Research Topics
| Alfonso VegaSummaryCountry: Spain Publications
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Publications
Incidental detection of oncocytosis in a renal biopsy specimen for idiopathic nephrotic syndromeJ Fernando Val-Bernal
Department of Anatomic Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Avda Valdecilla s n, ES 39011 Santander, Spain
Pathol Res Pract 207:733-6. 2011..As far as we are aware, renal oncocytosis incidentally discovered in a biopsy performed for the diagnosis of a medical disease of the kidney has not been reported...
Pyogenic granuloma of the large intestine: Case report and review of reported cases in the adultJose Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain Electronic address
Pathol Res Pract 208:687-90. 2012..In large or deep lesions, a surgical excision may be necessary. Pathologists should be familiar with this condition so as to avoid overdiagnosis as a malignant vascular tumor...
Sclerotic fibroma (storiform collagenoma)-like stroma in a fibroadenoma of axillary accessory breast tissueJose Fernando Val-Bernal
Anatomical Pathology Department, Marques de Valdecilla, University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain
J Cutan Pathol 39:798-802. 2012..The lesion should be differentiated from extraneural perineuroma, from the changes in fibroadenomas in Cowden's syndrome, from sclerosing lobular hyperplasia (fibroadenomatoid mastopathy) and from pseudoangiomatous stromal hyperplasia...
Simultaneous papillary fibroelastomas of the pulmonary and aortic valvesJ Fernando Val-Bernal
Service of Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain
Pathol Res Pract 208:315-7. 2012..All surgically removed valvular lesions should be histopathologically examined to confirm the echocardiographic diagnosis...
Bilateral xanthogranulomatous orchitis in a tetraplegic patientJ Fernando Val-Bernal
Pathology Department, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain
Pathol Res Pract 208:62-4. 2012..Since tissue destruction is a feature of this process, curative treatment required antibiotic therapy followed by bilateral excision of testes and epididymes...
Prichard's structures of the fossa ovalis are age-related phenomena composed of nonreplicating endothelial cells: the cardiac equivalent of cutaneous senile angiomaJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
APMIS 115:1234-40. 2007..We propose that Prichard's structures are the cardiac equivalent of cutaneous senile angioma...
Pilonidal sinus associated with cellular blue nevus. A previously unrecognized associationJose Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
J Cutan Pathol 34:942-5. 2007..Differential diagnoses included atypical CBN, borderline melanocytic tumor and malignant melanoma. Radical excision provides a good prognosis for the rare association consisting of a common disease such as PS with the uncommon CBN...
Subcutaneous ossifying lipoma: case report and review of the literatureJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Avenida Valdecilla s n, E 39008 Santander, Spain
J Cutan Pathol 34:788-92. 2007..Lipomas can undergo a variety of changes, one of which is ossification. Ossifying lipoma (OL), independent of bone tissue, is rare. No case has been reported with this heading in the dermatopathological literature...
Extragenital subcutaneous cellular angiofibroma. Case reportJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
APMIS 115:254-8. 2007..Extragenital CAF, except for location, shows similar clinicopathological features to genital CAF. Simple tumorectomy appears to be adequate treatment. Morphologically, CAF is closely related to spindle cell lipoma...
Lingual subgemmal neurogenous plaques with pseudoepitheliomatous hyperplasia: incidental pseudomalignant conditionJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 56:462-5. 2006..Awareness of the morphological spectrum of subgemmal neurogenous plaques can avoid the overdiagnosis of these lesions as neural tumors or squamous cell carcinoma...
Ectopic epididymal tissue in appendix testisJ Fernando Val-Bernal
Departamento de Anatomia Patologica, Hospital Universitario Marques de Valdecilla, Universidad de Cantabria, Avda Valdecilla s n, ES 39008, Santander, Spain
Virchows Arch 449:373-5. 2006..Awareness of this aberrant tissue avoids misinterpretation as a transected functional reproductive structure...
Pedunculated polypoid lymphangioma of the anal canalJose Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 58:442-4. 2008..7 x 1.3 x 1 cm in a 40-year-old woman. A pedicle does not exclude the endoscopic diagnosis of lymphangioma. Lymphangioma must be included in the differential diagnosis of polypoid lesions of the anal canal...
Localized eosinophilic (Langerhans' cell) granuloma of the lower lip. A lesion that may cause diagnostic errorJose Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
J Cutan Pathol 36:1109-13. 2009..Labial eosinophilic (Langerhans' cell) granuloma should be considered in the histological differential diagnosis in cases with atypical polymorphous infiltrates including large pale cells...
Clinically unapparent melanocytic nevi on the prepuceJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
J Cutan Pathol 36:444-7. 2009..Melanocytic nevi from the genitalia are uncommon. Nevi on the vulva are much better described than nevi on male genitalia. To our knowledge, a systematic study of preputial melanocytic nevi has not been reported...
Concurrent xanthogranulomatous orchiepididymitis and seminoma in the same testisJ Fernando Val-Bernal
Department of Anatomical Pathology, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 60:55-8. 2010..Pathologists should be aware of this concurrence of lesions to avoid potential misdiagnosis. Wide sampling of the orchidectomy specimens with XGO is mandatory to exclude an occult seminoma...
Non-compaction of the ventricular myocardium: a cardiomyopathy in search of a pathoanatomical definitionJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Histol Histopathol 25:495-503. 2010..It is likely that surgical pathologists will find this entity more frequently due to involvement in transplantation teams...
Nodular spindle cell proliferation in the wall of a varicose vein mimicking Kaposi's sarcomaJose Fernando Val-Bernal
Anatomical Pathology Department, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
J Cutan Pathol 38:376-80. 2011....
The nipple-areola complex epidermis: a prospective systematic study in adult autopsiesJose Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, University of Cantabria, Santander, Spain
Am J Dermatopathol 32:787-93. 2010..05). The prevalence of these mites was seen to remain steady along the years since the third decade. Demodex mites are common parasites of human nipple and are apparently of no pathologic significance...
Mucin-producing renal oncocytoma. An undescribed variant of oncocytomaJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Res Pract 207:271-4. 2011....
Incidental in vivo detection of an isolated hemangioma of the aortic valve in a man with a history of renal transplantationJ Fernando Val-Bernal
Departamento de Anatomia Patologica, Hospital Universitario Marques de Valdecilla, Avda Valdecilla 1, Santander 39008, Spain
Virchows Arch 449:121-3. 2006..In 50% of cases the hemangioma is an incidental finding at autopsy or in a removed valve. Valve aortic hemangioma, despite its rarity, should be considered in the differential diagnosis of vascular lesions of this cardiac valve...
Isolated (localized) idiopathic granulomatous (giant cell) vasculitis in an intramuscular lipomaJ Fernando Val-Bernal
Department of Anatomical Pathology, Medical Faculty, Marques de Valdecilla University Hospital, University of Cantabria, Avda Valdecilla 1, ES 39008 Santander, Spain
Pathol Res Pract 202:171-6. 2006..It is important to distinguish cases of isolated intratumorous IGV from systemic disease, because the latter implies a poor prognosis and requires an aggressive treatment...
Pneumopolycystic endometritisJ Fernando Val-Bernal
Department of Anatomic Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Am J Surg Pathol 30:258-61. 2006..Recognition of pneumopolycystic endometritis is important because this condition does not represent an aggressive life-threatening infection, and spontaneous resolution is to be expected...
Cutaneous lipomatous neurofibromaJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Am J Dermatopathol 24:246-50. 2002..This acquired lesion could arise from local stem cells. The old suggestion that neuroectoderm is capable of mesenchymal differentiation may be relevant to the histogenesis of this neoplasm...
Incidental localized (solitary) epithelial mesothelioma of the pericardium: case report and literature reviewJ Fernando Val-Bernal
Department of Anatomical Pathology, Marqués de Vadecilla University Hospital, Medical Faculty, University of Cantabria, Avda Vadecilla 1, E 39008 Santander, Spain
Cardiovasc Pathol 11:181-5. 2002..Nevertheless, in contrast to diffuse tumors, complete surgical excision may be curative. Differential diagnosis includes solitary fibrous tumor, synovial sarcoma, epithelioid angiosarcoma, and adenomatoid tumor of the pericardium...
Concurrent tubulovillous adenoma and transitional cell carcinoma associated with diffuse gastric and intestinal metaplasia of the defunctioned ureterJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Res Pract 197:507-13. 2001..The patient died 76 days after admission. The dismal prognosis of our case was determined by the advanced anatomical stage and the histological high grade of the transitional cell carcinoma of the ureter...
Pagetoid dyskeratosis is a frequent incidental finding in hemorrhoidal diseaseJ F Val-Bernal
Departamento de Anatomia Patologica, Hospital Universitario Marques de Valdecilla, Avda Valdecilla 1, E 39008 Santander, Spain
Arch Pathol Lab Med 125:1058-62. 2001..It has been suggested that friction is the most probable inductor of the lesion. To the best of our knowledge, pagetoid cells have not been reported in surgically resected hemorrhoids...
Cardiac epithelioid angiosarcoma presenting as cutaneous metastasesJ F Val-Bernal
Department of Anatomical Pathology, and Service of Oncology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
J Cutan Pathol 28:265-70. 2001..The tumor may present abruptly with a fulminant clinical course. Initial presentation with metastatic disease is rare. Only one case has been reported of a patient who presented with cutaneous metastases...
Papillary adenoma of the kidney with mucinous secretionJ F Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Histol Histopathol 16:387-92. 2001..Mucin production suggests that renal papillary adenoma and papillary renal cell carcinoma are actually not two independent biological processes, but a continuum of one biological process...
Pagetoid dyskeratosis of the cervix: an incidental histologic finding in uterine prolapseJ F Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Am J Surg Pathol 24:1518-23. 2000..The pathologist should be aware of the histologic features of pagetoid dyskeratosis in the ectocervix to avoid misdiagnosis and unnecessary treatment. Routine histologic study is usually sufficient to identify the lesion...
Association of cystic nephroma with angiomyolipoma in the same kidneyJ F Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Res Pract 196:583-8. 2000..To the best of our knowledge, this combination of neoplasms has not yet been described before. This rare situation emphasizes the need for careful diagnosis and the correct management of coincident renal neoplasms...
Polypoid (pedunculated) subepicardial lipoma: a cardiac lesion resembling the epiploic appendageJ F Val-Bernal
Anatomical Pathology Department, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Cardiovasc Pathol 9:55-7. 2000..The lipoma was an incidental finding at autopsy. The twisted lesion showed many similarities with the infarcted epiploic appendages observed in the visceral peritoneum...
Symptomatic solitary right renal vein aneurysm: a case reportJ F Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Cardiovasc Pathol 9:29-32. 2000..Renal venography is indicated for the diagnosis of these lesions...
Fibroepithelioma of pinkus with tumor giant cellsJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Am J Dermatopathol 24:336-9. 2002..In fibroepithelioma of Pinkus, the correct diagnosis depends primarily on the architectural pattern of the tumor rather than on its cytologic features...
Churg-Strauss syndrome and sudden cardiac deathJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Cardiovasc Pathol 12:94-7. 2003..This variant of the syndrome may be fulminant and present as sudden cardiac death. This form can only be elucidated by autopsy study...
Incidental detection of an asymptomatic papillary fibroelastoma on a control biopsy of a heart transplant recipientJ Fernando Val-Bernal
Department of Anatomical Pathology, Medical Faculty, Marques de Valdecilla University Hospital, University of Cantabria, ES 39008 Santander, Spain
Cardiovasc Pathol 14:280-2. 2005..Papillary fibroelastoma (PFE) of the right ventricle is a rare lesion. This tumor has not been described in the heart of a cardiac transplant recipient...
Anticipated diagnosis of left atrial myxoma following histological investigation of limb embolectomy specimens: a report of two casesJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 53:489-94. 2003..Calretinin is a useful marker in the differential diagnosis of cardiac myxoma with a myxoid thrombus. The necessity of histological examination of the embolectomy material is stressed...
Isolated non-compaction of the left ventricular myocardium in an adult treated with heart transplantationJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 56:35-9. 2006..It is likely that surgical pathologists will encounter this entity more frequently due to involvement in transplantation teams...
Soft-tissue angiomatosis in adulthood: a case in the forearm showing a prominent myxoid adipose tissue component mimicking liposarcomaJ Fernando Val-Bernal
Department of Anatomic Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 55:155-9. 2005..In conclusion, angiomatosis might simulate liposarcoma, particularly if the mass is large, heterogeneous, myxoid and appears later in life...
Cutaneous lipomatous neurofibroma: characterization and frequencyJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, University of Cantabria, Santander, Spain
J Cutan Pathol 32:274-9. 2005..There are numerous variants of cutaneous neurofibroma reflecting its manner of growth and histologic composition. Lipomatous neurofibroma is the latest described variant with only eight cases reported...
Incidental in vivo detection of an epithelioid hemangioendothelioma of the mitral valveJ Fernando Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 55:644-8. 2005..Although EHE can present a histologically benign appearance, the correct pathological diagnosis is clinically important because the lesion can be potentially malignant. Regular follow up is suggested due to this potential...
Myxoma of the renal capsuleJ Fernando Val-Bernal
Department of Anatomical Pathology, Medical Faculty, University of Cantabria, Marques de Valdecilla University Hospital, Santander, Spain
Pathol Res Pract 200:835-40. 2005..It is important to consider a renal capsular myxoma when examining lesions at this anatomic site to avoid misdiagnoses and to ensure that the patient receives appropriate treatment and prognostic information...
Postoperative spindle cell nodule of the breast: Pseudosarcomatous myofibroblastic proliferation following endo-surgeryMaria Francisca Garijo
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain
Pathol Int 58:787-91. 2008..Recognition of this reactive lesion will avoid overdiagnosis of spindle cell malignant tumor. Attention to clinicopathological and histological features should result in accurate recognition of this lesion...
Surgery of cosmetic sequelae after breast-conserving therapySara Regaño
Hospital Marques de Valdecilla, Breast Surgery Unit, University of Cantabria, Santander, Spain
Breast J 16:389-93. 2010....
Needle-wire-guided breast tumor excisionFernando Hernanz
University of Cantabria, Breast Unit, Cardenal Herrera Oria, 39011 Santander, Cantabria, Spain
J Surg Oncol 94:165-6. 2006..Needles are used as markers showing optimal excision margins, especially at conflicting points...
Image of the month. Mammary hamartomaFernando Hernanz
Division of General Surgery, , Facultad de Medicina, Universidad de Cantabria, Santander, Spain
Arch Surg 142:201-2. 2007
Reduction mammaplasty: an advantageous option for breast conserving surgery in large-breasted patientsFernando Hernanz
Department of Surgery, University of Cantabria, Santander, Spain
Surg Oncol 19:e95-e102. 2010....
C4d immunohistochemical staining is a sensitive method to confirm immunoreactant deposition in formalin-fixed paraffin-embedded tissue in membranous glomerulonephritisJ F Val-Bernal
Department of Anatomical Pathology, Marques de Valdecilla University Hospital, University of Cantabria, Santander, Spain
Histol Histopathol 26:1391-7. 2011..C4d immunostaining, using an IP method, deserves a place as an adjunct method in the biopsy diagnosis of MGN...
Giant hamartoma of the breast treated by the mammaplasty approachFernando Hernanz
ANZ J Surg 78:216-7. 2008
