Adolfo Villa

Summary

Country: Spain

Publications

  1. pmc Phases I-III Clinical Trials Using Adult Stem Cells
    Ricardo Sanz-Ruiz
    Cardiology Department, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    Stem Cells Int 2010:579142. 2010
  2. ncbi request reprint [Angioplasty for acute coronary syndromes in the era of the stent]
    F F Avilés
    Instituto de Ciencias del Corazón de Valladolid ICICOR
    Rev Esp Cardiol 52:131-40. 1999
  3. ncbi request reprint [Continuous practice and advanced training in interventional cardiology. Recommendations for the assessment and maintenance of proficiency in interventional cardiology. A statement for physicians and advanced training units from the Section of Hemodynamic
    F Fernandez-Aviles
    Instituto de Ciencias del Corazón, Hospital Clinico Universitario de Valladolid
    Rev Esp Cardiol 53:1613-25. 2000
  4. ncbi request reprint Safety of coronary stenting early after thrombolysis in patients with acute myocardial infarction: one- and six-month clinical and angiographic evolution
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Catheter Cardiovasc Interv 55:467-76. 2002
  5. ncbi request reprint [Intracoronary stem cell transplantation in acute myocardial infarction]
    Francisco F Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid Spain
    Rev Esp Cardiol 57:201-8. 2004
  6. ncbi request reprint Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clínico Universitario C O Ramón y Cajal 3, E 47005 Valladolid, Spain
    Circ Res 95:742-8. 2004
  7. ncbi request reprint Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón, Hospital Universitario, Valladolid, Spain
    Lancet 364:1045-53. 2004
  8. ncbi request reprint Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial
    Francisco Fernandez-Aviles
    Servicio de Cardiologia, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007, Madrid, Spain
    Eur Heart J 28:949-60. 2007
  9. doi request reprint Comparison of neointimal hyperplasia with drug-eluting stents versus bare metal stents in patients undergoing intracoronary bone-marrow mononuclear cell transplantation following acute myocardial infarction
    Adolfo Villa
    Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Am J Cardiol 103:1651-6. 2009
  10. doi request reprint General overview of the Seventh International Symposium on Stem Cell Therapy and Cardiovascular Innovations
    Enrique Gutierrez
    Cardiology Department, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, Madrid, Spain
    J Cardiovasc Transl Res 4:115-20. 2011

Collaborators

  • Pedro L Sanchez
  • Roman Arnold
  • Ana Sanchez
  • Joaquin J Alonso
  • Maria E Fernandez
  • Paula Tejedor-Viñuela
  • Jaume Candell-Riera
  • Rafael Gabriel
  • C Michael Gibson
  • Hipólito Gutiérrez
  • Manuel Gómez-Bueno
  • F S Lozano
  • Ramon Garcia-Sanz
  • Francisco Fernandez-Aviles
  • Jose Alberto San Roman
  • Ana Revilla
  • Ricardo Sanz-Ruiz
  • Carolina Hernández
  • Enrique Gutierrez
  • Lucía Fernández
  • Marta Pinedo
  • Javier Lopez
  • Sandra Vázquez
  • Ma Eugenia Vázquez-Alvarez
  • Luis de la Fuente
  • Eugenia Fernández-Santos
  • Jose A San Roman
  • Hug Cuellar
  • Santiago Aguadé-Bruix
  • Javier Bermejo
  • Jose Ramon Gonzalez-Porras
  • Juan Alonso-Briales
  • Juan Lopez-Mesa
  • Alfonso Castro-Beiras
  • Jesus Blanco
  • Felipe Fernández-Vázquez
  • Oliver Gutierrez
  • Ricardo Sanz
  • Francisco F Aviles
  • Juan M Duran
  • Jose Lorenzo
  • Eugenia Vázquez Alvarez
  • María Eugenia Fernández Santos
  • Isaac Pascual
  • Enrique Gutiérrez Ibañes
  • Pedro L Sánchez Fernández
  • Adolfo Villa Arranz
  • Ma José Lorenzo
  • F Fernandez-Aviles
  • Marta Domínguez-Muñoa
  • Radoslaw Parma
  • F F Avilés
  • Jose Moreu
  • Rosa A Hernández
  • Gonzalo Pena
  • Maria Luz López
  • Ignacio Alberca
  • Jesus San Miguel
  • Ana Balanzategui
  • Javier García-Sancho
  • Mariano Valdes
  • Maria Jesus Penarrubia
  • Luis Martínez-Elbal
  • María J Peñarrubia
  • Javier García-Frade
  • Alberto Cantalapiedra
  • Isabel Calvo
  • Paula Tejedor
  • Javier Garcia Sancho
  • Jesús Fernández
  • Javier García Frade
  • Benigo Ramos
  • Nicolas Vazquez
  • Ana Serrador
  • Olga Sanz
  • Juan C Munoz
  • Federico Gimeno
  • Isabel Garcimartin
  • José Bermejo
  • Emilio Garcia-Moran
  • Benigno Ramos
  • E García Fernández
  • R Melgares Moreno
  • M Valdes Chavarri
  • J María Augé Sanpera
  • J Alonso Martin
  • C Macaya de Miguel
  • I Garcimartin
  • B Ramos
  • J M Duran

Detail Information

Publications26

  1. pmc Phases I-III Clinical Trials Using Adult Stem Cells
    Ricardo Sanz-Ruiz
    Cardiology Department, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    Stem Cells Int 2010:579142. 2010
    ....
  2. ncbi request reprint [Angioplasty for acute coronary syndromes in the era of the stent]
    F F Avilés
    Instituto de Ciencias del Corazón de Valladolid ICICOR
    Rev Esp Cardiol 52:131-40. 1999
    ..Until new data are available on these studies, the treatment of acute coronary ischemia should be tailored to each patient and no out-dated recommendation should be given or accepted...
  3. ncbi request reprint [Continuous practice and advanced training in interventional cardiology. Recommendations for the assessment and maintenance of proficiency in interventional cardiology. A statement for physicians and advanced training units from the Section of Hemodynamic
    F Fernandez-Aviles
    Instituto de Ciencias del Corazón, Hospital Clinico Universitario de Valladolid
    Rev Esp Cardiol 53:1613-25. 2000
    ..It also suggests that interventional cardiology should be considered as a subspecialty, of cardiology requiring specific credentials...
  4. ncbi request reprint Safety of coronary stenting early after thrombolysis in patients with acute myocardial infarction: one- and six-month clinical and angiographic evolution
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Catheter Cardiovasc Interv 55:467-76. 2002
    ..Thus, early posthrombolysis stenting is a safe strategy with a low reocclusion rate, which seems to allow functional recovery of the infarcted area. Further studies are necessary to define its impact on survival and cost-effectiveness...
  5. ncbi request reprint [Intracoronary stem cell transplantation in acute myocardial infarction]
    Francisco F Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid Spain
    Rev Esp Cardiol 57:201-8. 2004
    ..We have started a clinical study to demonstrate that the intracoronary implantation of stem cells is feasible and safe. The results in our first 5 patients are presented here...
  6. ncbi request reprint Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón ICICOR, Hospital Clínico Universitario C O Ramón y Cajal 3, E 47005 Valladolid, Spain
    Circ Res 95:742-8. 2004
    ..Large-scale randomized trials are needed now to assess the clinical efficacy of this treatment...
  7. ncbi request reprint Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial
    Francisco Fernandez-Aviles
    Instituto de Ciencias del Corazón, Hospital Universitario, Valladolid, Spain
    Lancet 364:1045-53. 2004
    ..The GRACIA-1 trial was designed to reassess the benefits of an early post-thrombolysis interventional approach in the era of stents and new antiplatelet agents...
  8. ncbi request reprint Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial
    Francisco Fernandez-Aviles
    Servicio de Cardiologia, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007, Madrid, Spain
    Eur Heart J 28:949-60. 2007
    ..We designed a non-inferiority, randomized, controlled study to evaluate whether lytic-based early routine angioplasty represents a reasonable reperfusion option for victims of STEMI irrespective of geographic or logistical barriers...
  9. doi request reprint Comparison of neointimal hyperplasia with drug-eluting stents versus bare metal stents in patients undergoing intracoronary bone-marrow mononuclear cell transplantation following acute myocardial infarction
    Adolfo Villa
    Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Am J Cardiol 103:1651-6. 2009
    ....
  10. doi request reprint General overview of the Seventh International Symposium on Stem Cell Therapy and Cardiovascular Innovations
    Enrique Gutierrez
    Cardiology Department, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, Madrid, Spain
    J Cardiovasc Transl Res 4:115-20. 2011
    ..The Symposium was dedicated to the memory of Professor Helmut Drexler...
  11. doi request reprint Absence of accelerated atherosclerotic disease progression after intracoronary infusion of bone marrow derived mononuclear cells in patients with acute myocardial infarction--angiographic and intravascular ultrasound--results from the TErapia Celular Apli
    Roman Arnold
    Institute of Heart Sciences ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Am Heart J 159:1154.e1-8. 2010
    ..Peripheral blood mononuclear cells or enriched CD133(+) BMMC have been associated with accelerated atherosclerosis of the distal segment of the infarct related artery (IRA)...
  12. doi request reprint Panoramic view of the Fifth International Symposium on Stem Cell Therapy and Applied Cardiovascular Biotechnology, April 2008, Madrid (Spain)
    Adolfo Villa
    Department of Cardiology, General University Hospital Gregorio Marañon, C Dr Esquerdo, 46, 28007 Madrid, Spain
    J Cardiovasc Transl Res 2:108-13. 2009
    ..In this article, we summarize some of the main topics of discussion, the state-of-the-art and latest advances in this field, and new challenges brought up for the near future...
  13. doi request reprint [Long-term changes in left ventricular function following intracoronary stem cell transplantation for acute myocardial infarction]
    Ana Revilla
    Unidad de Imagen Cardiaca ICICORELAB, Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Espana
    Rev Esp Cardiol 64:334-7. 2011
    ..Our findings indicate the improvement in injection fraction occurs soon after stem cell transplantation, within the first 6 months, and remains unchanged at long-term follow-up...
  14. doi request reprint Effect of Persistent Microvascular Obstruction on Post-infarction Ventricular Remodeling Following Intracoronary Bone-Marrow Cell Transplantation: A Contrast-Enhanced Cardiac Magnetic Resonance Study
    Adolfo Villa
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Rev Esp Cardiol (Engl Ed) 61:602-10. 2008
    ....
  15. doi request reprint Quantitative analysis of left ventricular function as a tool in clinical research. Theoretical basis and methodology
    Jose Alberto San Roman
    Servicio de Cardiologia, Hospital Clinico Universitario, Valladolid, Spain Unidad de Análisis de Imágenes Cardiacas de la Red de Enfermedades Cardiovasculares RECAVA, Spain
    Rev Esp Cardiol (Engl Ed) 62:535-51. 2009
    ..Finally, there is a discussion of how to select the best imaging technique for specific clinical applications. ..
  16. ncbi request reprint [Effect of persistent microvascular obstruction on post-infarction ventricular remodeling following intracoronary bone-marrow cell transplantation: a contrast-enhanced cardiac magnetic resonance study]
    Adolfo Villa
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Espana
    Rev Esp Cardiol 61:602-10. 2008
    ....
  17. ncbi request reprint Stem cell therapy in chronic ischemic heart dysfunction with and without viability
    Pedro L Sanchez
    Cardiology Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Cardiovasc Hematol Disord Drug Targets 10:167-72. 2010
    ..Viability assessment could help to find the best type of stem cell and the best method of cell delivery to be used in chronic ischemic heart dysfunction...
  18. ncbi request reprint Quantitative analysis of left ventricular function as a tool in clinical research. Theoretical basis and methodology
    Jose Alberto San Roman
    Servicio de Cardiologia, Hospital Clinico Universitario, Valladolid, Spain
    Rev Esp Cardiol 62:535-51. 2009
    ..Finally, there is a discussion of how to select the best imaging technique for specific clinical applications...
  19. ncbi request reprint General overview of the Sixth International Symposium on Stem Cell Therapy and Cardiovascular Innovations
    Ma Eugenia Vázquez-Alvarez
    Cardiology Department, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
    J Cardiovasc Transl Res 3:1-7. 2010
    ....
  20. doi request reprint Long-term changes in left ventricular function following intracoronary stem cell transplantation for acute myocardial infarction
    Ana Revilla
    Unidad de Imagen Cardiaca ICICORELAB, Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Rev Esp Cardiol (Engl Ed) 64:334-7. 2011
    ..Our findings indicate the improvement in injection fraction occurs soon after stem cell transplantation, within the first 6 months, and remains unchanged at long-term follow-up. ..
  21. ncbi request reprint Early translation of adipose-derived cell therapy for cardiovascular disease
    Ricardo Sanz-Ruiz
    Cardiology Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Cell Transplant 18:245-54. 2009
    ..In this review we discuss the basic principles of adipose-derived stem cells (types and characteristics, harvesting, and expansion), the initial experimental studies, and the currently ongoing clinical trials...
  22. ncbi request reprint Present and future of stem cells for cardiovascular therapy
    Pedro L Sanchez
    Servicio de Cardiologia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Ann Med 39:412-27. 2007
    ..In addition, we also speculate on the value of current clinical data to gain an insight into the mechanism of stem cell-based cardiac repair and to design clinical trials in the future...
  23. ncbi request reprint Launching a clinical program of stem cell therapy for cardiovascular repair
    Pedro L Sanchez
    Research Program at Cardiology Service, Hospital Universitario Gregorio Maranon, Madrid, Spain
    Nat Clin Pract Cardiovasc Med 4:S123-9. 2007
    ..Third, we present in depth the two most widely applicable delivery approaches. Finally, we discuss selection of patients and approaches and clinical and imaging methods by which to evaluate the safety and efficacy of this therapy...
  24. ncbi request reprint Contemplating the bright future of stem cell therapy for cardiovascular disease
    Pedro L Sanchez
    Institute of Heart Sciences ICICOR, Hospital Clinico Universitario, Valladolid, Spain
    Nat Clin Pract Cardiovasc Med 3:S138-51. 2006
    ..In the future, cardiovascular stem cell therapy may be administered to all patients. Here, we review what has happened and look at where we are going...
  25. ncbi request reprint Ventricular arrhythmias following intracoronary bone marrow stem cell transplantation
    Adolfo Villa
    Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario of Valladolid, Valladolid, Spain
    Europace 9:1222-3. 2007
    ..Therefore, our only aim when reporting our findings is to recommend a short but longer stay (2-3 days) following cell transplantation, particularly in patients with a natural tendency to develop arrhythmic events...
  26. ncbi request reprint Risk of recurrent venous thrombosis in patients with G20210A mutation in the prothrombin gene or factor V Leiden mutation
    Jose Ramon Gonzalez-Porras
    Department of Hematology, University Hospital of Salamanca, Spain
    Blood Coagul Fibrinolysis 17:23-8. 2006
    ..6% (95% confidence interval, 0.2-0.9). We have identified a group of patients with DVT but at very low risk of re-thrombosis in whom an extended secondary thromboprophylaxis should be carefully considered...