Jan Tesarik

Summary

Affiliation: University of Granada
Country: Spain

Publications

  1. ncbi request reprint Apoptosis and necrosis in human ejaculated spermatozoa
    Christian Lachaud
    Department of Biochemistry and Molecular Biology, University of Granada, Campus Universitario Fuentenueva, 18701 Granada, Spain
    Hum Reprod 19:607-10. 2004
  2. ncbi request reprint A zygote is not an embryo: ethical and legal considerations
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 9:13-6. 2004
  3. ncbi request reprint Treatment of severe male infertility by micromanipulation-assisted fertilization: an update
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Granada, Spain
    Front Biosci 12:105-14. 2007
  4. ncbi request reprint Paternal effects acting during the first cell cycle of human preimplantation development after ICSI
    Jan Tesarik
    Laboratoire d Eylau, 55 rue Saint Didier, 75116 Paris, France
    Hum Reprod 17:184-9. 2002
  5. ncbi request reprint Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment
    Ermanno Greco
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    J Androl 26:349-53. 2005
  6. ncbi request reprint Paternal effects on cell division in the human preimplantation embryo
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain, Laboratoire d Eylau, 55 rue Saint Didier, 75116 Paris, France
    Reprod Biomed Online 10:370-5. 2005
  7. ncbi request reprint Caspase-dependent and -independent DNA fragmentation in Sertoli and germ cells from men with primary testicular failure: relationship with histological diagnosis
    Jan Tesarik
    Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:254-61. 2004
  8. ncbi request reprint Associate editor's comment on 'Rescue ICSI of oocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF' by Chen and Kattera. Rescue ICSI revisited
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 18:2122-3. 2003
  9. ncbi request reprint Luteinizing hormone affects uterine receptivity independently of ovarian function
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 7:59-64. 2003
  10. ncbi request reprint Using the male gamete for assisted reproduction: past, present, and future
    Jan Tesarik
    Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    J Androl 24:317-28. 2003

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Apoptosis and necrosis in human ejaculated spermatozoa
    Christian Lachaud
    Department of Biochemistry and Molecular Biology, University of Granada, Campus Universitario Fuentenueva, 18701 Granada, Spain
    Hum Reprod 19:607-10. 2004
    ..Features of both apoptosis and necrosis have been reported in ejaculated human spermatozoa. This study examines the relative contribution of these two modes of cell death to the demise of these terminally differentiated cells...
  2. ncbi request reprint A zygote is not an embryo: ethical and legal considerations
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 9:13-6. 2004
    ....
  3. ncbi request reprint Treatment of severe male infertility by micromanipulation-assisted fertilization: an update
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Granada, Spain
    Front Biosci 12:105-14. 2007
    ..Nevertheless, caution is necessary, particularly concerning the eventual increase in genomic-imprinting abnormalities...
  4. ncbi request reprint Paternal effects acting during the first cell cycle of human preimplantation development after ICSI
    Jan Tesarik
    Laboratoire d Eylau, 55 rue Saint Didier, 75116 Paris, France
    Hum Reprod 17:184-9. 2002
    ..This study was undertaken to determine whether paternal influences on human embryo quality are detectable as early as the first cell cycle after fertilization...
  5. ncbi request reprint Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment
    Ermanno Greco
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    J Androl 26:349-53. 2005
    ..These data show that sperm DNA damage can be efficiently treated with oral antioxidants administered during a relatively short time period...
  6. ncbi request reprint Paternal effects on cell division in the human preimplantation embryo
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain, Laboratoire d Eylau, 55 rue Saint Didier, 75116 Paris, France
    Reprod Biomed Online 10:370-5. 2005
    ..ICSI with testicular spermatozoa has recently been shown to be an efficient treatment for the late paternal effect. The use of oral antioxidant treatment in this indication has also given promising results...
  7. ncbi request reprint Caspase-dependent and -independent DNA fragmentation in Sertoli and germ cells from men with primary testicular failure: relationship with histological diagnosis
    Jan Tesarik
    Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:254-61. 2004
    ..This study examines the participation of typical (caspase-dependent) and atypical (caspase-independent) pathways in these processes...
  8. ncbi request reprint Associate editor's comment on 'Rescue ICSI of oocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF' by Chen and Kattera. Rescue ICSI revisited
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 18:2122-3. 2003
  9. ncbi request reprint Luteinizing hormone affects uterine receptivity independently of ovarian function
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 7:59-64. 2003
    ..It is concluded that endometrial maturation is disturbed in women with low endogenous LH but can be rescued by mid-cycle stimulation of LH receptor with exogenous HCG in the absence of ovarian activity...
  10. ncbi request reprint Using the male gamete for assisted reproduction: past, present, and future
    Jan Tesarik
    Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    J Androl 24:317-28. 2003
  11. ncbi request reprint Microfilament disruption is required for enucleation and nuclear transfer in germinal vesicle but not metaphase II human oocytes
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Granada, Spain
    Fertil Steril 79:677-81. 2003
    ..To evaluate the usefulness of microfilament disruption before enucleation and nuclear transfer in human oocytes at different stages of maturation...
  12. ncbi request reprint Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:611-5. 2004
    ..It is known that repeated failure of assisted reproduction treatment (ART) can be due to a paternal effect. This study was undertaken to analyse the possible relationship between ART failure and sperm DNA fragmentation...
  13. ncbi request reprint ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment
    Ermanno Greco
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    Hum Reprod 20:2590-4. 2005
    ..ICSI with testicular sperm samples has recently been suggested for these cases. Here we test a less invasive approach based on oral antioxidant treatment prior to ICSI with ejaculated spermatozoa...
  14. ncbi request reprint Developmental potential of fully intact and partially damaged cryopreserved embryos after laser-assisted removal of necrotic blastomeres and post-thaw culture selection
    Laura Rienzi
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    Fertil Steril 84:888-94. 2005
    ..This study was undertaken to compare the performance of intact frozen and thawed embryos with that of partially damaged embryos after removal of the necrotic blastomeres...
  15. ncbi request reprint In-vitro effects of FSH and testosterone withdrawal on caspase activation and DNA fragmentation in different cell types of human seminiferous epithelium
    Jan Tesarik
    Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 17:1811-9. 2002
    ..However, caspase activity in different cell types of this epithelium has never been addressed...
  16. ncbi request reprint Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa
    Ermanno Greco
    Centre for Reproductive Medicine, European Hospital, Via Portuense 700, 00149 Rome, Italy
    Hum Reprod 20:226-30. 2005
    ..Previous findings have suggested that clinically relevant sperm DNA damage may occur at the post-testicular level. This study was undertaken to assess the clinical usefulness of ICSI with testicular spermatozoa in this indication...
  17. ncbi request reprint Day 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer
    Laura Rienzi
    Reproductive Medicine, European Hospital, Via Portuense 700, 00149 Rome, Italy
    Hum Reprod 17:1852-5. 2002
    ..The respective advantages of day 3 and day 5 embryo transfer are a matter of debate. Previous comparisons did not include pronuclear stage zygote scoring and cumulative success rates (fresh and cryopreserved embryos)...
  18. ncbi request reprint Beneficial effect of luteal-phase GnRH agonist administration on embryo implantation after ICSI in both GnRH agonist- and antagonist-treated ovarian stimulation cycles
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Granada, Spain
    Hum Reprod 21:2572-9. 2006
    ..This prospective randomized study evaluates the effect of GnRH agonist administered in the luteal phase on ICSI outcomes in both GnRH agonist- and GnRH antagonist-treated ovarian stimulation protocols...
  19. ncbi request reprint Effects of exogenous LH administration during ovarian stimulation of pituitary down-regulated young oocyte donors on oocyte yield and developmental competence
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada
    Hum Reprod 17:3129-37. 2002
    ..The role of exogenous LH supplementation in ovarian stimulation is a matter of debate. Here we evaluate the impact of exogenous LH on oocyte yield and developmental competence in an oocyte donation programme...
  20. ncbi request reprint Caspase activity in preimplantation human embryos is not associated with apoptosis
    Francisco Martinez
    University of Granada, Campus Universitario Fuentenueva, Granada, Spain
    Hum Reprod 17:1584-90. 2002
    ..However, some reports on human embryos questioned the causal relationship between blastomere fragmentation and apoptosis, and information about the presence and activity of caspases in human embryos is lacking...
  21. ncbi request reprint Birth of a healthy boy after fertilization of cryopreserved oocytes with cryopreserved testicular spermatozoa from a man with nonmosaic Klinefelter syndrome
    Ermanno Greco
    Center for Reproductive Medicine, European Hospital, Rome, Italy
    Fertil Steril 89:991.e5-7. 2008
    ..To report the first birth with frozen spermatozoa and frozen oocytes in a case of nonmosaic Klinefelter syndrome...
  22. pmc Blastomere cytoplasmic granularity is unrelated to developmental potential of day 3 human embryos
    Laura Rienzi
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    J Assist Reprod Genet 20:314-7. 2003
    ..To examine whether the increase in cytoplasmic granularity observed in some human embryos on day 3 of development is of any predictive value as to embryo developmental potential...
  23. ncbi request reprint Use of a modified intracytoplasmic sperm injection technique to overcome sperm-borne and oocyte-borne oocyte activation failures
    Jan Tesarik
    MAR and Gen Molecular Assisted Reproduction and Genetics, Granada, Spain
    Fertil Steril 78:619-24. 2002
    ..To examine whether sperm-borne and oocyte-borne oocyte activation failures can be overcome by mechanical means that entail modifying the ICSI technique...
  24. doi request reprint Sperm vacuoles negatively affect outcomes in intracytoplasmic morphologically selected sperm injection in terms of pregnancy, implantation, and live-birth rates
    Ermanno Greco
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    Fertil Steril 100:379-85. 2013
    ..To retrospectively evaluate whether sperm vacuoles influence clinical results, with a particular focus on live-birth rates, in 101 intracytoplasmic morphologically selected sperm injection (IMSI) cycles...
  25. ncbi request reprint Limiting the number of injected oocytes to three impairs ICSI outcomes in patients with nonobstructive azoospermia
    E Greco
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    Hum Reprod 21:1521-4. 2006
    ..A previous study failed to show an impact of this restriction on fresh embryo transfer outcomes. The objective of this study was to compare ICSI outcomes before and after this restriction in patients with nonobstructive azoospermia...
  26. ncbi request reprint Laser-assisted removal of necrotic blastomeres from cryopreserved embryos that were partially damaged
    Laura Rienzi
    Centre for Reproductive Medicine, European Hospital, Rome, Italy
    Fertil Steril 77:1196-201. 2002
    ..To examine whether the developmental potential of embryos that were partially damaged after freezing and thawing can be improved by removal of necrotic blastomeres before embryo transfer...
  27. ncbi request reprint Improvement of delivery and live birth rates after ICSI in women aged >40 years by ovarian co-stimulation with growth hormone
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Granada, Spain
    Hum Reprod 20:2536-41. 2005
    ..This prospective randomized study evaluates the usefulness of GH administration in women of >40 years undergoing ovarian stimulation for assisted reproduction treatment...
  28. ncbi request reprint Follicular fluid markers of oocyte developmental potential
    Carmen Mendoza
    Department of Biochemistry and Molecular Biology, University of Granada, Granada, Spain
    Hum Reprod 17:1017-22. 2002
    ..Concentrations of certain substances in follicular fluid (FF) are related to fertilization outcome and early post-fertilization development. The study aim was to identify FF markers with which to predict embryo implantation potential...
  29. ncbi request reprint Enhancement of embryo developmental potential by a single administration of GnRH agonist at the time of implantation
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:1176-80. 2004
    ..Moreover, some studies suggested that, unexpectedly, the embryo developmental potential is improved in these conditions. This prospective controlled study was designed to test this hypothesis...
  30. ncbi request reprint Pharmacological concentrations of follicle-stimulating hormone and testosterone improve the efficacy of in vitro germ cell differentiation in men with maturation arrest
    Jan Tesarik
    Laboratoire d Eylau, Paris, France
    Fertil Steril 77:245-51. 2002
    ..To examine whether in vitro differentiation of germ cells from men with maturation arrest is improved by augmenting FSH and T concentrations above the values effective in samples from men with normal spermatogenesis...
  31. ncbi request reprint Sperm nuclear DNA damage: update on the mechanism, diagnosis and treatment
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 12:715-21. 2006
    ..A rational approach to the interpretation of sperm DNA fragmentation data and to the choice of the optimal treatment method is suggested...
  32. ncbi request reprint Somatic cell haploidization: an update
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Reprod Biomed Online 6:60-5. 2003
    ..Experiments are currently under way to assess the regularity of chromatid segregation during somatic nucleus haploidization...
  33. ncbi request reprint Comparative genomic hybridization selection of blastocysts for repeated implantation failure treatment: a pilot study
    Ermanno Greco
    Center for Reproductive Medicine, European Hospital, Via Portuense 700, 00149 Rome, Italy
    Biomed Res Int 2014:457913. 2014
    ..2%) patients of group RIF NO PGS. In conclusion, PGS by array CGH with single euploid blastocyst transfer appears to be a successful strategy for patients with multiple failed IVF attempts. ..