Research Topics
Genomes and GenesSpecies | Marta GarauletSummaryAffiliation: University of Murcia Country: Spain Publications
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Detail Information
Publications
[Comparative study of the type of obesity in pre- and postmenopausal women: Relationship with fat cell data, fatty acid composition and endocrine, metabolic, nutritional and psychological variables]Marta Garaulet
Departamento de Fisiologia, Universidad de Murcia, Spain
Med Clin (Barc) 118:281-6. 2002..The object of this study was to determine the type of obesity in a group of women along with its distinctive features, if any, as a function of the menopause stage...
Effectiveness of cognitive-behavioral therapy based on the Mediterranean diet for the treatment of obesityM Dolores Corbalán
Department of Physiology, University of Murcia, Spain
Nutrition 25:861-9. 2009..The objective of this study was to assess the effectiveness of behavioral therapy based on the Mediterranean diet for the treatment of obesity and to determine the main obstacles to weight loss...
Validation of a questionnaire on emotional eating for use in cases of obesity: the Emotional Eater Questionnaire (EEQ)M Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
Nutr Hosp 27:645-51. 2012..This relationship should be measurable to better understand how food is used to deal with certain mood states and how these emotions affect the effectiveness of weight loss programs...
Chronobiological aspects of nutrition, metabolic syndrome and obesityMarta Garaulet
Department of Physiology, University of Murcia, Spain
Adv Drug Deliv Rev 62:967-78. 2010..The main gaps in chronobiological research related to obesity will be also identified and chronobiological-based therapies will be proposed in order to allow the resetting of the circadian rhythm among obese subjects...
The chronobiology, etiology and pathophysiology of obesityM Garaulet
Faculty of Biology, Department of Physiology, Campus of Espinardo, University of Murcia, Murcia, Spain
Int J Obes (Lond) 34:1667-83. 2010..Such knowledge has the potential to become a valuable tool in the understanding of the relationship between the chronobiology, etiology and pathophysiology of obesity...
Relation between degree of obesity and site-specific adipose tissue fatty acid composition in a Mediterranean populationMarta Garaulet
Department of Physiology, University of Murcia, Campus de Espinardo, Murcia, Spain
Nutrition 27:170-6. 2011..The objective of the present study was to analyze potential differences in AT FA composition attending to degree of obesity in patients who follow a Mediterranean dietary pattern...
Behavioural therapy in the treatment of obesity (I): new directions for clinical practiceM Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
Nutr Hosp 24:629-39. 2009..Besides, new approaches have been developed which contribute to increase the success of the treatments, like non face-to-face techniques, or the new cognitive therapy...
PERIOD2 variants are associated with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treatment of obesityMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Campus de Espinardo, s n 30100, Murcia, Spain
J Am Diet Assoc 110:917-21. 2010..These findings could represent a step toward personalized health care and nutrition based on a combination of genotyping and psycho-behavioral characterization...
Anthropometric indexes for visceral fat estimation in overweight/obese women attending to age and menopausal statusM Garaulet
Department of Physiology, University of Murcia, Campus de Espinardo, 30100 Murcia, Spain
J Physiol Biochem 62:245-52. 2006..In contrast with previous findings, waist circumferences do not seem to be useful for predicting VA...
Behavioural therapy in the treatment of obesity (II): role of the Mediterranean dietMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Campus de Espinardo, Murcia, Spain
Nutr Hosp 25:9-17. 2010..This revision discusses the role of diet in the behavioural treatment (BT) of obesity, which faces multiple approaches and focuses on patients' behaviour rather than their mere energy intake...
Adiponectin, the controversial hormoneMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Campus de Espinardo, s n 30100, Murcia, Spain
Public Health Nutr 10:1145-50. 2007..There are important confounding results regarding the mechanisms of action and functions of adiponectin, especially in relation to insulin resistance and inflammation...
CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean dietM Garaulet
Department of Physiology, University of Murcia, Murcia, Spain
Int J Obes (Lond) 34:516-23. 2010..Circadian Locomotor Output Cycles Kaput (CLOCK), one of the transcription factors from the positive limb of the molecular clock, is involved in metabolic alterations...
Two-dimensional predictive equation to classify visceral obesity in clinical practiceMarta Garaulet
Department of Physiology, University of Murcia, 30100 Murcia, Spain
Obesity (Silver Spring) 14:1181-91. 2006..We developed a new two-dimensional elliptical anthropometric equation to classify visceral obesity and evaluated the validity and the reliability of the new equation compared with CT...
Relationship between fat cell size and number and fatty acid composition in adipose tissue from different fat depots in overweight/obese humansM Garaulet
Department of Physiology, University of Murcia, Murcia, Spain
Int J Obes (Lond) 30:899-905. 2006....
Adiposity and dietary intake in cardiovascular risk in an obese population from a Mediterranean areaM Garaulet
Dept of Physiology, Univ of Murcia, Campus de Espinardo, Virgen de la Arrixaca University Hospital, Murcia, Spain
J Physiol Biochem 60:39-49. 2004....
Chronobiology, genetics and metabolic syndromeMarta Garaulet
Department of Physiology, University of Murcia, Murcia, Spain
Curr Opin Lipidol 20:127-34. 2009..This review summarizes the latest evidence of the existing interaction among chronobiology, genetics and MetS...
PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioural treatment based on the Mediterranean dietMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
Mol Nutr Food Res 55:1771-9. 2011....
CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acidsMarta Garaulet
Department of Physiology, University of Murcia, Murcia, Spain
Am J Clin Nutr 90:1466-75. 2009..Disruption of the circadian system may be causal for manifestations of the metabolic syndrome (MetS)...
Interrelationship between serum lipid profile, serum hormones and other components of the metabolic syndromeM Garaulet
Departmento de Fisiologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
J Physiol Biochem 58:151-60. 2002....
Short sleep duration is associated with increased obesity markers in European adolescents: effect of physical activity and dietary habits. The HELENA studyM Garaulet
Department of Physiology, University of Murcia, Campus de Espinardo s n, Murcia, Spain
Int J Obes (Lond) 35:1308-17. 2011..Adequate sleep is a critical factor for adolescent's health and health-related behaviors...
An approximation to the temporal order in endogenous circadian rhythms of genes implicated in human adipose tissue metabolismMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
J Cell Physiol 226:2075-80. 2011..For every gene, protein mRNA levels fluctuated during the day in synchrony with its receptors. We have provided an overall view of the internal temporal order of circadian rhythms in human adipose tissue...
Ghrelin, sleep reduction and evening preference: relationships to CLOCK 3111 T/C SNP and weight lossMarta Garaulet
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
PLoS ONE 6:e17435. 2011....
Genetic variants in human CLOCK associate with total energy intake and cytokine sleep factors in overweight subjects (GOLDN population)Marta Garaulet
Department of Physiology, University of Murcia, Murcia, Spain
Eur J Hum Genet 18:364-9. 2010..Associations could be mediated through the alteration of cytokine levels that may influence energy intake and sleep pattern...
Age-related changes in fatty acids from different adipose depots in rat and their association with adiposity and insulinFátima Pérez de Heredia
Department of Physiology, University of Murcia, Murcia, Spain
Nutrition 24:1013-22. 2008..We studied age-related changes in fatty acids (FAs) from serum and adipose tissue in rats by comparing different adipose regions and analyzed their relations to adiposity and insulin function...
Adiponectin is involved in the protective effect of DHEA against metabolic risk in aged ratsFátima Pérez-de-Heredia
Department of Physiology, University of Murcia, Paseo Rector Sabater s n, Campus de Espinardo, 30100 Murcia, Spain
Steroids 73:1128-36. 2008..Our results then suggest that adiponectin is involved in the protective effect of DHEA against metabolic risk demonstrated in the present work...
Circadian rhythm of clock genes in human adipose explantsCecilia Gómez-Santos
Department of Physiology, University of Murcia, Murcia, Spain
Obesity (Silver Spring) 17:1481-5. 2009..This knowledge paves the way for a better understanding of the circadian contribution to medical conditions such as obesity and MetS...
N-6 from different sources protect from metabolic alterations to obese patients: a factor analysisJuan J Hernández-Morante
Department of Physiology, University of Murcia, Murcia, Spain
Obesity (Silver Spring) 17:452-9. 2009..These findings support current dietary recommendations to increase PUFA intakes and restrict saturated and trans FA intakes even in extreme obesity...
[Chronobiological aspects of obesity and metabolic syndrome]Purificación Gómez-Abellán
Departamento de Fisiologia, Facultad de Biologia, Universidad de Murcia, Murcia, Espana
Endocrinol Nutr 59:50-61. 2012..Finally, ideas about use of chronobiology for the treatment of obesity are discussed...
APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean populationCarmen Sánchez-Moreno
Department of Physiology, University of Murcia, Campus de Espinardo, s n 30100, Murcia, Spain
J Nutr 141:380-5. 2011..Our data support the hypothesis that the minor C-allele may protect those consuming a high-fat diet from obesity and elevated concentrations of TG-rich lipoproteins...
Effect of dehydroepiandrosterone on protein and fat digestibility, body protein and muscular composition in high-fat-diet-fed old ratsFátima Pérez de Heredia
Department of Physiology, University of Murcia, Murcia, Spain
Br J Nutr 97:464-70. 2007..The anti-obesity properties of DHEA could be related to a reduction in protein digestibility in the short term and a protective effect on body protein with a selective mass loss from body fat...
Differential effect of oral dehydroepiandrosterone-sulphate on metabolic syndrome features in pre- and postmenopausal obese womenCecilia Gómez-Santos
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
Clin Endocrinol (Oxf) 77:548-54. 2012..To analyze the effect in obese pre- and postmenopausal women of a daily dose of 100 mg dehydroepiandrosterone-sulphate (DHEA-S) provided over a period of 3 months as replacement therapy against metabolic syndrome...
Dehydroepiandrosterone-sulfate modifies human fatty acid composition of different adipose tissue depotsJuan Jose Hernandez-Morante
School of Nursery, Catholic University of Murcia, Campus de Guadalupe, Murcia, Spain
Obes Surg 21:102-11. 2011..Thus, we could hypothesize that some of the beneficial effects shown by DHEA-S in humans are related to a modification of the human AT-FA profile. The present study examines this question and whether this effect is tissue-dependent...
Role of DHEA-S on body fat distribution: gender- and depot-specific stimulation of adipose tissue lipolysisJuan J Hernández-Morante
Department of Physiology, University of Murcia, and Surgery Service, University Hospital Virgen de la Arrixaca, Spain
Steroids 73:209-15. 2008..We have demonstrated for the first time in vitro that DHEA-S stimulates lipolysis preferably in subcutaneous fat in women and in visceral fat in men...
Dehydroepiandrosterone modifies rat fatty acid composition of serum and different adipose tissue depots and lowers serum insulin levelsFátima Pérez de Heredia
Department of Physiology, University of Murcia, Murcia, Spain
J Endocrinol 201:67-74. 2009..We propose that these changes may be related to the capacity of DHEA to lower serum insulin levels...
Resistance to dietary obesity in rats given different high-energy dietsFátima Pérez de Heredia
Department of Physiology, University of Murcia, Murcia, 30100, Spain
Int J Vitam Nutr Res 76:271-9. 2006..In view of the strong resistance to obesity observed in rats, it should be important for researchers to transmit the difficulties of inducing dietary obesity in these animals, in order to prevent bias in science interpretation...
New computed tomography-derived indices to predict cardiovascular and insulin-resistance risks in overweight/obese patientsC Piernas
Department of Physiology, University of Murcia, Campus de Espinardo, Murcia 30100, Spain
Eur J Clin Nutr 63:887-97. 2009..A second objective is to propose specific or sensitive threshold values of the most accurate criteria for the occurrence of metabolic disturbances...
Influence of menopause on adipose tissue clock gene genotype and its relationship with metabolic syndrome in morbidly obese womenJuan Jose Hernandez-Morante
Department of Physiology, University of Murcia, Murcia, Spain
Age (Dordr) 34:1369-80. 2012..We conclude that menopause transition induces several changes in the genotype of the adipose tissue chronobiological machinery related to an increased risk of developing MetS...
Profile of adipose tissue gene expression in premenopausal and postmenopausal women: site-specific differencesCecilia Gómez-Santos
Department of Physiology, University of Murcia, Murcia, Spain
Menopause 18:675-84. 2011..The objectives of the present study, therefore, were to analyze differences in adipose tissue gene expression between premenopausal and postmenopausal women and to ascertain whether any differences were depot specific...
Relationship among adiponectin, adiponectin gene expression and fatty acids composition in morbidly obese patientsJuan Jose Hernandez Morante
Department of Physiology, University of Murcia, Murcia, Spain
Obes Surg 17:516-24. 2007....
Body fat distribution in pre-and post-menopausal women: metabolic and anthropometric variablesM Garaulet
Dep Physiology, University of Murcia, Spain
J Nutr Health Aging 6:123-6. 2002..Metabolic abnormalities are related more to visceral adipose tissue and estrogen plasma levels than to BMI...
Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesityM Garaulet
Department of Physiology and Pharmacology, University of Murcia, Murcia, Spain
Am J Clin Nutr 74:585-91. 2001..05). CONCLUSION: The differences found in the composition and metabolism of perivisceral, omental, and subcutaneous fats may indicate that their atherogenic capacities also differ...
Endocrine, metabolic and nutritional factors in obesity and their relative significance as studied by factor analysisM Garaulet
Department of Physiology and Pharmacology, University of Murcia, Murcia, Spain
Int J Obes Relat Metab Disord 25:243-51. 2001..Secondary factors include endocrine and metabolic factors...
Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant culturesPurificación Gómez-Abellán
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
PLoS ONE 7:e50435. 2012....
Effect of DHEA-sulfate on adiponectin gene expression in adipose tissue from different fat depots in morbidly obese humansJuan Jose Hernandez-Morante
Department of Physiology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain
Eur J Endocrinol 155:593-600. 2006....
[Multivalent informatics application for studies of the nutritional status of the population. Assessment of food intake]F Perez-Llamas
Departamento de Fisiologia, Facultad de Biologia, Universidad de Murcia, Campus de Espinardo, 30100 Murcia
Nutr Hosp 19:160-6. 2004..However, once validated, this tool has the particularity of being developed after an important experience in the nutritional field and only with a scientific purpose. The result is a reliable tool, which facilitates nutrition research...
Influence of dietary protein type and iron source on the absorption of amino acids and mineralsF Perez-Llamas
Department of Physiology, Faculty of Biology, University of Murcia, Spain
J Physiol Biochem 57:321-8. 2001....
Effect of protein hydrolysis on the dialysability of amino acids and minerals in infant formulasF Perez-Llamas
Department of Physiology, University of Murcia, 30100 Murcia, Spain
J Physiol Biochem 59:19-24. 2003..Despite its limitations of having to be carried out in vitro, the study suggests that the nutritional value in relation with amino acids, minerals and trace elements differs between the both types of formulas...
Adiponectin is associated with serum and adipose tissue fatty acid composition in ratsF Perez de Heredia
Dept Physiology, University of Murcia, Paseo Rector Sabater s n, Campus de Espinardo, 30100 Murcia, Spain
J Endocrinol Invest 32:659-65. 2009..In addition, most associations were found in the visceral depots, highlighting the importance of visceral fat in the metabolic status...
Insulin effect on adipose tissue (AT) adiponectin expression is regulated by the insulin resistance status of the patientsJ J Hernandez-Morante
Department of Physiology, University of Murcia, Murcia, Spain
Clin Endocrinol (Oxf) 69:412-7. 2008..A secondary aim was to analyse the associations of adiponectin plasma levels, as well as control and insulin-stimulated gene expression levels with different features of the metabolic syndrome...
Cortisol secretary pattern and glucocorticoid feedback sensitivity in women from a Mediterranean area: relationship with anthropometric characteristics, dietary intake and plasma fatty acid profileM D García Prieto
Department of Physiology, University of Murcia, Murcia, Spain
Clin Endocrinol (Oxf) 66:185-91. 2007..Chronic stress is associated with a dysfunctional hypothalamic-pituitary-adrenal (HPA) axis consisting on disturbances on the cortisol response and lipid metabolism...
Circadian expression of adiponectin and its receptors in human adipose tissueP Gómez-Abellán
Department of Physiology, Faculty of Biology, University of Murcia, Campus de Espinardo, s n 30100 Murcia, Spain
Endocrinology 151:115-22. 2010..The mRNA expression of adiponectin and its receptors showed 24-h rhythmicity in human AT from morbidly obese patients...
Health-related physical fitness according to chronological and biological age in adolescents. The AVENA studyF B Ortega
Department of Physiology, School of Medicine, University of Granada, Granada, Spain
J Sports Med Phys Fitness 48:371-9. 2008..The aim of the present study was to determine the levels of several health-related physical fitness components with respect to chronological and biological age (sexual maturation status) in Spanish adolescents...
Clock genes are implicated in the human metabolic syndromeP Gómez-Abellán
Department of Physiology, University of Murcia, Murcia, Spain
Int J Obes (Lond) 32:121-8. 2008..Clock genes play a role in adipose tissue (AT) in animal experimental models. However, it remains to be elucidated whether these genes are expressed in human AT...
Expression of cortisol metabolism-related genes shows circadian rhythmic patterns in human adipose tissueJ J Hernandez-Morante
Department of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain
Int J Obes (Lond) 33:473-80. 2009..A second objective was to characterize the circadian rhythmicity of these genes in both adipose tissue (AT) regions...
Harmonization of anthropometric measurements for a multicenter nutrition survey in Spanish adolescentsLuis A Moreno
E U Ciencias de la Salud, Departamento de Pediatria, Universidad de Zaragoza, Aveñida Domingo Miral s n, 50009 Zaragoza, Spain
Nutrition 19:481-6. 2003..We describe the standardization process and reliability of anthropometric measurements carried out in a pilot study...
Adiponectin gene expression and plasma values in obese women during very-low-calorie diet. Relationship with cardiovascular risk factors and insulin resistanceMarta Garaulet
Franco Czech Laboratory for Clinical Research on Obesity, French Institute of Health and Medical Research, Institut National de la Santé et d la Recherche Médicale U586 and 3rd Faculty of Medicine, Charles University, Prague, Czech Republic
J Clin Endocrinol Metab 89:756-60. 2004..The data suggest that adiponectin is related to the protection against the metabolic syndrome but is not involved in the regulation of VLCD-induced improvement of insulin sensitivity...
