Antonio Carvajal-Rodriguez

Summary

Affiliation: University of Vigo
Country: Spain

Publications

  1. doi request reprint Teaching the fluctuation test in silico by using mutate: a program to distinguish between the adaptive and spontaneous mutation hypotheses
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo 36310, Spain
    Biochem Mol Biol Educ 40:277-83. 2012
  2. pmc Evidence of recombination within human alpha-papillomavirus
    Manuel Angulo
    Department of Pathology, Complejo Hospitalario Universitario de Vigo, 36204 Vigo, Spain
    Virol J 4:33. 2007
  3. pmc Assessing significance in high-throughput experiments by sequential goodness of fit and q-value estimation
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    PLoS ONE 6:e24700. 2011
  4. pmc A new multitest correction (SGoF) that increases its statistical power when increasing the number of tests
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    BMC Bioinformatics 10:209. 2009
  5. ncbi request reprint The importance of bio-computational tools for predicting HIV drug resistance
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología Universidad de Vigo, 36310 Vigo, Spain
    Recent Pat DNA Gene Seq 1:63-8. 2007
  6. doi request reprint Detecting recombination and diversifying selection in human alpha-papillomavirus
    A Carvajal-Rodriguez
    Dpto de Bioquímica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Infect Genet Evol 8:689-92. 2008
  7. pmc GENOMEPOP: a program to simulate genomes in populations
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Universidad de Vigo, 36310 Vigo, Spain
    BMC Bioinformatics 9:223. 2008
  8. pmc Recombination favors the evolution of drug resistance in HIV-1 during antiretroviral therapy
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, 84602 Provo, UT, USA
    Infect Genet Evol 7:476-83. 2007
  9. pmc Recombination estimation under complex evolutionary models with the coalescent composite-likelihood method
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, USA
    Mol Biol Evol 23:817-27. 2006
  10. pmc JMATING: a software for the analysis of sexual selection and sexual isolation effects from mating frequency data
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah 84602, USA
    BMC Evol Biol 6:40. 2006

Collaborators

Detail Information

Publications14

  1. doi request reprint Teaching the fluctuation test in silico by using mutate: a program to distinguish between the adaptive and spontaneous mutation hypotheses
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo 36310, Spain
    Biochem Mol Biol Educ 40:277-83. 2012
    ..uvigo.es/acraaj/MutateWeb/Mutate.html. It requires the Java 5.0 (or higher) Runtime Environment (freely available at http://www.java.com)...
  2. pmc Evidence of recombination within human alpha-papillomavirus
    Manuel Angulo
    Department of Pathology, Complejo Hospitalario Universitario de Vigo, 36204 Vigo, Spain
    Virol J 4:33. 2007
    ..In addition, recombination could also be a significant issue nowadays since the frequency of co-infection with more than one HPV type is not a rare event and, thus, new recombinant types could be currently being generated...
  3. pmc Assessing significance in high-throughput experiments by sequential goodness of fit and q-value estimation
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    PLoS ONE 6:e24700. 2011
    ..These techniques are provided in the latest version of the SGoF+ software freely available at http://webs.uvigo.es/acraaj/SGoF.htm...
  4. pmc A new multitest correction (SGoF) that increases its statistical power when increasing the number of tests
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    BMC Bioinformatics 10:209. 2009
    ..The method is compared with Bonferroni and FDR-based alternatives by simulating a multitest context via two different kinds of tests: 1) one-sample t-test, and 2) homogeneity G-test...
  5. ncbi request reprint The importance of bio-computational tools for predicting HIV drug resistance
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología Universidad de Vigo, 36310 Vigo, Spain
    Recent Pat DNA Gene Seq 1:63-8. 2007
    ..Importantly, the revised patents conform to this trend...
  6. doi request reprint Detecting recombination and diversifying selection in human alpha-papillomavirus
    A Carvajal-Rodriguez
    Dpto de Bioquímica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Infect Genet Evol 8:689-92. 2008
    ..These results indicate that positive selection could have been important in the evolution of HPV both at inter- and intra-type levels...
  7. pmc GENOMEPOP: a program to simulate genomes in populations
    Antonio Carvajal-Rodriguez
    Departamento de Bioquimica, Genética e Inmunología, Universidad de Vigo, 36310 Vigo, Spain
    BMC Bioinformatics 9:223. 2008
    ..Here I will introduce GenomePop, a forward simulation program that fulfills the above requirements. The use of the program is demonstrated by studying the impact of intracodon recombination on global and site-specific dN/dS estimation...
  8. pmc Recombination favors the evolution of drug resistance in HIV-1 during antiretroviral therapy
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, 84602 Provo, UT, USA
    Infect Genet Evol 7:476-83. 2007
    ..Our results suggest that recombination plays an important role in the evolution of drug resistance in HIV-1 under various realistic scenarios. These findings could be taken into account in order to develop optimal HIV-1 drug treatments...
  9. pmc Recombination estimation under complex evolutionary models with the coalescent composite-likelihood method
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, USA
    Mol Biol Evol 23:817-27. 2006
    ..In such cases, the use of more complex models slightly increases performance in some occasions, especially in the case of the LPT. Thus, our results provide for a more robust application of the estimation of recombination rates...
  10. pmc JMATING: a software for the analysis of sexual selection and sexual isolation effects from mating frequency data
    Antonio Carvajal-Rodriguez
    Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah 84602, USA
    BMC Evol Biol 6:40. 2006
    ..However, there is no available software that implements all these statistical estimators and their corresponding tests for the study of mating behaviour...
  11. pmc 'SGoFicance Trace': assessing significance in high dimensional testing problems
    Jacobo de Uña-Álvarez
    Departamento de Estadística e Investigación Operativa, Facultad de Ciencias Económicas y Empresariales, Universidad de Vigo, Vigo, Spain
    PLoS ONE 5:e15930. 2010
    ..A script has been written for the computation in R of the SGoFicance Trace. This script is available from the web site http://webs.uvigo.es/acraaj/SGoFicance.htm...
  12. doi request reprint Disease progression and evolution of the HIV-1 env gene in 24 infected infants
    Antonio Carvajal-Rodriguez
    Department of Biology, Brigham Young University, 84602 Provo, UT, USA
    Infect Genet Evol 8:110-20. 2008
    ..Overall, the results obtained confirm that viral adaptation in the C2V3C3 region of the env gene is related to disease progression, although the statistical characterization of such pattern seems rather difficult...
  13. pmc Multiple hypothesis testing in proteomics: a strategy for experimental work
    Angel P Diz
    Department of Biochemistry, Genetics and Immunology, Faculty of Biology, University of Vigo, 36310, Vigo, Spain
    Mol Cell Proteomics 10:M110.004374. 2011
    ..This approach is demonstrated using case scenarios with experimental and simulated model data...
  14. ncbi request reprint Application of relative warp analysis to the evaluation of two-dimensional gels in proteomics: studying isoelectric point and relative molecular mass variation
    Ana M Rodríguez-Piñeiro
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Campus Universitario, 36310 Vigo, Spain
    J Proteome Res 4:1318-23. 2005
    ..Applying this approach, we detected variations in the position (isoelectric point and/or relative molecular mass) of some spots that may reflect differences in the amino acidic sequence or post-translational modifications...