Affiliation: University of Navarra
Collantes M, Penuelas I, Alvarez Erviti L, Blesa J, Martí Climent J, Quincoces G, et al
. [Use of 11C-(+)-alpha -dihydrotetrabenazine for the assessment of dopaminergic innervation in animal models of Parkinson's disease]. Rev Esp Med Nucl. 2008;27:103-11 pubmed
..The quality of PET images and the decrease of uptake in 6-OHDA and MPTP lesions show that (11)C-(+)DTBZ is an adequate radiotracer for the study of dopaminergic innervation in these animal models. ..
Collantes M, Barajas M, Quincoces G, Ramos Membrive R, MartÃ Climent J, Ecay M, et al
. Lessons from 11C-dihydrotetrabenazine imaging in a xenograft mouse model of rat insulinoma: is PET imaging of pancreatic beta cell mass feasible?. Q J Nucl Med Mol Imaging. 2017;61:447-455 pubmed publisher
..This might either be due to inherent technical limitations of PET, decrease in VMAT2 expression in the tumors due to unknown reasons, or other biological limiting facts. ..
Martí Climent J, Collantes M, Jauregui Osoro M, Quincoces G, Prieto E, Bilbao I, et al
. Radiation dosimetry and biodistribution in non-human primates of the sodium/iodide PET ligand [(18)F]-tetrafluoroborate. EJNMMI Res. 2015;5:70 pubmed publisher
..It delivers an effective dose slightly higher than the dose produced by (99m)Tc-pertechnetate but much lower than that produced by radioiodine in the form of (131)INa, (123)INa, or (124)INa. ..
Diaz R, Nguewa P, Parrondo R, Perez Stable C, Manrique I, Redrado M, et al
. Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model. BMC Cancer. 2010;10:188 pubmed publisher
..In addition, tumors from lapatinib-treated mice showed a dramatic reduction in angiogenesis (P < 0.0001). Overall, these data suggest that lapatinib may be a clinically useful agent for the treatment of lung cancer. ..