Fabian Sanchis-Gomar

Summary

Affiliation: University of Valencia
Country: Spain

Publications

  1. doi request reprint Telmisartan as metabolic modulator: a new perspective in sports doping?
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Research Foundation of the University Clinic Hospital of Valencia INCLIVA, Valencia, Spain
    J Strength Cond Res 26:608-10. 2012
  2. doi request reprint A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging
    Fabian Sanchis-Gomar
    Research Institute of Hospital 12 de Octubre i 12, Avda de Cordoba s n, 28041, Madrid, Spain
    Age (Dordr) 37:9776. 2015
  3. doi request reprint Acute myocardial infarction: 'telomerasing' for cardioprotection
    Fabian Sanchis-Gomar
    Research Institute, Hospital 12 de Octubre i 12, Avda de Cordoba s n, 28041 Madrid, Spain Electronic address
    Trends Mol Med 21:203-5. 2015
  4. pmc FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs
    Fabian Sanchis-Gomar
    Department of Physiology, University of Valencia and Fundación para la Investigación del Hospital Clínico Universitario INCLIVA, Av Blasco Ibanez, 15, Valencia, 46010, Spain
    Age (Dordr) 36:9733. 2014
  5. pmc Effects of allopurinol on exercise-induced muscle damage: new therapeutic approaches?
    F Sanchis-Gomar
    Department of Physiology, University of Valencia, Av Blasco Ibanez, 15, Valencia, 46010, Spain
    Cell Stress Chaperones 20:3-13. 2015
  6. doi request reprint Erythropoietin and the heart: physiological effects and the therapeutic perspective
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain Fundación Investigación Hospital Clínico Universitario INCLIVA, Spain Electronic address
    Int J Cardiol 171:116-25. 2014
  7. doi request reprint Effects of acute exercise and xanthine oxidase inhibition on novel cardiovascular biomarkers
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Spain
    Transl Res 162:102-9. 2013
  8. doi request reprint Hemoglobin point-of-care testing: the HemoCue system
    Fabian Sanchis-Gomar
    University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    J Lab Autom 18:198-205. 2013
  9. pmc Erythropoietin receptor (EpoR) agonism is used to treat a wide range of disease
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Research Foundation of the University Clinic Hospital of Valencia INCLIVA, Valencia, Spain
    Mol Med 19:62-4. 2013
  10. doi request reprint Sestrins: novel antioxidant and AMPK-modulating functions regulated by exercise?
    Fabian Sanchis-Gomar
    Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    J Cell Physiol 228:1647-50. 2013

Collaborators

Detail Information

Publications37

  1. doi request reprint Telmisartan as metabolic modulator: a new perspective in sports doping?
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Research Foundation of the University Clinic Hospital of Valencia INCLIVA, Valencia, Spain
    J Strength Cond Res 26:608-10. 2012
    ..The 2012 WADA prohibited list does not provide telmisartan for a potential doping drug, but arguments supporting the consideration to include them among "metabolic modulators" are at hand...
  2. doi request reprint A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging
    Fabian Sanchis-Gomar
    Research Institute of Hospital 12 de Octubre i 12, Avda de Cordoba s n, 28041, Madrid, Spain
    Age (Dordr) 37:9776. 2015
    ..Whether the four-biomarker panel may predict successful aging deserves further scrutiny. ..
  3. doi request reprint Acute myocardial infarction: 'telomerasing' for cardioprotection
    Fabian Sanchis-Gomar
    Research Institute, Hospital 12 de Octubre i 12, Avda de Cordoba s n, 28041 Madrid, Spain Electronic address
    Trends Mol Med 21:203-5. 2015
    ..Given that regular physical exercise also activates this gene, therapeutic and lifestyle interventions targeting telomerase need to be explored as possible additions to the current armamentarium for myocardial regeneration. ..
  4. pmc FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs
    Fabian Sanchis-Gomar
    Department of Physiology, University of Valencia and Fundación para la Investigación del Hospital Clínico Universitario INCLIVA, Av Blasco Ibanez, 15, Valencia, 46010, Spain
    Age (Dordr) 36:9733. 2014
    ..Further research is needed with different cohorts as well as with additional variants in the FNDC5 gene or in other genes involved in irisin signaling. ..
  5. pmc Effects of allopurinol on exercise-induced muscle damage: new therapeutic approaches?
    F Sanchis-Gomar
    Department of Physiology, University of Valencia, Av Blasco Ibanez, 15, Valencia, 46010, Spain
    Cell Stress Chaperones 20:3-13. 2015
    ....
  6. doi request reprint Erythropoietin and the heart: physiological effects and the therapeutic perspective
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain Fundación Investigación Hospital Clínico Universitario INCLIVA, Spain Electronic address
    Int J Cardiol 171:116-25. 2014
    ..An overview of non-haematopoietic Epo analogues, which are a reliable alternative to the classic EpoR agonists and may prevent undesired side effects, is also provided. ..
  7. doi request reprint Effects of acute exercise and xanthine oxidase inhibition on novel cardiovascular biomarkers
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Spain
    Transl Res 162:102-9. 2013
    ....
  8. doi request reprint Hemoglobin point-of-care testing: the HemoCue system
    Fabian Sanchis-Gomar
    University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    J Lab Autom 18:198-205. 2013
    ....
  9. pmc Erythropoietin receptor (EpoR) agonism is used to treat a wide range of disease
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Research Foundation of the University Clinic Hospital of Valencia INCLIVA, Valencia, Spain
    Mol Med 19:62-4. 2013
    ....
  10. doi request reprint Sestrins: novel antioxidant and AMPK-modulating functions regulated by exercise?
    Fabian Sanchis-Gomar
    Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    J Cell Physiol 228:1647-50. 2013
    ..To date, the SESNs-exercise relationship has not been explored. However, this emerging family of stress proteins may be part of the redox-based adaptive response to exercise...
  11. ncbi request reprint Effects of acute exercise and allopurinol administration on soluble urokinase plasminogen activator receptor (suPAR)
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    Clin Lab 59:207-10. 2013
    ....
  12. doi request reprint Physical exercise as an epigenetic modulator: Eustress, the "positive stress" as an effector of gene expression
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Valencia, Spain
    J Strength Cond Res 26:3469-72. 2012
    ..We propose herein that stress may stimulate genetic adaptations through epigenetics that, in turn, modulate the link between the environment, human lifestyle factors, and genes...
  13. doi request reprint Intermittent hypobaric hypoxia applicability in myocardial infarction prevention and recovery
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain
    J Cell Mol Med 16:1150-4. 2012
    ..As such, further research is needed before IHH can be widely advocated in myocardial infarction prevention and recovery...
  14. doi request reprint The loss of muscle mass and sarcopenia: non hormonal intervention
    Fabian Sanchis-Gomar
    Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Spain
    Exp Gerontol 46:967-9. 2011
    ..Moreover, any significant improvement in the loss of muscle function will be a major breakthrough in the health and welfare of the population...
  15. pmc Vitamin C supplementation does not improve hypoxia-induced erythropoiesis
    Vladimir E Martinez-Bello
    Faculty of Medicine, Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    High Alt Med Biol 13:269-74. 2012
    ..However, we found an increase in plasma protein oxidation in both hypoxic groups. Vitamin C does not affect erythropoiesis and protein oxidation in rats submitted to intermittent hypoxic exposure...
  16. doi request reprint Three weeks of erythropoietin treatment hampers skeletal muscle mitochondrial biogenesis in rats
    Vladimir E Martinez-Bello
    Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    J Physiol Biochem 68:593-601. 2012
    ..Our findings suggest that 3 weeks of rHuEpo treatment, which generates an increase of oxygen carrying capacity, can affect mitochondrial biogenesis in a muscle fibre-specific dependent manner...
  17. doi request reprint Elite athletes live longer than the general population: a meta-analysis
    Nuria Garatachea
    Department of Physiotherapy and Nursing, University of Zaragoza, Huesca, Spain Research Institute of Hospital 12 de Octubre i 12, Madrid, Spain
    Mayo Clin Proc 89:1195-200. 2014
    ..To perform a meta-analysis of cohort studies aimed at providing an accurate overview of mortality in elite athletes...
  18. pmc Physical inactivity and low fitness deserve more attention to alter cancer risk and prognosis
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain Fundación Investigación Hospital Clínico Universitario INCLIVA Spain
    Cancer Prev Res (Phila) 8:105-10. 2015
    ....
  19. ncbi request reprint Pharmacological properties of physical exercise in the elderly
    Jose Vina
    Department of Physiology Faculty of Medicine University of Valencia, Av Blasco Ibanez, 15, Valencia, E46010 Spain
    Curr Pharm Des 20:3019-29. 2014
    ..If old adults adopted a more active lifestyle, there would be a significant delay in frailty and dependency with clear benefits to individual well-being and to the public's health. ..
  20. doi request reprint Methodological considerations to determine the effect of exercise on brain-derived neurotrophic factor levels
    Helios Pareja-Galeano
    Department of Physiology, School of Medicine, University of Valencia, INCLIVA, Valencia, Spain Electronic address
    Clin Biochem 48:162-6. 2015
    ..However, there is yet no consensus about the adequate blood processing conditions to standardize its assessment. We aimed to find a reliable blood sample processing method to determine changes in BDNF due to exercise...
  21. doi request reprint Mitochondria as sources and targets of damage in cellular aging
    Mari Carmen Gomez-Cabrera
    Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    Clin Chem Lab Med 50:1287-95. 2012
    ..The promotion of mitochondriogenesis is critical to prevent aging. In skeletal muscle it has relevance to prevent sarcopenia and frailty...
  22. doi request reprint Inhibition of xanthine oxidase to prevent statin-induced myalgia and rhabdomiolysis
    Rafael Alis
    Research Institute Dr Viña Giner, Molecular and Mitochondrial Medicine, Catholic University of Valencia San Vicente Mártir, Valencia, Spain School of Medicine, Catholic University of Valencia San Vicente Mártir, Valencia, Spain
    Atherosclerosis 239:38-42. 2015
    ....
  23. doi request reprint Influence of training and a maximal exercise test in analytical variability of muscular, hepatic, and cardiovascular biochemical variables
    Marco Romagnoli
    Universitary Research Institute Dr Viña Giner, Molecular and Mitochondrial Medicine, Catholic University of Valencia San Vicente Mártir, Valencia, Spain
    Scand J Clin Lab Invest 74:192-8. 2014
    ..A single maximal exercise was also effective to transiently increase the concentrations of NT-proBNP, but not those of Hs-TnT, thus suggesting that the cardiac involvement is mostly benign in nature...
  24. doi request reprint Living at high altitude in combination with sea-level sprint training increases hematological parameters but does not improve performance in rats
    Vladimir Essau Martinez-Bello
    Department of Physiology, Faculty of Medicine, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Blasco Ibañez, 15, 46010 Valencia, Spain
    Eur J Appl Physiol 111:1147-56. 2011
    ..However, contrary to our starting hypothesis, the combination of normobaric hypoxia and sprint training did not improve MAV in our animals...
  25. doi request reprint Mitochondrial biogenesis in exercise and in ageing
    Jose Vina
    Department of Physiology, University of Valencia, Spain
    Adv Drug Deliv Rev 61:1369-74. 2009
    ..In this chapter we consider the interrelationship between mitochondrial biogenesis stimulated by exercise and the possible impairment of this pathway in ageing leading to mitochondrial deficiency and eventually muscle sarcopenia...
  26. pmc Physical activity - an important preanalytical variable
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia Fundación Investigación Hospital Clínico Universitario INCLIVA, Valencia, Spain
    Biochem Med (Zagreb) 24:68-79. 2014
    ....
  27. doi request reprint Current limitations of the Athlete's Biological Passport use in sports
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Spain
    Clin Chem Lab Med 49:1413-5. 2011
    ....
  28. doi request reprint Altitude exposure in sports: the Athlete Biological Passport standpoint
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Spain Fundación Investigación Hospital Clínico Universitario INCLIVA, Spain
    Drug Test Anal 6:190-3. 2014
    ..In particular, modifications of haematological parameters during and after exposure to different altitudes/hypoxic protocols need to be properly included within detection models...
  29. doi request reprint Association between irisin and homocysteine in euglycemic and diabetic subjects
    Rafael Alis
    Research University Institute Dr Viña Giner, Molecular and Mitochondrial Medicine, Catholic University of Valencia San Vicente Mártir, Valencia, Spain Faculty of Medicine, Catholic University of Valencia San Vicente Mártir, Valencia, Spain
    Clin Biochem 47:333-5. 2014
    ..The aim of study was to explore whether a relationship exists between homocysteine and irisin in type 2 diabetes (T2D) patients-a population with a high risk of developing cardiovascular disease-and euglycemic controls...
  30. ncbi request reprint Mitochondrial biogenesis in health and disease. Molecular and therapeutic approaches
    Fabian Sanchis-Gomar
    Department of Physiology Faculty of Medicine and Dentistry, University of Valencia, Av Blasco Ibanez, 15, Valencia, E46010 Spain
    Curr Pharm Des 20:5619-33. 2014
    ..Furthermore, evidence based results and the knowledge gained during last years for some of these drugs aim us hypothesize about the value of a given treatment involved in the activation of MB. ..
  31. doi request reprint Blood rheology effect of submaximal exercise on young subjects
    Marco Romagnoli
    School of Medicine, Catholic University of Valencia, Valencia, Spain
    Clin Hemorheol Microcirc 56:111-7. 2014
    ..001). Plasma volume slightly reduced which may explain the lack of changes in blood viscosity. The results of the present study indicate a similar hemorheological response to submaximal exercise in both young people and adults. ..
  32. doi request reprint [Effects of physical exercise on cognitive alterations and oxidative stress in an APP/PSN1 transgenic model of Alzheimer's disease]
    Helios Pareja-Galeano
    Departamento de Fisiologia, Facultad de Medicina, Universidad de Valencia, Valencia, Spain
    Rev Esp Geriatr Gerontol 47:198-204. 2012
    ..This model is mainly based on the cerebral deposition of amyloid β plaques...
  33. doi request reprint p16INK4a, NAD(+) , and sestrins: new targets for combating aging-related chronic illness?
    Helios Pareja-Galeano
    Department of Physiology, Faculty of Medicine, Universidad de Valencia, Valencia, Spain Fundación Investigación Hospital Clínico Universitario INCLIVA, Valencia, Spain
    J Cell Physiol 229:1575-6. 2014
    ..New possible targets have been recently discovered, are clearly involved in age-related pathologies and might benefit the treatment of other age-related conditions, particularly metabolic diseases...
  34. doi request reprint PPARgamma agonist pioglitazone does not enhance performance in mice
    Fabian Sanchis-Gomar
    Department of Physiology, Faculty of Medicine, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Spain
    Drug Test Anal 6:922-9. 2014
    ..No effect of treatment was found. Therefore in our study, pioglitazone administration did not affect mitochondrial biogenesis signaling pathway...
  35. doi request reprint Physical exercise and epigenetic modulation: elucidating intricate mechanisms
    Helios Pareja-Galeano
    Department of Physiology, Faculty of Medicine, University of Valencia, Av Blasco Ibanez, 15, Valencia, 46010, Spain
    Sports Med 44:429-36. 2014
    ..In this article, we describe several of these substrates and signaling molecules regulated by exercise that affect some of the most important epigenetic mechanisms, which, in turn, control the gene expression involved in metabolism. ..
  36. doi request reprint Irisinemia: a novel concept to coin in clinical medicine?
    Fabian Sanchis-Gomar
    Faculty of Medicine, Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario INCLIVA, Valencia, Spain
    Ann Nutr Metab 63:60-1. 2013
    ....
  37. doi request reprint Could thiazolidinediones increase the risk of heart failure in Friedreich's ataxia patients?
    José L García-Giménez
    CIBERER, Biomedical Network Research Centre on Rare Diseases, Valencia, Spain
    Mov Disord 26:769-71. 2011
    ..In our opinion, the possible fatal consequences must be taken into account when peroxisome proliferator-activated receptor-gamma agonist drugs are considered as possible therapeutic agents for Friedreich's ataxia patients...