Research Topics
| Xavier VidalSummaryCountry: Spain Publications
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Publications
Risk of upper gastrointestinal bleeding and the degree of serotonin reuptake inhibition by antidepressants: a case-control studyXavier Vidal
Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Passeig Vall d Hebron 129 139, Barcelona, Spain
Drug Saf 31:159-68. 2008..We present the results related to the use of antidepressants by the degree of serotonin reuptake inhibition they induce, the selectivity at monoamine transporters and the dose...
Epidemiology of aplastic anemia: a prospective multicenter studyEva Montané
Fundacio Institut Catala de Farmacologia, Barcelona, Spain
Haematologica 93:518-23. 2008..Aplastic anemia is a rare and severe disease. Its incidence varies considerably worldwide. We aimed at describing the epidemiology of this disease, including the incidence, mortality and survival trends, in a well-defined population...
Population-based drug-induced agranulocytosisLuisa Ibáñez
Fundacio Institut Catala de Farmacologia, Universitat Autonoma de Barcelona, Clinical Pharmacology Service, Hospital Universitari Vall d Hebron, Barcelona, Spain
Arch Intern Med 165:869-74. 2005..Since the publication of a major international case-control study on the risk of agranulocytosis associated with the use of medicines in the 1980s, many new drugs have been introduced in therapeutics...
Case-control study of regular analgesic and nonsteroidal anti-inflammatory use and end-stage renal diseaseLuisa Ibáñez
Fundacio Institut Catala de Farmacologia, Universitat Autonoma de Barcelona, Hospital Vall d Hebron, Barcelona, Spain
Kidney Int 67:2393-8. 2005..In order to examine this association, a case-control study with incident cases of ESRD was carried out...
Upper gastrointestinal bleeding associated with the use of NSAIDs: newer versus older agentsJoan Ramon Laporte
Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Barcelona, Spain
Drug Saf 27:411-20. 2004..The aim of this study was to estimate the risk of upper gastrointestinal bleeding associated with NSAIDs and analgesics, with special emphasis on those agents that have been introduced in recent years...
Efficacy of psychostimulant drugs for cocaine dependenceXavier Castells
Department of Psychiatry, Hospital Universitari Vall d Hebron and Department of Pharmacology, Therapeutics and Toxicology, , Barcelona, Catalonia, Spain
Cochrane Database Syst Rev 2:CD007380. 2010..Nevertheless promising results exist for methadone maintained dual heroin-cocaine addicts and for some specific drugs such as dexamphetamine and bupropion...
An intervention to improve spontaneous adverse drug reaction reporting by hospital physicians: a time series analysis in SpainConsuelo Pedrós
Fundacio Institut Catala de Farmacologia, Barcelona, Spain
Drug Saf 32:77-83. 2009..Spontaneous reporting of adverse drug reactions (ADRs) in hospitals is scarce and several obstacles to such reporting have been identified previously...
Efficacy of methylphenidate for adults with attention-deficit hyperactivity disorder: a meta-regression analysisXavier Castells
Psychiatry Department, Hospital Universitari Vall dHebron, Barcelona, Spain
CNS Drugs 25:157-69. 2011..The reasons for this variability have not been comprehensively investigated...
Reporting randomised clinical trials of analgesics after traumatic or orthopaedic surgery is inadequate: a systematic reviewEva Montané
Fundacio Institut Catala de Farmacologia, Clinical Pharmacology Service, Hospital Universitari Vall d Hebron, Pg Vall d Hebron, no 119 129, 08035 Barcelona, Universitat Autonoma de Barcelona, Spain
BMC Clin Pharmacol 10:2. 2010..We aimed to examine the quality of reporting RCTs on analgesics for postoperative pain after TOS...
Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: A systematic review and meta-analysis of controlled clinical trialsXavier Castells
Psychiatry Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Am J Drug Alcohol Abuse 35:339-49. 2009..To determine the efficacy of Opiate Maintenance Therapy (OMT) and adjunctive interventions for dual heroin and cocaine dependence by means of a meta-analysis...
Agranulocytosis associated with dipyrone (metamizol)Luisa Ibáñez
Fundacio Institut Catala de Farmacologia, WHO Collaborating Centre for Research and Training in Pharmacoepidemiology, Department of Pharmacology, Therapeutics and Toxicology, Institut Catala de la Salut, Universitat Autonoma de Barcelona, Barcelona, Spain
Eur J Clin Pharmacol 60:821-9. 2005..Reported estimates of the risk of agranulocytosis associated with metamizol have varied by several orders of magnitude. We assessed this association in a large database for the surveillance of blood dyscrasias...
Efficacy of indirect dopamine agonists for psychostimulant dependence: a systematic review and meta-analysis of randomized controlled trialsClara Pérez-Mañá
Unit of Human Pharmacology and Neurosciences, Institut de Recerca de l Hospital del Mar, IMIM Parc de Salut Mar, Barcelona, Spain
J Subst Abuse Treat 40:109-22. 2011..IDAs appear to be efficacious for reducing psychostimulant use but did not improve retention. Efforts should be undertaken to reduce the risk of bias of clinical trials with psychostimulant-dependent individuals...
Case-population studies in pharmacoepidemiologyDolors Capellà
Fundacio Institut Catala de Farmacologia, Universitat Autonoma de Barcelona, CSU Vall d Hebron, Pg Vall d Hebron 119 129, Barcelona 08035, Spain
Drug Saf 25:7-19. 2002..Case-population studies can give approximate risk estimates, but the method should be validated by comparing its results with those of case-control studies...
Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: epidemiological and clinical features, and exposure to drugsLuisa Ibáñez
Fundacio Institut Catala de Farmacologia, Barcelona, Spain
J Hepatol 37:592-600. 2002..Many drugs have been implicated. Data on its epidemiology are scarce. We performed a population-based prospective study of acute serious liver disease in Catalonia (Spain)...
Adverse effects of ACE inhibitors in patients with chronic heart failure and/or ventricular dysfunction : meta-analysis of randomised clinical trialsAntonia Agustí
Fundació Institut Català de Farmacologia Servei de Farmacologia Clínica, Hospital Universitari Vall d Hebron, and Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Barcelona, Spain
Drug Saf 26:895-908. 2003..However, there is little systematic information on the tolerability and adverse effects associated with their use in these conditions...
Pregnancy after treatment of breast cancer in young women does not adversely affect the prognosisOctavi Córdoba
Breast Cancer Unit, Service of Gynecology, Hospital Vall d Hebron, Barcelona, Spain
Breast 21:272-5. 2012..009). Breast cancer patients presented a high number of unwanted pregnancies. Pregnancy after breast cancer not only did not adversely affect prognosis of the neoplasm but also may have a protective effect...
Pretransplantation liver function impacts on the outcome of allogeneic hematopoietic stem cell transplantation: a study of 455 patientsPere Barba
Hematology Departments of Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona and Universitat Autònoma de Barcelona, Mas Casanovas 90, Barcelona, Spain
Biol Blood Marrow Transplant 17:1653-61. 2011..In conclusion, hepatic dysfunction before allo-SCT is frequent and has an impact on transplantation outcomes. The best indicator of liver dysfunction still has to be determined...
Paracetamol in therapeutic dosages and acute liver injury: causality assessment in a prospective case seriesMònica Sabaté
Fundacio Institut Catala de Farmacologia, Universitat Autonoma de Barcelona, Hospital Universitari Vall d Hebron, Barcelona, Spain
BMC Gastroenterol 11:80. 2011..The aim is to describe the characteristics of patients admitted to hospital with jaundice who had previous exposure to therapeutic doses of paracetamol. An assessment of the causality role of paracetamol was performed in each case...
Efficacy of central nervous system stimulant treatment for cocaine dependence: a systematic review and meta-analysis of randomized controlled clinical trialsXavier Castells
Psychiatry Service, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Catalonia, Spain
Addiction 102:1871-87. 2007..To evaluate the efficacy of central nervous system (CNS) stimulants compared with placebo for the treatment of cocaine dependence...
Predictors of mortality and impact of aminoglycosides on outcome in listeriosis in a retrospective cohort studyOriol Mitjà
Department of Infectious Diseases, Hospital Universitari Vall d Hebron, Universitat Autonoma, Barcelona, Spain
J Antimicrob Chemother 64:416-23. 2009..The aim of this study was to evaluate predictors of mortality and the impact of aminoglycosides on outcome in patients with listeriosis...
Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomitingMarta Duran
Fundacio Institut Catala de Farmacologia, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
Br J Clin Pharmacol 70:656-63. 2010....
