J Spence

Summary

Publications

  1. ncbi request reprint Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain
    J Spence
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell 102:67-76. 2000
  2. pmc A ubiquitin mutant with specific defects in DNA repair and multiubiquitination
    J Spence
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115
    Mol Cell Biol 15:1265-73. 1995

Detail Information

Publications2

  1. ncbi request reprint Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain
    J Spence
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell 102:67-76. 2000
    ..L28, like other ribosomal proteins, is metabolically stable. Therefore, these data suggest a regulatory role for multiubiquitin chains that is reversible and does not function to target the acceptor protein for degradation...
  2. pmc A ubiquitin mutant with specific defects in DNA repair and multiubiquitination
    J Spence
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115
    Mol Cell Biol 15:1265-73. 1995
    ..The results of this study suggest that Lys-63 is used as a linkage site in the formation of novel multiubiquitin chain structures that play an important role in DNA repair...