P Artal

..This lens is designed to mimic the situation naturally occurring in the normal healthy eye. The new proposed IOL provides an improved optical quality for all lens powers...

..However, despite its general acceptance, its magnitude and causes are still controversial. A series of experiments were performed to understand night myopia in greater detail...

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..We used adaptive optics techniques to control the eye's aberrations in order to evaluate this hypothesis...

..This suggests that an aspheric achromatic IOL may provide some visual benefit when compared to standard IOLs...

..Those results were used in computer simulations to predict the benefit of a perfect customized correction...

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..In the past decade, the use of wavefront sensing technology allowed us to complete our understating of eye optics as a robust aplanatic system...

..To propose a new objective scatter index (OSI) based in the analysis of double-pass images of a point source to rank and classify cataract patients. This classification scheme is compared with a current subjective system...

..These results suggest that the degradation of the ocular optics with age can be explained largely by the loss of the balance between the aberrations of the corneal and the internal surfaces...

..These results may suggest the presence of an auto-compensation mechanism that renders the eye's optics robust despite large variation in the ocular shape and geometry...

..For example, it shows the limitation of corneal topography as a guide for new refractive procedures and provides a strong endorsement of the value of ocular wave-front sensing for those applications...

..The technique and the instrument might contribute to the better understanding of binocular vision and to the search for optimized ophthalmic corrections...

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..In particular, this may be important to study the physiology and function of the healthy and diseased retina...

..VA ranged from decimal values of 1.0 (20/20) to 2.0 (20/10) when defocus and astigmatism were carefully corrected...

..The size of the treated area that has achieved good optical performance has been defined as the functional optical zone (FOZ). In this study the authors developed three objective methods to measure the FOZ...

..This "aberration testing station" or "visual simulator" allows us to study the relationship between specific aberrations and visual quality...

..This approach is quite powerful and is especially applicable to the study of current and future aberration-correction IOL designs...

..It allows for measuring and controlling aberrations whilst the subject might eventually perform visual tests, with no interference from the beacon light...

..We showed that the eye behaves as an aplanatic optical system, an optimized design solution rendering stable retinal image quality for different ocular geometries...

..The future use of this technique in clinical environments might help to estimate the level of corneal haze in eyes undergoing refractive surgery or/and scattering within the lens during cataract development...

..These findings may indicate a difference between emmetropic and myopic eyes that could be an important clue to understand myopia progression...

..To study how changes induced on corneal optics by myopic and hyperopic laser in situ keratomileusis (LASIK) refractive surgery affect the aberration compensation mechanism...

..This instrument might be useful to explore the possible connections between changes in ocular structures and the associated pathologies...

..The results are particularly important for visual simulation and ophthalmic testing applications, although they are equally interesting for any adaptive optics application with liquid crystal based devices...

..The authors examined the optical properties of Bangerter foils and compared them with the effect of defocus...

..The combination of the two techniques can accurately measure complicated phase profiles, combining the robustness of the HS and the higher resolution and dynamic range of the PDI...

..This is actually the situation in older eyes with both spherical aberration and intraocular scatter being higher than in young eyes...

..The purposes of this study are to explore the effect of astigmatism and high-order aberrations of progressive-power lenses (PPLs) on visual acuity (VA) and to find a good optical metric for evaluating visual performance of PPLs...

..Therefore, higher-order aberrations have a minimal impact on the optical performance of these lenses...

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..This instrument allows useful information on both the optical and the biomechanical properties of the eye to be obtained...

..To study the effect of small-incision cataract surgery on the optical aberrations of the cornea...

..To measure the wavefront aberration at different locations in progressive-power lenses (PPL's) isolated and in situ (PPL's plus eye)...

..However, neither the latency time nor the precision of the accommodation were affected. These results may indicate that the monochromatic aberrations play a role in driving the accommodation response...

..We explored the potential of aberration correction in the human eye by using a new generation of soft contact lenses with aspheric and asymmetric surfaces...

..We discuss details of the system and describe cone-mosaic images obtained under different conditions...

..To evaluate how ocular optical image quality and psychophysical estimates of visual performance compare to each other as a function of defocus...

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..We apply this knowledge to a detailed study of the relationship between the Stiles-Crawford effect and its optical counterpart...

..Lett. 29, 968 (2004)] together with a detailed numerical analysis of the device. The outcome is compared with experimental results...

..We did find differences in pupil size with mono- and binocular vision but the pupil size temporal dynamics did not behave in the same way as the aberrations' dynamics...

..In conclusion, the combination of the ocular transverse chromatic aberration and monochromatic aberrations accounts for the loss in visual sensitivity found with a decentered small pupil at low and intermediate spatial frequencies...

..To our knowledge, this is the first report of a device to objectively determine the spectral fluctuations in the ocular wavefront...

..Measurements in real eyes were conducted to examine the level and optical quality of the correction. We also performed some tests to evaluate the effect of the corrector on visual performance...

..Comparison of wave-fronts aberrations from right and left eye in 35 subjects, showed a good correlation between most of the second- and third-order terms and a slight (but not clear) tendency for mirror symmetry between eyes...

..However, quite different estimates of the retinal image quality are obtained for combinations of polarization states in both the first and the second passes in the double-pass apparatus...

..Such studies are essential first steps towards a future high-resolution optical characterization technique for simultaneous corneal surgery and wound healing of the human eye...

..To report an advanced optical procedure developed for the diagnosis of a particular case of diplopia...

..To assess the performance and optical limitations of standard, aspheric, and wavefront-customized intraocular lenses (IOLs) using clinically verified pseudophakic eye models...

..The greatest influence on visual acuity of neutralizing the SCE, across the subjects and range of conditions, was deterioration of 0.06 (4-mm pupil), 0.16 (6-mm pupil), and 0.29 log unit (7.6-mm pupil)...

..To explore the impact of spherical aberration (SA) on contrast sensitivity using an adaptive optics vision simulator to determine the optimal amount of SA to include in customized corrections of wavefront aberrations...

..Neural adaptation slightly modifies the best aberration correction, although this effect averaged only approximately 12% of complete adaptation. These results may have practical consequences for customized vision correction...

..The finding of general peripheral myopia was unexpected. Its possible roles in foveal refractive development are discussed...

..In this study, adaptive optics techniques were used to evaluate the potential advantages and disadvantages associated with intraocular lenses (IOLs) with modified spherical aberration profiles...

..This study showed that, in those cases, the double-pass technique is a complementary tool for better estimation of ocular optical quality...

..Volumetric UHR OCT of the living retina, obtained with up 25,000A-scans/s and high resolution enables visualization of retinal features that might correspond to groups of terminal bars of photoreceptors at the external limiting membrane...