Research Topics
Genomes and Genes | Ruben D ArteroSummaryAffiliation: University of Valencia Country: Spain Publications
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Detail Information
Publications
Serpent and a hibris reporter are co-expressed in migrating cells during Drosophila hematopoiesis and Malpighian tubule formationRuben D Artero
Laboratory of Developmental Genetics, Dept of Genetics, University of Valencia, Dr Moliner 50, ES 46100 Burjasot, Spain
Hereditas 143:117-22. 2006..We also show that hibris function is not essential for prohemocyte migration out of the procephalic mesoderm NOR maintenance of Serpent expression in prohemocytes...
Drosophila muscleblind is involved in troponin T alternative splicing and apoptosisMarta Vicente-Crespo
Department of Genetics, University of Valencia, Valencia, Spain
PLoS ONE 3:e1613. 2008..Such transition fails in the CTG repeat expansion disease myotonic dystrophy due, in part, to sequestration of MBNL proteins by CUG repeat RNA. Four protein isoforms (MblA-D) are coded by the unique Drosophila muscleblind gene...
Genetic and chemical modifiers of a CUG toxicity model in DrosophilaAmparo Garcia-Lopez
Department of Genetics, University of Valencia, Burjasot, Spain
PLoS ONE 3:e1595. 2008..These findings provide new insights into the DM1 phenotype, and suggest novel candidates for DM1 treatments...
Generation of GAL4-responsive muscleblind constructsMa Zaida García-Casado
Department of Genetics, University of Valencia, Valencia, Spain
Genesis 34:111-4. 2002
Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicingMarta Vicente
Department of Genetics, University of Valencia, Doctor Moliner 50, Burjasot E 46100, Valencia, Spain
Differentiation 75:427-40. 2007....
In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy modelsAmparo Garcia-Lopez
Department of Genetics, University of Valencia, Burjassot E 46100, Spain
Proc Natl Acad Sci U S A 108:11866-71. 2011..In vitro, ABP1 bound to CUG hairpins and induced a switch to a single-stranded conformation. Our findings demonstrate that ABP1 shows antimyotonic dystrophy activity by targeting the core of CUG toxicity...
Noncanonical RNAs from transcripts of the Drosophila muscleblind geneJonathan M Houseley
Department of Genetics, University of Valencia, Doctor Moliner 50, 46100 Burjasot, Valencia, Spain
J Hered 97:253-60. 2006..Such noncanonical transcripts have previously been observed in vertebrates, and these data provide the first experimental evidence for similar phenomena in invertebrates...
