F Lozano

Summary

Affiliation: University of Barcelona
Country: Spain

Publications

  1. ncbi request reprint Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:216-20. 2001
  2. ncbi request reprint Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    J Immunol 166:396-402. 2001
  3. ncbi request reprint Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Immunol 31:1191-8. 2001
  4. ncbi request reprint Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial de Barcelona, Spain
    Cell Immunol 147:247-55. 1993
  5. ncbi request reprint Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase
    M Simarro
    Servei d'Immunologia, , , Barcelona, Spain
    J Immunol 162:5149-55. 1999
  6. doi request reprint Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children
    X Valles
    International Research Center in Health of Barcelona CRESIB, Hospital Clínic de Barcelona IDIBAPS, Barcelona, Spain
    Tissue Antigens 74:298-307. 2009
  7. doi request reprint Influence of mannose-binding lectin gene polymorphisms on the invasiveness of cytomegalovirus disease after solid organ transplantation
    C Cervera
    Infectious Diseases Service, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Transplant Proc 41:2259-61. 2009
  8. doi request reprint Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome
    M Ramos-Casals
    Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Rheumatology (Oxford) 48:65-9. 2009
  9. ncbi request reprint Identification of a new HLA-DRB1 allele (DRB1*0318) in three members of a Caucasian Spanish family
    M G Ercilla
    Institut Clínic d Infeccions i Immunologia ICII, Institut d Investigacions August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:489-91. 2001
  10. ncbi request reprint High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome
    M Ramos-Casals
    Systemic Autoimmune Diseases Unit and. Department of Immunology, , Department of Medicine, , School of Medicine, University of Barcelona, Barcelona, Spain
    Rheumatology (Oxford) 40:1056-9. 2001

Collaborators

  • A Roca
  • J Font
  • N M Thielens
  • F Cofan
  • Asunción Moreno Camacho
  • X Valles
  • K S Campbell
  • J Maertzdorf
  • J P Horcajada
  • D Tassies
  • A Moreno
  • R Cervera
  • J Vives
  • M Ramos-Casals
  • B Suarez
  • J Calvo
  • O Padilla
  • L Places
  • I Gimferrer
  • M Simarro
  • J M Vila
  • V Fabregat
  • C Cervera
  • J D Canete
  • M T Arias
  • P Brito-Zeron
  • M R Sarrias
  • V Mas
  • J Martorell
  • M G Ercilla
  • M Arman
  • J Alberola-Ila
  • C Moll
  • M Navasa
  • M Pascal
  • N Soria
  • R Sanmarti
  • R Celis
  • M A Marcos
  • G Sanclemente
  • I Rego
  • S Munoz
  • A Anton
  • C Aussel
  • J A Pinto
  • A Vargas
  • L Linares
  • D Balderramo
  • A Bove
  • M J Ricart
  • N Nardi
  • M V Hernandez
  • F J Blanco
  • E Roig
  • T Pumarola
  • M Garcia-Carrasco
  • Y Monreal
  • J Abian
  • O Trejo
  • J Yelamos
  • M Carrascal
  • E Palou
  • A Guarné
  • M A Bowen
  • A Guardia
  • M Costa
  • I Salinas
  • M Ingelmo
  • D Andreu
  • J M Vildà
  • C Lazaro
  • I Fita
  • J Bravo
  • D A Cantrell

Detail Information

Publications22

  1. ncbi request reprint Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:216-20. 2001
    ..Homo- or heterozygous combinations of these eight alleles accounted for all the IL4RA exon 11 genotypes found in Caucasian individuals from our geographical area...
  2. ncbi request reprint Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    J Immunol 166:396-402. 2001
    ..These results strongly argue in favor of a role for T410 and T412 in the signaling mediated by CD5...
  3. ncbi request reprint Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases
    J M Vila
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Immunol 31:1191-8. 2001
    ..We propose that T cell activation mediates CD5 tyrosine phosphorylation at residues Y429 and Y463 mainly through the activation of Lck...
  4. ncbi request reprint Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial de Barcelona, Spain
    Cell Immunol 147:247-55. 1993
    ..Our results indicate that the mAb-induced modulation of CD2 and CD5 is dependent on microfilament (namely actin) polymerization and PKC activation, while the modulation of CD3 is not...
  5. ncbi request reprint Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase
    M Simarro
    Servei d'Immunologia, , , Barcelona, Spain
    J Immunol 162:5149-55. 1999
    ..A-SMase, PKC-zeta, and MAPK family members are key mediators of cell responses as diverse as proliferation, differentiation, and growth arrest and may contribute to CD5-mediated modulation of TCR or BCR signaling...
  6. doi request reprint Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children
    X Valles
    International Research Center in Health of Barcelona CRESIB, Hospital Clínic de Barcelona IDIBAPS, Barcelona, Spain
    Tissue Antigens 74:298-307. 2009
    ..7%) and P111L (25.4%)] were compared with those of two previously reported variants (R103C and D105G). None of the analysed MASP2 variants, with the exception of D105G, interfered with interactions with either MBL or ficolins (H and L)...
  7. doi request reprint Influence of mannose-binding lectin gene polymorphisms on the invasiveness of cytomegalovirus disease after solid organ transplantation
    C Cervera
    Infectious Diseases Service, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Transplant Proc 41:2259-61. 2009
    ..Our aim was to evaluate the influence of MBL2 polymorphisms in the invasiveness of Cytomegalovirus (CMV) disease after solid organ transplantation...
  8. doi request reprint Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome
    M Ramos-Casals
    Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Rheumatology (Oxford) 48:65-9. 2009
    ..To investigate the association of mannose-binding lectin (MBL)-low genotypes with the clinical and immunological expression of primary SS...
  9. ncbi request reprint Identification of a new HLA-DRB1 allele (DRB1*0318) in three members of a Caucasian Spanish family
    M G Ercilla
    Institut Clínic d Infeccions i Immunologia ICII, Institut d Investigacions August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 57:489-91. 2001
    ....
  10. ncbi request reprint High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome
    M Ramos-Casals
    Systemic Autoimmune Diseases Unit and. Department of Immunology, , Department of Medicine, , School of Medicine, University of Barcelona, Barcelona, Spain
    Rheumatology (Oxford) 40:1056-9. 2001
    ..These facts may reflect an enhanced lymphocytic activation in patients with primary SS...
  11. ncbi request reprint HLA-B*5130, a new HLA-B allele carrying a rare nucleotide substitution in exon 4
    I Gimferrer
    Institut Clinic d Infeccions i Immunologia, Institut d Investigacions Mèdiques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 61:97-8. 2003
    ..Although the frequency of the new variant seems to be low, its existence makes mandatory the analysis of exon 4 before assigning a B*5101 type...
  12. ncbi request reprint Intracellular events involved in CD5-induced human T cell activation and proliferation
    J Alberola-Ila
    Servei d Immunologia, Hospital Clinic i Provincial, Barcelona, Spain
    J Immunol 148:1287-93. 1992
    ....
  13. ncbi request reprint Characterization of a new HLA-C allele: Cw*1606
    V Mas
    Servei d Immunologia, Institut Clínic d Infeccions i Immunologia ICII, Institut d Investigacions Mèdiques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 62:328-9. 2003
    ..Sequence comparisons suggest that the new HLA-Cw*1606 variant could have arisen from an intralocus gene conversion event...
  14. ncbi request reprint Human CD5 signaling and constitutive phosphorylation of C-terminal serine residues by casein kinase II
    J Calvo
    Servei d Immunologia, Institut d Investigacions Biomédiques August Pii Sunger, Hospital Clinic, Barcelona, Spain
    J Immunol 161:6022-9. 1998
    ....
  15. ncbi request reprint Identification of a novel HLA-Cw*07 variant (Cw*0714) in a German Caucasian family
    F Lozano
    Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Tissue Antigens 55:86-8. 2000
    ..The latest substitution (T-->C at the third position of codon 99) was not seen in any of the HLA-Cw*07 alleles reported so far, thus being characteristic to the new HLA-Cw*0714 allele...
  16. ncbi request reprint Biochemical characterization of recombinant and circulating human Spalpha
    M R Sarrias
    Servei d Immunologia, Institut Clinic d Infeccions i Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Villaroel 170, 08036 Barcelona, Spain
    Tissue Antigens 63:335-44. 2004
    ..Accordingly, rSpalpha allowed affinity chromatography isolation of polyclonal and monoclonal immunoglobulin M (IgM). These data indicate that Spalpha is a circulating protein that may play a role in the homeostasis of IgM antibodies...
  17. ncbi request reprint Association of mannose-binding lectin gene polymorphisms with antiphospholipid syndrome, cardiovascular disease and chronic damage in patients with systemic lupus erythematosus
    J Font
    Department of Autoimmune Diseases, Hospital Clinic, C Villarroel, 170 08036 Barcelona, Spain
    Rheumatology (Oxford) 46:76-80. 2007
    ..To investigate the association of mannose-binding lectin (MBL)-deficient genotypes with cardiovascular disease in a large series of patients with systemic lupus erythematosus (SLE)...
  18. doi request reprint Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis
    J D Canete
    Rheumatology, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, School of Medicine, University of Barcelona, Barcelona, Spain
    Ann Rheum Dis 68:1547-52. 2009
    ....
  19. ncbi request reprint Novel MASP2 variants detected among North African and Sub-Saharan individuals
    F Lozano
    Servei d Immunologia, Hospital Clinic de Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Tissue Antigens 66:131-5. 2005
    ..5%). As reported for MBL2, the marked geographic distribution of the new MASP2 variants may represent an evolutionary adaptation to different environments...
  20. pmc Conformation of the hypervariable region L3 without the key proline residue
    A Guarné
    Department d Enginyeria Quimica, ETSEIB, UPC, Barcelona, Spain
    Protein Sci 5:167-9. 1996
    ..The conformation found could be significant for about 10% of the murine IgG molecules with kappa light chains without proline in their CDR-L3 sequences...
  21. ncbi request reprint Conservation of a polymorphic microsatellite at orthologous positions in the human and mouse CD5 gene promoter
    J Calvo
    Servei d Immunologia, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Immunogenetics 45:233-4. 1997
  22. ncbi request reprint Interleukin-4 receptor alpha polymorphisms in primary Sjögren's syndrome
    M Ramos-Casals
    Clin Exp Rheumatol 22:374. 2004