C Menendez

Summary

Affiliation: University of Barcelona
Country: Spain

Publications

  1. ncbi request reprint Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, Barcelona, Spain
    Lancet 350:844-50. 1997
  2. ncbi request reprint The effects of short-term iron supplementation on iron status in infants in malaria-endemic areas
    Clara Menendez
    Center for International Health y Departamento de Bioquimica Clínica Institut d Investigacions Biome diques August Pi i Sunyer Hospital Clinic, Villarroeal 170, E 08036, Barcelona, Spain
    Am J Trop Med Hyg 71:434-40. 2004
  3. ncbi request reprint Prevalence and mother-to-infant transmission of hepatitis viruses B, C, and E in Southern Tanzania
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    J Med Virol 58:215-20. 1999
  4. ncbi request reprint Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial
    D Schellenberg
    Unidad de Epidemiologia, Hospital Clinic, , Villarroel 170, 08036, Barcelona, Spain
    Lancet 357:1471-7. 2001
  5. pmc Cost-effectiveness of iron supplementation and malaria chemoprophylaxis in the prevention of anaemia and malaria among Tanzanian infants
    M Alonzo González
    Epidemiology and Biostatistics Unit, Hospital Clinic, Barcelona, Spain
    Bull World Health Organ 78:97-107. 2000
  6. ncbi request reprint Effect of malaria on soluble transferrin receptor levels in Tanzanian infants
    C Menendez
    , , Hospital Clinic, Barcelona, Spain
    Am J Trop Med Hyg 65:138-42. 2001
  7. doi request reprint Mother-to-child transmission of HIV-1: association with malaria prevention, anaemia and placental malaria
    D Naniche
    Barcelona Center for International Health Research CRESIB, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
    HIV Med 9:757-64. 2008
  8. ncbi request reprint The impact of placental malaria on gestational age and birth weight
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, E 08036, Barcelona, Spain
    J Infect Dis 181:1740-5. 2000
  9. ncbi request reprint The incidence of clinical malaria detected by active case detection in children in Ifakara, southern Tanzania
    D M Schellenberg
    Centro de Salud International, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Trans R Soc Trop Med Hyg 97:647-54. 2003
  10. ncbi request reprint Malaria-related anaemia
    C Menendez
    Unidad de Epidemiologia y Bioestadisica, Hospital Clinic, Barcelona, Spain
    Parasitol Today 16:469-76. 2000

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, Barcelona, Spain
    Lancet 350:844-50. 1997
    ..We undertook a randomised comparison of different strategies for control of anaemia and malaria in infants, including an assessment of the effect of iron supplementation on malaria susceptibility...
  2. ncbi request reprint The effects of short-term iron supplementation on iron status in infants in malaria-endemic areas
    Clara Menendez
    Center for International Health y Departamento de Bioquimica Clínica Institut d Investigacions Biome diques August Pi i Sunyer Hospital Clinic, Villarroeal 170, E 08036, Barcelona, Spain
    Am J Trop Med Hyg 71:434-40. 2004
    ..7% versus 37.3% at 12 months of age). We concluded that iron supplementation between the ages of 2-6 months improves iron status at least up to 12 months of age. Malaria infection does not contribute to iron deficiency...
  3. ncbi request reprint Prevalence and mother-to-infant transmission of hepatitis viruses B, C, and E in Southern Tanzania
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    J Med Virol 58:215-20. 1999
    ..The results of this study show for the first time in Africa that mother-to-infant transmission does not play a significant role in the acquisition of HCV infection...
  4. ncbi request reprint Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial
    D Schellenberg
    Unidad de Epidemiologia, Hospital Clinic, , Villarroel 170, 08036, Barcelona, Spain
    Lancet 357:1471-7. 2001
    ..Data are urgently needed to assess the potential cost-effectiveness of intermittent treatment in areas with different patterns of malaria endemicity...
  5. pmc Cost-effectiveness of iron supplementation and malaria chemoprophylaxis in the prevention of anaemia and malaria among Tanzanian infants
    M Alonzo González
    Epidemiology and Biostatistics Unit, Hospital Clinic, Barcelona, Spain
    Bull World Health Organ 78:97-107. 2000
    ..This economic analysis supports the inclusion of both malaria chemoprophylaxis and iron supplementation delivered through EPI as part of the control strategies for these major killers of infants in parts of sub-Saharan Africa...
  6. ncbi request reprint Effect of malaria on soluble transferrin receptor levels in Tanzanian infants
    C Menendez
    , , Hospital Clinic, Barcelona, Spain
    Am J Trop Med Hyg 65:138-42. 2001
    ..We conclude that the measurement of sTfR levels does not have a role in the diagnosis of iron deficiency anemia in young children exposed to malaria infection...
  7. doi request reprint Mother-to-child transmission of HIV-1: association with malaria prevention, anaemia and placental malaria
    D Naniche
    Barcelona Center for International Health Research CRESIB, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
    HIV Med 9:757-64. 2008
    ..Prevention of malaria in pregnancy could thus potentially affect MTCT of HIV. We studied the impact of intermittent preventive treatment during pregnancy (IPTp) on HIV-1 MTCT in southern Mozambique...
  8. ncbi request reprint The impact of placental malaria on gestational age and birth weight
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, E 08036, Barcelona, Spain
    J Infect Dis 181:1740-5. 2000
    ..This study also shows that placental malaria causes prematurity even in high-transmission areas. The impact of maternal malaria on infant mortality may be greater than was thought previously...
  9. ncbi request reprint The incidence of clinical malaria detected by active case detection in children in Ifakara, southern Tanzania
    D M Schellenberg
    Centro de Salud International, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Trans R Soc Trop Med Hyg 97:647-54. 2003
    ....
  10. ncbi request reprint Malaria-related anaemia
    C Menendez
    Unidad de Epidemiologia y Bioestadisica, Hospital Clinic, Barcelona, Spain
    Parasitol Today 16:469-76. 2000
    ..In this review, Clara Menendez, Alan Fleming and Pedro Alonso focus on recent advances in our knowledge of the pathophysiology, epidemiology, management and prevention of anaemia from falciparum malaria...
  11. ncbi request reprint Placental malaria is associated with cell-mediated inflammatory responses with selective absence of natural killer cells
    J Ordi
    Department of Pathology, Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS Hospital Clínic, Facultat de Medicina, Universitat de Barcelona, 08036 Barcelona, Spain
    J Infect Dis 183:1100-7. 2001
    ..These results indicate that placental malaria does not appear to be associated with cell-mediated immunosuppression. The role of the absence of NK cells in increased susceptibility to malaria needs to be further elucidated...
  12. ncbi request reprint Massive Plasmodium falciparum visceral sequestration: a cause of maternal death in Africa
    P Castillo
    Barcelona Centre for International Health Research CRESIB, Department of Pathology, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
    Clin Microbiol Infect 19:1035-41. 2013
    ..The PfIE sequestered in cerebral capillaries and the placenta coexist in these fatal cases. ..
  13. doi request reprint High HIV prevalence in a southern semi-rural area of Mozambique: a community-based survey
    R Gonzalez
    Barcelona Centre for International Heath Research CRESIB, Hospital Clinic, University of Barcelona, Barcelona, Spain
    HIV Med 13:581-8. 2012
    ..Southern African countries have borne the brunt of the HIV/AIDS pandemic. Monitoring epidemiological dynamics is critical to identify the populations at greatest risk of infection and to guide control strategies...
  14. ncbi request reprint The changing epidemiology of malaria in Ifakara Town, southern Tanzania
    David Schellenberg
    Centre for International Health, Institut de Investigaciones Biomedicas August Pi I Sunyer, Barcelona, Spain
    Trop Med Int Health 9:68-76. 2004
    ..Even in low/moderate malaria transmission settings, where older children suffer most malaria episodes, targeting effective malaria control at infants may produce important reductions in infant mortality caused by malaria...
  15. pmc The epidemiology of malaria in adults in a rural area of southern Mozambique
    Alfredo Mayor
    Center for International Health, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Malar J 6:3. 2007
    ..The present study was undertaken to investigate the clinical, parasitological and haematological status of adults exposed to malaria, and to characterize parasites in these individuals who progressively acquire protective immunity...
  16. pmc Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic IDIBAPS, Universitat de Barcelona, Barcelona, Spain
    PLoS Med 4:e242. 2007
    ..We investigated the role of age in disease incidence and the effects of chemoprophylaxis on clinical immunity development to Plasmodium falciparum during a randomised controlled trial...
  17. ncbi request reprint Malaria infection does not appear to modify the risk of bronchiolitis early in life
    Clara Menendez
    Unidad de Epidemiologia y Bioestadistica, Institut d Investigaciones Mediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Pediatr Infect Dis J 21:249-54. 2002
    ..Information on the role of parasites in this context is limited. Bronchiolitis in infancy has been linked with asthmatic symptoms later in childhood, although the underlying cause of this association is unknown...
  18. ncbi request reprint A randomized comparison of two anemia treatment regimens in Tanzanian children
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Am J Trop Med Hyg 71:428-33. 2004
    ..06). Compliance was satisfactory in only 39% (82 of 209) of the children in the first week of treatment. Extending the duration of therapy and improving compliance may have health benefits for anemic children in malaria-endemic settings...
  19. ncbi request reprint Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple Plasmodium falciparum infections
    Francisco Saute
    Centro de Investigação em Saúde da Manhiça, Instituto Nacional de Saude, Maputo, Mozambique
    Trop Med Int Health 7:19-28. 2002
    ..It also tried to assess the frequency and effect on anaemia of submicroscopic and multiple falciparum infections...
  20. doi request reprint Treatment and prevention of malaria in pregnancy and newborn
    Oriol Coll
    Department of Maternal Fetal Medicine, Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic de Barcelona, Barcelona, Spain
    J Perinat Med 36:15-29. 2008
    ..In this paper, we review the pathology, diagnosis, and current recommendations for treatment and prevention of malaria in the pregnant woman and her infant...
  21. pmc Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications
    Clara Menendez
    Barcelona Center for International Health Research CRESIB, Hospital Clinic, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    Malar J 6:132. 2007
    ..Understanding the reasons for the discrepant results will help to elucidate the action mechanism of this intervention, which is essential for rational policy formulation...
  22. ncbi request reprint Antimalarial drugs in pregnancy: a review
    Francois Nosten
    Shoklo Malaria Research Unit, 63110 Mae Sot, Thailand
    Curr Drug Saf 1:1-15. 2006
    ..For these reasons there is an urgent need to assess the safety and efficacy of antimalarial treatments in pregnancy, including artemisinin based combination therapies...
  23. ncbi request reprint Seasonal variations in maternal mortality in Maputo, Mozambique: the role of malaria
    Cleofe Romagosa
    Department of Pathology, Hospital Clinic, University of Barcelona Institut d Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    Trop Med Int Health 12:62-7. 2007
    ..To evaluate the impact of malaria on maternal death through the analysis of the seasonal variations of crude and malaria-specific maternal mortality rates...
  24. ncbi request reprint Community response to intermittent preventive treatment delivered to infants (IPTi) through the EPI system in Manhiça, Mozambique
    Robert Pool
    London School of Hygiene and Tropical Medicine, London, UK, and Center for International Health, Hospital Clinic, IDIBAPS, Barcelona, Spain
    Trop Med Int Health 11:1670-8. 2006
    ..In particular, whether the introduction of IPTi negatively affects community attitudes to, or use of, EPI; or, conversely, whether and if so how, the concurrent delivery of IPTi and immunization influences perceptions of IPTi...
  25. ncbi request reprint Treatment and prevention of malaria in pregnancy: opportunities and challenges
    Stephen J Rogerson
    University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Australia
    Expert Rev Anti Infect Ther 4:687-702. 2006
    ..Prevention of pregnancy malaria by vaccination may also become possible, but targets must be closely defined, and strategies developed to test candidates against meaningful end points...
  26. ncbi request reprint Intermittent preventive treatment for malaria control administered at the time of routine vaccinations in Mozambican infants: a randomized, placebo-controlled trial
    Eusebio Macete
    Manhiça Health Research Center, Manhiça, Mozambique
    J Infect Dis 194:276-85. 2006
    ..There is an urgent need to deploy and develop new control tools that will reduce the intolerable burden of malaria. Intermittent preventive treatment in infants (IPTi) has the potential to become an effective tool for malaria control...
  27. ncbi request reprint The IPTi Consortium: research for policy and action
    David Schellenberg
    Department of Infectious Diseases, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK
    Trends Parasitol 22:296-300. 2006
    ..This review summarizes the available information on IPTi and presents the consortium's approach to determining whether IPTi might be a valuable additional strategy in programs to control malaria...
  28. ncbi request reprint Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial
    Pedro L Alonso
    Centre de Salut Internacional, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Lancet 366:2012-8. 2005
    ..An important remaining issue is the durability of protection against clinical disease in these children...
  29. ncbi request reprint Risk factors for presentation to hospital with severe anaemia in Tanzanian children: a case-control study
    Elizeus Kahigwa
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Trop Med Int Health 7:823-30. 2002
    ..The concentration of anaemia in infants and problems of access to health services and adequate case management underline the need for targeted preventive strategies for anaemia control...
  30. ncbi request reprint The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine, and their combination in the treatment of uncomplicated Plasmodium falciparum malaria
    David Schellenberg
    Unidad de Epidemiologia, Hospital Clinic, Barcelona, Spain
    Am J Trop Med Hyg 67:17-23. 2002
    ..6% vs. SP 29.9%; P = 0.001). The level of R1 resistance to SP may herald a rapid decline in its efficacy as SP drug pressure increases. Coadministration of AQ+SP may delay this...
  31. ncbi request reprint Polarisation microscopy increases the sensitivity of hemozoin and Plasmodium detection in the histological assessment of placental malaria
    Cleofe Romagosa
    Department of Anatomical Pathology, Facultat de Medicina, Institut d Investigacions Biomèdiques August Pi i Sunyer Hospital Clínic, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Acta Trop 90:277-84. 2004
    ..This method can be useful to investigators working in the malaria field...
  32. ncbi request reprint Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Lancet 365:1481-3. 2005
    ....