 0.82, respectively), in patients with ascites vs. no ascites (0.80 vs. 0.93 and 0.78 vs. 0.84, respectively) and in noncirrhotic vs. cirrhotic patients (0.77 vs. 0.82 and 0.70 vs. 0.83, respectively)...
  53. pmc Value of transient elastography for the prediction of variceal bleeding
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy Timisoara, 300482 Timişoara, Romania
    World J Gastroenterol 17:2206-10. 2011
    ..To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding...
  54. ncbi The influence of liver residual mass on the values of Acoustic Radiation Force Impulse Elastography (ARFI) in cirrhotic patients
    Simona Bota
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Timisoara, Romania
    Med Ultrason 13:195-9. 2011
    ..The aim of our study was to assess the influence of liver residual mass in cirrhotic patients on the liver stiffness (LS), measured by ARFI elastography...
  55. ncbi Colonoscopy and sedation in Romania: early experience using a balanced propofol regimen
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Snagov Str 13, 300842 Timisoara, Romania
    J Gastrointestin Liver Dis 19:27-30. 2010
    ..The aim of this study was to evaluate if the sedation during colonoscopy is correctly performed in our patients, especially because it is usually performed by residents in anesthesiology...
  56. ncbi Comparison between the M and XL probes for liver fibrosis assessment by transient elastography
    Roxana Sirli
    Department of Gastroenterology and Hepatology, Victor Babes University and Medicine Timisoara, Romania
    Med Ultrason 16:119-22. 2014
    ..The aim of our paper was to assess the usefulness of the XL probe in daily clinical practice...
  57. ncbi Romanian national guidelines and practical recommendations on liver elastography
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania
    Med Ultrason 16:123-38. 2014
    ....
  58. doi Which are the cut-off values of 2D-Shear Wave Elastography (2D-SWE) liver stiffness measurements predicting different stages of liver fibrosis, considering Transient Elastography (TE) as the reference method?
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Electronic address
    Eur J Radiol 83:e118-22. 2014
    ..To identify liver stiffness (LS) cut-off values assessed by means of 2D-Shear Wave Elastography (2D-SWE) for predicting different stages of liver fibrosis, considering Transient Elastography (TE) as the reference method...
  59. ncbi Liver elastography for the diagnosis of portal hypertension in patients with liver cirrhosis
    Roxana Sirli
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Victor Babes Timisoara, Romania
    Med Ultrason 14:225-30. 2012
    ..Probably the accuracy of ARFI elastography can be significantly increased if spleen stiffness is assessed, alone or in combination with liver stiffness and other parameters...
  60. ncbi Acoustic Radiation Force Impulse (ARFI)--a new modality for the evaluation of liver fibrosis
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy Timisoara, str Snagov nr 13, 300482 Timişoara, Romania
    Med Ultrason 12:26-31. 2010
    ..to assess the accuracy of transient elastography (TE) and Acoustic Radiation Force Impulse (ARFI) for liver fibrosis assessment, as compared to percutaneous liver biopsy (LB) in patients with chronic hepatitis...
  61. ncbi Ultrasound assisted liver biopsy for the staging of diffuse chronic hepatopathies
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Timisoara, Romania
    Rom J Gastroenterol 13:287-90. 2004
    ..96% of the cases. In conclusion, ultrasound-assisted liver biopsy is still the "gold standard" of hepatologic evaluation, being a safe and accurate method for staging the diffuse chronic hepatopathies...
  62. pmc Assessment of noninvasive liver stiffness in inactive HBsAg carriers by transient elastography: Fibroscan in inactive HBsAg carriers
    Ioan Sporea
    Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Hepat Mon 11:182-5. 2011
    ..Chronic viral hepatitis can be evaluated using invasive or noninvasive methods...
  63. pmc Is ARFI elastography reliable for predicting fibrosis severity in chronic HCV hepatitis?
    Ioan Sporea
    Ioan Sporea, Roxana Şirli, Simona Bota, Alina Popescu, Mirela Dănilă, Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, 10 Iosif Bulbuca Bv, 300736 Timisoara, Romania
    World J Radiol 3:188-93. 2011
    ..To determine whether acoustic radiation force impulse (ARFI) elastography is a reliable method for predicting fibrosis severity in patients with chronic hepatitis C virus (HCV) hepatitis...
  64. pmc Value of acoustic radiation force impulse elastography for the assessment of ascites syndrome
    Simona Bota
    Simona Bota, Ioan Sporea, Roxana Şirli, Alina Popescu, Mirela Dănilă, Mădălina Şendroiu, Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, 300742, Timisoara, Romania
    World J Radiol 3:205-9. 2011
    ..To assess the feasibility of performing acoustic radiation force impulse (ARFI) elastography in patients with ascites and its predictive value for the cirrhotic or non-cirrhotic etiology of ascites...
  65. pmc How often hepatocellular carcinoma has a typical pattern in contrast enhanced ultrasound?
    Alina Martie
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Maedica (Buchar) 7:236-40. 2012
    ..6%) (p<0.001).Conclusions: 69.3% of all hepatocellular carcinoma had a typical enhancement pattern on Contrast Enhanced Ultrasound, performing better in nodules larger than 3 cm, than in smaller nodules (p<0.001)...
  66. pmc A comparative study of non-invasive methods for fibrosis assessment in chronic HCV infection
    Roxana Sirli
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timisoara, Romania
    Hepat Mon 10:88-94. 2010
    ....
  67. ncbi Ultrasound examination of the normal pancreas
    Roxana Sirli
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Romania
    Med Ultrason 12:62-5. 2010
    ..For a correct evaluation of the pancreas all its segments must be visualized: head, uncinate process, body, and tail - the latter being the most difficult to visualize...
  68. pmc ARFI elastography for the evaluation of diffuse thyroid gland pathology: Preliminary results
    Ioan Sporea
    Ioan Sporea, Roxana Şirli, Simona Bota, Alina Popescu, Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, 300736 Timisoara, Romania
    World J Radiol 4:174-8. 2012
    ..To assess whether acoustic radiation force impulse (ARFI) elastography can differentiate normal from pathological thyroid parenchyma...
  69. ncbi Percutaneous ethanol injection therapy in the treatment of hepatocarcinoma--results obtained from a series of 88 cases
    Mirela Danila
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Martir Petru Dămăşneanu Str 73 300351 Timişoara, Romania
    J Gastrointestin Liver Dis 18:317-22. 2009
    ..To assess the efficacy of Percutaneous Ethanol Injection Therapy (PEIT) for the treatment of hepatocarcinoma in a series of Romanian patients, and to compare it with previous studies...
  70. ncbi Ultrasound examination of the normal gastrointestinal tract
    Ioan Sporea
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, 13 Snagov Str, 300482 Timişoara, Romania
    Med Ultrason 12:349-52. 2010
    ..By becoming more experienced in abdominal ultrasonography, the visualization of the gastrointestinal tract will become easier...
  71. ncbi The prevalence of Helicobacter pylori infection in western Romania
    Ioan Sporea
    Department of Gastroenterology, University of Medicine and Pharmacy, Bd I Rebreanu no 156, 1900 Timisoara, Romania
    Rom J Gastroenterol 12:15-8. 2003
    ..The aim of this study was to evaluate the prevalence of Helicobacter Pylori (HP) infection in a representative group of workers in Timiş County...
  72. ncbi Ultrasound examination of normal gall bladder and biliary system
    Alina Popescu
    Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy Timisoara, Barbu Iscovescu str 8, ap 7, 300561 Timisoara, Romania
    Med Ultrason 12:150-2. 2010
    ..The gallbladder is evaluated by means of right subcostal oblique sections while for the hilum evaluation sections perpendicular on the ribs are used. The structures are assessed regarding their size, wall thickness and content...
  73. ncbi The prevalence of coeliac disease
    Ioan Sporea
    Rom J Gastroenterol 12:338; author reply 338-9. 2003