Research Topics
Species | R M TorderaSummaryAffiliation: University of Navarra Country: Spain Publications
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Detail Information
Publications
Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1)R M Tordera
Department of Pharmacology, University of Navarra, 31080 Pamplona, Spain
Eur J Neurosci 25:281-90. 2007..These observations suggest that a VGLUT1-mediated presynaptic alteration of the glutamatergic synapses, in specific brain regions, leads to a behavioural phenotype resembling certain aspects of psychiatric and cognitive disorders...
Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortexR M Tordera
Department of Pharmacology, University of Navarra, 31080 Pamplona, Spain
Eur Neuropsychopharmacol 21:23-32. 2011..We suggest that these genes could form part of the altered "molecular context" underlying depressive-like behaviour in animal models. The clinical relevance of these findings is discussed...
Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatmentN Elizalde
Department of Pharmacology, University of Navarra, 31080, Pamplona, Spain
Psychopharmacology (Berl) 199:1-14. 2008..In this study, we investigate acute and long-term effects of CMS and antidepressant treatment on depressive, anxiety-like behavior and learning...
Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factorsE Venzala
Department of Pharmacology, University of Navarra, 31080 Pamplona, Spain
Psychopharmacology (Berl) 224:313-25. 2012..However, most CSDS studies rely only on the analysis of stress-induced social avoidance. Moreover, the predictive validity of the model has been poorly analyzed, let alone its interaction with biological risk factors...
