M J Ruiz

Summary

Affiliation: University of Valencia
Country: Spain

Publications

  1. ncbi Genotoxicity of six pesticides by Salmonella mutagenicity test and SOS chromotest
    M J Ruiz
    Laboratori de Toxicologia, Facultat de Formàcia, Universitat de Valencia, Spain
    Mutat Res 390:245-55. 1997
  2. ncbi Toxicological interactions between the mycotoxins beauvericin, deoxynivalenol and T-2 toxin in CHO-K1 cells in vitro
    M J Ruiz
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Toxicon 58:315-26. 2011
  3. ncbi Cytotoxic effects of mycotoxin combinations in mammalian kidney cells
    Maria Jose Ruiz
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Food Chem Toxicol 49:2718-24. 2011
  4. ncbi Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic
    M J Ruiz
    Departamento de Fisiologia, Facultat de Farmacia, Universitat de Valencia, Valencia, Spain
    J Agric Food Chem 57:3180-6. 2009
  5. ncbi Study of the potential toxicity of enniatins A, A(1), B, B(1) by evaluation of duodenal and colonic bioavailability applying an in vitro method by Caco-2 cells
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Valencia, Spain
    Toxicon 59:1-11. 2012
  6. ncbi Co-occurrence and risk assessment of mycotoxins in food and diet from Mediterranean area
    A B Serrano
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem 135:423-9. 2012
  7. ncbi Study of the cytotoxic activity of beauvericin and fusaproliferin and bioavailability in vitro on Caco-2 cells
    A Prosperini
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem Toxicol 50:2356-61. 2012
  8. ncbi Comparative cytotoxicity study of enniatins A, A₁, A₂, B, B₁, B₄ and J₃ on Caco-2 cells, Hep-G₂ and HT-29
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem Toxicol 49:2464-9. 2011
  9. ncbi Reactive oxygen species induced by beauvericin, patulin and zearalenone in CHO-K1 cells
    E Ferrer
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Toxicol In Vitro 23:1504-9. 2009
  10. ncbi Isolation and purification of enniatins A, A(1), B, B(1), produced by Fusarium tricinctum in solid culture, and cytotoxicity effects on Caco-2 cells
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Toxicon 56:418-24. 2010

Collaborators

Detail Information

Publications10

  1. ncbi Genotoxicity of six pesticides by Salmonella mutagenicity test and SOS chromotest
    M J Ruiz
    Laboratori de Toxicologia, Facultat de Formàcia, Universitat de Valencia, Spain
    Mutat Res 390:245-55. 1997
    ....
  2. ncbi Toxicological interactions between the mycotoxins beauvericin, deoxynivalenol and T-2 toxin in CHO-K1 cells in vitro
    M J Ruiz
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Toxicon 58:315-26. 2011
    ....
  3. ncbi Cytotoxic effects of mycotoxin combinations in mammalian kidney cells
    Maria Jose Ruiz
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Food Chem Toxicol 49:2718-24. 2011
    ..43-5.89), DON+T-2 toxin (3.13-7.62) and BEA+DON+T-2 toxin (1.32-2.68) for 24, 48 and 72h produced antagonistic effects in Vero cells. The highest antagonistic effect in Vero cells was observed with binary DON and T-2 toxin mixture...
  4. ncbi Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic
    M J Ruiz
    Departamento de Fisiologia, Facultat de Farmacia, Universitat de Valencia, Valencia, Spain
    J Agric Food Chem 57:3180-6. 2009
    ..Biochemical parameters were not affected. Histopathological examination revealed no alterations in clinical signs or organ weight at any dose...
  5. ncbi Study of the potential toxicity of enniatins A, A(1), B, B(1) by evaluation of duodenal and colonic bioavailability applying an in vitro method by Caco-2 cells
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Valencia, Spain
    Toxicon 59:1-11. 2012
    ..3% for EN A, from 40.8 to 50.0% for EN A(1), from 47.7 to 55.0% for EN B, and from 52.4 to 57.4% for En B(1). The highest duodenal and colonic bioavailability was observed after Caco-2 cells exposed to EN A, ENs B and B(1), respectively...
  6. ncbi Co-occurrence and risk assessment of mycotoxins in food and diet from Mediterranean area
    A B Serrano
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem 135:423-9. 2012
    ....
  7. ncbi Study of the cytotoxic activity of beauvericin and fusaproliferin and bioavailability in vitro on Caco-2 cells
    A Prosperini
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem Toxicol 50:2356-61. 2012
    ..BEA bioavailability was variable from 50.1% to 54.3%, whereas FUS presented a bioavailability variable from 80.2% to 83.2%. Results obtained demonstrated a potential risk for human health...
  8. ncbi Comparative cytotoxicity study of enniatins A, A₁, A₂, B, B₁, B₄ and J₃ on Caco-2 cells, Hep-G₂ and HT-29
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Food Chem Toxicol 49:2464-9. 2011
    ..7 ± 0.7 to 11.5 ± 5.3 μM) and B(4) (IC(50) of 4.5 ± 2.9-15.0 ± 4.0 μM). In summary, this study demonstrated that ENs can exert toxic activity at low micromolar concentrations in mammalian cells...
  9. ncbi Reactive oxygen species induced by beauvericin, patulin and zearalenone in CHO-K1 cells
    E Ferrer
    Laboratori de Toxicologia, Facultat de Farmacia, Universitat de Valencia, Av Vicent Andres Estelles, 46100 Burjassot, Valencia, Spain
    Toxicol In Vitro 23:1504-9. 2009
    ..These data suggested that cytotoxicity and ROS generation are mechanisms of mycotoxins mediated toxicity...
  10. ncbi Isolation and purification of enniatins A, A(1), B, B(1), produced by Fusarium tricinctum in solid culture, and cytotoxicity effects on Caco-2 cells
    G Meca
    Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Toxicon 56:418-24. 2010
    ..5 microM. This study indicates that ENs, fungal metabolites that are commonly found in corn and in general in product composed by corn, may have a toxic potential for human health...