Genomes and Genes
Affiliation: University of Valladolid
- Training and professional profile of retinologists in Spain: Retina 2 project, Report 4J Carlos Pastor
University Institute of Applied Ophthalmobiology IOBA, Retina Group
Clin Ophthalmol 5:483-90. 2011..Before developing a framework for such a system, we established the learning and professional profiles of Spanish ophthalmologists dedicated to medical retina and vitreoretina subspecialties...
- Development of predictive models of proliferative vitreoretinopathy based on genetic variables: the Retina 4 projectJimena Rojas
Department of Ophthalmology, University of Valladolid, IOBA Institute for Research in Ophthalmobiology, Valladolid, Spain
Invest Ophthalmol Vis Sci 50:2384-90. 2009....
- Predicting proliferative vitreoretinopathy: temporal and external validation of models based on genetic and clinical variablesJimena Rojas
IOBA Eye Institute, University of Valladolid, Valladolid, Spain
Br J Ophthalmol 99:41-8. 2015..To validate three models for predicting proliferative vitreoretinopathy (PVR) based on the analysis of genotypic data and relevant clinical characteristics...
- The T309G MDM2 gene polymorphism is a novel risk factor for proliferative vitreoretinopathySalvador Pastor-Idoate
Instituto de Oftalmobiología IOBA Retina Group, University of Valladolid, Valladolid, Spain Unidad de Medicina Molecular, Departamento de Medicina, University of Salamanca, Salamanca, Spain
PLoS ONE 8:e82283. 2013..8-19.1). Results indicate that the G allele of rs2279744 is associated with a higher risk of developing PVR in patients undergoing a RD surgery. Further studies are necessary to understand the role of this SNP in the development of PVR. ..
- BAX and BCL-2 polymorphisms, as predictors of proliferative vitreoretinopathy development in patients suffering retinal detachment: the Retina 4 projectSalvador Pastor-Idoate
Instituto de Oftalmobiología Aplicada IOBA Retina Group, University of Valladolid, Valladolid, Spain
Acta Ophthalmol 93:e541-9. 2015....
- A genetic case-control study confirms the implication of SMAD7 and TNF locus in the development of proliferative vitreoretinopathyJimena Rojas
Institute of Applied Ophthalmolbiology IOBA Eye Institute, University of Valladolid, Spain
Invest Ophthalmol Vis Sci 54:1665-78. 2013..The objective of this study was to analyze the genetic contribution to PVR in patients undergoing RD surgery, the Retina 4 Project...
- The p53 codon 72 polymorphism (rs1042522) is associated with proliferative vitreoretinopathy: the Retina 4 ProjectSalvador Pastor-Idoate
Department of Ophthalmology, University Hospital of Valladolid, Valladolid, Spain
Ophthalmology 120:623-8. 2013..To compare the distribution of a p53 gene polymorphism among European subjects undergoing primary retinal detachment (RD) surgery in relation to the development of proliferative vitreoretinopathy (PVR)...
- A propensity score matching application: indications and results of adding scleral buckle to vitrectomy: The Retina 1 Project: Report 3Maria R Sanabria
IOBA, University of Valladolid, Valladolid, Spain
Eur J Ophthalmol 22:244-53. 2012....
- A strong genetic association between the tumor necrosis factor locus and proliferative vitreoretinopathy: the retina 4 projectJimena Rojas
Institute of Applied Ophthalmobiology, University of Valladolid, Spain
Ophthalmology 117:2417-2423.e1-2. 2010..To assess the genetic contribution to proliferative vitreoretinopathy (PVR) and report the strong association observed in the tumor necrosis factor (TNF) locus...
- Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical consequencesJ Carlos Pastor
Retina Group, IOBA Eye Institute, University of Valladolid, Valladolid, Spain Department of Ophthalmology, Hospital Clinico Universitario de Valladolid, Valladolid, Spain Electronic address
Prog Retin Eye Res 51:125-55. 2016..Finally, we provide some recommendations for future classification of PVR and for designing comparable protocols for testing new drugs or techniques. ..