J Zarranz

Summary

Country: Spain

Publications

  1. ncbi request reprint The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
    Juan J Zarranz
    Department of Neurology, de Cruces Hospital, Departament of Neuroscience, University del Pais Vasco, Baracaldo, Vizcaya, Spain
    Ann Neurol 55:164-73. 2004
  2. pmc Phenotypic variability in familial prion diseases due to the D178N mutation
    J J Zarranz
    Neurology Service, Hospital Cruces, Department of Neurosciences, University of the Basque Country, 48903 Baracaldo, Vizcaya, Spain
    J Neurol Neurosurg Psychiatry 76:1491-6. 2005
  3. ncbi request reprint Tau-predominant-associated pathology in a sporadic late-onset Hallervorden-Spatz syndrome
    Juan J Zarranz
    Neurology Service, Hospital de Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Mov Disord 21:107-11. 2006
  4. ncbi request reprint Abnormal sleep architecture is an early feature in the E46K familial synucleinopathy
    Juan J Zarranz
    Neurology Service, Hospital of Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Mov Disord 20:1310-5. 2005
  5. ncbi request reprint A novel mutation (K317M) in the MAPT gene causes FTDP and motor neuron disease
    J J Zarranz
    Neurology Service, Department of Neurosciences, Hospital Cruces, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Neurology 64:1578-85. 2005
  6. ncbi request reprint [From empiricism to neuroscience in Alzheimer's disease]
    J Zarranz
    Departamento de Neurologia, Hospital de Cruces, Barakaldo, Vizcaya, Spain
    Rev Neurol 39:576-82. 2004
  7. ncbi request reprint Familial prion diseases in the Basque Country (Spain)
    Juan J Zarranz
    Service of Neurology, Hospital Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Spain
    Neuroepidemiology 24:103-9. 2005
  8. ncbi request reprint [Prevalence of dementia in the elderly aged above 65 in a district in the Basque Country]
    M Fernandez
    Hospital de Cruces, 48903 Baracaldo, Espana
    Rev Neurol 46:89-96. 2008
  9. ncbi request reprint Ancestral origins of the prion protein gene D178N mutation in the Basque Country
    Ana B Rodríguez-Martínez
    Unidad de Genómica Banco de ADN y Genotipado, Facultad de Farmacia, Universidad del Pais Vasco, Vitoria Gasteiz, Spain
    Hum Genet 117:61-9. 2005
  10. ncbi request reprint Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain
    María C González-Fernández
    Servicio General de Investigación Genómica, Banco de ADN and Departamento de Z y Biología Celular A, Universidad del Pais Vasco, Vitoria Gasteiz, Spain
    Parkinsonism Relat Disord 13:509-15. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
    Juan J Zarranz
    Department of Neurology, de Cruces Hospital, Departament of Neuroscience, University del Pais Vasco, Baracaldo, Vizcaya, Spain
    Ann Neurol 55:164-73. 2004
    ..Our data show that, in addition to the previously described hereditary alpha-synucleinopathies, dementia with Lewy bodies is related to mutation of alpha-synuclein...
  2. pmc Phenotypic variability in familial prion diseases due to the D178N mutation
    J J Zarranz
    Neurology Service, Hospital Cruces, Department of Neurosciences, University of the Basque Country, 48903 Baracaldo, Vizcaya, Spain
    J Neurol Neurosurg Psychiatry 76:1491-6. 2005
    ....
  3. ncbi request reprint Tau-predominant-associated pathology in a sporadic late-onset Hallervorden-Spatz syndrome
    Juan J Zarranz
    Neurology Service, Hospital de Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Mov Disord 21:107-11. 2006
    ....
  4. ncbi request reprint Abnormal sleep architecture is an early feature in the E46K familial synucleinopathy
    Juan J Zarranz
    Neurology Service, Hospital of Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Mov Disord 20:1310-5. 2005
    ..REM sleep behavior disorder could not be recorded in any case. Our findings expand the spectrum of sleep disorders reported in synucleinopathies whether sporadic or familial...
  5. ncbi request reprint A novel mutation (K317M) in the MAPT gene causes FTDP and motor neuron disease
    J J Zarranz
    Neurology Service, Department of Neurosciences, Hospital Cruces, University of the Basque Country, Baracaldo, Vizcaya, Spain
    Neurology 64:1578-85. 2005
    ..In some families the genetic basis is still unknown. The authors report two pedigrees with FTDP-17 harboring a novel mutation (K317M) in exon 11 in the MAPT gene...
  6. ncbi request reprint [From empiricism to neuroscience in Alzheimer's disease]
    J Zarranz
    Departamento de Neurologia, Hospital de Cruces, Barakaldo, Vizcaya, Spain
    Rev Neurol 39:576-82. 2004
    ..All the cases were grouped under the eponym of Alzheimer's disease and it is now being studied with the different modern scientific methods currently available to researchers...
  7. ncbi request reprint Familial prion diseases in the Basque Country (Spain)
    Juan J Zarranz
    Service of Neurology, Hospital Cruces, Department of Neurosciences, University of the Basque Country, Baracaldo, Spain
    Neuroepidemiology 24:103-9. 2005
    ..Further genetic and genealogical studies should resolve this issue...
  8. ncbi request reprint [Prevalence of dementia in the elderly aged above 65 in a district in the Basque Country]
    M Fernandez
    Hospital de Cruces, 48903 Baracaldo, Espana
    Rev Neurol 46:89-96. 2008
    ..To estimate the prevalence of dementia in the population aged above 65 in the district of Mungialde, Vizcaya...
  9. ncbi request reprint Ancestral origins of the prion protein gene D178N mutation in the Basque Country
    Ana B Rodríguez-Martínez
    Unidad de Genómica Banco de ADN y Genotipado, Facultad de Farmacia, Universidad del Pais Vasco, Vitoria Gasteiz, Spain
    Hum Genet 117:61-9. 2005
    ..We propose that "happy typing" constitutes an efficient method for determining disease-associated haplotypes, since the analysis of a single affected individual per pedigree should provide sufficient evidence...
  10. ncbi request reprint Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain
    María C González-Fernández
    Servicio General de Investigación Genómica, Banco de ADN and Departamento de Z y Biología Celular A, Universidad del Pais Vasco, Vitoria Gasteiz, Spain
    Parkinsonism Relat Disord 13:509-15. 2007
    ..Our findings highlight the importance of Lrrk2 parkinsonism in this population and may have important consequences for its extended Diaspora in North, Central and South Americas...
  11. ncbi request reprint Use of ziprasidone in parkinsonian patients with psychosis
    Juan Carlos Gómez-Esteban
    Neurology Service, Hospital of Cruces, Baracaldo, Vizcaya, Spain
    Clin Neuropharmacol 28:111-4. 2005
    ..Although controlled trials are needed, the findings suggest that ziprasidone may be effective in parkinsonian patients with psychosis...
  12. ncbi request reprint Parkinson's disease-like presentation of multiple system atrophy with poor response to STN stimulation: a clinicopathological case report
    Elena Lezcano
    Service of Neurology, Hospital of Cruces, Neurosciences Department, University of the Basque Country, Spain
    Mov Disord 19:973-7. 2004
    ..Because the subject complied with all the inclusion criteria (Core Assessment Program for Surgical Interventional Therapies in Parkinson's Disease), bilateral subthalamic nucleus deep brain stimulation electrodes were implanted...
  13. ncbi request reprint Restless legs syndrome in Parkinson's disease
    Juan C Gómez-Esteban
    Neurology Service, Movement Disorders Unit, Hospital Cruces, Baracaldo, Vizcaya
    Mov Disord 22:1912-6. 2007
    ..It would be advisable to validate the diagnostic criteria of RLS in this specific group of patients...
  14. doi request reprint Outcome of bilateral deep brain subthalamic stimulation in patients carrying the R1441G mutation in the LRRK2 dardarin gene
    Juan C Gómez-Esteban
    Movement Disorders Unit, Neurology Service, Cruces Hospital, Baracaldo, Vizcaya, Spain
    Neurosurgery 62:857-62; discussion 862-3. 2008
    ..The present study analyzes the postoperative outcome of deep brain subthalamic stimulation in patients carrying the R1441G mutation in the leucine-rich repeat kinase-2 (LRRK2) (dardarin) gene...