Estefania Toledo


Affiliation: University of Navarra
Country: Spain


  1. Bibiloni M, Julibert A, Bouzas C, Martinez Gonzalez M, Corella D, Salas Salvado J, et al. Nut Consumptions as a Marker of Higher Diet Quality in a Mediterranean Population at High Cardiovascular Risk. Nutrients. 2019;11: pubmed publisher
    ..nut consumers had better nutrient adequacy, diet quality, and adherence to the MedDiet than those non-nut consumers. ..
  2. Rodríguez García C, Sánchez Quesada C, Toledo E, Delgado Rodriguez M, Gaforio J. Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion?. Molecules. 2019;24: pubmed publisher
    ..Thus, dietary intake of lignan-rich foods could be a useful way to bolster the prevention of chronic illness, such as certain types of cancers and cardiovascular disease. ..
  3. Garcia Arellano A, Martinez Gonzalez M, Ramallal R, Salas Salvado J, Hebert J, Corella D, et al. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies. Clin Nutr. 2018;: pubmed publisher
    ..The SUN cohort and PREDIMED trial were registered at as NCT02669602 and at as ISRCTN35739639, respectively. ..
  4. Sanchez Villegas A, Álvarez Pérez J, Toledo E, Salas Salvado J, Ortega Azorín C, Zomeño M, et al. Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial. Nutrients. 2018;10: pubmed publisher
    ..5⁻1 g/day) was significantly associated with a lower prevalence of depression. In our study, moderate fish and LC ω-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship. ..
  5. Cano Ibáñez N, Bueno Cavanillas A, Martinez Gonzalez M, Corella D, Salas Salvado J, Zomeño M, et al. Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study. Nutrients. 2018;10: pubmed publisher
    ..001). Sex (women), non-smoker and physical activity were also associated to adequate nutrient intake. Geographical area influences nutrient intakes. Its effect on dietary quality should be taken into account when planning food policies. ..
  6. Romanos Nanclares A, Toledo E, Gardeazabal I, Jiménez Moleón J, Martinez Gonzalez M, Gea A. Sugar-sweetened beverage consumption and incidence of breast cancer: the Seguimiento Universidad de Navarra (SUN) Project. Eur J Nutr. 2018;: pubmed publisher
    ..Nonetheless further larger longitudinal studies are needed to support this association. ..
  7. Navarro A, Abasheva D, Martinez Gonzalez M, Ruiz Estigarribia L, Martín Calvo N, Sanchez Villegas A, et al. Coffee Consumption and the Risk of Depression in a Middle-Aged Cohort: The SUN Project. Nutrients. 2018;10: pubmed publisher
    ..37 (95% CI 0.15⁻0.95)). However, overall, we did not observe an inverse linear dose⁻response association between coffee consumption and the incidence of depression (p for trend = 0.22). ..
  8. Lopez del Burgo C, Gea A, de Irala J, Martínez González M, Chavarro J, Toledo E. Alcohol and Difficulty Conceiving in the SUN Cohort: A Nested Case-Control Study. Nutrients. 2015;7:6167-78 pubmed publisher
    ..More studies are needed to clearly elucidate the effects of alcohol intake on women's fertility. In the meantime, recommendations about alcohol intake to couples trying to conceive have to be given cautiously. ..
  9. Muñoz García M, Cervantes S, Razquin C, Guillen Grima F, Toledo J, Martinez Gonzalez M, et al. Validation study of a Spanish version of the modified Telephone Interview for Cognitive Status (STICS-m). Gac Sanit. 2018;: pubmed publisher
    ..Even so, the STICS-m can be regarded as an useful tool in the epidemiological setting since increasing scores appear to be able to predict a lower risk of developing dementia. ..

More Information


  1. Navarro A, Martinez Gonzalez M, Gea A, Ramallal R, Ruiz Canela M, Toledo E. Coffee consumption and risk of hypertension in the SUN Project. Clin Nutr. 2019;38:389-397 pubmed publisher
    ..0452). In the SUN project we found an inverse association between regular coffee consumption and the risk of hypertension in women, which was strongest among women with a suboptimal food pattern (low adherence to the Mediterranean diet). ..
  2. Fito M, Melander O, Martinez J, Toledo E, Carpene C, Corella D. Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention. Int J Mol Sci. 2016;17: pubmed publisher
    ..Nevertheless, these preliminary results can help to better understand the inter-individual differences in cardiovascular risk and dietary response for further applications in personalized nutrition. ..
  3. Díez Espino J, Basterra Gortari F, Salas Salvadó J, Buil Cosiales P, Corella D, Schröder H, et al. Egg consumption and cardiovascular disease according to diabetic status: The PREDIMED study. Clin Nutr. 2017;36:1015-1021 pubmed publisher
    ..55) in diabetics. Low to moderated egg consumption was not associated with an increased CVD risk in diabetic or non-diabetic individuals at high cardiovascular risk. This trial was registered at as ISRCTN35739639. ..
  4. Eguaras S, Toledo E, Hernández Hernández A, Cervantes S, Martínez González M. Better Adherence to the Mediterranean Diet Could Mitigate the Adverse Consequences of Obesity on Cardiovascular Disease: The SUN Prospective Cohort. Nutrients. 2015;7:9154-62 pubmed publisher
    ..Better adherence to the MedDiet was associated with reduced CVD events (p for trend = 0.029). Our results suggest that the MedDiet could mitigate the harmful cardiovascular effect of overweight/obesity. ..
  5. Hernandez Hernandez A, Gea A, Ruiz Canela M, Toledo E, Beunza J, Bes Rastrollo M, et al. Mediterranean Alcohol-Drinking Pattern and the Incidence of Cardiovascular Disease and Cardiovascular Mortality: The SUN Project. Nutrients. 2015;7:9116-26 pubmed publisher
    ..Better conformity with the MADP seemed to be associated with lower cardiovascular risk in most point estimates; however, no significant results were found and more powered studies are needed to clarify the role of the MADP on CVD. ..
  6. Sánchez Villegas A, Henríquez Sánchez P, Ruiz Canela M, Lahortiga F, Molero P, Toledo E, et al. A longitudinal analysis of diet quality scores and the risk of incident depression in the SUN Project. BMC Med. 2015;13:197 pubmed publisher
  7. García Layana A, Ciufo G, Toledo E, Martínez González M, Corella D, Fitó M, et al. The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery. Nutrients. 2017;9: pubmed publisher
    ..Further studies are necessary to investigate whether a MedDiet could have a preventive role in cataract surgery. ..
  8. Buil Cosiales P, Martinez Gonzalez M, Ruiz Canela M, Diez Espino J, Garcia Arellano A, Toledo E. Consumption of Fruit or Fiber-Fruit Decreases the Risk of Cardiovascular Disease in a Mediterranean Young Cohort. Nutrients. 2017;9: pubmed publisher
    ..52, 95% CI 0.30-0.89). In conclusion, high fruit consumption, whole grain consumption, or consumption of at least one serving/week of cruciferous vegetables may be protective against CVD in young Mediterranean populations. ..