E Piazuelo

Summary

Affiliation: University of Zaragoza
Country: Spain

Publications

  1. doi request reprint Acetylsalicylic Acid Exhibits Antitumor Effects in Esophageal Adenocarcinoma Cells In Vitro and In Vivo
    Elena Piazuelo
    IIS Aragón, Saragossa, Spain
    Dig Dis Sci 61:2896-907. 2016
  2. ncbi request reprint Characterization of the prostaglandin E2 pathway in a rat model of esophageal adenocarcinoma
    E Piazuelo
    IIS Aragón, Aragon Institute of Health Scineces, Zaragoza, Spain
    Curr Cancer Drug Targets 12:132-43. 2012
  3. doi request reprint A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
    Clin Ther 30:121-30. 2008
  4. ncbi request reprint Effects of selective PGE2 receptor antagonists in esophageal adenocarcinoma cells derived from Barrett's esophagus
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
    Prostaglandins Other Lipid Mediat 81:150-61. 2006
  5. pmc Superoxide dismutase prevents development of adenocarcinoma in a rat model of Barrett's esophagus
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Unidad Mixta de Investigacion, Zaragoza, Spain
    World J Gastroenterol 11:7436-43. 2005
  6. ncbi request reprint [Defense of the esophageal mucosa as a therapeutic target in gastroesophageal reflux disease]
    E Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Espana
    Gastroenterol Hepatol 27:274-84. 2004
  7. doi request reprint Prostaglandin EP2 receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma
    P Jimenez
    CIBER Enfermedades Hepáticas y Digestivas CIBERehd, University Hospital, Zaragoza, Spain
    Aliment Pharmacol Ther 31:440-51. 2010
  8. ncbi request reprint TGFB1 gene polymorphisms: their relevance in the susceptibility to Helicobacter pylori-related diseases
    M A Garcia-Gonzalez
    Unidad Mixta de Investigacion, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain
    Genes Immun 7:640-6. 2006
  9. ncbi request reprint Effects of long-term cyclo-oxygenase 2 selective and acid inhibition on Barrett's oesophagus
    A Lanas
    Service of Digestive Diseases, University Hospital, Instituto Aragones de Ciencias de la Salud, CIBERehd, Zaragoza, Spain
    Aliment Pharmacol Ther 26:913-23. 2007
  10. ncbi request reprint COX-2 inhibition in esophagitis, Barrett's esophagus and esophageal cancer
    E Piazuelo
    Instituto Aragones de Ciencias de la Salud, Hospital Clinico Universitario, Zafagoza, Spain
    Curr Pharm Des 9:2267-80. 2003

Collaborators

Detail Information

Publications16

  1. doi request reprint Acetylsalicylic Acid Exhibits Antitumor Effects in Esophageal Adenocarcinoma Cells In Vitro and In Vivo
    Elena Piazuelo
    IIS Aragón, Saragossa, Spain
    Dig Dis Sci 61:2896-907. 2016
    ..Recent observational studies have shown therapeutic benefits of acetylsalicylic acid (ASA) in several types of cancer. We examined whether ASA exerts antitumor activity in esophageal adenocarcinoma (EAC)...
  2. ncbi request reprint Characterization of the prostaglandin E2 pathway in a rat model of esophageal adenocarcinoma
    E Piazuelo
    IIS Aragón, Aragon Institute of Health Scineces, Zaragoza, Spain
    Curr Cancer Drug Targets 12:132-43. 2012
    ..Esophagojejunostomy with gastric preservation was performed in wistar rats to induce gastroduodenal reflux. Rats were sacrificed 2 or 4 months after surgery. Nine non-operated rats were used to obtain normal (control) esophageal tissues...
  3. doi request reprint A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
    Clin Ther 30:121-30. 2008
    ..Previous studies have reported a potential genetic predisposition to NSAID-related upper gastrointestinal (GI) bleeding...
  4. ncbi request reprint Effects of selective PGE2 receptor antagonists in esophageal adenocarcinoma cells derived from Barrett's esophagus
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
    Prostaglandins Other Lipid Mediat 81:150-61. 2006
    ..These findings suggest a potential role for EP selective antagonists in the treatment of esophageal adenocarcinoma...
  5. pmc Superoxide dismutase prevents development of adenocarcinoma in a rat model of Barrett's esophagus
    Elena Piazuelo
    Instituto Aragones de Ciencias de la Salud, Unidad Mixta de Investigacion, Zaragoza, Spain
    World J Gastroenterol 11:7436-43. 2005
    ..To test whether antioxidant treatment could prevent the progression of Barrett's esophagus to adenocarcinoma...
  6. ncbi request reprint [Defense of the esophageal mucosa as a therapeutic target in gastroesophageal reflux disease]
    E Piazuelo
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Espana
    Gastroenterol Hepatol 27:274-84. 2004
  7. doi request reprint Prostaglandin EP2 receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma
    P Jimenez
    CIBER Enfermedades Hepáticas y Digestivas CIBERehd, University Hospital, Zaragoza, Spain
    Aliment Pharmacol Ther 31:440-51. 2010
    ..Accumulating evidence suggests that cyclooxygenase-2 (COX-2)-derived prostaglandin E2 (PGE2) is involved in oesophageal adenocarcinogenesis. PGE2 exerts its biological action by binding to specific receptors (EP1, EP2, EP3 and EP4)...
  8. ncbi request reprint TGFB1 gene polymorphisms: their relevance in the susceptibility to Helicobacter pylori-related diseases
    M A Garcia-Gonzalez
    Unidad Mixta de Investigacion, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain
    Genes Immun 7:640-6. 2006
    ..15-0.68; P=0.003). Our results show that the TGFB1 T+869C gene polymorphism is involved in the susceptibility to DU and provide further evidence that host genetic factors play a key role in the pathogenesis of H. pylori-related diseases...
  9. ncbi request reprint Effects of long-term cyclo-oxygenase 2 selective and acid inhibition on Barrett's oesophagus
    A Lanas
    Service of Digestive Diseases, University Hospital, Instituto Aragones de Ciencias de la Salud, CIBERehd, Zaragoza, Spain
    Aliment Pharmacol Ther 26:913-23. 2007
    ..There is an overexpression of cyclo-oxygenase 2 (COX-2) in Barrett's oesophagus (BO)...
  10. ncbi request reprint COX-2 inhibition in esophagitis, Barrett's esophagus and esophageal cancer
    E Piazuelo
    Instituto Aragones de Ciencias de la Salud, Hospital Clinico Universitario, Zafagoza, Spain
    Curr Pharm Des 9:2267-80. 2003
    ..Further studies are necessary in order to better understand factors involved in COX-2 up-regulation and mechanisms of COX-2 associated tumorigenesis in the esophagus...
  11. ncbi request reprint Collagen secretion by human gastric and skin fibroblasts: implications for ulcer healing
    A Lanas
    Unidad Mixta de Investigacion, Hospital Clinico Universitario, Universidad de Zaragoza, Espana
    Eur Surg Res 30:48-54. 1998
    ..These data provide new insights into the wound-healing process...
  12. doi request reprint Cystatin C level as a predictor of death and cardiovascular events after liver transplantation
    V Bernal
    Department of Hepatology and Gastroenterology, University Hospital Lozano Blesa, Zaragoza, Spain
    Transplant Proc 43:732-4. 2011
    ..Our aims were to investigate plasma Cys concentrations for the detection of moderately impaired renal function and its association with mortality and cardiovascular events among cirrhotic patients after liver transplantation (OLT)...
  13. ncbi request reprint Prevention of cancer in the upper gastrointestinal tract with COX-inhibition. Still an option?
    Pilar Jimenez
    Instituto Aragones de Ciencias de la Salud, Service of Gastroenterology, Hospital Clinico Universitario, Zaragoza, Spain
    Curr Pharm Des 13:2261-73. 2007
    ..Taken together, these data indicate that a re-evaluation of potential chemoprevention strategies for cancers of the upper gastrointestinal tract needs to be considered...
  14. pmc Free radicals and antioxidant systems in reflux esophagitis and Barrett's esophagus
    Pilar Jimenez
    Aragonés Institute of Health Sciences, and Gastroenterology Service, Lozano Blesa University Hospital Clinic, Avenida San Juan Bosco, C Domingo Miral, s n 15 50009 Zaragoza, Spain
    World J Gastroenterol 11:2697-703. 2005
    ..Experimental studies suggest that free radicals are involved in acid and pepsin-induced damage of esophageal mucosa. The profile and balance between free radicals and antioxidant systems in human esophagitis are unknown...
  15. ncbi request reprint Genomic rearrangements in MSH2 and MLH1 are rare mutational events in Spanish patients with hereditary nonpolyposis colorectal cancer
    Sergi Castellvi-Bel
    Gastroenterology Department, Institut de Malalties Digestives, IDIBAPS, Barcelona, Catalonia, Spain
    Cancer Lett 225:93-8. 2005
    ..These results showed that MSH2/MLH1 rearrangements in Spanish patients at risk for HNPCC seem to be a less frequent mutational event than in other populations...
  16. ncbi request reprint Gastric cancer susceptibility is not linked to pro-and anti-inflammatory cytokine gene polymorphisms in whites: a Nationwide Multicenter Study in Spain
    María Asunción García-Gonzalez
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
    Am J Gastroenterol 102:1878-92. 2007
    ..Our goal was to evaluate the influence of Helicobacter pylori (H. pylori) infection and host genetic factors on GC susceptibility in a population of Spanish white GC patients...