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Genomes and Genes | J NacherSummaryAffiliation: University of Valencia Country: Spain Publications
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Publications
Chronic fluoxetine treatment in middle-aged rats induces changes in the expression of plasticity-related molecules and in neurogenesisRamón Guirado
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Dpt, Universitat de Valencia, Spain
BMC Neurosci 13:5. 2012..PSA-NCAM is expressed in immature neurons and in a subpopulation of mature interneurons and its expression is modulated by antidepressants in the telencephalon of young-adult rodents...
Expression of the transcription factor Pax 6 in the adult rat dentate gyrusJuan Nacher
Neurobiology, Cell Biology Department, Universitat de Valencia, Burjassot, Spain
J Neurosci Res 81:753-61. 2005..However, the expression of Pax 6 in astrocytes and certain mature neurons may indicate the existence of other roles for this transcription factor in this telencephalic region...
Chronic non-invasive glucocorticoid administration decreases polysialylated neural cell adhesion molecule expression in the adult rat dentate gyrusJuan Nacher
Neurobiology, Cell Biology Department, Universitat de Valencia, Dr Moliner, 50, Burjassot 46100, Spain
Neurosci Lett 370:40-4. 2004..Because CORT treatment reduces but does not eliminate PSA-NCAM expression, the present results do not exclude a permissive role for PSA-NCAM in CORT or CRS-induced structural plasticity in hippocampus...
NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampusJuan Nacher
Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Neurobiol Aging 24:273-84. 2003..Injection of the NMDA receptor antagonist to aged rats increases significantly the number of proliferating cells, new neurons and radial glia-like cells in the hippocampus...
CRMP-4 expression in the adult cerebral cortex and other telencephalic areas of the lizard Podarcis hispanicaJuan Nacher
Neurobiologia, Biologia Celular, Facultad de Ciencias Biologicas, Universidad de Valencia, 46100 Burjassot, Valencia, Spain
Brain Res Dev Brain Res 139:285-94. 2002..Our results show for the first time the expression of CRMP-4 in a reptile brain, where it appears to be expressed in regions where adult neurogenesis and/or neurite outgrowth occur...
Distribution of PSA-NCAM expression in the amygdala of the adult ratJ Nacher
Laboratory of Neuroendocrinology, Rockefeller University, New York, NY 10021, USA
Neuroscience 113:479-84. 2002..PSA-NCAM expression in the lateral amygdala could indicate its participation in the plastic events that lead to the generation of emotional memories such as those related to fear conditioning...
Divergent impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid expression in immature neurons and interneurons of the adult cerebral cortexJ Nacher
Cell Biology Department, Universitat de Valencia, Burjassot, Spain
Neuroscience 167:825-37. 2010..However, many of the immature granule neurons showed aberrant locations and morphology, suggesting a role of ST8SiaII in their terminal differentiation...
Non-granule PSA-NCAM immunoreactive neurons in the rat hippocampusJuan Nacher
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, Rockefeller University, York Avenue 1230, New York, NY 10021, USA
Brain Res 930:1-11. 2002..The presence of the polysialylated form of NCAM in these neurons could indicate that they are undergoing continuous remodeling during adulthood and may have an important role in hippocampal structural plasticity...
PSA-NCAM expression in the piriform cortex of the adult rat. Modulation by NMDA receptor antagonist administrationJuan Nacher
Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Brain Res 927:111-21. 2002..Similar to the hippocampus, NMDA receptors appear to play a critical role in these processes in the adult piriform cortex...
Doublecortin expression in the adult rat telencephalonJ Nacher
Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10021, USA
Eur J Neurosci 14:629-44. 2001..Given these results, we hypothesize that DCX expression in differentiated neurons could be related to its capacity for microtubule reorganization and that this fact could be linked to axonal outgrowth or synaptogenesis...
NMDA receptor antagonist treatment induces a long-lasting increase in the number of proliferating cells, PSA-NCAM-immunoreactive granule neurons and radial glia in the adult rat dentate gyrusJ Nacher
Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10021, USA
Eur J Neurosci 13:512-20. 2001..Thus, NMDA receptor antagonist treatment serves as a valuable tool to increase neurogenesis in the adult hippocampus without undesirable collateral deleterious effects...
Chronic restraint stress and chronic corticosterone treatment modulate differentially the expression of molecules related to structural plasticity in the adult rat piriform cortexJ Nacher
Laboratory of Neuroendocrinology, Rockefeller University, New York, NY 10021, USA
Neuroscience 126:503-9. 2004..This is a potential mechanism by which stress and corticosterone modulate functions of this limbic region, such as its participation in olfactory memory...
Chronic antidepressant treatment induces contrasting patterns of synaptophysin and PSA-NCAM expression in different regions of the adult rat telencephalonE Varea
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Department, Universitat de Valencia, Spain
Eur Neuropsychopharmacol 17:546-57. 2007..The expression of these molecules is also affected in the entorhinal, the visual and the somatosensory cortices...
N-methyl-d-aspartate receptor expression during adult neurogenesis in the rat dentate gyrusJ Nacher
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Department, Universitat de Valencia, Dr Moliner 50, Burjassot 46100, Spain
Neuroscience 144:855-64. 2007..However, an indirect effect through NMDA receptors located in other cell types should not be excluded...
Widespread expression of rat collapsin response-mediated protein 4 in the telencephalon and other areas of the adult rat central nervous systemJ Nacher
Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
J Comp Neurol 424:628-39. 2000..These cells did not express neuronal, astroglial, or microglial markers, although some of them also were immunoreactive for rip antibody, suggesting an oligodendroglial lineage...
Effects of chronic fluoxetine treatment on the rat somatosensory cortex: activation and induction of neuronal structural plasticityR Guirado
Cell Biology Department, Neurobiology Unit and Program in Basic and Applied Neurosciences, Universitat de Valencia, Spain
Neurosci Lett 457:12-5. 2009..These results indicate that, apart from the medial prefrontal cortex or the hippocampus, other cortical regions can respond to chronic antidepressant treatment undergoing neuronal structural plasticity...
Synaptic connectivity of serotonergic axons in the olfactory glomeruli of the rat olfactory bulbF J Gracia-Llanes
Departamento de Biologia Celular, Facultad de Ciencias Biologicas, Universidad de Valencia, Burjasot, Valencia, Spain
Neuroscience 169:770-80. 2010..Altogether, our results suggest a complex action of the serotonergic system in the modulation of the bulbar circuitry...
PSA-NCAM expression in the rat medial prefrontal cortexE Varea
Neurobiology, Cell Biology Department, Universitat de Valencia, Dr Moliner, 50, 46100 Burjassot, Valencia, Spain
Neuroscience 136:435-43. 2005....
Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down's syndromeD Pérez-Cremades
Department of Cell Biology, University of Valencia, Dr Moliner Street, 50, 46100 Burjassot, Valencia, Spain
J Neural Transm 117:445-55. 2010....
Distribution of the A3 subunit of the cyclic nucleotide-gated ion channels in the main olfactory bulb of the ratM Gutierrez-Mecinas
Departamento de Biologia Celular, Unidad de Neurobiologia, Facultad de Ciencias Biologicas, Universidad de Valencia, Street Dr Moliner 50, Burjasot, Spain
Neuroscience 153:1164-76. 2008..Moreover, they can be involved in the function of the ensheathing glia and in the radial migration of immature cells through the bulbar layers...
"Arrested development". Immature, but not recently generated, neurons in the adult brainM Á Gómez-Climent
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Dpt, Universitat de Valencia, Spain
Arch Ital Biol 148:159-72. 2010..The review is mainly focused on the population of immature neurons located in the layer II of certain cortical regions, but we will also describe similar populations found in other regions of the peripheral and central nervous systems...
Differential expression of suppressors of cytokine signaling-1, -2, and -3 in the rat hippocampus after seizure: implications for neuromodulation by gp130 cytokinesD R Rosell
Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, Box 165, New York, NY 10021, USA
Neuroscience 122:349-58. 2003..Since in our previous study we did not detect cytokine receptor expression in non-principal cells, it is unclear what elicits SOCS-3 expression in this population...
Characterization of a population of tyrosine hydroxylase-containing interneurons in the external plexiform layer of the rat olfactory bulbT Liberia
Departamento de Biología Celular y Parasitología, Facultad de Ciencias Biologicas, Universidad de Valencia, C Dr Moliner, 50, E 46100 Burjassot, Spain
Neuroscience 217:140-53. 2012....
GABAergic basal forebrain afferents innervate selectively GABAergic targets in the main olfactory bulbF J Gracia-Llanes
Universidad de Valencia, Facultad de Ciencias Biologicas, Departamento de Biologia Celular, Unidad de Neurobiología Str Dr Moliner, 50 E 46 100 Burjasot Valencia, Spain
Neuroscience 170:913-22. 2010..Possible similarities of this pathway with the septo-hippocampal loop are discussed...
Olfactory bulbectomy, but not odor conditioned aversion, induces the differentiation of immature neurons in the adult rat piriform cortexM Á Gómez-Climent
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Department, Universitat de Valencia, Spain
Neuroscience 181:18-27. 2011..By contrast, these cells do not seem to play a crucial role in olfactory memory...
Spatiotemporal distribution of gp130 cytokines and their receptors after status epilepticus: comparison with neuronal degeneration and microglial activationD R Rosell
Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, Box 165, New York, NY 10021, USA
Neuroscience 122:329-48. 2003..Furthermore, we suggest that activity-dependent mechanisms may be involved in the regulation of cytokines expressed early, and that relatively late occurring cytokine expression may be elicited by injury-related stimuli...
Cytochemical techniques for zinc and heavy metals localization in nerve cellsCarlos Lopez-Garcia
Neurobiology, Department of Cell Biology, University of Valencia, 46100 Burjassot, Valencia, Spain
Microsc Res Tech 56:318-31. 2002....
The role of N-methyl-D-asparate receptors in neurogenesisJuan Nacher
Neurobiology Division, Department of Cell Biology, Universitat de Valencia, Dr. Moliner, 50 Burjassot 46100, Spain
Hippocampus 16:267-70. 2006....
The lizard cerebral cortex as a model to study neuronal regenerationCarlos Lopez-Garcia
Lab Neurobiologia Celular, Universidad de Valencia, Burjasot, Valencia, 46100, Spain
An Acad Bras Cienc 74:85-104. 2002..Thus the lizard cerebral cortex is a good model to study neuronal regeneration and the complex factors that regulate its neurogenetic, migratory and neo-synaptogenetic events...
Neural overexcitation and implication of NMDA and AMPA receptors in a mouse model of temporal lobe epilepsy implying zinc chelationMaría Isabel Domínguez
Universidad de Valencia, Facultad de Ciencias Biologicas, Departamento de Biologia Celular, Unidad de Neurobiologia, Burjasot, Spain
Epilepsia 47:887-99. 2006..The objective of this work was to study the developing of the lesion in this model of temporal lobe epilepsy and the implications of the different types of glutamate receptors...
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrusKara Pham
Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
Eur J Neurosci 17:879-86. 2003..These studies may help us understand the basis for hippocampal shrinkage and raise questions about the ultimate reversibility of the effects of chronic stress...
PSA-NCAM immunocytochemistry in the cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica: differential expression during medial cortex neuronal regenerationCarmen Ramirez-Castillejo
Neurobiologia, Biologia Celular, Facultad de Ciencias Biologicas, Universidad de Valencia, 46100 Burjassot, Spain
J Comp Neurol 453:145-56. 2002..Our results show for the first time the expression of PSA-NCAM in a reptile brain, where it appears to participate in the migration and differentiation of granule neurons during adult neurogenesis and regeneration...
Loss of input from the mossy cells blocks maturation of newly generated granule cellsAna Isabel Marqués Marí
Departamento de Biologia Celular, Unidad de Neurobiologia, Facultad de Ciencias Biologicas, Universidad de Valencia, E 46 100 Burjasot, Spain
Hippocampus 17:510-24. 2007..Thus, it is likely that the reorganization of the circuitry after the loss of the mossy cells facilitates the survival and incorporation of the newly generated granule cells...
