Research Topics
| Adolfo VillaSummaryCountry: Spain Publications
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Detail Information
Publications
[Angioplasty for acute coronary syndromes in the era of the stent]F F Avilés
Instituto de Ciencias del Corazón de Valladolid ICICOR
Rev Esp Cardiol 52:131-40. 1999..Until new data are available on these studies, the treatment of acute coronary ischemia should be tailored to each patient and no out-dated recommendation should be given or accepted...- Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trialFrancisco Fernandez-Aviles
Instituto de Ciencias del Corazón, Hospital Universitario, Valladolid, Spain
Lancet 364:1045-53. 2004..The GRACIA-1 trial was designed to reassess the benefits of an early post-thrombolysis interventional approach in the era of stents and new antiplatelet agents... - Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarctionFrancisco Fernandez-Aviles
Instituto de Ciencias del Corazón ICICOR, Hospital Clínico Universitario C O Ramón y Cajal 3, E 47005 Valladolid, Spain
Circ Res 95:742-8. 2004..Large-scale randomized trials are needed now to assess the clinical efficacy of this treatment... - [Intracoronary stem cell transplantation in acute myocardial infarction]Francisco F Aviles
Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid Spain
Rev Esp Cardiol 57:201-8. 2004..We have started a clinical study to demonstrate that the intracoronary implantation of stem cells is feasible and safe. The results in our first 5 patients are presented here... - Safety of coronary stenting early after thrombolysis in patients with acute myocardial infarction: one- and six-month clinical and angiographic evolutionFrancisco Fernandez-Aviles
Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Spain
Catheter Cardiovasc Interv 55:467-76. 2002..Thus, early posthrombolysis stenting is a safe strategy with a low reocclusion rate, which seems to allow functional recovery of the infarcted area. Further studies are necessary to define its impact on survival and cost-effectiveness... - [Continuous practice and advanced training in interventional cardiology. Recommendations for the assessment and maintenance of proficiency in interventional cardiology. A statement for physicians and advanced training units from the Section of HemodynamicF Fernandez-Aviles
Instituto de Ciencias del Corazón, Hospital Clinico Universitario de Valladolid
Rev Esp Cardiol 53:1613-25. 2000..It also suggests that interventional cardiology should be considered as a subspecialty, of cardiology requiring specific credentials... - Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trialFrancisco Fernandez-Aviles
Servicio de Cardiologia, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007, Madrid, Spain
Eur Heart J 28:949-60. 2007..We designed a non-inferiority, randomized, controlled study to evaluate whether lytic-based early routine angioplasty represents a reasonable reperfusion option for victims of STEMI irrespective of geographic or logistical barriers... 
Comparison of neointimal hyperplasia with drug-eluting stents versus bare metal stents in patients undergoing intracoronary bone-marrow mononuclear cell transplantation following acute myocardial infarctionAdolfo Villa
Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Am J Cardiol 103:1651-6. 2009....- Absence of accelerated atherosclerotic disease progression after intracoronary infusion of bone marrow derived mononuclear cells in patients with acute myocardial infarction--angiographic and intravascular ultrasound--results from the TErapia Celular ApliRoman Arnold
Institute of Heart Sciences ICICOR, Hospital Clinico Universitario, Valladolid, Spain
Am Heart J 159:1154.e1-8. 2010..Peripheral blood mononuclear cells or enriched CD133(+) BMMC have been associated with accelerated atherosclerosis of the distal segment of the infarct related artery (IRA)... - General overview of the Seventh International Symposium on Stem Cell Therapy and Cardiovascular InnovationsEnrique Gutierrez
Cardiology Department, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, Madrid, Spain
J Cardiovasc Transl Res 4:115-20. 2011..The Symposium was dedicated to the memory of Professor Helmut Drexler... - [Long-term changes in left ventricular function following intracoronary stem cell transplantation for acute myocardial infarction]Ana Revilla
Unidad de Imagen Cardiaca ICICORELAB, Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Espana
Rev Esp Cardiol 64:334-7. 2011..Our findings indicate the improvement in injection fraction occurs soon after stem cell transplantation, within the first 6 months, and remains unchanged at long-term follow-up... - Stem cell therapy in chronic ischemic heart dysfunction with and without viabilityPedro L Sanchez
Cardiology Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Cardiovasc Hematol Disord Drug Targets 10:167-72. 2010..Viability assessment could help to find the best type of stem cell and the best method of cell delivery to be used in chronic ischemic heart dysfunction... - General overview of the Sixth International Symposium on Stem Cell Therapy and Cardiovascular InnovationsMa Eugenia Vázquez-Alvarez
Cardiology Department, Hospital General Universitario Gregorio Maranon, Doctor Esquerdo 46, 28007 Madrid, Spain
J Cardiovasc Transl Res 3:1-7. 2010.... - Quantitative analysis of left ventricular function as a tool in clinical research. Theoretical basis and methodologyJose Alberto San Roman
Servicio de Cardiologia, Hospital Clinico Universitario, Valladolid, Spain
Rev Esp Cardiol 62:535-51. 2009..Finally, there is a discussion of how to select the best imaging technique for specific clinical applications... - [Effect of persistent microvascular obstruction on post-infarction ventricular remodeling following intracoronary bone-marrow cell transplantation: a contrast-enhanced cardiac magnetic resonance study]Adolfo Villa
Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario, Valladolid, Espana
Rev Esp Cardiol 61:602-10. 2008.... - Present and future of stem cells for cardiovascular therapyPedro L Sanchez
Servicio de Cardiologia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Ann Med 39:412-27. 2007..In addition, we also speculate on the value of current clinical data to gain an insight into the mechanism of stem cell-based cardiac repair and to design clinical trials in the future... - Launching a clinical program of stem cell therapy for cardiovascular repairPedro L Sanchez
Research Program at Cardiology Service, Hospital Universitario Gregorio Maranon, Madrid, Spain
Nat Clin Pract Cardiovasc Med 4:S123-9. 2007..Third, we present in depth the two most widely applicable delivery approaches. Finally, we discuss selection of patients and approaches and clinical and imaging methods by which to evaluate the safety and efficacy of this therapy... - Contemplating the bright future of stem cell therapy for cardiovascular diseasePedro L Sanchez
Institute of Heart Sciences ICICOR, Hospital Clinico Universitario, Valladolid, Spain
Nat Clin Pract Cardiovasc Med 3:S138-51. 2006..In the future, cardiovascular stem cell therapy may be administered to all patients. Here, we review what has happened and look at where we are going... - Early translation of adipose-derived cell therapy for cardiovascular diseaseRicardo Sanz-Ruiz
Cardiology Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Cell Transplant 18:245-54. 2009..In this review we discuss the basic principles of adipose-derived stem cells (types and characteristics, harvesting, and expansion), the initial experimental studies, and the currently ongoing clinical trials... - Ventricular arrhythmias following intracoronary bone marrow stem cell transplantationAdolfo Villa
Instituto de Ciencias del Corazón ICICOR, Hospital Clinico Universitario of Valladolid, Valladolid, Spain
Europace 9:1222-3. 2007..Therefore, our only aim when reporting our findings is to recommend a short but longer stay (2-3 days) following cell transplantation, particularly in patients with a natural tendency to develop arrhythmic events... - Risk of recurrent venous thrombosis in patients with G20210A mutation in the prothrombin gene or factor V Leiden mutationJose Ramon Gonzalez-Porras
Department of Hematology, University Hospital of Salamanca, Spain
Blood Coagul Fibrinolysis 17:23-8. 2006..6% (95% confidence interval, 0.2-0.9). We have identified a group of patients with DVT but at very low risk of re-thrombosis in whom an extended secondary thromboprophylaxis should be carefully considered...