F Lozano

Summary

Affiliation: University of Barcelona
Country: Spain

Publications

  1. ncbi Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:216-20. 2001
  2. ncbi Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    J Immunol 166:396-402. 2001
  3. ncbi Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Immunol 31:1191-8. 2001
  4. ncbi Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial de Barcelona, Spain
    Cell Immunol 147:247-55. 1993
  5. ncbi Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase
    M Simarro
    Servei d'Immunologia, , , Barcelona, Spain
    J Immunol 162:5149-55. 1999
  6. ncbi Influence of mannose-binding lectin gene polymorphisms on the invasiveness of cytomegalovirus disease after solid organ transplantation
    C Cervera
    Infectious Diseases Service, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Transplant Proc 41:2259-61. 2009
  7. ncbi Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome
    M Ramos-Casals
    Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Rheumatology (Oxford) 48:65-9. 2009
  8. ncbi Identification of a new HLA-DRB1 allele (DRB1*0318) in three members of a Caucasian Spanish family
    M G Ercilla
    Institut Clínic d Infeccions i Immunologia ICII, Institut d Investigacions August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:489-91. 2001
  9. ncbi HLA-B*5130, a new HLA-B allele carrying a rare nucleotide substitution in exon 4
    I Gimferrer
    , , , Barcelona, Spain
    Tissue Antigens 61:97-8. 2003
  10. ncbi Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children
    X Valles
    International Research Center in Health of Barcelona CRESIB, Hospital Clínic de Barcelona IDIBAPS, Barcelona, Spain
    Tissue Antigens 74:298-307. 2009

Collaborators

Detail Information

Publications20

  1. ncbi Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:216-20. 2001
    ..Homo- or heterozygous combinations of these eight alleles accounted for all the IL4RA exon 11 genotypes found in Caucasian individuals from our geographical area...
  2. ncbi Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    J Immunol 166:396-402. 2001
    ..These results strongly argue in favor of a role for T410 and T412 in the signaling mediated by CD5...
  3. ncbi Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Immunol 31:1191-8. 2001
    ..We propose that T cell activation mediates CD5 tyrosine phosphorylation at residues Y429 and Y463 mainly through the activation of Lck...
  4. ncbi Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial de Barcelona, Spain
    Cell Immunol 147:247-55. 1993
    ..Our results indicate that the mAb-induced modulation of CD2 and CD5 is dependent on microfilament (namely actin) polymerization and PKC activation, while the modulation of CD3 is not...
  5. ncbi Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase
    M Simarro
    Servei d'Immunologia, , , Barcelona, Spain
    J Immunol 162:5149-55. 1999
    ..A-SMase, PKC-zeta, and MAPK family members are key mediators of cell responses as diverse as proliferation, differentiation, and growth arrest and may contribute to CD5-mediated modulation of TCR or BCR signaling...
  6. ncbi Influence of mannose-binding lectin gene polymorphisms on the invasiveness of cytomegalovirus disease after solid organ transplantation
    C Cervera
    Infectious Diseases Service, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Transplant Proc 41:2259-61. 2009
    ..Our aim was to evaluate the influence of MBL2 polymorphisms in the invasiveness of Cytomegalovirus (CMV) disease after solid organ transplantation...
  7. ncbi Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome
    M Ramos-Casals
    Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Rheumatology (Oxford) 48:65-9. 2009
    ..To investigate the association of mannose-binding lectin (MBL)-low genotypes with the clinical and immunological expression of primary SS...
  8. ncbi Identification of a new HLA-DRB1 allele (DRB1*0318) in three members of a Caucasian Spanish family
    M G Ercilla
    Institut Clínic d Infeccions i Immunologia ICII, Institut d Investigacions August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:489-91. 2001
    ....
  9. ncbi HLA-B*5130, a new HLA-B allele carrying a rare nucleotide substitution in exon 4
    I Gimferrer
    , , , Barcelona, Spain
    Tissue Antigens 61:97-8. 2003
    ..Although the frequency of the new variant seems to be low, its existence makes mandatory the analysis of exon 4 before assigning a B*5101 type...
  10. ncbi Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children
    X Valles
    International Research Center in Health of Barcelona CRESIB, Hospital Clínic de Barcelona IDIBAPS, Barcelona, Spain
    Tissue Antigens 74:298-307. 2009
    ..7%) and P111L (25.4%)] were compared with those of two previously reported variants (R103C and D105G). None of the analysed MASP2 variants, with the exception of D105G, interfered with interactions with either MBL or ficolins (H and L)...
  11. ncbi Intracellular events involved in CD5-induced human T cell activation and proliferation
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial, Barcelona, Spain
    J Immunol 148:1287-93. 1992
    ....
  12. ncbi Characterization of a new HLA-C allele: Cw*1606
    V Mas
    Servei d'Immunologia, , , , Barcelona, Spain
    Tissue Antigens 62:328-9. 2003
    ..Sequence comparisons suggest that the new HLA-Cw*1606 variant could have arisen from an intralocus gene conversion event...
  13. ncbi High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome
    M Ramos-Casals
    Systemic Autoimmune Diseases Unit and. Department of Immunology, , Department of Medicine, , School of Medicine, University of Barcelona, Barcelona, Spain
    Rheumatology (Oxford) 40:1056-9. 2001
    ..These facts may reflect an enhanced lymphocytic activation in patients with primary SS...
  14. ncbi Identification of a novel HLA-Cw*07 variant (Cw*0714) in a German Caucasian family
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 55:86-8. 2000
    ..The latest substitution (T-->C at the third position of codon 99) was not seen in any of the HLA-Cw*07 alleles reported so far, thus being characteristic to the new HLA-Cw*0714 allele...
  15. ncbi Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis
    J D Canete
    Rheumatology, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, School of Medicine, University of Barcelona, Barcelona, Spain
    Ann Rheum Dis 68:1547-52. 2009
    ....
  16. ncbi Novel MASP2 variants detected among North African and Sub-Saharan individuals
    F Lozano
    Servei d Immunologia, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Tissue Antigens 66:131-5. 2005
    ..5%). As reported for MBL2, the marked geographic distribution of the new MASP2 variants may represent an evolutionary adaptation to different environments...
  17. ncbi Association of mannose-binding lectin gene polymorphisms with antiphospholipid syndrome, cardiovascular disease and chronic damage in patients with systemic lupus erythematosus
    J Font
    Department of Autoimmune Diseases, Hospital Clinic, C Villarroel, 170 08036 Barcelona, Spain
    Rheumatology (Oxford) 46:76-80. 2007
    ..To investigate the association of mannose-binding lectin (MBL)-deficient genotypes with cardiovascular disease in a large series of patients with systemic lupus erythematosus (SLE)...
  18. ncbi Conformation of the hypervariable region L3 without the key proline residue
    A Guarné
    Department d Enginyeria Quimica, ETSEIB, UPC, Barcelona, Spain
    Protein Sci 5:167-9. 1996
    ..The conformation found could be significant for about 10% of the murine IgG molecules with kappa light chains without proline in their CDR-L3 sequences...
  19. ncbi Human CD5 signaling and constitutive phosphorylation of C-terminal serine residues by casein kinase II
    J Calvo
    Servei d Immunologia, Institut d Investigacions Biomédiques August Pii Sunger, Hospital Clinic, Barcelona, Spain
    J Immunol 161:6022-9. 1998
    ....
  20. ncbi Interleukin-4 receptor alpha polymorphisms in primary Sjögren's syndrome
    M Ramos-Casals
    Clin Exp Rheumatol 22:374. 2004