M Alegre

..The aim of our work was to study the changes in local field potentials (LFP) recorded from the subthalamic nucleus (STN) and their relationship with cortical activity, during movement observation...

..Diphasic dyskinesias are a subtype of levodopa-induced dyskinesias that appear typically at the onset and end of levodopa antiparkinsonian action. The pathophysiology of diphasic dyskinesias is not well understood...

..Given the relationship between the mirror system and theory of mind, we hypothesize that TOM deficits in PD might be at least partially mediated by mirror system dysfunction...

..When dyskinesias were only present in one limb (n = 2), the 4-10 Hz peak was only recorded in the contralateral STN. These findings suggest that the 4-10 Hz oscillation is associated with the expression of LID in Parkinson's disease...

..Our aim was to study the oscillatory changes related to the forced termination of a single complex motor program (signature) and compare them with those observed after the normal termination of the movement...

..The beta-ERD was significantly larger in the imitation paradigm. Our results show that the motor preparation mechanisms involved in an imitated and a non-imitated movement are different...

..Gamma band activity may be just involved in the execution of the movement, related to muscle contraction...

..The response around 200 ms may be involved in auditory mismatch and/or memory retrieval, and late activity is probably a P300-related response. Attention enhances all these activities...

..002) to the latency of the P300 wave. CONCLUSIONS: EEG signal analysis with wavelet transform allows the identification of an early oscillatory cortical response in the gamma frequency range, as well as a late P300-related response...

..These findings should be taken into account when assessing the changes in cortical oscillatory activity related to different drugs, in healthy rodents and in animal models of neurodegenerative diseases...

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..These results suggest that movement-related activity in the STN has, by and large, a bilateral representation and probably reflects cortical input...

..In summary, our findings support the active and adaptive concept of brain function that has emerged over recent years, suggesting that the match of sensory information with memory contents generates gamma oscillations...

..In spite of the advances of recent years, 20-30% of patients diagnosed with epilepsy are not really epileptic, a fact that it is excessive and unacceptable...

..SIGNIFICANCE: Our findings provide new insight on the relationship between the decision-making process, movement, and cortical oscillatory activity...

..Our finding suggests that the inferior portion of the banks of the parieto-occipital sulci contains association visual cortex involved in the processing of stimuli that can be as simple as a flickering light source...

..Auditory amplitude modulation following responses (AMFR), are oscillatory steady-state responses to rhythmic auditory stimuli that indirectly measure brain synchrony...

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..These findings suggest that afferent proprioceptive inputs may play a role in the final part of the beta ERD observed during voluntary movements...

..This is the reason for our proposal of a new nomenclature for BAEP waveforms in monkeys, following a descriptive order with Arabic numerals preceded by the letter M...

..More experience on this subject is needed to establish a correlation between intraoperative results and postoperative stimulator function...

..Our aim was to develop a fast technique to explore the oscillatory response to auditory stimuli, using a tone modulated in amplitude by a sinusoid whose frequency increases linearly in frequency ('chirp') from 1 to 120 Hz...

..The emergence of new activities does not seem to be a relevant mechanism in the formation of these components...

..The periodic limb movements disorder (PLMD) is frequently associated with the obstructive sleep apnea syndrome (OSAS), but the prevalence and clinical relevance of this association have not been studied in detail...

..We review the mechanisms that may involved in the pathophysiology of dystonia...

..This review discusses all these aspects, with emphasis on their potential role both as a basic mechanism in brain function and as a pathophysiological substrate for some of the symptoms and signs observed in several diseases...

..Recovery was fast, but treatment with pacemaker must be considered...

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..However, if present it points out to a contralateral seizure onset. In our series it happened in patients with frontal seizures. The EEG may help to clarify if it correspond to a true postictal phenomenon or to a ictal paralysis...

..The mean number of AED taken per patient increased.Conclusions: LTG is a safe an effective drug in epilepsy. It has a clear impact in the management of the epileptic patients...