A Caballero

Summary

Affiliation: University of Vigo
Country: Spain

Publications

  1. ncbi Inferences on genome-wide deleterious mutation rates in inbred populations of Drosophila and mice
    A Caballero
    Dep Bioquímica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Spain
    Genetica 102:229-39. 1998
  2. ncbi Estimation of the upper limit of the mutation rate and mean heterozygous effect of deleterious mutations
    A Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Genet Res 88:137-41. 2006
  3. ncbi Analysis of the biases in the estimation of deleterious mutation parameters from natural populations at mutation-selection balance
    A Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Genet Res 88:177-89. 2006
  4. ncbi Impact of amplified fragment length polymorphism size homoplasy on the estimation of population genetic diversity and the detection of selective loci
    Armando Caballero
    Departamento de Bioquimica, Genetica, e Inmunología, Facultad de Biologia, Universidade de Vigo, 36310 Vigo, Spain
    Genetics 179:539-54. 2008
  5. ncbi Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection
    A Caballero
    Departamento de Bioquimica, Xenética e Inmunoloxía, Facultade de Ciencias, Universidade de Vigo, Spain
    Evolution 56:1150-9. 2002
  6. ncbi Homoplasy and distribution of AFLP fragments: an analysis in silico of the genome of different species
    Armando Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidade de Vigo, Vigo, Spain
    Mol Biol Evol 27:1139-51. 2010
  7. ncbi Interrelations between effective population size and other pedigree tools for the management of conserved populations
    A Caballero
    Departamento de Bioquimica, Genética e Immunología, Facultad de Ciencias, Universidad de Vigo, Spain
    Genet Res 75:331-43. 2000
  8. ncbi Properties of spontaneous mutations affecting quantitative traits
    A Garcia-Dorado
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, Madrid, Spain
    Genet Res 74:341-50. 1999
  9. ncbi Mutation-selection balance accounting for genetic variation for viability in Drosophila melanogaster as deduced from an inbreeding and artificial selection experiment
    S T Rodríguez-Ramilo
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Spain
    J Evol Biol 17:528-41. 2004
  10. ncbi Analysis of the estimators of the average coefficient of dominance of deleterious mutations
    B Fernandez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain
    Genetics 168:1053-69. 2004

Collaborators

Detail Information

Publications33

  1. ncbi Inferences on genome-wide deleterious mutation rates in inbred populations of Drosophila and mice
    A Caballero
    Dep Bioquímica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Spain
    Genetica 102:229-39. 1998
    ..Recent estimates suggesting an overall mutation pressure for fitness traits of about 0.1% are, however, compatible with the observed load...
  2. ncbi Estimation of the upper limit of the mutation rate and mean heterozygous effect of deleterious mutations
    A Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Genet Res 88:137-41. 2006
    ..The assumption of lower mutation rates and/or other models of balancing selection may imply considerably larger biases of the estimates, making the reliability of the proposed method highly questionable...
  3. ncbi Analysis of the biases in the estimation of deleterious mutation parameters from natural populations at mutation-selection balance
    A Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Genet Res 88:177-89. 2006
    ..2, although the data are scarce and noisy, and should be used with caution...
  4. ncbi Impact of amplified fragment length polymorphism size homoplasy on the estimation of population genetic diversity and the detection of selective loci
    Armando Caballero
    Departamento de Bioquimica, Genetica, e Inmunología, Facultad de Biologia, Universidade de Vigo, 36310 Vigo, Spain
    Genetics 179:539-54. 2008
    ..Overall, the results indicate that the software should be used with caution. AFLP homoplasy can produce a reduction of up to 15% in the power to detect selective loci...
  5. ncbi Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection
    A Caballero
    Departamento de Bioquimica, Xenética e Inmunoloxía, Facultade de Ciencias, Universidade de Vigo, Spain
    Evolution 56:1150-9. 2002
    ..It also predicted a rate of line extinction too low in the early generations and too high in the later ones. In contrast, the model based on few mutations of large effect was generally consistent with all the observations...
  6. ncbi Homoplasy and distribution of AFLP fragments: an analysis in silico of the genome of different species
    Armando Caballero
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidade de Vigo, Vigo, Spain
    Mol Biol Evol 27:1139-51. 2010
    ..4) Nor is the disagreement eliminated by using restriction enzymes with balanced motifs. 5) The discrepancy seems to be caused, rather, by the nonrandom distribution of restriction enzyme motifs...
  7. ncbi Interrelations between effective population size and other pedigree tools for the management of conserved populations
    A Caballero
    Departamento de Bioquimica, Genética e Immunología, Facultad de Ciencias, Universidad de Vigo, Spain
    Genet Res 75:331-43. 2000
    ..The method of choice of parents and the system of mating should be independent of each other because a clear-cut recommendation cannot be given on the latter...
  8. ncbi Properties of spontaneous mutations affecting quantitative traits
    A Garcia-Dorado
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, Madrid, Spain
    Genet Res 74:341-50. 1999
    ..This should be close to that responsible for standing variation in natural populations...
  9. ncbi Mutation-selection balance accounting for genetic variation for viability in Drosophila melanogaster as deduced from an inbreeding and artificial selection experiment
    S T Rodríguez-Ramilo
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Spain
    J Evol Biol 17:528-41. 2004
    ....
  10. ncbi Analysis of the estimators of the average coefficient of dominance of deleterious mutations
    B Fernandez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain
    Genetics 168:1053-69. 2004
    ....
  11. ncbi Genetic differentiation and estimation of effective population size and migration rates in two sympatric ecotypes of the marine snail Littorina saxatilis
    J Fernandez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain
    J Hered 96:460-4. 2005
    ....
  12. ncbi AFLPMax: a user-friendly application for computing the optimal number of amplified fragment length polymorphism markers needed in phylogenetic reconstruction
    M J García-Pereira
    Departamento de Bioquimica, Genética e Inmunología, Universidad de Vigo, 36310 Vigo, Spain
    Mol Ecol Resour 12:566-9. 2012
    ..Executables for Windows, linux and MacOS X operating systems, source code and user manual are available from: http://webs.uvigo.es/acraaj/AFLPMax.htm...
  13. ncbi The effect of antagonistic pleiotropy on the estimation of the average coefficient of dominance of deleterious mutations
    B Fernandez
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, 28040 Madrid, Spain
    Genetics 171:2097-112. 2005
    ....
  14. ncbi The mutational rate of Drosophila viability decline: tinkering with old data
    A Garcia-Dorado
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, 28040 Madrid, Spain
    Genet Res 80:99-105. 2002
    ..011) or from the linear term in a quadratic unforced regression (delta MII = 0.001) are very different. The data fit both models very well, and the choice between them should be based on biological grounds...
  15. ncbi An experimental evaluation with Drosophila melanogaster of a novel dynamic system for the management of subdivided populations in conservation programs
    V Avila
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Pontevedra, Spain
    Heredity (Edinb) 106:765-74. 2011
    ....
  16. ncbi The evolutionary forces maintaining a wild polymorphism of Littorina saxatilis: model selection by computer simulations
    A Pérez-Figueroa
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Vigo, Spain
    J Evol Biol 18:191-202. 2005
    ....
  17. ncbi Estimating sexual selection and sexual isolation effects from mating frequencies
    E Rolan-Alvarez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, Spain
    Evolution 54:30-6. 2000
    ..The use of the classical indexes applied to PSI coefficients considerably reduces the statistical bias of the estimates, revealing the good estimation properties of the new statistics...
  18. ncbi Relaxation of selection with equalization of parental contributions in conservation programs: an experimental test with Drosophila melanogaster
    S T Rodríguez-Ramilo
    Departamento de Bioquimica, Genética e Inmunología, Universidad de Vigo, 36310 Vigo, Spain
    Genetics 172:1043-54. 2006
    ....
  19. ncbi Comparing three different methods to detect selective loci using dominant markers
    A Pérez-Figueroa
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    J Evol Biol 23:2267-76. 2010
    ..Our results show, nevertheless, that false positives are common even with a combination of methods and multitest correction, suggesting that conclusions obtained from this approach should be taken with extreme caution...
  20. ncbi Accumulation of deleterious mutations and equalization of parental contributions in the conservation of genetic resources
    J Fernandez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain
    Heredity 86:480-8. 2001
    ....
  21. ncbi Preserving population allele frequencies in ex situ conservation programs
    Maria Saura
    Departamento Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Conserv Biol 22:1277-87. 2008
    ....
  22. ncbi Lack of nonadditive genetic effects on early fecundity in Drosophila melanogaster
    J Fernandez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain
    Evolution 57:558-65. 2003
    ..06 +/- 0.12%). The results suggest that, for fitness-component traits, low levels of additive genetic variance are not necessarily associated with large inbreeding depression or high levels of nonadditive genetic variance...
  23. ncbi A parallel optimization approach for controlling allele diversity in conservation schemes
    Javier Vales-Alonso
    Departamento de Ingeniería Telemática, ETSI Telecomunicacion, Universidad de Vigo, Spain
    Math Biosci 183:161-73. 2003
    ..The proposed algorithm shows excellent timing and minimization performances. Execution time decreases linearly with the number of processors used, providing similar results in all cases...
  24. ncbi Phylogenetic evidence for multiple sympatric ecological diversification in a marine snail
    Humberto Quesada
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Campus As Lagoas Marcosende, 36310 Vigo, Spain
    Evolution 61:1600-12. 2007
    ..Thus, divergent selection occurring independently in different populations has produced the marine equivalent of host races, which may represent the first step in speciation...
  25. ncbi Nonallopatric and parallel origin of local reproductive barriers between two snail ecotypes
    Emilio Rolan-Alvarez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Campus Universitario, 36310 Vigo, Spain
    Mol Ecol 13:3415-24. 2004
    ..We argue that neither our laboratory hybridization experiments nor our molecular data are compatible with a model based on allopatric ecotype formation, secondary overlap and introgression...
  26. ncbi The relative contribution of band number to phylogenetic accuracy in AFLP data sets
    M J García-Pereira
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidade de Vigo, Vigo, Spain
    J Evol Biol 24:2346-56. 2011
    ..These results suggest that AFLPs may be an efficient alternative to traditional DNA sequencing for accurate topology reconstruction of shallow trees when not very short ancestral branches exist...
  27. ncbi Genetic impact of the Prestige oil spill in wild populations of a poor dispersal marine snail from intertidal rocky shores
    Jaime Piñeira
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    Mar Pollut Bull 56:270-81. 2008
    ..However, some genetic effects were detected in the polluted populations, particularly for quantitative shell traits and AFLPs, consistent with local adaptations resulting from the fuel contamination...
  28. ncbi Evaluating the relationship between evolutionary divergence and phylogenetic accuracy in AFLP data sets
    María Jesús García-Pereira
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidade de Vigo, Vigo, Spain
    Mol Biol Evol 27:988-1000. 2010
    ..Nevertheless, our data suggest that under certain circumstances, AFLPs may be suitable to reconstruct deeper phylogenies than usually accepted...
  29. ncbi A simulation study on the performance of differentiation-based methods to detect selected loci using linked neutral markers
    A Vilas
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    J Evol Biol 25:1364-76. 2012
    ..At equal conditions, bayescan seemed to perform somewhat more efficiently than dfdist/fdist, with little difference between results for dominant and codominant markers...
  30. ncbi The action of purifying selection, mutation and drift on fitness epistatic systems
    Andrés Pérez-Figueroa
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, 28040 Madrid, Spain
    Genetics 183:299-313. 2009
    ..Epistasis, either synergistic or antagonistic (this leading to multiple adaptive peaks), had no appreciable effect on MSD results nor, therefore, on the evolutionary rate of fitness change...
  31. ncbi Variation after a selective sweep in a subdivided population
    Enrique Santiago
    Departamento de Biologia Funcional, Facultad de Biologia, Universidad de Oviedo, 33071 Oviedo, Spain
    Genetics 169:475-83. 2005
    ....
  32. ncbi Palliating the impact of fixation of a major gene on the genetic variation of artificially selected polygenes
    Leopoldo Sánchez
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, 36310 Vigo, Spain
    Genet Res 88:105-18. 2006
    ....
  33. ncbi On the persistence and pervasiveness of a new mutation
    Aurora García-Dorado
    Departamento de Genetica, Facultad de Ciencias Biologicas, Universidad Complutense, 28040 Madrid, Spain
    Evolution 57:2644-6. 2003
    ..In contrast, the number of generations until fixation or loss, 2(N(e)/N)(1 + log(e)2N), is much smaller than the total number of heterozygotes. In general the number of generations is less than the number of individuals...