Tomás Pérez-Ruiz

Summary

Affiliation: University of Murcia
Country: Spain

Publications

  1. ncbi request reprint Flow-injection extraction-spectrophotometric method for the determination of ranitidine in pharmaceutical preparations
    T Perez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    J Pharm Biomed Anal 26:609-15. 2001
  2. ncbi request reprint Automatic determination of phylloquinone in vegetables and fruits using on-line photochemical reduction and fluorescence detection via solid phase extraction and flow injection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    Anal Bioanal Chem 384:280-5. 2006
  3. ncbi request reprint Flow injection chemiluminescent determination of amiodarone in pharmaceutical preparations using photogenerated tris(2,2'-bipyridyl)ruthenium(III)
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 42:143-7. 2006
  4. ncbi request reprint Development and validation of a capillary electrophoresis method with laser-induced fluorescence detection for the determination of captopril in human urine and pharmaceutical preparations
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Murcia, Spain
    Electrophoresis 27:2310-6. 2006
  5. ncbi request reprint High-performance liquid chromatography: photochemical reduction in aerobic conditions for determination of K vitamins using fluorescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, E 30071 Murcia, Spain
    J Chromatogr A 1141:67-72. 2007
  6. ncbi request reprint Determination of propoxur in environmental samples by automated solid-phase extraction followed by flow-injection analysis with tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    Anal Chim Acta 584:275-80. 2007
  7. ncbi request reprint Determination of N-methylcarbamate pesticides in environmental samples by an automated solid-phase extraction and liquid chromatographic method based on post-column photolysis and chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    J Chromatogr A 1164:174-80. 2007
  8. ncbi request reprint High-performance liquid chromatography-post-column chemiluminescence determination of aminopolycarboxylic acids at low concentration levels using tris(2,2'-bipyridyl)ruthenium(III)
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Chromatogr A 1169:151-7. 2007
  9. doi request reprint Chemiluminescent determination of EDTA and related compounds using tris(2,2'-bipyridyl)ruthenium(III) photogenerated on-line
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    Anal Bioanal Chem 391:1451-7. 2008
  10. doi request reprint Simultaneous determination of amiodarone and its metabolite desethylamiodarone by high-performance liquid chromatography with chemiluminescent detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    Anal Chim Acta 623:89-95. 2008

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Flow-injection extraction-spectrophotometric method for the determination of ranitidine in pharmaceutical preparations
    T Perez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    J Pharm Biomed Anal 26:609-15. 2001
    ..The method was satisfactorily applied to the determination of ranitidine in pharmaceutical preparations and the recovery was quantitative and no interferences from excipients were observed...
  2. ncbi request reprint Automatic determination of phylloquinone in vegetables and fruits using on-line photochemical reduction and fluorescence detection via solid phase extraction and flow injection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    Anal Bioanal Chem 384:280-5. 2006
    ..Extractions were made with hexane, and an automated solid phase extraction system was used to purify the sample extracts prior to injection into the flow injection manifold...
  3. ncbi request reprint Flow injection chemiluminescent determination of amiodarone in pharmaceutical preparations using photogenerated tris(2,2'-bipyridyl)ruthenium(III)
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 42:143-7. 2006
    ..8%, respectively) and a reagent consumption of only 0.37 micromol (0.27 mg) of Ru(bpy)(3)Cl(2) x 6H(2)O per determination. The method was successfully applied to the determination of amiodarone in commercial pharmaceutical formulations...
  4. ncbi request reprint Development and validation of a capillary electrophoresis method with laser-induced fluorescence detection for the determination of captopril in human urine and pharmaceutical preparations
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Murcia, Spain
    Electrophoresis 27:2310-6. 2006
    ..86 and 1.16%, respectively, both expressed as RSD. The assay was successfully used for quantification of captopril in some marketed pharmaceutical preparations and urine samples...
  5. ncbi request reprint High-performance liquid chromatography: photochemical reduction in aerobic conditions for determination of K vitamins using fluorescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, E 30071 Murcia, Spain
    J Chromatogr A 1141:67-72. 2007
    ..The determination of phylloquinone, menaquinone-4 and menadione in several real samples illustrates the potential of the photochemical detection system...
  6. ncbi request reprint Determination of propoxur in environmental samples by automated solid-phase extraction followed by flow-injection analysis with tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    Anal Chim Acta 584:275-80. 2007
    ..This SPE-FI-CL arrangement provides a detection limit as low as 5 ng L(-1) using only 500 mL of sample. In the analysis of fruits and vegetables, the detection limit was about 10 microg kg(-1)...
  7. ncbi request reprint Determination of N-methylcarbamate pesticides in environmental samples by an automated solid-phase extraction and liquid chromatographic method based on post-column photolysis and chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    J Chromatogr A 1164:174-80. 2007
    ..Detection limits were within the range 3.9-36.7 ngl(-1) for water samples and 0.5-4.7 microgkg(-1) for fruits...
  8. ncbi request reprint High-performance liquid chromatography-post-column chemiluminescence determination of aminopolycarboxylic acids at low concentration levels using tris(2,2'-bipyridyl)ruthenium(III)
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Chromatogr A 1169:151-7. 2007
    ..The lowest amounts measurable were: 75 pg for NTA, 0.7 ng for EDDS, 0.8 ng for DTPA and 12ng for EDTA. The method was also applied for the EDTA assay in canned foods...
  9. doi request reprint Chemiluminescent determination of EDTA and related compounds using tris(2,2'-bipyridyl)ruthenium(III) photogenerated on-line
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071, Murcia, Spain
    Anal Bioanal Chem 391:1451-7. 2008
    ..5%. The method was successfully applied to the determination of EDTA in ophthalmic collyrium and sauce samples. The method is also useful for determining other aminopolycarboxylic acids, such as NTA, EGTA, DTPA, DCTA and EDDS...
  10. doi request reprint Simultaneous determination of amiodarone and its metabolite desethylamiodarone by high-performance liquid chromatography with chemiluminescent detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    Anal Chim Acta 623:89-95. 2008
    ..9% relative standard deviation (R.S.D.) (n=10) and 1.6% R.S.D. (n=15), respectively, were obtained. The method was applied successfully to the determination of these compounds in serum and pharmaceutical formulations...
  11. doi request reprint A sensitive post-column photochemical derivatization/fluorimetric detection system for HPLC determination of bisphosphonates
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Chromatogr A 1216:1312-8. 2009
    ..05 mol L(-1) ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid...
  12. ncbi request reprint Determination of omeprazole, hydroxyomeprazole and omeprazole sulfone using automated solid phase extraction and micellar electrokinetic capillary chromatography
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Campus de Espinardo, 30071 Murcia, Spain
    J Pharm Biomed Anal 42:100-6. 2006
    ..The validated method was applied to the determination of omeprazole in pharmaceutical preparations and for the analysis of plasma samples obtained from three volunteers who received oral doses of omeprazole...
  13. ncbi request reprint Automated solid-phase extraction and high-performance liquid chromatographic determination of nitrosamines using post-column photolysis and tris(2,2'-bipyridyl) ruthenium(III) chemiluminescence
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, E 30071 Murcia, Spain
    J Chromatogr A 1077:49-56. 2005
    ..An automated solid-phase extraction (SPE) system was used in conjunction with HPLC to determine nitrosamine residues in waters. Detection limits within the range 0.10-3.0 ng l(-1) were achieved for only 250 ml of sample...
  14. ncbi request reprint Migration behaviour and separation of acetaminophen and p-aminophenol in capillary zone electrophoresis: analysis of drugs based on acetaminophen
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, University of Murcia, Campus de Espinardo, 30071 Murcia, Spain
    J Pharm Biomed Anal 38:87-93. 2005
    ..999. The sensitivity of detection is 4.2 ng ml-1 for acetaminophen and 11.2 ng ml-1 for p-aminophenol. The method was applied to the analysis of various commercially available acetaminophen dosage forms with recoveries of 98.4-100.7%...
  15. ncbi request reprint Chemiluminescence determination of carbofuran and promecarb by flow injection analysis using two photochemical reactions
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain
    Analyst 127:1526-30. 2002
    ..The sample throughput was 200 injections per h. The reliability of the method for routine analysis of these pesticides in water, soil and grains is demonstrated...
  16. ncbi request reprint Spectrofluorimetric determination of formaldehyde by a flow-injection method based on its catalytic effect on the acridine yellow-bromate reaction
    T Perez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    Anal Bioanal Chem 375:661-5. 2003
    ..The accuracy of the method was confirmed by comparing the results with those obtained using the standard acetylacetone method...
  17. ncbi request reprint Determination of allopurinol by micelle-stabilised room-temperature phosphorescence in real samples
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 32:225-31. 2003
    ..The results of the analysis of several pharmaceutical preparations were satisfactory. The clinical applicability of this procedure has been tested by analysing allopurinol in urine samples...
  18. ncbi request reprint High-performance liquid chromatographic separation and quantification of citric, lactic, malic, oxalic and tartaric acids using a post-column photochemical reaction and chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry University of Murcia, 30071 Murcia, Spain
    J Chromatogr A 1026:57-64. 2004
    ..The applicability of the assay was demonstrated by analysing these compounds in real samples such as milk, fruit juices, soft drinks, wine and beer...
  19. ncbi request reprint Successive determination of thiamine and ascorbic acid in pharmaceuticals by flow injection analysis
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 34:551-7. 2004
    ..The calibration graphs were linear over the range 2-100 microg ml(-1) for thiamine and 5-100 microg ml(-1) for ascorbic acid. The throughput was 25 samples per hour...
  20. ncbi request reprint An ultrasensitive method for the determination of thiouracil and phenylthiouracil using capillary zone electrophoresis and laser-induced fluorescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Campus de Espinardo, Murcia, Spain
    Electrophoresis 26:2384-90. 2005
    ..0) and quantified by fluorescence detection. The linearity range, precision, recovery, and detection limits were determined, and the method was shown to be applicable for the determination of TU and PhTU in spiked feed samples and urine...
  21. doi request reprint Simultaneous determination of thiamine and its phosphate esters by a liquid chromatographic method based on post-column photolysis and chemiluminescence detection
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 50:315-9. 2009
    ..14% relative standard deviation (RSD) (n=10) and 1.86% RSD (n=15), respectively, were obtained. The method was successfully applied to the determination of the thiamines in pharmaceutical preparations and baby foods...
  22. ncbi request reprint Fluorimetric determination of arsanilic acid by flow-injection analysis using on-line photo-oxidation
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain
    Anal Bioanal Chem 372:387-90. 2002
    ..999. The detection limit was 0.01 microg mL(-1) and the sample throughput was 55 samples h(-1). The applicability of the method was demonstrated by determining arsanilic acid in animal foodstuffs and water...
  23. ncbi request reprint Direct determination of ranitidine and famotidine by CE in serum, urine and pharmaceutical formulations
    Tomás Pérez-Ruiz
    Faculty of Chemistry, Department of Analytical Chemistry, University of Murcia, 30071, Murcia, Spain
    J Pharm Biomed Anal 30:1055-61. 2002
    ..5 was found to provide a very efficient and stable electrophoretic system for the analysis of both drugs. The detection limits obtained were 0.088 microgram ml(-1) for RANT and 0.16 microgram ml(-1) for FAMT...
  24. ncbi request reprint Development of a capillary electrophoresis method for the determination of allopurinol and its active metabolite oxypurinol
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, University of Murcia, 30071, Murcia, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 798:303-8. 2003
    ..The applicability of the assay was demonstrated by analyzing these compounds in serum and allopurinol in commercial pharmaceutical preparations...
  25. ncbi request reprint Development and validation of a quantitative assay for raloxifene by capillary electrophoresis
    Tomás Pérez-Ruiz
    Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071 Murcia, Spain
    J Pharm Biomed Anal 34:891-7. 2004
    ..The applicability of the assay was demonstrated by analyzing this drug in human plasma and pharmaceutical preparations...