E F Wagner

Summary

Country: Spain

Publications

  1. pmc Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production
    Aline Bozec
    Genes, Development, and Disease Group, BBVA Foundation, Cancer Cell Biology Program, Spanish National Cancer Center, E 28029 Madrid, Spain
    J Cell Biol 190:1093-106. 2010
  2. doi request reprint Signal integration by JNK and p38 MAPK pathways in cancer development
    Erwin F Wagner
    Centro Nacional de Investigaciones Oncologicas, C Melchor Fernandez Almagro 3, Madrid 28029, Spain
    Nat Rev Cancer 9:537-49. 2009
  3. doi request reprint Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun)
    E F Wagner
    BBVA Foundation CNIO Cancer Cell Biology Program, Spanish National Cancer Centre CNIO, C Melchor Fernandez Almagro 3, E 28029 Madrid, Spain
    Ann Rheum Dis 69:i86-88. 2010
  4. doi request reprint Psoriasis: what we have learned from mouse models
    Erwin F Wagner
    Fundación Banco Bilbao Vizcaya Argentaria F BBVA CNIO Cancer Cell Biology Program, Centro Nacional de Investigaciones Oncologicas, Melchor Fernández Almargo 3, 29029 Madrid, Spain
    Nat Rev Rheumatol 6:704-14. 2010
  5. pmc Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis
    L Bakiri
    Genes, Development and Disease Group, F BBVA Cancer Cell Biology programme, National Cancer Research Centre CNIO, Madrid, Spain
    Oncogene 30:1506-17. 2011
  6. doi request reprint Targeting inflammation by modulating the Jun/AP-1 pathway
    Helia B Schonthaler
    Cancer Cell Biology Programme, Spanish National Cancer Research Centre CNIO, E 28029 Madrid, Spain
    Ann Rheum Dis 70:i109-12. 2011
  7. pmc Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis
    Helia B Schonthaler
    Banco Bilbao Vizcaya Argentaria BBVA Foundation, Cancer Cell Biology Programme, Centro Nacional de Investigaciones Oncologicas, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:21264-9. 2009

Collaborators

Detail Information

Publications7

  1. pmc Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production
    Aline Bozec
    Genes, Development, and Disease Group, BBVA Foundation, Cancer Cell Biology Program, Spanish National Cancer Center, E 28029 Madrid, Spain
    J Cell Biol 190:1093-106. 2010
    ..These findings reveal a novel function of Fra-2/AP-1 as a positive regulator of bone and matrix formation in mice and humans...
  2. doi request reprint Signal integration by JNK and p38 MAPK pathways in cancer development
    Erwin F Wagner
    Centro Nacional de Investigaciones Oncologicas, C Melchor Fernandez Almagro 3, Madrid 28029, Spain
    Nat Rev Cancer 9:537-49. 2009
    ..In this Review we highlight the recent progress made in defining the functions of the JNK and p38 MAPK pathways in different cancers...
  3. doi request reprint Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun)
    E F Wagner
    BBVA Foundation CNIO Cancer Cell Biology Program, Spanish National Cancer Centre CNIO, C Melchor Fernandez Almagro 3, E 28029 Madrid, Spain
    Ann Rheum Dis 69:i86-88. 2010
    ..Finally, the paper discusses the relevance of the Jun-dependent mouse model for psoriasis for preclinical studies in the field of anti-angiogenic therapies...
  4. doi request reprint Psoriasis: what we have learned from mouse models
    Erwin F Wagner
    Fundación Banco Bilbao Vizcaya Argentaria F BBVA CNIO Cancer Cell Biology Program, Centro Nacional de Investigaciones Oncologicas, Melchor Fernández Almargo 3, 29029 Madrid, Spain
    Nat Rev Rheumatol 6:704-14. 2010
    ..Indeed, a combination of genetic and immunological investigations will be necessary to develop both improved drugs for the treatment of psoriasis and novel curative strategies...
  5. pmc Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis
    L Bakiri
    Genes, Development and Disease Group, F BBVA Cancer Cell Biology programme, National Cancer Research Centre CNIO, Madrid, Spain
    Oncogene 30:1506-17. 2011
    ..Inhibition of Fos C-terminal phosphorylation on serine 362 by targeting RSK2 might be of therapeutic relevance for skin tumours...
  6. doi request reprint Targeting inflammation by modulating the Jun/AP-1 pathway
    Helia B Schonthaler
    Cancer Cell Biology Programme, Spanish National Cancer Research Centre CNIO, E 28029 Madrid, Spain
    Ann Rheum Dis 70:i109-12. 2011
    ..New targets identified in mouse models, together with investigations on human samples, will provide important new avenues for therapeutic interventions in psoriasis and other inflammatory skin diseases...
  7. pmc Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis
    Helia B Schonthaler
    Banco Bilbao Vizcaya Argentaria BBVA Foundation, Cancer Cell Biology Programme, Centro Nacional de Investigaciones Oncologicas, 28029 Madrid, Spain
    Proc Natl Acad Sci U S A 106:21264-9. 2009
    ..These results demonstrate that systemic blockade of VEGF by an inhibitory antibody might be used to treat patients who have inflammatory skin disorders such as psoriasis...