Javier Salmeron

Summary

Affiliation: University of Granada
Country: Spain

Publications

  1. ncbi request reprint Quasispecies as predictive response factors for antiviral treatment in patients with chronic hepatitis C
    Javier Salmeron
    Gastroenterology Unit, Hospital Universitario San Cecilio, Granada, Spain
    Dig Dis Sci 51:960-7. 2006
  2. doi request reprint Quasispecies as predictive factor of rapid, early and sustained virological responses in chronic hepatitis C, genotype 1, treated with peginterferon-ribavirin
    Javier Salmeron
    Gastroenterology Unit, San Cecilio University Hospital and Ciberehd, Granada, Spain
    J Clin Virol 41:264-9. 2008
  3. doi request reprint Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin
    Paloma Muñoz De Rueda
    Unidad de Aparato Digestivo, Hospital Universitario San Cecilio, Granada, Spain
    Am J Gastroenterol 106:1246-54. 2011
  4. pmc Variation of transaminases, HCV-RNA levels and Th1/Th2 cytokine production during the post-partum period in pregnant women with chronic hepatitis C
    Angeles Ruiz-Extremera
    Paediatric Unit, San Cecilio University Hospital, Granada, Spain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, CIBERehd, Granada, Spain Paediatric Unit, Granada University, Granada, Spain
    PLoS ONE 8:e75613. 2013
  5. doi request reprint Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children
    Angeles Ruiz-Extremera
    San Cecilio University Hospital, Granada, Spain
    Hepatology 53:1830-8. 2011
  6. doi request reprint Importance of IL-10 and IL-6 during chronic hepatitis C genotype-1 treatment and their relation with IL28B
    Esther J Pavón-Castillero
    Unidad de Gestión Clínica de Aparato Digestivo, Hospital Universitario San Cecilio, Granada, Spain
    Cytokine 61:595-601. 2013
  7. doi request reprint Factors associated with hepatic steatosis in obese children and adolescents
    Angeles Ruiz-Extremera
    Paedriatric Unit, San Cecilio University Hospital, Granada, Spain
    J Pediatr Gastroenterol Nutr 53:196-201. 2011
  8. doi request reprint Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles
    Jose A Muñoz-Gámez
    Clinical Management Unit of Digestive Disease and UNAI, San Cecilio University Hospital, Granada, Spain
    Liver Int 35:1430-41. 2015
  9. doi request reprint Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer
    Josefa Leon
    San Cecilio University Hospital, Granada, Spain
    Mol Carcinog 51:608-18. 2012
  10. doi request reprint Hepatic expression of adiponectin receptors increases with non-alcoholic fatty liver disease progression in morbid obesity in correlation with glutathione peroxidase 1
    Angel Carazo
    Research Unit, San Cecilio University Hospital, Av de Madrid s n, 18012, Granada, Spain
    Obes Surg 21:492-500. 2011

Collaborators

  • Luis Rodriguez
  • Manuel Romero-Gomez
  • Angeles Ruiz Extremera
  • David Martin-Oliva
  • Francisco O'Valle
  • Jordi Muntane
  • Ricardo Moreno-Otero
  • Moises Diago
  • Angeles Ruiz-Extremera
  • Josefa Leon
  • Angel Carazo
  • Rosa Quiles-Perez
  • Jorge Casado
  • Ana Gila
  • Paloma Muñoz-De-Rueda
  • Laura Sanjuan-Nuñez
  • Rosa Quiles
  • Paloma Muñoz de Rueda
  • Jose A Muñoz-Gámez
  • Ana Belén Martín
  • José Antonio Muñoz-Gámez
  • Paloma Muñoz De Rueda
  • Esther Ocete-Hita
  • Julián López Viota
  • Esther José Pavón-Castillero
  • Angela Ruiz-Extremera
  • Esther J Pavón-Castillero
  • María Angustias Salmerón-Ruiz
  • Laura Sanjuan
  • Jose Antonio Muñoz
  • Esther José Pavón
  • Trinidad Caballero
  • Angel Delgado
  • Andrés Barrientos
  • Russel J Reiter
  • Isabel Carmona
  • Cristina González-Puga
  • Sergio M Jiménez Ruiz
  • Esther J Pavón
  • Juan D Rejón
  • María Sol Zurita
  • Rosario López-Segura
  • Ana Abril-Molina
  • Sergio Manuel Jimenez-Ruiz
  • Pilar Martinez
  • Sergio Ruiz
  • Paloma de la Cueva
  • Ana Maté
  • Pablo Palomares
  • Angela Salmerón
  • Paloma Sanz-Cameno
  • Ana Martin
  • Luis Miguel Alcázar
  • Pablo Saenz-Lopez
  • Alejandro Goicoechea
  • Esther Ocete
  • José Manuel Fernández
  • Ana Gila-Medina
  • Esther Pavón
  • Antonia Martín-Casares
  • Maximiliano Garofano
  • Sergio Delgado
  • Miguel Angel Lopez-Nevot
  • Raul Gonzalez
  • Ana Belén Martín-Alvarez
  • Francisco Javier Oliver
  • María A López-Garrido
  • María D Quintero
  • Enriqueta Barranco

Detail Information

Publications14

  1. ncbi request reprint Quasispecies as predictive response factors for antiviral treatment in patients with chronic hepatitis C
    Javier Salmeron
    Gastroenterology Unit, Hospital Universitario San Cecilio, Granada, Spain
    Dig Dis Sci 51:960-7. 2006
    ..In conclusion, the predictive factors of virologic response are genotype, viral load, and quasispecies. Quasispecies did not improve on the genotype or the viral load as predictors of virologic response...
  2. doi request reprint Quasispecies as predictive factor of rapid, early and sustained virological responses in chronic hepatitis C, genotype 1, treated with peginterferon-ribavirin
    Javier Salmeron
    Gastroenterology Unit, San Cecilio University Hospital and Ciberehd, Granada, Spain
    J Clin Virol 41:264-9. 2008
    ..The relationship between the complexity of the hypervariable region 1 quasispecies of HCV and responsiveness to therapy is not completely clear...
  3. doi request reprint Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin
    Paloma Muñoz De Rueda
    Unidad de Aparato Digestivo, Hospital Universitario San Cecilio, Granada, Spain
    Am J Gastroenterol 106:1246-54. 2011
    ..This paper investigates the relationships among the host genetic factors HLA and IL28B, viral factors, and the outcome of combination therapy...
  4. pmc Variation of transaminases, HCV-RNA levels and Th1/Th2 cytokine production during the post-partum period in pregnant women with chronic hepatitis C
    Angeles Ruiz-Extremera
    Paediatric Unit, San Cecilio University Hospital, Granada, Spain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, CIBERehd, Granada, Spain Paediatric Unit, Granada University, Granada, Spain
    PLoS ONE 8:e75613. 2013
    ..In the Type-B women, the high partum levels of Th1 cytokines and the absence of post-partum variation in ALT and HCV-RNA levels may be related to permanent Th1 cytokine stimulation. ..
  5. doi request reprint Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children
    Angeles Ruiz-Extremera
    San Cecilio University Hospital, Granada, Spain
    Hepatology 53:1830-8. 2011
    ..The factors influencing viral clearance among the infected children were genotype non-1 and genotype CC of IL28B. In logistic regression, child CC polymorphism was the only predictor of HCV-clearance in HCV genotype-1...
  6. doi request reprint Importance of IL-10 and IL-6 during chronic hepatitis C genotype-1 treatment and their relation with IL28B
    Esther J Pavón-Castillero
    Unidad de Gestión Clínica de Aparato Digestivo, Hospital Universitario San Cecilio, Granada, Spain
    Cytokine 61:595-601. 2013
    ..003 and P ≤ 0.001, respectively). None of the polymorphisms of IL-10 or IL-6 studied were associated with SVR...
  7. doi request reprint Factors associated with hepatic steatosis in obese children and adolescents
    Angeles Ruiz-Extremera
    Paedriatric Unit, San Cecilio University Hospital, Granada, Spain
    J Pediatr Gastroenterol Nutr 53:196-201. 2011
    ..Obesity is associated with high prevalence of hepatic steatosis. We speculate that determinant factors of susceptibility to hepatic steatosis in obesity could differ between children and adolescents...
  8. doi request reprint Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles
    Jose A Muñoz-Gámez
    Clinical Management Unit of Digestive Disease and UNAI, San Cecilio University Hospital, Granada, Spain
    Liver Int 35:1430-41. 2015
    ..The objective of this study was to examine a new strategy for HCC treatment, namely the use of poly (ADP-ribose) polymerase 1 (PARP-1) inhibitor (ABT-888) together with Temozolomide (TMZ) incorporated onto magnetic nanoparticles...
  9. doi request reprint Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer
    Josefa Leon
    San Cecilio University Hospital, Granada, Spain
    Mol Carcinog 51:608-18. 2012
    ..These results could indicate a possible interaction of these pathways...
  10. doi request reprint Hepatic expression of adiponectin receptors increases with non-alcoholic fatty liver disease progression in morbid obesity in correlation with glutathione peroxidase 1
    Angel Carazo
    Research Unit, San Cecilio University Hospital, Av de Madrid s n, 18012, Granada, Spain
    Obes Surg 21:492-500. 2011
    ..We speculate that changes in the hepatic expression levels of the two adiponectin receptors may be associated with the expression of oxidative stress-related genes...
  11. doi request reprint [The value of genetics in the era of hepatitis C triple therapy]
    Rosa Quiles-Perez
    Unidad de Apoyo a la Investigación, Hospital Universitario San Cecilio, Granada, España CIBERehd, Instituto de Salud Carlos III, Madrid, Espana
    Gastroenterol Hepatol 37:427-37. 2014
    ..Study of the polymorphisms of the IFNL3 gene (IL28B), ITPA, IFN-stimulated genes (ISGs), TT/ΔG (ss469415590; IFNL4)) and RBV transporters could help in the decision to prescribe dual or triple therapy in treatment naïve patients...
  12. doi request reprint Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ
    Josefa Leon
    Research Support Unit, San Cecilio University Hospital, Granada, Spain Ciber of Hepatic and Digestive Diseases CIBERehd, Granada, Spain
    J Pineal Res 56:415-26. 2014
    ..In conclusion, melatonin may be useful in treating colon carcinoma in which the activation of ET-1 plays a role in tumour growth and progression. ..
  13. doi request reprint Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
    Rosa Quiles-Perez
    San Cecilio University Hospital, Granada, Spain
    Hepatology 51:255-66. 2010
    ..05)...
  14. ncbi request reprint Activity of hepatic enzymes from week sixteen of pregnancy
    Angeles Ruiz-Extremera
    Pediatrics Service, H Universitario San Cecilio, Granada, Spain
    Am J Obstet Gynecol 193:2010-6. 2005
    ..This study was undertaken to determine the prevalence, epidemiology, and mother-child repercussions of increased alanine-aminotransferase levels from week 16 of pregnancy...