Affiliation: University of Valencia
TardÃo J, Machado I, Navarro L, Idrovo F, Sanz Ortega J, PellÃn A, et al
. Ewing-like sarcoma with CIC-DUX4 gene fusion in a patient with neurofibromatosis type 1. A hitherto unreported association. Pathol Res Pract. 2015;211:877-82 pubmed publisher
Llombart Bosch A, Navarro S. Immunohistochemical detection of EWS and FLI-1 proteinss in Ewing sarcoma and primitive neuroectodermal tumors: comparative analysis with CD99 (MIC-2) expression. Appl Immunohistochem Mol Morphol. 2001;9:255-60 pubmed
..Whereas EWS expression does not appear specific for ES/PNET, analysis of FLI-1 expression together with CD-99 is a powerful marker for ES/PNET and important factors in the differential diagnosis of SRCT...
Llombart Bosch A, Machado I, Navarro S, Bertoni F, Bacchini P, Alberghini M, et al
. Histological heterogeneity of Ewing's sarcoma/PNET: an immunohistochemical analysis of 415 genetically confirmed cases with clinical support. Virchows Arch. 2009;455:397-411 pubmed publisher
..In conclusion, the diagnosis of atypical ES is a challenge for the pathologist and needs support from molecular techniques to perform an optimal differential diagnosis with other small round cell tumors. ..
Giner F, Lopez Guerrero J, Machado I, Garcia Casado Z, Fernandez Serra A, Peydró Olaya A, et al
. Expression profiles of angiogenesis in two high grade chondrosarcomas: A xenotransplant experience in nude mice. Histol Histopathol. 2017;32:1281-1291 pubmed publisher
..The present model may be useful for testing the effect of anti-angiogenic drugs. ..
van Oosterwijk J, de Jong D, van Ruler M, Hogendoorn P, Dijkstra P, van Rijswijk C, et al
. Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone. BMC Cancer. 2012;12:375 pubmed publisher
..In pre-clinical research aiming at the identification of novel treatment targets, the need for representative cell lines and model systems is high, but availability is scarce...